* Heroes with abilities or items that can silence or disable Anti-Mage for long periods of time will prevent him from Blinking away: Lion, Silencer, Shadow Shaman, Grimstroke, Witch Doctor, Riki, Faceless Void, Skywrath Mage, Puck.

* Heroes with long or multiple disables will prevent Legion Commander from winning Duels: Shadow Shaman, Lion

* Heroes with strong area-of-effect damaging and/or disabling abilities will be able to intercept Underlord and his team when they exit from Fiend's Gate: Luna's Aghanim's Scepter upgraded Eclipse, Dawnbreaker's Solar Guardian, Axe's Berserker's Call, Mars's Arena of Blood, Jakiro's Macropyre, Dual Breath and Ice Path, Naga Siren's Song of the Siren, Razor's Eye of the Storm and Plasma Field, Lina's Light Strike Array, Broodmother's Spinner's Snare from Aghanim's Scepter, Elder Titan's Earth Splitter and Echo Stomp, Alchemist's Unstable Concoction and Acid Spray, Queen of Pain's Sonic Wave, Dark Seer's Wall of Replica and Vacuum, Venomancer's Noxious Plague and Poison Nova from Aghanim's Scepter, Oracle's Fortune's End and Rain of Destiny from Aghanim's Shard, Bloodseeker's Blood Rite, Enigma's Black Hole and Midnight Pulse, Shadow Fiend's Requiem of Souls, Batrider's Aghanim's Scepter upgraded Flaming Lasso, Firefly, Flamebreak and Sticky Napalm, Ancient Apparition's Ice Blast, Sand King's Epicenter, Sand Storm and Burrowstrike, Gyrocopter's Call Down, Ember Spirit's Sleight of Fist, Death Prophet's Exorcism and Silence, Monkey King's Wukong's Command, Crystal Maiden's Freezing Field, Muerta's The Calling, Medusa's Stone Gaze, Zeus's Nimbus from Aghanim's Scepter. Dark Willow's Bramble Maze, Pangolier's Swashbuckle, Grimstroke's Soulbind, Ink Swell and Stroke of Fate, Earthshaker's Echo Slam and Fissure, Puck's Dream Coil and Waning Rift, Winter Wyvern's Winter's Curse, Magnus's Reverse Polarity.

* Viper cannot interrupt heroes with powerful channeling abilities: Bane, Enigma, Shadow Shaman, Warlock

* A couple of nukers and disablers on the same lane can finish a squishy Luna efficiently despite a teammate's assistance: Sven + Shadow Shaman.

* In general, heroes that can slow down Dragon Knight's movement speed will do well against him. This includes Venomancer and others in addition to the heroes mentioned above.

* Shackles and Hex can both be used on Muerta while in Pierce the Veil, potentially wasting it until she gets Black King Bar.
* Ether Shock and Shackles can deal high damage to Muerta while she is affected by Pierce the Veil.
* However, Mass Serpent Ward cannot hurt Muerta while Pierce the Veil is active.

* Heroes that commonly attack ethereal units will not have any problems against Muerta's Pierce The Veil: Tinker, Jakiro, Lina, Luna, Pugna or Ogre Magi, Enigma, Batrider, Techies, Broodmother, Dawnbreaker, Shadow Shaman, Bane, Tinker, Venomancer, Arc Warden.

* Heroes with break can disable Untouchable for a while: Doom and Shadow Demon (via Aghanim's Scepter), Viper, Shadow Shaman with Hex Breaks talent.

* Untouchable won't mitigate Venomancer's magical damage, and Enchantress is vulnerable to magic damage.
* Both Venomous Gale and Poison Nova lower the amount of healing received by Enchantress and her allies from Nature's Attendants.

* Any hero who can counter-initiate in anticipation without getting caught in Reverse Polarity: Sven, Omniknight, Enigma, Luna, Naga Siren, Mars, Jakiro, Venomancer, Elder Titan, Faceless Void, Rubick, Keeper of the Light, Pugna, Invoker, Spectre, Alchemist, Treant Protector, Lina, Oracle, Zeus, Shadow Shaman, Phoenix, Razor, Huskar, Batrider, Kunkka, Tidehunter, Wraith King, Sand King, Medusa, Dawnbreaker.

* Similar to Night Stalker, Venomancer can simultaneously scout Magnus hiding in trees and put Blink Dagger on cooldown with Plague Ward, which gives Magnus problems when trying to blink in and initiate.
Additional:
* Venomancer can simultaneously scout Magnus hiding in trees and putting Blink Dagger on cooldown with Plague Wards, which makes Magnus real problems to blink and initiate.

* Shackles prevents Chen from acting, and damages him while healing Shadow Shaman, also allowing Shadow Shaman's allies to kill him faster. Aghanim's Shard upgraded Shackles can also summon four more Mass Serpent Wards to attack Chen while he is disabled. And to make things worse, Chen has no way to cancel Shackles on his own, and must rely on outside from {U:Centaur Conqueror} or {U:Mud Golem} under his control.
* Ether Shock and Mass Serpent Ward can often not only kill Chen's allies before he can save them with Hand of God, but they can also be used to destroy Chen's creeps easily thanks to their high damage and area-of-effect.
* Hex will prevent Chen from any attempt to save himself or his allies with Hand of God.
Additional:
* Shackles prevents Chen from acting, and damages him while healing Shadow Shaman, also allowing Shadow Shaman's allies to kill him faster. Aghanim's Shard upgraded Shackles can also summon four more Mass Serpent Wards to attack Chen while he is disabled. And to make things worse, Chen has no way to cancel Shackles on his own, and must rely on {U:Centaur Conqueror} or {U:Mud Golem} creeps under his control to be able to do so.
* Ether Shock and Mass Serpent Ward can often not only kill Chen's allies before he can save them with Hand of God, but they can also be used to destroy Chen's creeps easily thanks to their high damage and area-of-effect.
* Hex will prevent Chen from any attempt to save himself or his allies with Hand of God.

* Venomancer's damage over time can force Chen to use Hand of God prematurely, potentially wasting a chance to save his allies during a teamfight.
* Venomancer's Poison Nova, Venomous Gale and Plague Ward can easily kill Chen's creeps.

* Shackles and Mass Serpent Ward instantly destroy Refraction

* Venomancer's entire arsenal deals lingering damage over a long time and therefore burns through her Refraction very quickly. Not only that, his persistent slow from Poison Sting (it can be re-applied again and again with Plague Ward) allows his team to catch up to her even with the disruption from her Psionic Trap.
Additional:
* Venomous Gale and Plague Wards allow to quickly melt through Refraction charges.
* Both Poison Nova and Venomous Gale hit invisible units, so Meld cannot be used defensively.

* Hex can be used immediately to destroy Spectre's illusion when she Haunts.
* Shadow Shaman can use Shackles to lock down Spectre for his team.
* Shadow Shaman's Mass Serpent Ward and Ether Shock help him push lanes and end the game early before Spectre can come online and take over the late game.

* Venomancer's poison damage over time is very effective against Spectre, who tends to lack magic resistance during the early to mid game.
* Venomancer's multiple slows greatly reduces Spectre's movement speed and mobility.
* Plague Wards can scout out Spectre while she is hiding in trees.
Additional:
* Venomancer's poison damage-over-time are very effective against Spectre, which is lack of magic resistance from early to mid game.
* Venomancer's multiple slows greatly reduces Spectre's low mobility, even through Spectral Dagger.
* Plague Wards reveals Spectre while she is hiding on trees.

* Heroes with illusions and summons can be hard for Phantom Assassin to deal with, as she lacks any AoE abilities to deal with them without items: Broodmother, Phantom Lancer, Chaos Knight, Lycan, Naga Siren, Shadow Shaman, Visage, Nature's Prophet, Terrorblade, Warlock, Wraith King.

* Heroes that can apply early pressure before Phantom Assassin has farm are massive threats: Axe, Viper, Meepo, Jakiro, Pugna, Slark, Venomancer etc.

* Sven is very vulnerable to chain stun such as Lion, Shadow Shaman or Magnus.

* Heroes who thrive on teamfights can be a problem, such as Venomancer, Necrophos, Centaur Warrunner...

* Plague Wards are very hard for Batrider to play against as they provide a lot of vision as well as disable Blink Dagger for a long duration.

* Plague Wards may reveal a hiding Techies. If there's a sentry nearby, they may also reveal a stack of mines hidden in a juking spot.

* Venomancer's magical damage-over-time poisons will constantly put Tree Dance on cooldown, greatly diminishing Monkey King's mobility.
* Venomous Gale and Poison Nova will hit Monkey King when he is perched on a tree, or disguised with Mischief.
* However, Venomancer is also easily ganked by Monkey King if caught by surprise.
Additional:
* Venomancer's magical damage-over-time poisons putting Tree Dance on cooldown, greatly diminishing Monkey King's mobility.
* Venomous Gale and Posion Nova will hit Monkey King when he is perched on a tree, or disguised by Mischief.

* Venomancer's spells all deal magical damage, ignoring Bulwark.
* Venomancer's multiple slows are especially effective at kiting Mars.
* Plague Ward can attack through Arena Of Blood.
Additional:
* Venomancer's poison attacks are all magical damage, ignoring Bulwark.
* Venomancer's multiple slows are especially effective against Mars' low mobility.
* Plague Wards can attack through Arena of Blood.

* Unless Puck is facing the direction he wants to blink while in Phase Shift, the Venomous Gale and Noxious Plague combo consistently ticks many times over several seconds, making it very difficult to use Blink Dagger towards the other direction. Puck's slow turning rate makes this even worse.
* Venomancer can use Plague Wards to reveal Puck's position before he even gets a chance to initiate.

* Hex greatly reduces Timbersaw's mobility.
* The stun and damage over time from Shackles mitigates Reactive Armor's HP and armor regen.

* Shadow Shaman has many disables to lock down Queen of Pain, preventing her from Blinking away, even through Linken's Sphere or her spell block talent.
* Mass Serpent Ward can tear through Queen of Pain's low health pool once she's locked down by Hex & Shackles.

* Shadow Shaman's long disables are effective at kiting and wasting the duration of Battle Trance.
* Mass Serpent Ward are especially effective against Troll Warlord during Battle Trance, as trapping him inside them during the duration is effectively another hard disable, as Troll cannot attack the wards or use Phase Boots to escape.

* Can easily interrupt and disable Spirit Breaker with hex if being charged.

* Heroes that can slow Charge of Darkness by a huge amount: Venomancer, Viper, Dazzle, Arc Warden, Lion, Huskar, Shadow Shaman, Visage, Undying, Jakiro.

* Hex's instant cast time will force Brewmaster into the awkward situation of needing some form of spell immunity or block to prevent being immediately hex upon blinking in, or wait until Shaman has used all his crowd control before entering a fight.
* Brewmaster also has no defense against Shadow Shaman lockdowns.

* Shadow Shaman's many disables can lock down Weaver. Even with Linken's Sphere, Weaver might not be able to escape should Shadow Shaman uses Shackles quickly enough following Hex.
* Mass Serpent Wards can make short work of Weaver once he is locked down.

* Due to lack of magic resistance, Venomancer poisons eats through Windranger's health.
Additional:
* Due to lack of magic resistance, Venomancer abilities eats through Windranger's health.
* Venomancer's multiple slows, to an extent, negates Windrun's mobility.

* Venomancer's slows and magical damage-over-time works well against Earthshaker's which completes lack of mobility.
* Plague Wards are useful for slowing and kitting down Earthshaker, revealing him from initiating and re-initiating and putting his Blink Dagger on cooldown if Venomancer has vision over Earthshaker.
Additional:
* Earthshaker can be kited by Venomancer's slows, which is lack of mobility.
* Plague Wards is very useful for slowing and kitting down Earthshaker, revealing him from initiating and re-initiating and putting his Blink Dagger on cooldown.

* Heroes with long lockdowns: Shadow Shaman, Legion Commander.

* Heroes with channeling spells because Shadow Fiend has nothing to cancel channeling outside of Requiem of Souls: Bane, Enigma, Pudge, Shadow Shaman, Dawnbreaker, Warlock, Crystal Maiden.

* Like above, supports with reliable stuns can be a massive problem and force Black King Bar in fights unideally, such as Shadow Shaman, Lion, Nyx Assassin.

* Due to her slow movement speed,heroes with crowd control and slows can shut down Dawnbreaker:Lion, Crystal Maiden ,Venomancer etc.

* Heroes with silence and mana drain abilites, as Ancient Apparition relies entirely on his abilities: Invoker, Silencer, Nyx Assassin, Skywrath Mage, Shadow Shaman, Lion and etc.

* Heroes with both illusions and summons, for Io has nothing to deal with multiple enemies at once outside from Spirits's weak area-of-effect: Beastmaster, Broodmother, Chaos Knight, Lycan, Naga Siren, Nature's Prophet, Phantom Lancer, Shadow Shaman, Terrorblade, Visage, Warlock, Wraith King.

* Heroes that can keep Marci for a long time in one place so she can't pursue her targets, like Bane, Lion, Shadow Shaman, Invoker, Disruptor and Kunkka.

Additional:
* Shadow Shaman can provide an excellent counter-initiation against her Rebound. His abilities can shut down any of her tower dive attempts in the laning phase.
* Shackles keeps Marci stunned for an extended time, wasting her ultimate. A combo with Mass Serpent Ward only makes things worse for her, as her armor is low.

* Hex abilities can cancel the channelling of Fiend's Grip : Lion, Shadow Shaman, Dazzle from Aghanim's Shard with upgraded Poison Touch.

* Heroes who can clear the waves of Enigma's Eidolons: Lina, Luna, Dawnbreaker, Jakiro, Shadow Shaman, Death Prophet, Keeper of the Light, Invoker, Leshrac, Puck.

* All of Shadow Shaman's abilities totally ruin Terrorblade: Ether Shock destroys his illusions, Hex prevents him from using Sunder or Manta Style in bad situations, Shackles not only that prevent him from using Sunder, but he has no way to cancel it and Mass Serpent Ward can help Shadow Shaman push faster than Terrorblade even in Metamorphosis.
Additional:
* Ether Shock, Mass Serpent Wards summoned from both, Mass Serpent Ward and Aghanim's Shard upgraded Shackles can do great damage to both, Terrorblade and his illusions.
* Hex prevents Terrorblade from using Sunder or Manta Style in bad situations. Hex can also destroy one of his illusions.
* Shackles can damage Terrorblade and prevent him from using his abilities and items, whether to fight, survive, or dispel it in any way while also healing Shadow Shaman in process. In addition, Terrorblade has no solutions to cancel it. Aghanim's Shard upgraded Shackles can also summon four more Mass Serpent Wards to attack Terrorblade while he is disabled.

* Mass Serpent Ward rips apart Huskar quickly due to his poor armor.
* As soon as Huskar jumps in, he will be vulnerable to Shadow Shaman's disables if he does not have Black King Bar.

* Venomancer's magical damage-over-time poisons greatly reduce Bounty Hunter's mobility.
* Venomous Gale, combined with Plague Wards and Poison Nova with True Sight items can allow Venomancer and his teammates to gank Bounty Hunter while he is roaming alone.

* Venomancer's slows and magical damage-over-time work well against Axe's complete lack of mobility.
* Plague Ward is especially useful for slowing down Axe, and revealing him before he initiates, as well as putting his Blink Dagger on cooldown.
Additional:
* Venomancer's slows and magical damage-over-time work well against Axe's complete lack of mobility.
* Plague Wards is especially useful for slowing down Axe, and revealing him before he initiates, as well as putting his Blink Dagger on cooldown.
* For the same reasons, Venomancer is a good ally for Axe when the situation is reversed.

* Shadow Shaman's Mass Serpent Ward together with Ether Shock can easily kill lots of Treants if played defensively.
* Hex and Shackles can disrupt Nature's Prophet's escape attempts with Teleportation.
Additional:
* Mass Serpent Ward can kill lots of treants if played defensively.
* Mass Serpent Ward, Hex, and Shackles can catch and kill a Nature's Prophet trying to use Teleportation.

* In general, squishy heroes that rely on escape often struggle against the amount of disables Shadow Shaman can bring. Queen of Pain, Anti-Mage and Storm Spirit are among these.

* Heroes who rely on damage over time as Spiked Carapace can block and reflect only one instance of damage: Jakiro, Viper, Venomancer, Huskar, Ember Spirit, Dark Seer, Sand King, Doom, Dawnbreaker. However, this also means they are easily stunned.

* Aggressively Poofing and Earthbinding is not going to end well against Venomancer, as he will be an easy target for Noxious Plague.
* Venomancer's constant slows greatly reduce Meepo's mobility.

* Venomous Gale, Poison Sting and Poison Nova deal damage over time and will chip away at Gravekeeper's Cloak in addition to slowing an already sluggish hero.
* Venomancer's normal attacks deal Poison Sting and will chip away at Gravekeeper's Cloak.

* Heroes who can harass Omniknight out of lane will keep him weak in the mid game: Viper, Venomancer, Clinkz.