* A good Centaur can catch Queen of Pain with a Blink Dagger and Hoof Stomp.
* Retaliate with Blade Mail reflects all of Queen of Pain's damage, especially Sonic Wave.
* Stampede grants a movement speed bonus, which can prevent Queen of Pain from initiating.
* Double Edge can shred her low health pool if she's not careful.

* Hoof Stomp and Double Edge can often burst down Phantom Assassin from early to mid game.
* Retaliate makes it very unlikely for Phantom Assassin to win the lane against Warrunner. Double Edge can also be used to wear her down, as she has a much smaller health pool than that of Centaur Warrunner until purchasing a Ring of Health. Stifling Dagger will also trigger Retaliate and Blur cannot evade Retaliate.
* Centaur Warrunner's tankiness in combination with armour items that Axe often purchases like Blade Mail, Crimson Guard, Assault Cuirass and Shiva's Guard can make Phantom Assassin's attacks only tickle Centaur Warrunner.
* Centaur Warrunner just has to be careful about Fan of Knives from Aghanim's Shard and Coup De Grace, as Fan of Knives can disable Retaliate even if Centaur Warrunner is spell immune.
Additional:
* Hoof Stomp and Double Edge can often burst down Phantom Assassin from early to mid game.
* Retaliate makes it very unlikely for Phantom Assassin to win the lane against Warrunner. Double Edge can also be used to wear her down, as she has a much smaller health pool than that of Centaur Warrunner until purchasing a Ring of Health. Stifling Dagger will also trigger Retaliate and Blur cannot evade Retaliate.
* Centaur Warrunner's tankiness in combination with armour items that Axe often purchases like Blade Mail, Crimson Guard, Assault Cuirass and Shiva's Guard can make Phantom Assassin's attacks only tickle Centaur Warrunner.
* Centaur Warrunner just has to be careful about Fan of Knives from Aghanim's Shard and Coup De Grace, as Fan of Knives can disable Retaliate even if Centaur Warrunner is spell immune.

* A good Nyx can reflect Queen of Pain's Sonic Wave with his Spiked Carapace, or even initiate a gank on her in Vendetta while she farms a creep wave with Scream of Pain.
* Her strength to intelligence ratio is bad enough that he should be able to kill her without even requiring a Dagon, provided he can get his full combo off.

* Heroes with heavy early and mid-game magical damage are also problematic for Phantom Assassin due to being able to easily kill her before she gains an item advantage: Lina, Necrophos, Nyx Assassin, Gyrocopter. Should be noted these heroes are usually quite squishy and don't scale well with health. So to some respect, they are on a time crunch.

* Heroes with gap closing abilities will be easy targets for Berserker's Call: Phantom Assassin, Faceless Void, Slark, Chaos Knight, Morphling, Queen of Pain

Additional:
* Berserker's Call prevents Queen of Pain from escaping with Blink and also pierces her Black King Bar.
* Due to her fast attack speed from Mjollnir, it will quickly trigger Counter Helix.
* Culling Blade finishes off Queen of Pain's low health pool before she gets a chance to escape, preventing her from playing the hit-and-run style often associated with Queen of Pain.

* Phantom Strike's extra attack speed will cause Phantom Assassin to trigger Counter Helix more often, which can be fatal for Phantom Assassin. Jumping on Axe with Phantom Strike is not a good idea for Phantom Assassin at all as it makes her a seriously easy target for a counter-initiation with Berserker's Call and Blade Mail.
* Most of Axe's abilities pierce Black King Bar, allowing him to lock down Phantom Assassin at any time.
* Berserker's Call greatly reduces Phantom Assassin's ability to crit hard against Axe, and may cause her to kill herself when used with Blade Mail. Berserker's Call can also affect Phantom Assassin even if she has Black King Bar active as Berserker's Call can fully pierce spell immunity, making Berserker's Call one of the best abilities in the game against heroes like Phantom Assassin who wants to kill opponents quickly without being interrupted.
* Culling Blade can often kill Phantom Assassin before she can do anything due to her low health and strength gain. And every time Culling Blade successfully kills Phantom Assassin or any of her teammates, Axe gains permanent armor from it, which in combination with armor items that Axe often purchases like Blade Mail, Crimson Guard, Assault Cuirass and Shiva's Guard can make Phantom Assassin's attacks only tickle Axe.
* Aghanim's Shard upgraded Counter Helix can weaken Phantom Assassin's damage output, and if her attack damage is weak, Coup De Grace will also suffer from attack damage reduction as well.
Additional:
* Phantom Strike's extra attack speed will cause Phantom Assassin to trigger Counter Helix more often, which can be fatal for Phantom Assassin in the early game. Jumping on Axe with Phantom Strike is not a good idea for Phantom Assassin at all as it makes her a seriously easy target for a counter-initiation with Berserker's Call and Blade Mail.
* Most of Axe's abilities pierce Black King Bar, allowing him to lock down Phantom Assassin at any time.
* Berserker's Call greatly reduces Phantom Assassin's ability to crit hard against Axe, and may cause her to kill herself when used with Blade Mail. Berserker's Call can also affect Phantom Assassin even if she has Black King Bar active as Berserker's Call can fully pierce spell immunity, making Berserker's Call one of the best abilities in the game against heroes like Phantom Assassin who wants to kill opponents quickly without being interrupted.
* Culling Blade can often kill Phantom Assassin before she can do anything due to her low health and strength gain. And every time Culling Blade successfully kills Phantom Assassin or any of her teammates, Axe gains permanent armor from it, which in combination with armour items that Axe often purchases like Blade Mail, Crimson Guard, Assault Cuirass and Shiva's Guard can make Phantom Assassin's attacks only tickle Axe.
* Blade Mail is an item that Axe purchases every game, and which can be used to turn Phantom Assassin's critical strikes from Coup De Grace against herself. This can become even worse if she's affected by Berserker's Call, as she has no way to stop attacking.
* Aghanim's Shard upgraded Counter Helix can weaken Phantom Assassin's damage output, and if her attack damage is weak, Coup De Grace will also suffer from attack damage reduction as well.
* Axe just has to be careful about Fan of Knives from Aghanim's Shard and Coup De Grace, as Fan of Knives can disable Counter Helix, even if Axe is spell immune.

* Blood Rite prevents Queen of Pain from escaping with Blink.
* Blink will trigger the extra damage from Rupture.
Additional:
* Blood Rite silences her, preventing her from initiating or escaping.
* With Thirst, even if she Blinks away, Bloodseeker can catch right up to her.
* Rupture will heavily damage Queen of Pain if she tries to Blink away.
* She is, however, one of the few heroes who can avoid the damage from Rupture if she successfully blink-walks.

* Heroes with gap-closing abilities who attempt to use them for escaping Bloodseeker will suffer serious damage from Rupture: Phantom Assassin, Anti-Mage, Faceless Void, Riki, Slark, Spirit Breaker.

* Blink and positioning is crucial for Queen of Pain. These factors are heavily countered by a good Glimpse.
* Static Storm is devastating for Queen as she relies heavily on her spells to inflict heavy burst damage.
Additional:
* Thunder Strike gives vision of Queen of Pain when she's trying to escape. When combined with Glimpse, her mobility and hit-and-run style can be negated.
* While in a team fight, Static Storm forces Queen of Pain to only use right-clicks.
* When combined with the Kinetic Field, she can only wait until she respawns.

* Doom, Disruptor with Aghanim's Scepter, and hex abilities all prevent item usage, which is a severe problem for Phantom Assassin as it prevents her from using Black King Bar, the one item that helps protect her against the aforementioned dangers. Doom and Shadow Demon with Aghanim's Scepter also disables Phantom Assassin's Evasion and Critical Strike, removing much of her damage and survivabaility.

* Heroes that depend on disrupting fights with ability combos or big ultimate abilities are vulnerable to the long stun of Fiend's Grip: Disruptor, Death Prophet, Enigma, Faceless Void, Invoker, Lich, Magnus, Mars, Medusa, Outworld Destroyer, Phoenix, Puck, Queen of Pain, Shadow Fiend, Treant Protector, Underlord, Winter Wyvern, Witch Doctor, Zeus.

* Enfeeble greatly reduces Phantom Assassin's attack damage, and if her attack damage is weak, Coup De Grace will also suffer from attack damage reduction as well. Enfeeble also reduces any healing Phantom Assassin receives, making her unable to heal herself with Phantom Strike, and it also reduces cast range of Phantom Assassin's abilities, making her unable to harass with Stifling Dagger and to use Phantom Strike at longer distances.
* Nightmare and Fiend's Grip can ground Phantom Assassin, who normally blinks around with Phantom Strike, and stop her from outputting damage, even with Black King Bar.
* Phantom Assassin's low health pool early on makes her susceptible to Brain Sap and Fiend's Grip's heavy nuke damage.
Additional:
* Enfeeble greatly reduces Phantom Assassin's attack damage, and if her attack damage is weak, Coup De Grace will also suffer from attack damage reduction as well. Enfeeble also reduces any healing Phantom Assassin receives, making her unable to heal herself with Phantom Strike, and it also reduces cast range of Phantom Assassin's abilities, making her unable to harass with Stifling Dagger and to use Phantom Strike at longer distances.
* Nightmare and Fiend's Grip can ground Phantom Assassin, who normally blinks around with Phantom Strike, and stop her from outputting damage, even with Black King Bar.
* Phantom Assassin's low health pool early on makes her susceptible to Brain Sap and Fiend's Grip's heavy nuke damage.

* High priority targets like Queen of Pain, Drow Ranger and even Anti-Mage can't get caught out from Lion's long range disables.

* Despite her high mobility, Hex or Earth Spike can lock Phantom Assassin down and make her vulnerable.
* Although she has high evasion through Blur, Phantom Assassin has a rather low health pool, making her weak to Lion's magical burst.

* A good Skywrath Mage with quick fingers will punish Queen of Pain for blinking aggressively. Ancient Seal is a six second silence with no cast time, so he can interrupt either her Shadow Strike or Sonic Wave, and a good Mystic Flare on top of that will seal the deal for her.
* Ancient Seal also has pretty good range so he could get it off before she blinks away.

* While Phantom Assassin can kill Skywrath Mage in a few strikes, Skywrath Mage can also do the same to her if she is not careful.
* Arcane Bolt's long range and low cooldowns allows Skywrath Mage to severely harass Phantom Assassin in lane.
* Ancient Seal prevents Phantom Assassin from escaping or engaging with Phantom Strike.
* Mystic Flare's heavy magical damage nukes Phantom Assassin down quickly during the early to mid game.
Additional:
* While Phantom Assassin can kill Skywrath Mage in a few strikes, Skywrath Mage can also do the same to her if she is not careful.
* Arcane Bolt's long range and low cooldowns allows Skywrath Mage to severely harass Phantom Assassin in lane.
* Ancient Seal prevents Phantom Assassin from escaping or engaging with Phantom Strike.
* Mystic Flare's heavy magical damage nukes Phantom Assassin down quickly during the early to mid game.

* Aggressively blinking is not going to end well against Luna, because Queen of Pain will be an easy target for Lucent Beam & Eclipse.
* Queen of Pain's HP is abysmal, so Luna can quickly kill Queen of Pain as soon as she initiates with Blink.
Additional:
* Aggressively blinking is not going to end well against Luna, because Queen of Pain will be an easy target for Lucent Beam & Eclipse.
* Queen of Pain's HP is abysmal, so Luna can quickly kill Queen of Pain as soon as she initiates with Blink.

* Even though Phantom Assassin can easily kill Luna in few strikes, Luna can also do the same to Phantom Assassin if she is not careful.
* An ill-timed and ill-positioned Phantom Strike will make Phantom Assassin an easy target for counter-attack with Eclipse if she does not have Black King Bar available to use and if Phantom Assassin cannot kill Luna fast enough. This can be even better if Luna buys Aghanim's Scepter.
* Moon Glaives can ignore Blur's evasion if Luna attacks an enemy near Phantom Assassin.
* Luna can counter Blur's evasion by buying either Silver Edge, or Monkey King Bar, which are common items on Luna.
* Luna just has to be careful about Fan of Knives and Aghanim's Shard and Coup De Grace , as Fan of Knives can disable Moon Glaives and Lunar Blessing while Coup De Grace can deal serious damage to her even if she is spell immune, though this issue can be solved by buying Ethereal Blade, which is a situational item on Luna.
Additional:
* Even though Phantom Assassin can easily kill Luna in few strikes, Luna can also do the same to Phantom Assassin if she is not careful.
* An ill-timed and ill-positioned Phantom Strike will make Phantom Assassin an easy target for counter-attack with Eclipse if she does not have Black King Bar available to use and if Phantom Assassin cannot kill Luna fast enough. This can be even worse if Luna buys Aghanim's Scepter.
* Moon Glaives can ignore Blur's evasion if Luna attacks an enemy near Phantom Assassin.
* Luna can counter Blur's evasion by buying either Silver Edge, or Monkey King Bar, which are common items on Luna.
* Luna just has to be careful about Fan of Knives from Aghanim's Shard and Coup De Grace, as Fan of Knives can disable Moon Glaives and Lunar Blessing while Coup De Grace can deal serious damage to her even if she is spell immune, though this issue can be solved by buying Ethereal Blade, which is a situational item on Luna.

* In early to mid stage, Silence is also a great way to counter escape oriented heroes such as Anti-Mage, Queen of Pain, and Phantom Assassin to prevent them from escaping, provided that they don't have any basic dispels.

Additional:
* Silence will prevent Queen of Pain from using Blink to escape or chase.
* If Queen of Pain uses Blink to close the gap to Death Prophet, Death Prophet will be in range for Spirit Siphon and typically gain an advantage over Queen of Pain.

* In early to mid stage, Silence is also a great way to counter escape oriented heroes such as Anti-Mage, Queen of Pain, and Phantom Assassin to prevent them from escaping, provided that they don't have any basic dispels.

* Heroes who rely on high mobility are especially vulnerable to Primal Roar: Storm Spirit, Ember Spirit, Queen of Pain.

* Heroes with disables that ignore spell immunity will render Phantom Assassin quite useless in teamfights throughout the game: Axe, Enigma, Vengeful Spirit, Doom, Bane, Beastmaster, Pudge, Medusa.

* Heroes that have escape abilities (such as Queen of Pain, Storm Spirit or Timbersaw) can be either nullified by Reaper's Scythe or a complimentary item for Necrophos (like Rod of Atos or Scythe of Vyse). If Necrophos is quick enough and enters range, they can quickly, if not instantly, die if they are not quick enough.

* Heroes who rely on physical damage are easily negated by Ghost Shroud: Phantom Assassin, Wraith King, Juggernaut.

* Tinker can use Laser to save an ally or himself from Phantom Assassin's initiate Phantom Strike due to the blind, forcing her to use a Black King Bar to effectively initiate, Tinker can also use Warp Flare one he buys Aghanim's Shard to reverse Phantom Strike's blinking with Phantom Strike.
* Tinker almost never uses his physical attack, relying on his spell-spamming to deal damage which ignores Blur's Evasion
* Defense Matrix prevents Coup de Grace from triggering.

* Purification and Hammer of Purity can easily catch Phantom Assassin once she jumps with Phantom Strike in to attack.
* Heavenly Grace can be used to dispel slow from Stifling Dagger, and disables from the items Phantom Assassin relies on.
* Phantom Assassin depends entirely on physical attacks and her damage output is 100% physical. Therefore, since she has no any sources of magical damage output and hates going for items that deal magical damage like Dagon, Ethereal Blade and Revenant's Brooch, Guardian Angel will render her completely useless.
* Purification, Heavenly Grace and Guardian Angel can be used to save an allied hero before Phantom Assassin can finish them off with Coup De Grace.
Additional:
* Purification and Hammer of Purity can easily catch Phantom Assassin once she jumps with Phantom Strike in to attack.
* Heavenly Grace can be used to dispel slow from Stifling Dagger, and disables from the items Phantom Assassin relies on.
* Phantom Assassin depends entirely on physical attacks and her damage output is 100% physical. Therefore, since she has no any sources of magical damage output and hates going for items that deal magical damage like Dagon, Ethereal Blade and Revenant's Brooch, Guardian Angel will render her completely useless.
* Purification, Heavenly Grace and Guardian Angel can be used to save an allied hero before Phantom Assassin can finish them off with Coup De Grace.

* Phantom Assassin's single target abilities make her very helpless against swarms of Spiderlings without Battle Fury.
* Because Phantom Assassin is always reliant on critical strikes, Broodmother will usually have enough time to use Spin Web to save herself.
* Silken Bola can cripple Phantom Assassin greatly due to her being 100% reliant on physical attacks.
Additional:
* Phantom Assassin's single target abilities make her very helpless against swarms of Spiderlings without Battle Fury.
* Because Phantom Assassin is always reliant on critical strikes, Broodmother will usually have enough time to use Spin Web to save herself.
* Silken Bola can cripple Phantom Assassin greatly due to her being 100% reliant on physical attacks.

* Overgrowth prevents Phantom Assassin from using Blink Strike even through her spell immunity.
* Living Armor reduces Phantom Assassin's physical damage whenever she attempts to gank an allied hero.

* Sonic Wave is a bad choice in abilities if he and the Tempest Double both use Blade Mail to reflect the damage to Queen of Pain, potentially killing her outright if her health is low enough.
* Magnetic Field protects himself or his ally from Queen of Pain's attacks unless she has Monkey King Bar.
* One more advantage of Tempest Double is that he can deny himself if he is close to death with Shadow Strike's debuff.

* Night Stalker has a huge, almost instant silence through Crippling Fear. The main problem is that he can get it off while Queen of Pain barely has any vision of him if he creeps up to her during Dark Ascension. She'll have to play very carefully before she gets a Black King Bar or a Eul's Scepter of Divinity.

* Dispersion makes it hard for Phantom Assassin to burst down Spectre while also reflecting back Phantom Assassin's high burst damage against herself.
* Desolate ignores the evasion from Blur.
* Black King Bar is useless for Phantom Assassin against Spectre as all of her skills pierce spell immunity.
* Spectre only needs to be careful against Fan Of Knives from Aghanim's Shard, as it can disable Desolate and Dispersion, though this issue can be solved by buying Blade Mail, which is a common item on Spectre.
Additional:
* Dispersion makes it hard for Phantom Assassin to burst down Spectre while also reflecting back Phantom Assassin's high burst damage against herself.
* Desolate ignores the evasion from Blur.
* Black King Bar is useless against Spectre as all of her skills pierce spell immunity.

* Duels prevents Queen of Pain from using Blink, which may force her to purchase a Linken's Sphere
* Because Queen of Pain is also not a right-click hero, Legion won't have much difficulties in duels.
* Press the Attack dispels Shadow Strike's debuff.

* Pit of Malice prevents Phantom Assassin from either escaping or engaging with Phantom Strike.
* Phantom Assassin's damage output is entirely physical, therefore Atrophy Aura Atrophy Aura is very hazardous for her in most of the stages, particularly since it also affects Coup De Grace Coup de Grace, hindering Phantom Assassin's main source of damage.
* Without proper items and any area-of-effect ability/item, Phantom Assassin cannot stop Underlord and his team to escape with Fiend's Gate, nor she can intercept them if Underlord chooses to teleport on any area of the map.
Additional:
* Pit of Malice prevents Phantom Assassin from either escaping or engaging with Phantom Strike.
* Phantom Assassin's damage output is entirely physical, therefore Atrophy Aura Atrophy Aura is very hazardous for her in most of the stages, particularly since it also affects Coup De Grace Coup de Grace, hindering Phantom Assassin's main source of damage.
* Without proper items and any area-of-effect ability/item, Phantom Assassin cannot stop Underlord and his team to escape with Fiend's Gate, nor she can intercept them if Underlord chooses to teleport on any area of the map.

* Fire Spirits applies a severe attack speed slow, severely hindering Phantom Assassin's damage output.
* Phantom Assassin cannot cast Phantom Strike on Phoenix during Supernova.
Additional:
* While her Phantom Strike does give limited extra attack speed, she cannot use the ability against the Phoenix Sun, and while her Blur may protect her from attacks, Phoenix's strong magical DPS burns away her small health pool quickly, and the attack speed slow makes her unable to fight back (provided she has no source of spell immunity).

* Whirling Axes (Melee) makes it hard to land a Coup De Grace.
* Troll Warlord often buys Silver Edge and Monkey King Bar, the items that greatly help against Phantom Assassin's Blur ability.
* Battle Trance completely negates Phantom Assassin's large damage output, preventing Troll Warlord from dying easily. The lifesteal also allows Troll Warlord to restore much of his health.
Additional:
* Troll Warlord can build a Silver Edge or a Monkey King Bar to completely ignore Blur.
* Whirling Axes (Melee) provides a 60% miss chance, making a Coup de Grace critical strike very hard to land.
* Battle Trance negates Coup de Grace, preventing Troll Warlord from dying to her critical hits.

* Phantom Assassin relies on her Blur to stay alive, but is very vulnerable to Sand King's heavy magic damage.
* With Burrowstrike, Sand King can often catch Phantom Assassin before she can use her Black King Bar.
* Sand King can dodge Stifling Dagger with Sandstorm.
* Phantom Assassin has a hard time killing Sand King because of his high mobility.

* Phantom Assassin is known to be weak against bursts of magical damage, something Primal Beast excels at from the beginning of the game. He can use this to his advantage by constantly hunting Phantom Assassin down, especially if she is left alone to farm.
* Primal Beast is a good carrier of Ethereal Blade, Vanguard and Shiva's Guard all of which are very good against Coup de Grace and Phantom Strike.
* Even though Primal Beast does alot of physical damage early on, later once Blur becomes more potent, she may find herself being overwhelmed by Trample and Pulverize instead.
* Primal Beast also has a level 25 talent which makes Pulverize go through spell immunity which is especially effective against a hero like Phantom Assassin who relies on it.

* Shadow Shaman has many disables to lock down Queen of Pain, preventing her from Blinking away, even through Linken's Sphere or her spell block talent.
* Mass Serpent Ward can tear through Queen of Pain's low health pool once she's locked down by Hex & Shackles.

* Phantom Assassin's Blur will be useless if Windranger managed to get Monkey King Bar or Bloodthorn, and other than Stifling Dagger, Phantom Assassin has no abilities that can bypass Windrun.
* Additionally, Phantom Assassin doesn't like building Monkey King Bar because her crits are reliant on attack damage.
* Focus Fire can still deal considerable damage despite Blur's evasion due to the increased attack speed.

* Any Hero with high mobility will be neutralized by dream coil: Queen of Pain, Storm Spirit, Ember Spirit, Lycan, Bloodseeker, Anti-Mage, Timbersaw

Additional:
* Puck will make a game of dodging as many Shadow Strikes as he can with Phase Shift. If he's a good player, he will also dodge Sonic Wave. If he's a great player, he will also dodge Scream of Pain. All through a single spell.
* Puck also has a silence to stop her blink with Waning Rift.
* Puck will have vision to hunt her down if she blinks into the trees with Illusory Orb.
* If Queen of Pain is under the effect of Dream Coil, she will be unable to blink out.

* Puck relies mainly on magical burst damage, which Phantom Assassin is most vulnerable against.
* Phase Shift and Illusory Orb disjoint Stifling Dagger, also allowing to kite Phantom Assassin.
* Dream Coil will stun Phantom Assassin if she uses Phantom Strike to blink away.

* Phantom Assassin does not deal with early aggression very easily (especially when magical damage). A competent Batrider can make life very difficult with Sticky Napalm followed by any other spell.

* Time Dilation affects Queen of Pain's low cooldown abilities, making them unusable for a long time, rendering Queen of Pain nearly useless.
* Chronosphere provides excellent lockdown against Queen of Pain, allowing for reliable kills in all stages of the game.
Additional:
* Time Walk and Backtrack allows Faceless Void to easily negate Queen of Pain's burst damage.
* Chronosphere prevents Queen of Pain from escaping with Blink, and her low survivability makes her an easy kill.
* Time Dilation will prevent Queen of Pain from using her low-cooldown spells or force her to buy Black King Bar or a Eul's Scepter of Divinity to dispel the debuff and re-engage.

* Sharpshooter disables both Blur and Coup De Grace, especially with the level 25 talent.
* Because Phantom Assassin is often reliant on critical strikes, Hoodwink can have enough time to simply move near a tree and escape with Scurry.
Additional:
* Sharpshooter disables both Blur and Coup De Grace, especially with the level 25 talent.
* Because Phantom Assassin is often reliant on critical strikes, Hoodwink can have enough time to simply move near a tree and escape with Scurry.

* Ghostship helps your team soak up damage from Sonic Wave and Scream of Pain.
* Queen of Pain can't escape easily from X Marks the Spot - Torrent combo.

* Phantom Assassin's high physical damage is greatly reduced by Bulwark.
* God's Rebuke has true strike, ignoring the evasion from Blur.

* Morphling's naturally high armor thanks to his high agility makes it hard for Phantom Assassin to take him down with Coup de Grace.

* Chain of Earthbinds prevents her from using Blink, allowing Meepo to quickly kill her with Poof and attacks.
* Meepo tends to buy items with attributes, mitigating Queen of Pain's magical burst.
Additional:
* Meepo is the hard counter for Queen of Pain - chaining Earthbinds prevents her from using Blink for a long time, and without any other escape options, Queen of Pain cannot survive several Poofs and attacks.
* Meepo tends to build items with attributes, mitigating Queen of Pain's magical burst.

* Heroes with high mobility can be prevented from using it to their advantage with Earthbind, even if they pack a dangerous arsenal: Earth Spirit, Ember Spirit, Storm Spirit, Nature's Prophet, Phantom Assassin, Riki, Anti-Mage, Weaver.
* See items and abilities disabled by roots

* Heroes who just want to farm and avoid Lone Druid early will find it very hard to do so when he starts knocking on towers: Templar Assassin, Phantom Assassin, Ember Spirit, Morphling.

* Fate's Edict cripples many heroes who rely on attacks, such as Phantom Assassin, Sven, or Enchantress, without a dispel or a Black King Bar.

* Any heroes with low mana pools will die quickly or even instantly to Sanity's Eclipse: Doom, Phantom Assassin, Troll Warlord.

* Heroes with illusions and summons can be hard for Phantom Assassin to deal with, as she lacks any AoE abilities to deal with them without items: Broodmother, Phantom Lancer, Chaos Knight, Naga Siren, Terrorblade.

* Heroes with disables that ignore spell immunity will render Phantom Assassin quite useless in teamfights throughout the game: Axe, Enigma, Vengeful Spirit, Doom, Bane, Beastmaster, Pudge, Medusa.

* Heroes with mobility spells like Queen of Pain, Anti-Mage, Phantom Assassin, Riki, Puck, and Spirit Breaker that are cancelled by Frostbite can suffer greatly from the presence of Crystal Maiden. It is absolutely critical, however, to have followup from teammates, as all of the above heroes can make quick work of the squishy Crystal Maiden after they are released from her grip.

* Though certainly not a "hard counter", Crystal Maiden's skillset (magical damage nukes) does pose a substantial threat to Phantom Assassin through the mid game, especially if followed up with engagement by her team.
* A quick use of Freezing Field directly after Phantom Strike can leave Phantom Assassin trapped inside the area of effect, capitalizing on Phantom Assassin's relatively low HP pool when she is not protected by Blur, and besides Skull Basher, Phantom Assassin hates buying disabling items like Scythe of Vyse or Eul's Scepter of Divinity.
* If Phantom Assassin chooses not to buy a Black King Bar relatively early, the attack slow from Freezing Field can greatly hinder the proc chance of Coup de Grace in a teamfight.
* However, Phantom Assassin's massive damage, and her tendency to build both Black King Bar and Skull Basher makes her a formidable foe the later the game goes, and fighting her without a team is almost never a good choice.

* Heroes such as Lone Druid, Tidehunter and Viper can be very problematic for Phantom Assassin because they give her very little time to farm and become scary.

* Heroes that rely on escapes to stay alive can be caught and locked down for a long time: Queen of Pain, Phantom Assassin

* Heroes that rely on escapes to stay alive can be caught and locked down for a long time: Queen of Pain, Phantom Assassin

* Many physical-only single-target heroes like Lifestealer, Sven, Wraith King, Phantom Assassin, Templar Assassin can have their damage mitigated by Cold Embrace.

* Heroes who cannot prevent Sven from killing towers will often struggle from a small map very early, such as Phantom Assassin, Storm Spirit and Phantom Lancer.

* Heroes with illusions and summons can be hard for Phantom Assassin to deal with, as she lacks any AoE abilities to deal with them without items: Broodmother, Phantom Lancer, Chaos Knight, Naga Siren, Terrorblade.

* Heroes that can apply early pressure before Phantom Assassin has farm are massive threats: Axe, Viper, Meepo, Pugna, Slark etc.

* An Aghanim's Scepter upgraded Doom can be useful against heroes with troublesome passive skills while also disabling them for a long time: Phantom Assassin, Enchantress, Huskar, Underlord.

* Heroes with disables that ignore spell immunity will render Phantom Assassin quite useless in teamfights throughout the game: Axe, Enigma, Vengeful Spirit, Doom, Bane, Beastmaster, Pudge, Medusa.

* Heroes that rely on physical damage are ineffective against Dragon Knight due to his high armor: Phantom Assassin,Bloodseeker, Lifestealer, Troll Warlord, Sven

* Heroes with illusions and summons can be hard for Phantom Assassin to deal with, as she lacks any AoE abilities to deal with them without items: Broodmother, Phantom Lancer, Chaos Knight, Naga Siren, Terrorblade.

* Reactive Armor helps Timbersaw sustain harassment from Stifling Dagger.
* Phantom Assassin has a moderate health pool and usually appears in the front line of battle, making her vulnerable to Timbersaw's magic burst.
* Timbersaw can easily escape from Phantom Assassin thanks to his Timber Chain.
Additional:
* Reactive Armor helps Timbersaw sustain harassment from Stifling Dagger, as well as ganking attempts.
* Phantom Assassin is a hero with moderate HP pool, and usually appears in the front line of battle. Because Blur does nothing against spells, she is vulnerable to Timbersaw's skills.
* Timbersaw can easily escape from Phantom Assassin thanks to his Timber Chain.

* Heroes with blink or movement abilities, which are disabled by Pounce's leash: Anti-Mage, Earth Spirit, Faceless Void, Magnus, Mirana, Monkey King, Morphling, Pangolier, Phantom Assassin, Phoenix, Puck, Queen of Pain, Riki, Sand King, Spirit Breaker, Timbersaw, Tusk.

* Heroes that can apply early pressure before Phantom Assassin has farm are massive threats: Axe, Viper, Meepo, Pugna, Slark etc.

Additional:
* Slark's Pounce allows him to close the gap on Phantom Assassin and prevent her from escaping with Phantom Strike.
* As a hero who typically builds Silver Edge, Slark can use it to disable Phantom Assassin's Blur and Coup de Grace, thus taking down her attack evasion and drastically reducing her damage output.
* Because Phantom Assassin is always reliant on critical strikes, Slark will have plenty of time to escape with Pounce, Shadow Dance and Silver Edge (provided that he purchased it already).
* Essence Shift can be very harmful for Phantom Assassin as losing the agility means that her physical damage will be also reduced, which can also weaken Coup de Grace if Slark manages to steal lots of agility from her.
* Overall, any attempt for Phantom Assassin to take down Slark will hurt her more than Slark.