* Heroes with abilities or items that can silence or disable Anti-Mage for long periods of time will prevent him from Blinking away: Lion, Silencer, Shadow Shaman, Grimstroke, Witch Doctor, Riki, Faceless Void, Skywrath Mage, Puck.

* Jakiro's area-of-effect abilities make him strong against heroes who rely on illusions and summons: Terrorblade, Naga Siren Chaos Knight, Phantom Lancer, Broodmother, Nature's Prophet, Lycan, Wraith King, Visage.

* Jakiro's area-of-effect abilities make him strong against heroes who rely on illusions and summons: Terrorblade, Naga Siren Chaos Knight, Phantom Lancer, Broodmother, Nature's Prophet, Lycan, Wraith King, Visage.

* Jakiro's early pushing ability from Liquid Fire makes Jakiro very strong against heroes, that take a long time to get online: Morphling, Naga Siren, Spectre.

* Shackles prevents Chen from acting, and damages him while healing Shadow Shaman, also allowing Shadow Shaman's allies to kill him faster. Aghanim's Shard upgraded Shackles can also summon four more Mass Serpent Wards to attack Chen while he is disabled. And to make things worse, Chen has no way to cancel Shackles on his own, and must rely on outside from {U:Centaur Conqueror} or {U:Mud Golem} under his control.
* Ether Shock and Mass Serpent Ward can often not only kill Chen's allies before he can save them with Hand of God, but they can also be used to destroy Chen's creeps easily thanks to their high damage and area-of-effect.
* Hex will prevent Chen from any attempt to save himself or his allies with Hand of God.
Additional:
* Shackles prevents Chen from acting, and damages him while healing Shadow Shaman, also allowing Shadow Shaman's allies to kill him faster. Aghanim's Shard upgraded Shackles can also summon four more Mass Serpent Wards to attack Chen while he is disabled. And to make things worse, Chen has no way to cancel Shackles on his own, and must rely on {U:Centaur Conqueror} or {U:Mud Golem} creeps under his control to be able to do so.
* Ether Shock and Mass Serpent Ward can often not only kill Chen's allies before he can save them with Hand of God, but they can also be used to destroy Chen's creeps easily thanks to their high damage and area-of-effect.
* Hex will prevent Chen from any attempt to save himself or his allies with Hand of God.

* Dual Breath, Liquid Fire, Liquid Frost from Aghanim's Shard and Macropyre allows Jakiro can clear Chen's creeps, and kill his allies before he uses Hand of God.
* Macropyre can quickly clear Chen's creeps and deal intense damage to his allies, Aghanim's Scepter upgraded Macropyre can also deal pure damage to Chen and his creeps and allies and pierce spell immunity.
Additional:
* Jakiro's damage over time force Chen to use Hand of God prematurely, potentially wasting chance to save his allies during teamfight.
* Dual Breath and Macropyre can be used to disrupt Chen's jungling work.

* Shackles and Hex can both be used on Muerta while in Pierce the Veil, potentially wasting it until she gets Black King Bar.
* Ether Shock and Shackles can deal high damage to Muerta while she is affected by Pierce the Veil.
* However, Mass Serpent Ward cannot hurt Muerta while Pierce the Veil is active.

* Jakiro's abilities all deal magical damage over time, which allows him to attack Muerta even through Pierce the Veil.
* Dual Breath and Liquid Fire can be used to harass Muerta on lane.
* Ice Path can be used to stun Muerta when she uses Pierce the Veil, giving his allies time to escape or counter-initiate against Muerta.
* Aghanim's Scepter upgraded Macropyre can deal pure damage and pierce debuff immunity, rendering both, Pierce the Veil and Black King Bar useless.
* However, Jakiro is vulnerable to Muerta's The Calling as it can easily silence him due to his low mobility. In addition, Liquid Fire and Liquid Frost from Aghanim's Shard will not be able to be used on Muerta while Pierce the Veil is active unless she is near the enemy hero Jakiro targets with Liquid Fire and Liquid Frost or until Jakiro buys Revenant's Brooch.

* Shadow Shaman's Mass Serpent Ward together with Ether Shock can easily kill lots of Treants if played defensively.
* Hex and Shackles can disrupt Nature's Prophet's escape attempts with Teleportation.
Additional:
* Mass Serpent Ward can kill lots of treants if played defensively.
* Mass Serpent Ward, Hex, and Shackles can catch and kill a Nature's Prophet trying to use Teleportation.

* Jakiro's skill arsenal can ruin Nature's Prophet's gameplay: Dual Breath and Liquid Fire can clear treants from Nature's Call while simultaneously slowing Nature's Prophet, Ice Path can disrupt Nature's Prophet's escaping attempt with Teleportation, and Macropyre can easily clear treants from Nature's Call.
* Jakiro is a common Hurricane Pike wielder, which allows him to escape from Sprout.
Additional:
* Jakiro's Macropyre can help him to escape from Sprout and quickly clears Treants.
* Jakiro can disrupt Nature's Prophet's escape attempt with Sprout and Teleportation by using Ice Path.

* All of Shadow Shaman's abilities totally ruin Terrorblade: Ether Shock destroys his illusions, Hex prevents him from using Sunder or Manta Style in bad situations, Shackles not only that prevent him from using Sunder, but he has no way to cancel it and Mass Serpent Ward can help Shadow Shaman push faster than Terrorblade even in Metamorphosis.
Additional:
* Ether Shock, Mass Serpent Wards summoned from both, Mass Serpent Ward and Aghanim's Shard upgraded Shackles can do great damage to both, Terrorblade and his illusions.
* Hex prevents Terrorblade from using Sunder or Manta Style in bad situations. Hex can also destroy one of his illusions.
* Shackles can damage Terrorblade and prevent him from using his abilities and items, whether to fight, survive, or dispel it in any way while also healing Shadow Shaman in process. In addition, Terrorblade has no solutions to cancel it. Aghanim's Shard upgraded Shackles can also summon four more Mass Serpent Wards to attack Terrorblade while he is disabled.

* Jakiro's wide area-of-effect abilities allow him to clear the waves of Terrorblade's illusions and to damage real Terroblade.
* Both, Liquid Fire and Liquid Frost from Aghanim's Shard deal magical damage, which can bypass Terrorblade's high armor.
* Jakiro often buys Hurricane Pike, which combined with +275 Attack Range talent allows Jakiro to harass Terrorblade from safe distance without getting in range of Sunder and outrange Terrorblade greatly, even during Metamorphosis.
* Aghanim's Scepter upgraded Macropyre can deal huge pure damage to Terrorblade and his illusions and can hurt real Terrorblade even if he is protected by Black King Bar thanks to it's ability to pierce spell immunity when upgraded.
* Just bear in mind, however, that Jakiro's abilites are all dealing damage-over-time, so a well-timed Sunder may spell a doom for Jakiro if Terrorblade can get close to him unless Jakiro builds Black King Bar or Linken's Sphere and other items that can give him a burst damage.
Additional:
* Jakiro's wide area-of-effect abilities allow him to clear the waves of Terrorblade's illusions and to damage real Terroblade.
* Both, Liquid Fire and Liquid Frost from Aghanim's Shard deal magical damage, which can bypass Terrorblade's high armor.
* Jakiro often buys Hurricane Pike, which combined with +275 Attack Range talent allows Jakiro to harass Terrorblade from safe distance without getting in range of Sunder and outrange Terrorblade greatly, even during Metamorphosis.
* Aghanim's Scepter upgraded Macropyre can deal huge pure damage to Terrorblade and his illusions and can hurt real Terrorblade even if he is protected by Black King Bar thanks to it's ability to pierce spell immunity when upgraded.
* Just bear in mind, however, that Jakiro's abilites are all dealing damage-over-time, so a well-timed Sunder may spell a doom for Jakiro if Terrorblade can get close to him unless Jakiro builds Black King Bar or Linken's Sphere and other items that can give him a burst damage.

* Shackles and Mass Serpent Ward instantly destroy Refraction

* All of Jakiro's active skills can be targeted on an area, which is effective at forcing Templar Assassin to move should she Meld away.
* Many of Jakiro's spells utilize damage-over-time mechanics, which makes it easy to strip away layers of Refraction.

* Any hero who can counter-initiate in anticipation without getting caught in Reverse Polarity: Sven, Omniknight, Enigma, Luna, Naga Siren, Mars, Jakiro, Venomancer, Elder Titan, Faceless Void, Rubick, Keeper of the Light, Pugna, Invoker, Spectre, Alchemist, Treant Protector, Lina, Oracle, Zeus, Shadow Shaman, Phoenix, Razor, Huskar, Batrider, Kunkka, Tidehunter, Wraith King, Sand King, Medusa, Dawnbreaker.

* Jakiro's abilities deal damage over time, which can disrupt Magnus's attempts to initiate with Blink Dagger and Reverse Polarity.
* Macropyre not only disables Blink Dagger for a considerable duration, but can also destroy Trees, revealing Magnus's cover and position.

* Heroes with channeling spells because Shadow Fiend has nothing to cancel channeling outside of Requiem of Souls: Bane, Enigma, Pudge, Shadow Shaman, Dawnbreaker, Warlock, Crystal Maiden.

* Despite Jakiro's fragileness, he can easily harass Shadow Fiend with Dual Breath and Liquid Fire than Shadow Fiend can harass Jakiro with Shadowraze.
* Jakiro can easily cancel Requiem of Souls with Ice Path as Shadow Fiend is a very easy target while channeling it.
* Aghanim's Scepter upgraded Macropyre can deal pure damage-over-time and pierce spell immunity, which can discourage Shadow Fiend from even trying to initiate with Requiem of Souls.
Additional:
* Despite Jakiro's fragileness, he can easily harass Shadow Fiend with Dual Breath and Liquid Fire than Shadow Fiend can harass Jakiro with Shadowraze.
* Jakiro can easily cancel Requiem of Souls with Ice Path as Shadow Fiend is a very easy target while channeling it.
* Aghanim's Scepter upgraded Macropyre can deal pure damage-over-time and pierce spell immunity, which can discourage Shadow Fiend from even trying to initiate with Requiem of Souls.

* Shadow Shaman's long disables are effective at kiting and wasting the duration of Battle Trance.
* Mass Serpent Ward are especially effective against Troll Warlord during Battle Trance, as trapping him inside them during the duration is effectively another hard disable, as Troll cannot attack the wards or use Phase Boots to escape.

* Jakiro's reliance on his abilities can cause struggles for heroes who rely on evasion or blinds to get upper hand: Phantom Assassin, Windranger, Riki, Troll Warlord, Keeper of the Light.

* Heroes who can clear the waves of Enigma's Eidolons: Lina, Luna, Dawnbreaker, Jakiro, Shadow Shaman, Death Prophet, Keeper of the Light, Invoker, Leshrac, Puck.

* Most of the of Jakiro's damage-over-time abilities put Blink Dagger on cooldown, potentially forcing Enigma to prematurely activate Black King Bar.
* Jakiro's Dual Breath, Liquid Fire, Macropyre and Liquid Frost from Aghanim's Shard can take out Enigma's Eidolons, reduce Enigma's attack speed and put Enigma's Blink Dagger on cooldown.
* Jakiro can easily cancel Black Hole with Ice Path as Enigma is a very easy target while channeling it.
* Aghanim's Scepter upgraded Macropyre can deal pure damage-over-time and pierce spell immunity, which can discourage Enigma from even trying to initiate with Black Hole.
Additional:
* Most of the of Jakiro's damage-over-time abilities put Enigma's Blink Dagger on cooldown, potentially forcing him to prematurely activate Black King Bar.
* Jakiro's Dual Breath, Liquid Fire, Macropyre and Liquid Frost from Aghanim's Shard can take out Enigma's Eidolons, reduce Enigma's attack speed and put Enigma's Blink Dagger on cooldown.
* Jakiro can easily cancel Black Hole with Ice Path as Enigma is a very easy target while channeling it.
* Aghanim's Scepter upgraded Macropyre can deal pure damage-over-time and pierce spell immunity, which can discourage Enigma from even trying to initiate with Black Hole.

* Heroes with both illusions and summons, for Io has nothing to deal with multiple enemies at once outside from Spirits's weak area-of-effect: Beastmaster, Broodmother, Chaos Knight, Lycan, Naga Siren, Nature's Prophet, Phantom Lancer, Shadow Shaman, Terrorblade, Visage, Warlock, Wraith King.

* Jakiro's area-of-effect ability arsenal allows him to affect multiple heroes at once, giving Io difficulties in saving them as he can only heal one hero at a time with Tether.
* Ice Path can be used to cancel both, Tether and Relocate.
* Jakiro commonly buys Rod of Atos that can be used to cancel Relocate, prevent Io in escaping with Tether and make Io easy target for Ice Path and Macropyre.
Additional:
* Jakiro's area-of-effect ability arsenal allows him to affect multiple heroes at once, giving Io difficulties in saving them as he can only heal one hero at a time with Tether.
* Ice Path can be used to cancel both, Tether and Relocate.
* Jakiro commonly buys Rod of Atos that can be used to cancel Relocate, prevent Io in escaping with Tether and make Io easy target for Ice Path and Macropyre.

* Hex abilities can cancel the channelling of Fiend's Grip : Lion, Shadow Shaman, Dazzle from Aghanim's Shard with upgraded Poison Touch.

* Jakiro relies entirely on dealing damage through his area-of-effect abilities, making Enfeeble less effective against him, although it will still reduce his cast range.
* An ill-timed Nightmare can give Jakiro a good setup for all of his ablities.
* Jakiro can easily cancel Fiend's Grip with Ice Path, as Bane is very easy target while channeling it.
* Aghanim's Scepter upgraded Macropyre can deal pure damage-over-time and pierce spell immunity, which can discourage Bane from even trying to use Fiend's Grip.
Additional:
* Jakiro relies entirely on dealing damage through his area-of-effect abilities, making Enfeeble less effective against him, although it will still reduce his cast range.
* An ill-timed Nightmare can give Jakiro a good setup for all of his ablities.
* Jakiro can easily cancel Fiend's Grip with Ice Path, as Bane is very easy target while channeling it.
* Aghanim's Scepter upgraded Macropyre can deal pure damage-over-time and pierce spell immunity, which can discourage Bane from even trying to use Fiend's Grip.

* Shadow Shaman's many disables can lock down Weaver. Even with Linken's Sphere, Weaver might not be able to escape should Shadow Shaman uses Shackles quickly enough following Hex.
* Mass Serpent Wards can make short work of Weaver once he is locked down.

* Weaver has poor health, relying on Shukuchi and Time Lapse to survive, With Jakiro's considerable arsenal of stuns, Weaver cannot initiate on Jakiro without being punished heavily or even killed in return.
* While difficult, Ice Path can catch Weaver during Shukuchi, And since Shukuchi only lasts 4 seconds while Ice Path's stun lasts 3.5, the stun from Ice Path will strip him of his escape.
* Weaver has to be very careful casting Time Lapse around Jakiro, as it could very easily put him inside of a Macropyre or Ice Path.

* Batrider has poor survivablilty, relying on his mobility from Firefly to survive. Stunning him with Ice Path of Liquid Frost can easily spell his doom.
* Batrider tends to cast Flaming Lasso on the squishest or the tankiest hero. Which Jakiro is not squishy, nor his generally the tank of the team, Due to this, Jakiro can usually save allies with Ice Path and Liquid Frost, while also potentially removing an entire hero from play for a short period of time.
* Even if Batrider does cast Flaming Lasso on Jakiro, Batrider will generally drag Jakiro into a great setup for Ice Path and Macropyre.

* Jakiro's spells inflict AoE damage, meaning he can take down Phantom Lancer's illusion army very quickly.
* Bear in mind, however, that once Phantom Lancer buys Diffusal Blade which can burn Jakiro's mana, Jakiro will be vulnerable to Phantom Lancer 's counter-attacks if he runs out of mana.
Additional:
* Jakiro's AoE abilities are great against Phantom Lancer:
* Dual Breath slows down and damages Phantom Lancer and his illusions.
* Liquid Fire will not only deal AoE damage but also lowers Phantom Lancer's attack speed.
* Ice Path and Macropyre combo can easily clear all of Phantom Lancer's illusions.
* Jakiro can predict Doppelganger and Ice Path on top.

* Dual Breath and Liquid Fire reduces Tiny's already abysmal Attack Speed.
* If Tiny Tosses a hero onto Jakiro, he can react with Ice Path, and potentially Macropyre.
* Tiny's Avalanche is easily countered with Ice Path.
* As Tiny has a very high Health, Liquid Frost is particularly effective against him.

* Hex greatly reduces Timbersaw's mobility.
* The stun and damage over time from Shackles mitigates Reactive Armor's HP and armor regen.

* Jakiro's damage over time abilities can clear Naga Siren's illusions and can hurt real Naga Siren even for the duration of Song of the Siren.
* Naga Siren is not a hero that likes to go for Black King Bar, and that makes her very vulnerable to Jakiro's damage over time in every phase of the game.
Additional:
* Jakiro's damage over time abilities can clear Naga Siren's illusions and can hurt real Naga Siren even for the duration of Song of the Siren.
* Since Naga Siren is a hero who barely goes for Black King Bar, this can make her very vulnerable to Jakiro's damage over time in every phase of the game.

* With Dual Breath, Liquid Fire and Macropyre Jakiro can quickly remove all Living Armor from a target.
* Ice Path allows Jakiro to prevent Treant Protector from using Overgrowth while staying at a safe distance.

* Ice Path allows Jakiro to easily cancel Freezing Field.
* Freezing Field makes Crystal Maiden an easy target for all of his abilities without a Black King Bar.
* With the Aghanim's Scepter upgraded Macropyre, Black King Bar becomes nearly useless for Crystal Maiden, as its high pure damage over time, long duration and ability to pierce spell immunity will either force Crystal Maiden to forcefully cancel Freezing Field or even discourage her from using it at all.
Additional:
* Ice Path allows Jakiro to easily cancel Freezing Field.
* Freezing Field makes Crystal Maiden an easy target for all of Jakiro's abilities without a Black King Bar.
* Aghanim's Scepter upgraded Macropyre can deal pure damage-over-time and pierce spell immunity, making Black King Bar nearly useless for Crystal Maiden, as its high damage over time and long duration can discourage Crystal Maiden to use Freezing Field. Remember, however, that Crystal Maiden can partially solve this issue by buying Aghanim's Shard, which will allow her to simply walk out of Macropyre.

* Hex's instant cast time will force Brewmaster into the awkward situation of needing some form of spell immunity or block to prevent being immediately hex upon blinking in, or wait until Shaman has used all his crowd control before entering a fight.
* Brewmaster also has no defense against Shadow Shaman lockdowns.

* Shadow Shaman has many disables to lock down Queen of Pain, preventing her from Blinking away, even through Linken's Sphere or her spell block talent.
* Mass Serpent Ward can tear through Queen of Pain's low health pool once she's locked down by Hex & Shackles.

* Death Ward can be easily canceled by Jakiro, or even turned against him with Macropyre, due to it's attack range being smaller then Jakiro's cast range. And Crystal Maiden, his Scepter does not allow him to move while using it. Voodoo Switcheroo is even easier to land Jakiro's Macropyro/Ice Path combo. And unlike Crystal Maiden, Witch Doctor's Aghanim's Scepter upgraded Death Ward does not allow him to move while using it.
* While Maledict can be quite effective on Jakiro, along with repetitive stuns from Paralyzing Cask, it is very difficult to get a strong Maledict on him. Although Witch Doctor's Paralizying Cask, Maledict and Death Ward combo will still quickly eliminate Jakiro.
* On the other hand. Voodoo Restoration will partly protect his allies from Jakiro spells, as it heals based on their Max Health once he gets his Talent (Level 25). Before then though, it won't make a dent in the damage Jakiro deals.

* Jakiro's area of effect abilities can hit Dark Willow even while she is hidden during the Shadow Realm.
* Waiting about 2 seconds after Dark Willow casts Shadow Realm to cast Ice Path will stun her while her Shadow Realm is at it's maximum damage.
* Jakiro can stun Dark Willow when there is about 1 second left on Cursed Crown, Jakiro's Ice Path stun lasts slightly longer then Cursed Crown.

* Mana Drain can be easily canceled with Ice Path. However, Lion can counter this by buying his Aghanim's Shard though, that is no longer possible, but Jakiro can counter this too with Aghanim's Scepter upgraded Macropyre will deal pure damage through the debuff immunity forcing Lion to cancel it or die.
* Lion has very strong single target capabilities, but usually struggles against multiple heroes, while Jakiro has good multi-target capabilities, His abilities also have a much shorter cast range then Jakiro's, allowing Jakiro to cast his abilities before he can get off his Hex or Earth Spike.
* Jakiro can also save an ally who Lion is attempting to Finger of Death by casting Ice Path on Lion.

* Can easily interrupt and disable Spirit Breaker with hex if being charged.

* Heroes that can slow Charge of Darkness by a huge amount: Venomancer, Viper, Dazzle, Arc Warden, Lion, Huskar, Shadow Shaman, Visage, Undying, Jakiro.

* Hex can be used immediately to destroy Spectre's illusion when she Haunts.
* Shadow Shaman can use Shackles to lock down Spectre for his team.
* Shadow Shaman's Mass Serpent Ward and Ether Shock help him push lanes and end the game early before Spectre can come online and take over the late game.

* Jakiro's early pushing ability from Liquid Fire makes Jakiro very strong against heroes, that take a long time to get online: Morphling, Naga Siren, Spectre.

* Jakiro has 3 damage over time spells, 2 of which are from debuffs on Puck (Dual Breath and Liquid Fire) and 1 affecting an entire area (Macropyre), making it easy for him to disable the Blink Dagger.
* Ice Path is also strong against Puck, as he can cast it towards Puck during Phase Shift, who then gets instantly stunned once Phase Shift ends.
Additional:
* Jakiro has 3 damage over time spells, 3 of which are from debuffs on Puck: Dual Breath, Liquid Fire and Liquid Frost from Aghanim's Shard from and 1 affecting an entire area (Macropyre), making it easy for him to disable the blink dagger.
* Ice Path is also strong against Puck, as he can cast it towards Puck during Phase Shift, who then gets instantly stunned once Phase Shift ends.

* Both Jakiro's Ice Path and Liquid Frost can be used to cancel Life Drain from either Jakiro or an ally.
* Decrepify only makes Pugna even more vulnerable to Jakiro's magical damage, And it has no adverse effects on Jakiro himself.
* Aghanim's Scepter upgraded Macropyre can deal pure damage-over-time and pierce debuff immunity, which can discourage Pugna from even trying to use Life Drain.
* Bear in mind, however, that Nether Ward can do some considerable damage to Jakiro due to high mana costs on his abilities.

* Both Ice Path and Macropyre are the good setup against Earthshaker after he jumps in with Blink Dagger, and stay out of Echo Slam initiation radius.
* Jakiro's damage over time abilities can potentially disable Earthshaker's Blink Dagger.

* Mass Serpent Ward rips apart Huskar quickly due to his poor armor.
* As soon as Huskar jumps in, he will be vulnerable to Shadow Shaman's disables if he does not have Black King Bar.

* Heroes with illusions and summons can be hard for Phantom Assassin to deal with, as she lacks any AoE abilities to deal with them without items: Broodmother, Phantom Lancer, Chaos Knight, Lycan, Naga Siren, Shadow Shaman, Visage, Nature's Prophet, Terrorblade, Warlock, Wraith King.

* Jakiro's reliance on his abilities can cause struggles for heroes who rely on evasion or blinds to get upper hand: Phantom Assassin, Windranger, Riki, Troll Warlord, Keeper of the Light.

* A couple of nukers and disablers on the same lane can finish a squishy Luna efficiently despite a teammate's assistance: Sven + Shadow Shaman.

* Even though Luna can easily kill Jakiro in few strikes, he can also do the same to her is she is not careful.
* Dual Breath and Liquid Fire allow Jakiro to harass Luna more efficiently than she can harass Jakiro with her Lucent Beam.
* Jakiro can save his allies from Luna during her attempts to use Eclipse by casting Ice Path on Luna.
* Aghanim's Scepter upgraded Macropyre can deal pure damage-over-time and pierce spell immunity, which can make it very hard for Luna to be in teamfights without suffering too many damage.
* For the same reasons, Jakiro makes a very powerful ally for Luna when they are in the same team.
Additional:
* Even though Luna can easily kill Jakiro in few strikes, he can also do the same to her is she is not careful.
* Dual Breath and Liquid Fire allow Jakiro to harass Luna more efficiently than she can harass Jakiro with her Lucent Beam.
* Jakiro can save his allies from Luna during her attempts to use Eclipse by casting Ice Path on Luna.
* Aghanim's Scepter upgraded Macropyre can deal pure damage-over-time and pierce spell immunity, which can make it very hard for Luna to be in teamfights without suffering too many damage.
* For the same reasons, Jakiro makes a very powerful ally for Luna when they are in the same team.

* Heroes with break can disable Untouchable for a while: Doom and Shadow Demon (via Aghanim's Scepter), Viper, Shadow Shaman with Hex Breaks talent.

* Heroes with strong area-of-effect damaging and/or disabling abilities will be able to intercept Underlord and his team when they exit from Fiend's Gate: Luna's Aghanim's Scepter upgraded Eclipse, Dawnbreaker's Solar Guardian, Axe's Berserker's Call, Mars's Arena of Blood, Jakiro's Macropyre, Dual Breath and Ice Path, Naga Siren's Song of the Siren, Razor's Eye of the Storm and Plasma Field, Lina's Light Strike Array, Broodmother's Spinner's Snare from Aghanim's Scepter, Elder Titan's Earth Splitter and Echo Stomp, Alchemist's Unstable Concoction and Acid Spray, Queen of Pain's Sonic Wave, Dark Seer's Wall of Replica and Vacuum, Venomancer's Noxious Plague and Poison Nova from Aghanim's Scepter, Oracle's Fortune's End and Rain of Destiny from Aghanim's Shard, Bloodseeker's Blood Rite, Enigma's Black Hole and Midnight Pulse, Shadow Fiend's Requiem of Souls, Batrider's Aghanim's Scepter upgraded Flaming Lasso, Firefly, Flamebreak and Sticky Napalm, Ancient Apparition's Ice Blast, Sand King's Epicenter, Sand Storm and Burrowstrike, Gyrocopter's Call Down, Ember Spirit's Sleight of Fist, Death Prophet's Exorcism and Silence, Monkey King's Wukong's Command, Crystal Maiden's Freezing Field, Muerta's The Calling, Medusa's Stone Gaze, Zeus's Nimbus from Aghanim's Scepter. Dark Willow's Bramble Maze, Pangolier's Swashbuckle, Grimstroke's Soulbind, Ink Swell and Stroke of Fate, Earthshaker's Echo Slam and Fissure, Puck's Dream Coil and Waning Rift, Winter Wyvern's Winter's Curse, Magnus's Reverse Polarity.

* Viper cannot interrupt heroes with powerful channeling abilities: Bane, Enigma, Shadow Shaman, Warlock

* Heroes that can keep Marci for a long time in one place so she can't pursue her targets, like Bane, Lion, Shadow Shaman, Invoker, Disruptor and Kunkka.

Additional:
* Shadow Shaman can provide an excellent counter-initiation against her Rebound. His abilities can shut down any of her tower dive attempts in the laning phase.
* Shackles keeps Marci stunned for an extended time, wasting her ultimate. A combo with Mass Serpent Ward only makes things worse for her, as her armor is low.

* Sven is very vulnerable to chain stun such as Lion, Shadow Shaman or Magnus.

* In general, squishy heroes that rely on escape often struggle against the amount of disables Shadow Shaman can bring. Queen of Pain, Anti-Mage and Storm Spirit are among these.

* Jakiro's area-of-effect abilities make him strong against heroes who rely on illusions and summons: Terrorblade, Naga Siren Chaos Knight, Phantom Lancer, Broodmother, Nature's Prophet, Lycan, Wraith King, Visage.

* Heroes with channeling spells are very easy targets for Jakiro's abilities: Crystal Maiden, Dawnbreaker, Enigma, Pudge, Shadow Fiend, Shadow Shaman, Warlock.

* Jakiro's reliance on his abilities can cause struggles for heroes who rely on evasion or blinds to get upper hand: Phantom Assassin, Windranger, Riki, Troll Warlord, Keeper of the Light.

* Heroes with channeling spells are very easy targets for Jakiro's abilities: Crystal Maiden, Dawnbreaker, Enigma, Pudge, Shadow Fiend, Shadow Shaman, Warlock.

* Heroes with long lockdowns: Shadow Shaman, Legion Commander.

* Heroes with silence and mana drain abilites, as Ancient Apparition relies entirely on his abilities: Invoker, Silencer, Nyx Assassin, Skywrath Mage, Shadow Shaman, Lion and etc.

* With his AoE damage, Jakiro can easily kill Chaos Knight's Phantasm illusions.
* Chaos Knight usually doesn't buy a Black King Bar, making him vulnerable to an Ice Path into Macropyre combination.
Additional:
* With his AoE damage, Jakiro can easily kill Chaos Knight's Phantasm illusions.
* Chaos Knight usually doesn't buy a Black King Bar, making him vulnerable to an Ice Path into Macropyre combination.

* Broodmother and her Spiderlings need to be very careful during the laning stage against Jakiro, as Jakiro can take down Broodmother's Spiderlings, preventing her from pushing as well as gaining a good amount of gold.

* Jakiro's area-of-effect abilities that deal magical damsge make it hard for Omniknight to save multiple enemy heroes at once with Purification and Repel, and Guardian Angel and to harass Omniknight on lane.
* Aghanim's Scepter upgraded Macropyre allows Jakiro to deal pure damage and slow enemy heroes which can pierce debuff immunity, rendering both Repel and Guardian Angel useless.

* Ice Path is a great stun for Berserker's Call and with a Eul's Scepter of Divinity can really catch Axe off guard.
* Dual Breath and Liquid Fire can be a devastating combination for Axe (especially if he takes Battle Hunger at level 1) before he has any natural regeneration sustain from items.
Additional:
* Ice Path neutralizes initiation attempts with Berserker's Call, and its long area of effect discourages follow-ups from Axe's teammates until Axe buys Black King Bar.
* Ice Path serves as a large obstacle to stop Axe from chasing down fleeing stragglers to kill with Culling Blade until Axe buys Black King Bar.
* Jakiro's many damage-per-second skills prevent Axe from initiating with his Blink Dagger. Forcing Axe to buy Black King Bar prematurely to protect himself against Jakiro's abilities and counter-initiaions.

* Even though carry Silencer can easily take down a support Jakiro with his Glaives of Wisdom, Jakiro can also do the same to Silencer if he is not careful and if Jakiro is not played as support. As Silencer is rather squishy and lacks escape mechanisms without items, and Jakiro's damage over time abilities can take advantage of this.
* Ice Path can be used to prevent Silencer from escaping. And if Jakiro uses Ice Path along with Macropyre and Dual Breath in anticipation right before Silencer uses his abilities to disable Jakiro, Jakiro will be able to kill Silencer before he even gets a chance to do anything to Jakiro.
* Dual Breath, Liquid Fire and Liquid Frost from Aghanim's Shard can greatly reduce Silencer's attack speed.
* Aghanim's Scepter upgraded Macropyre can deal huge pure damage to Silencer even if Silencer is spell immune.
* Bear in mind, however, that Jakiro should approach Silencer carefully as Silencer's Arcane Curse, Last Word and Global Silence prevents Jakiro from casting any spell. Jakiro, however, can counter this by going for Guardian Greaves, a common item on support Jakiro, and with Black King Bar and Manta Style, a situational items on Jakiro.
Additional:
* Even though carry Silencer can easily take down a support Jakiro with his Glaives of Wisdom, Jakiro can also do the same to Silencer if he is not careful and if Jakiro is not played as support. As Silencer is rather squishy and lacks escape mechanisms without items, and Jakiro's damage over time abilities can take advantage of this.
* Ice Path can be used to prevent Silencer from escaping. And if Jakiro uses Ice Path along with Macropyre and Dual Breath in anticipation right before Silencer uses his abilities to disable Jakiro, Jakiro will be able to kill SIlencer before he even gets a chance to do anything to Jakiro.
* Dual Breath, Liquid Fire and Liquid Frost from Aghanim's Shard can greatly reduce Silencer's attack speed.
* Aghanim's Scepter upgraded Macropyre can deal huge pure damage to Silencer even if Silencer is spell immune.
* Bear in mind, however, that Jakiro should approach Silencer carefully as Silencer's Arcane Curse, Last Word and Global Silence prevents Jakiro from casting any spell. Jakiro, however, can counter this by going for Guardian Greaves, a common item on support Jakiro, and with Black King Bar and Manta Style, a situational items on Jakiro.

* Tinker's Laser has very little effect on Jakiro.
* Tinker has to sit still for a short period of time due to Rearm, not only making it easy to catch him with Ice Path, but also by stunning him while he is Rearming, Jakiro generally spell Tinker's doom.
* With s high area-of-effect and strong damage-over-time capabilties, Jakiro can quickly burn through his Defense Matrix, and at the same time lock down his Blink Dagger. Both of which he relies heavily to survive on.

* Jakiro's reliance on his abilities can cause struggles for heroes who rely on evasion or blinds to get upper hand: Phantom Assassin, Windranger, Riki, Troll Warlord, Keeper of the Light.

* Riki can easily be caught in an Ice Path and Macropyre combo as he finishes Tricks of the Trade, Jakiro just has to be careful about Riki's Smoke Screen when dealing with Riki.

* Heroes with AoE abilities will hit Slark in Shadow Dance: Lina, Jakiro, Underlord, Leshrac, Dark Seer, Earthshaker, Timbersaw, Crystal Maiden.

* Heroes with channeling spells are very easy targets for Jakiro's abilities: Crystal Maiden, Dawnbreaker, Enigma, Pudge, Shadow Fiend, Shadow Shaman, Warlock.

* While Jakiro's damage is going to be little more then average against him due to his Bristleback. His large quantity of stuns can prevent Bristleback from getting his much needed Warpath stacks, while also giving his allies a chance to counter his high defense.
* Dual Breath and Liquid Frost both reduce Movement Speed, removing one of Bristlebacks greatest strengths.
* Liquid Fire reduces Bristlebacks Attack Speed, making it harder for him to burst down a hero with Warpath.
* However Bristleback can generally catch and kill a lone Jakiro. And Jakiro is only effective in a group.

* Heroes with long or multiple disables will prevent Legion Commander from winning Duels: Shadow Shaman, Lion

* Heroes who rely on damage over time as Spiked Carapace can block and reflect only one instance of damage: Jakiro, Viper, Venomancer, Huskar, Ember Spirit, Dark Seer, Sand King, Doom, Dawnbreaker. However, this also means they are easily stunned.

* All of Jakiro's skills are Area of Effect, which can easily affect all Meepos in a targeted area.