Sniper
* 
Assassinate is easy to reflect with Spiked Carapace for massive damage.
* 
Shrapnel's area damage can set up an easy stun with Spiked Carapace, especially when combined with Vendetta.
* In the early game, Sniper's low health pool and high intelligence makes him easy prey for Nyx Assassin.
Pugna
* Due to Pugna's incredible intelligence growth and terrible strength growth, Nyx should always be able to take you out with his combo, with or without an added 
Dagon. 
Mind Flare will deal a large amount of damage in particular, especially in the late game.
* 
Spiked Carapace is also a great tool versus Pugna. A good player will wait for you in 
Vendetta until you farm a creep wave with Nether Blast and reflect it back at you as their initiation and setup for 
Impale.
Additional:
* 
Nether Blast's animation makes it easy to time Spiked Carapace for a stun.
* Pugna has the largest intelligence gain in the game, making him a prime target for Mana Burn.
* Pugna needs to channel 
Life Drain, making him easy to hit with Impale.
Sniper
* 
Snowball allows Tusk to move himself and allies towards Sniper whilst invulnerable and hidden.
* His 
Ice Shards may also block pathing for Sniper as he has no means of moving through obstacles. In addition, 
Tag Team can hinder Sniper's escape.
Additional:
* Tusk alone or with his teammates can close Sniper's long range easily with Snowball, even wasting Shrapnel, ending with a very vulnerable Sniper.
* Walrus PUNCH! damage can easily kill Sniper instantly due to his low health.
Pugna
* Pugna's low health and reliance on channeled abilities make him very vulnerable to Tusk, although Pugna can win in a straight up 1v1 later in the game.
Sniper
* Anti-Mage can close the gap with 
Blink. Sniper will struggle to escape once he is jumped on due to the lack of mobility.
* 
Counterspell reduces sniper's magic damage from Shrapnel and Assassinate. The active component can also reflect the projectile back to sniper if he dares to target Anti-Mage.
* Counterspell active is even more dangerous if Anti-Mage purchased 
Aghanim's Scepter. Aghanims scepter allows antimage to bait out snipers range tools like pike or flashbang. Otherwise the illusion will drain his mana
* Sniper often relies on mana to use items for escaping, and his abilities cost a lot of mana. 
Mana break drains Sniper's mana and takes away Sniper's mean to disengage.
* Anti-Mage has faster farming speed. He can outfarm and get ahead of sniper easily.
Pugna
* Pugna only deals magical damage, which Anti-Mage is exceptionally resistant due to Counterspell.
* Anti-Mage can dispel 
Decrepify with 
Manta Style.
* Pugna has a very large mana pool. This allows Anti-Mage to constantly deal bonus damage to Pugna with Mana Break and devastate Pugna's entire team with Mana Void.
Additional:
* Since Pugna relies on his teammates for protection, it is fairly common for Anti-Mage to get multiple kills with a single use of his 
Mana Void on Pugna if he's missing a considerable portion of his mana.
* Pugna's massive mana pool will result in Anti-Mage's Mana Break almost always dealing the bonus damage from the mana burn.
* Counterspell negates a large amount of Pugna's damage, as most of Pugna's damage comes from his spells.
* Blink can be used to get out of a bad situation, and Pugna has no way to prevent him from casting it.
Sniper
* Fortune's End can catch out or impair position-based heroes with low mobility, such as 
Sniper or 
Razor.
Pugna
* All of Pugna's damage is magical, which can get blocked by 
Fate's Edict's 100% magic resistance.
* Oracle has two abilities that apply a dispel, which can easily remove Decrepify on his ally or Oracle.
Sniper
* Carry heroes who can close the gap reliably are very problematic: 
Phantom Lancer, 
Ember Spirit, 
Phantom Assassin.
Pugna
* Phantom Lancer creates way too many illusions for Pugna's Life Drain to destroy, overwhelming him easily.
* 
Doppelganger can dodge Nether Blast or dispel Decrepify.
* 
Diffusal Blade is a common item for Phantom Lancer to burn Pugna's large mana pool and deals a large amount of damage in the process.
Additional:
* Though Life Drain instantly destroys illusions, Phantom Lancer creates way too many for Pugna to handle.
* A good Phantom Lancer will also dodge your Nether Blast with Doppelganger.
* Phantom Lancer is the most natural Diffusal Blade carrier to burn Pugna's very large pool of mana away and deal a large amount of damage in the process.
Sniper
* Heroes who have high health are a problem for Sniper because he likes to attack the closest target and sit at the back, much like a 
Terrorblade so when that hero doesn't die; he's forced to show his position for a very long time: 
Centaur Warrunner, 
Legion Commander, 
Primal Beast.
Additional:
* Primal Beast is one of Sniper's greatest counters, as he has no real means of escape and is very squishy, especially in the early game. Sniper's potshots and Shrapnel can contribute to Primal Beast's Uproar and further make him tankier than he already is. Onslaught allows him to close the gap on Sniper at his own volition, and Trample can deal serious damage to his meager health pool. Should Sniper acquire an item of escape, Primal Beast can still delay him with Pulverize. Overall, Sniper is an ideal target for Primal Beast to constantly threaten in all stages of the game, and it can force Sniper to itemize for him.
Pugna
* Trample and Pulverize can be used to cancel Life Drain very quickly.
* Pugna has a very low strength gain and as a support does not have much gold to buy health items, making him vulnerable to Primal Beast's onslaught of magical damage.
* Ironically, Decrepify actually just increases Primal Beast's damage on the targeted ally if Trample is activated. However, it can be used to slow him down and prevent any further Trample damage.
Sniper
* Early game gankers can make life very difficult for a Sniper if he keeps being caught: 
Ursa, 
Pudge, 
Earth Spirit.
Pugna
* If Ursa uses 
Enrage, Pugna's Life Drain is next to worthless against him, due to Ursa taking 80% less damage, therefor Pugna heals by only 20% of the damage that the spell normally deals.
* It also dispels Decrepify, Even if you wait until he casted it, he can still dispel it with Shard upgraded 
Earthshock
* Ursa also commonly builds 
Skull Basher. With his high Attack Speed from 
Overpower. he can easily cancel Life Drain
* If Decrepify is defensivly casted, Ursa can still cast Earthshock both to slow you, and to deal amplified magic damage. He also commonly builds a 
Nullifier
* If Ursa jumps on you with a 
Blink Dagger he can easily wipe you out with Overpower.
* Ursa's Overpower can destroy a full health 
Nether Ward and still have a few swipes leftover, Also Ursa's low mana spells means he takes negligible damage from the Nether ward anyway.
* Ursa is also a common Diffusal Blade carrier, using it to both amplify his damage, but as his primary way to catch fleeing heroes
* Pugna is also the primary target of Ursa, due to him being both quite squishy, and a serious threat to his team, Ursa prioritizes the weakest link as 
Fury Swipes stacking damage will quickly demolish them, allowing Ursa to safely switch heroes
Sniper
* Sniper has a low health pool and strength gain, making him vulnerable to Pudge's magical and pure damage.
* Sniper usually likes to deal damage away from the fight, and Meat Hook is capable of bringing him to the front lines.
* Assassinate won't do much damage against Pudge because of his high strength gain and the strength bonuses from Flesh Heap.
* Shrapnel will be mostly blocked by Flesh Heap's active.
Additional:
* Pudge's 
Meat Hook allows him to bring Sniper in the middle of any fight, and the pure damage does well against his high armor and low health.
* 
Dismember can lock Sniper down, which makes him highly vulnerable and gives enough time for Pudge to kill him alone.
Pugna
* Heroes who build a Black King Bar (or have any sources of spell immunity) to channel abilities/items can still get interrupted by Dismember: 
Enigma, 
Juggernaut, Phantom Assassin, 
Pugna, 
Elder Titan.
Sniper
* As you can see from above, heroes who can close the gap are the biggest nightmare for the Sniper who wants to keep his distance: 
Spirit Breaker, 
Clockwerk and 
Tusk being the most classic examples because they don't require any item to do it.
Additional:
* Clockwerk is also the least optimal target for Sniper to attack in a teamfight, although more experienced players will rarely make this mistake.
* With no mobility or disable skills, getting trapped in Power Cogs is a death sentence for Sniper.
Pugna
* Clockwerk loves to 
Hookshot low health, immobile targets like Pugna.
* Pugna's Life Drain gets immediately and repeatedly (if an Aghanim's Scepter was purchased) cancelled due to 
Battery Assault, especially if Pugna is trapped inside 
Power Cogs.
* Clockwerk also loves to build 
Blade Mail, which will deal more damage to Pugna than Clockwerk due to Pugna's low health pool.
* Finally, both Hookshot and 
Rocket Flare can allow him to finish off Pugna out of range of his Nether Ward.
Additional:
* Pugna's squishiness and lack of mobility make him easy prey for a Hookshot initiation.
* Clockwerk's high health, low mana costs, and lack of reliance on Blink Dagger make Nether Ward ineffective.
* Battery Assault shuts down Aghanim's Scepter upgraded Life Drain, as the repeated ministuns prevent Pugna from channeling for an extended length of time.
Sniper
* Sniper is very squishy and cannot deal with heroes that jump onto him and lock him down. Storm Spirit closes the gap in a fight against Sniper, and Sniper has no way to escape except for some items.
* Storm Spirit can dodge Assassinate with a correctly timed 
Ball Lightning.
Additional:
* Storm Spirit can close the distance towards Sniper very easily with his ultimate Ball Lightning.
Pugna
* Pugna is a very fragile hero who can easily get caught and killed by Storm Spirit's long range initiation.
* This is especially true if he has 
Orchid Malevolence or 
Scythe of Vyse.
* Pugna has no disables that can prevent Storm Spirit from escaping.
* Even though Ball Lightning requires high amount of mana, Nether Ward is ineffective since Storm Spirit is invulnerable while using it.
* Storm Spirit's other abilities cost very insignificant amount of mana for Nether Ward to be effective.
Pugna
* Heroes with mana burn: 
Nyx Assassin, 
Invoker, 
Outworld Destroyer, Pugna, 
Lion
Sniper
* Invisible heroes all have the element of surprise. Provided they deal enough damage, Sniper should be vanquished very quickly: 
Clinkz, 
Riki, 
Bounty Hunter.
Additional:
* Sniper relies on distance. Bounty Hunter can use Shadow Walk to get close, and Jinada can do massive damage and slow down Sniper in the early game.
* Track gives additional speed to Bounty Hunter and makes 
Shadow Blade useless, which can allow Bounty Hunter to easily kill him with a few attacks.
Pugna
* Fragile heroes: Bounty Hunter has decent nuking capabilities with Shiruken Toss and Jinada thus making fragile heroes easy picks for ganking. Few examples of such heroes are:
Crystal Maiden, Pugna, 
Skywrath Mage, 
Io, 
Witch Doctor, etc.
Sniper
* Slardar can use 
Guardian Sprint with Blink Dagger or Shadow Blade to get close, and 
Slithereen Crush will stun Sniper and slow him, making him vulnerable to Slardar's teammates.
* 
Corrosive Haze lowers Sniper's armor and makes Sniper's Shadow Blade useless, easily killing him with a few attacks.
Sniper
* Sniper is completely helpless against Broodmother's abilities, and can be seriously damaged by Spiderlings in lane, especially when Shrapnel is on cooldown.
Sniper
* Ensnare with her attacks allows Naga Siren to gank Sniper easily.
* Rip Tide removes Sniper's very little armor.
Sniper
* Being mostly a physical damage dealer, Sniper's effectiveness is greatly reduced by Omniknight's 
Guardian Angel.
* Omniknight's 
Degen Aura allows him to slow sniper and catch him. Sniper has to then use some escape item.
* Omniknight can also protect an ally from being finished off by Assassinate by using 
Purification, then using 
Heavenly Grace which grants a massive strength boost.
Sniper
* 
Shukuchi allows Weaver to close the gap between himself and Sniper with high speed, and to maneuver through teamfights to get on top of him.
* A combination of 
The Swarm and 
Desolator tears through Sniper's low armor.
Sniper
* Sniper's lack of mobility and escape mechanisms makes him one of the easier heroes for Bloodseeker to gank.
Sniper
* Spirit Breaker can charge towards Sniper from anywhere on the map with 
Charge of Darkness.
* 
Greater Bash deals magical damage, which can prove dangerous to Sniper and his low health.
* Both previous abilities combined with 
Nether Strike ensures that Spirit Breaker can easily solo kill Sniper.
Sniper
* Lifestealer can close the distance to Sniper by using 
Infest on a fast or durable creep to tank Sniper's damage.
* 
Open Wounds and 
Ghoul Frenzy will reduce Sniper's mobility heavily, and 
Rage's movement speed bonus helps in closing the gap to Sniper. It also protects him from Assassinate and Shrapnel.
* Infest can dodge an incoming Assassinate.
Sniper
* Sniper has no spells to disable Puck. He lacks a silence to prevent spell casting and a stun to disable, allowing Puck to act instantly against Sniper.
* Sniper's main strategy is to attack his enemies from safe distance. Illusory Orb, combined with Blink Dagger makes it easy for Puck to get to Sniper. Due to his low health, he is also easily nuked down by Puck.
* The status debuff placed by Assassinate on its target makes it very easy to avoid it. Puck has 2 (3 when having Blink Dagger, 4 when having Eul's Scepter of Divinity, 5 when having Linken's Sphere) methods to disjoint or dodge the projectile, making it a bad spell for finishing off Puck.
Sniper
* Ember Spirit can close the distance between Sniper easily with his 
Activate Fire Remnant and further keep Sniper in place with 
Searing Chains.
* With the help of Aghanim's Scepter, Sniper cannot outrun Ember Spirit or chase him, even if Sniper builds mobility items.
Sniper
* In the mid to late game, the physical attack from Sniper can be painful to go through as 
Rubick. However with the help of Rubick's teammates, the abilities of Sniper can turn against his team.
* Shrapnel is a great wave-clear ability, and helps with scouting the area.
* Shrapnel already has a long cast range, and together with 
Arcane Supremacy Rubick can put constant damage on Sniper while he stays at back.
* Assassinate, if stolen, can be cast to assist a gank while Rubick stays at a range that can merely be found in the area, damaging heroes in the backline including Sniper.
* Arcane Supremacy (combined with Level 25 talent +40% Spell Amp For Stolen Spells, as of 7.31c) increases its damage before reduction to 406.2/611.1/819(531.2/805.1/1079) without considering any further amplification source.
* With Aghanim's Scepter, Assassinate becomes an ability with a reliable 1.5 second stun, massive damage, short cooldown and over 3000 cast range which should not be made light of.
* Shrapnel is used frequently and can be easily stolen; Assassinate has a long cast animation for Rubick to forsee the chance to steal.
Sniper
* Morphling's high mobility allows him to easily get close to Sniper, who likes to keep his distance from enemies.
Sniper
* Clinkz, Sniper, 
Lone Druid, 
Troll Warlord, Legion Commander and 
Wraith King are some of the Heroes that base themselves on attacks with little or no spell power, so they suffer in the grassy hands of Overgrowth.
Sniper
* Heroes with catch to disrupt Sniper's positioning and deliver him into the enemies: 
Batrider, 
Disruptor, Pudge, 
Vengeful Spirit.
Sniper
* Heroes with high mobility can approach Sniper: 
Anti-Mage, Earth Spirit, Io, 
Nature's Prophet, 
Pangolier, 
Puck, 
Queen of Pain and most notably Riki.
Pugna
* Pugna's Nether Ward doesn't really hurt Meepo since he usually buys attribute items to tank up and can be killed very quickly by 4 clones. Decrepify can amplify Poof's damage should Pugna use it to avoid Meepo's right clicking.
Sniper
* Invisible heroes all have the element of surprise. Provided they deal enough damage, Sniper should be vanquished very quickly: Clinkz, Riki, Bounty Hunter.
Sniper
* Heroes who have high health are a problem for Sniper because he likes to attack the closest target and sit at the back, much like a Terrorblade so when that hero doesn't die; he's forced to show his position for a very long time: Centaur Warrunner, Legion Commander, Primal Beast.
Additional:
* 
Headshot and Shrapnel slow is ineffective against a team with haste (which Stampede gives).
* Commonly picked up mobility items and hasted movement during his Stampede (as well as his high health pool) make him extremely hard to kill from a distance, damaging Sniper with Retaliate and Blade Mail if he has one.
* A low health pool and no escape mechanism makes him an easy target for Centaur Warrunner's burst damage and initiation (even making his team possible initiators with Stampede).
Sniper
* Low-health, normally mobile carries with a lot of damage are vulnerable to Bane's nukes and disables: Anti-Mage, Clinkz, 
Drow Ranger, 
Faceless Void, 
Gyrocopter, Juggernaut, 
Luna, 
Meepo, 
Mirana, 
Monkey King, 
Morphling, Phantom Assassin, Phantom Lancer, Riki, 
Shadow Fiend, 
Slark, Sniper, Terrorblade, Troll Warlord, 
Weaver.
Sniper
* Heroes with high mobility can approach Sniper: Anti-Mage, Earth Spirit, Io, Nature's Prophet, Pangolier, Puck, Queen of Pain and most notably Riki.
Sniper
* Sand King is a strong ganker, allowing him to shut down squishy heroes in the early game: Phantom Assassin, Clinkz, Sniper, 
Enchantress.
Pugna
* Heroes with no mobility will take some good damage from Sand King's spells: 
Dragon Knight, 
Jakiro, Pugna, 
Earthshaker.
Pugna
* Pugna's Nether Ward damages Sand King when he channels Epicenter, preventing him from using Blink Dagger afterward.
Pugna
* Spirit Siphon does a lot of magical damage, especially in the early game. This allows her to demolish low health heroes such as 
Zeus, Pugna, especially when combined with her other spells.
Sniper
* Heroes with high mobility can approach Sniper: Anti-Mage, Earth Spirit, Io, Nature's Prophet, Pangolier, Puck, Queen of Pain and most notably Riki.
Additional:
* Pangolier can easily get close to Sniper with Swashbuckle and Rolling Thunder, negating Sniper's range advantage.
* Lucky Shot disarms Sniper and leaves him unable to effectively fight back.
Pugna
* Heroes who rely on channeling abilities can be interrupted in teamfights by Rolling Thunder: Crystal Maiden, Pugna, Witch Doctor
Sniper
* Powerful physical hitters that can destroy Pangolier during his rolling from afar: Drow Ranger, Sniper, 
Templar Assassin, 
Arc Warden
Sniper
* Marci can be effective against vulnerable squishy heroes that cannot deal with heroes that jump onto them - Sniper, Drow Ranger, 
Lina, Rubick, etc.
Sniper
* Heroes with high mobility can approach Sniper: Anti-Mage, Earth Spirit, Io, Nature's Prophet, Pangolier, Puck, Queen of Pain and most notably Riki.
Sniper
* Other heroes that rely on physical attacks to deal damage and not their abilities: Troll Warlord, Sniper, Monkey King, 
Sven.
Sniper
* Heroes with catch to disrupt Sniper's positioning and deliver him into the enemies: Batrider, Disruptor, Pudge, Vengeful Spirit.
Sniper
* 
Stifling Dagger and 
Phantom Strike allow Phantom Assassin to close the gap with Sniper and prevent his escape.
* 
Blur allows Phantom Assassin to approach Sniper while invisible and dodge much of Sniper's damage. It can also disjoint Assassinate.
* 
Coup de Grace quickly cuts through Sniper's low health; one or two procs will usually kill him.
Additional:
* Sniper's lack of mobility and reliance on attack range makes him an easy target for Phantom Assassin to jump on.
Pugna
* Heroes that can apply early pressure before Phantom Assassin has farm are massive threats: 
Axe, 
Viper, Meepo, Pugna, Slark etc.
Pugna
* Both Jakiro's Ice Path and Liquid Frost can be used to cancel Life Drain from either Jakiro or an ally.
* Decrepify only makes Pugna even more vulnerable to Jakiro's magical damage, And it has no adverse effects on Jakiro himself.
* Aghanim's Scepter upgraded 
Macropyre can deal pure damage-over-time and pierce debuff immunity, which can discourage Pugna from even trying to use Life Drain.
* Bear in mind, however, that Nether Ward can do some considerable damage to Jakiro due to high mana costs on his abilities.
Sniper
* Heroes with good counter-push abilities to clear creep waves can hinder Jakiro's early pushing ability: 
Death Prophet, Sniper, 
Tinker, 
Windranger.
Sniper
* Sniper has no natural escape and relies on his range and slows to keep himself safe, which Riki can bypass with Blink Strike and quickly deplete his miniature HP pool.
Pugna
* Heroes who are reliant on physical damage will be nullified by Decrepify: Riki, Wraith King, Juggernaut.
Sniper
* Sniper's 
Take Aim can be wasted with either Muerta's 
Pierce the Veil or a well aimed 
Dead Shot.
* Dead Shot can displace Sniper from safe spots into the offensive range of Muerta's team, leading to potential kills on Sniper.
* Sniper relies heavily on his basic attacks, which is useless against Pierce the Veil.
Pugna
* Heroes that commonly attack etheral units do not have any problems against Muerta (such as Tinker, Jakiro, Luna, Pugna or 
Ogre Magi)
Pugna
* Luna can deal constant damage to Pugna through the low-cooldown Lucent Beam and her right clicks.
* Life Drain will be always canceled by 
Lucent Beam if Pugna does not have 
Black King Bar.
* Decrepify can be suicide against Luna due to Lucent Beam and 
Eclipse.
* Nether Ward is rather weak against Luna because unlike other heroes who rely on magical damage to damage or kill enemies, yet have very high mana costs, she does not have abilities that cost a lot of mana and Luna mostly uses her abilities to initiate a teamfight or to finish off fleeing enemy heroes.
* Luna is a common Black King Bar carrier, which allows her to protect herself against Pugna's only-magical damage output.
Additional:
* Luna can deal constant damage to Pugna through the low-cooldown Lucent Beam and her right clicks.
* Life Drain will be always canceled by Lucent Beam if Pugna does not have Black King Bar.
* Decrepify can be suicide against Luna due to Lucent Beam and Eclipse.
* Nether Ward is rather weak against Luna because unlike other heroes who rely on magical damage to damage or kill enemies, yet their ablities have very high mana costs, Luna does not have abilities that cost a lot of mana and Luna mostly uses her abilities to initiate a teamfight or to finish off fleeing enemy heroes.
* Luna is a common Black King Bar carrier, which allows her to protect herself against Pugna's only-magical damage output.
Sniper
* Heroes that outrange Luna can be a problem for her: Drow Ranger, Sniper.
Sniper
* Sniper lacks any protection against Lion's disables early in the game.
* Lion's 
Earth Spike and 
Finger of Death may roughly hit Sniper at the latter increased attack range, making it possible to gank and to disable him from afar in clashes.
* Finger of Death is incredibly dangerous for Sniper as it may shred him away from fights, or in the worst scenario, cause his death.
Pugna
* Nether Ward will be problematic for heavy nukers and spammers like Skywrath Mage, Lina, Lion and Invoker, but Pugna must not use Decrepify defensively against them as he will be helping them out more than anything.
Sniper
* Take Aim extends Sniper's attack range, allowing him to position himself safely behind his team, making it difficult to catch him in Enigma's relatively small area-of-effect for 
Black Hole. When left unattended, he can quickly kill a channeling Enigma (often from the high ground) to rout an otherwise strong initiation.
* In the early game, Sniper can cancel Enigma's Black Hole with Assassinate's ministun. Due to the absolutely ginormous 3000 cast range on Assassinate, Sniper does not need to be too close to Enigma to cancel his Black Hole. Aghanim's Scepter upgraded Assassinate can also stun Enigma for a longer duration.
* Both Shrapnel and Assassinate put Enigma's Blink Dagger on cooldown, potentially forcing him to prematurely activate Black King Bar.
Additional:
* Sniper has a very long range, so it is rare that Enigma can catch him in a Black Hole.
* Assassinate can easily cancel Black Hole if he is not caught, especially with Aghanim's Scepter.
* Enigma's Eidolons from 
Demonic Conversion are useless to push against a Sniper as he will easily kill them, especially with 
Maelstrom/
Mjollnir.
Pugna
* Enigma's abilities have a huge mana cost, meaning that Nether Ward will deal a lot of damage to Enigma.
* Pugna can heal allies trapped inside Black Hole thanks to Life Drain, Pugna can also damage multiple of Enigma's allies around him with Life Drain when he casts it on 
Aghanim's Shard upgraded Nether Ward during teamfight.
* Nether Blast can easily kill Eidolons, especially when Enigma is pushing.
* Even though Pugna cannot cancel Black Hole on his own, smart Pugna can buy Orchid Malevolence to stop Enigma from channeling Black Hole and make him more vulnerable to counter-attacks with Decrepify and Life Drain.
Additional:
* Enigma's abilities have a huge mana cost, meaning that Nether Ward will deal a lot of damage to Enigma.
* Pugna can heal allies trapped inside Black Hole thanks to Life Drain.
* Nether Blast can easily kill Eidolons, especially when Enigma is pushing.
Sniper
* Juggernaut deals most of his damage in the melee range and has no gap-closer. Sniper can easily harrass Juggernaut from afar with his long-ranged attacks and {Ability ID:Headshot|Sniper|16px} procs.Should Juggernaut decide to advance,Sniper has enough time to react and back off.
* Sniper's long range attack can destroy 
Healing Ward from a safe range, preventing any healing done to Juggernaut and/or his teammates.
* However, if Sniper is badly positioned, Juggernaut can easily terminate him.
Pugna
* Decrepify prevents 
Omnislash damage, until Juggernaut gets a Nullifier.
* Without a disable, Pugna's high movement speed makes it harder to chase him with 
Blade Fury.
* Juggernaut has low mana and his skills cost large amount of mana. Nether Ward will hurt him more and even worse, the damage from the ward is inflicted before the Spell immunity provided by Blade Fury.
Additional:
* Decrepify is the perfect tool against Omnislash until he gets a Nullifier, and even then he will probably waste a couple of slashes before he uses it.
* Without an extra disable, Pugna's high movement speed makes it impossible to chase him with Blade Fury.
* Unlike some other carries like Slark or Phantom Assassin, Juggernaut's spells cost a hefty amount of mana and he will seriously get hurt by Nether Ward. Don't forget the damage from the ward is inflicted before the spell immunity is provided by Blade Fury.
Sniper
* Shrapnel can be used to cancel Shadow Fiend's Blink Dagger from a huge range.
* Take Aim and Headshot allow Sniper to harass Shadow Fiend in lane without getting into the range of his Shadowrazes.
Additional:
* Shrapnel can be used to cancel Shadow Fiend's Blink Dagger from a huge range.
* Take Aim and Headshot allow Sniper to harass Shadow Fiend in lane without getting into the range of his 
Shadowraze.
* Assassinate when upgraded with Aghanim's Scepter can be used to cancel Shadow Fiend's 
Requiem of Souls.
Pugna
* Decrepify prevents Shadow Fiend from attacking for its duration, potentially preventing him from getting a kill.
* Nether Ward can do heavy damage to Shadow Fiend if he tries to cast his Requiem of Souls or spam Shadowraze.
Additional:
* Decrepify prevents Shadow Fiend from attacking for its duration, potentially preventing him from getting a kill.
* Nether Ward can do heavy damage to Shadow Fiend if he tries to cast his Requiem of Souls and his Shadowraze.
Sniper
* Sniper can easily destroy 
Plague Ward from long range.
Pugna
* Any hero that can outrange Plague Ward can neutralize them without putting themselves at risk of receiving Poison Sting: Arc Warden, 
Chen, Clinkz, Drow Ranger, Lina, Mirana, Nature's Prophet, Pugna and Sniper.
* Special mention to heroes that outrange Plague Ward after obtaining talents that increase attack range.
Sniper
* Melee heroes who may struggle to get close to Sniper: Wraith King, 
Kunkka, 
Doom, 
Tidehunter, 
Underlord, Troll Warlord, and etc.
Additional:
* Shrapnel and Headshot allows Sniper to kite Troll Warlord effectively.
* Take Aim together with certain items such as 
Hurricane Pike allow Sniper to sit and fire at Troll Warlord from a safe distance.
Pugna
* Troll Warlord can't switch targets at will, in order to build 
Fervor stacks, which makes it easy to use Decrepify in order to save allies
* During 
Battle Trance, Pugna can easily use Nether Blast, Decrepify and Life Drain on him
Sniper
* As Outworld Destroyer has short cast ranges, a short attack range, and no gap-closing abilities, Sniper can kite and harass Outworld Destroyer in lane with his long range and zone him out in fights. The continuous area damage from Shrapnel also prevents Astral-Blink escapes.
* However, in the late game, Outworld Destroyer's massive damage can overwhelm Sniper once he obtains Blink Dagger, 
Force Staff etc. to close the gap.
Pugna
* Any heroes with high intelligence, such as Invoker and Pugna.
Sniper
* Heroes that can easily bypass Chen's creeps to get to Chen: Riki, Tusk, Clinkz, Sniper, Slark, Phantom Assassin, 
Void Spirit, 
Storm Spirit, Ember Spirit, Earth Spirit, Spirit Breaker.
Pugna
* Nether Blast can deal high damage to Chen and clear waves of his creeps.
* Decrepify can be used to waste the duration of 
Penitence.
* Nether Ward can discourage Chen from using Penitence, 
Holy Persuasion and 
Hand of God due to their fairly high mana costs.
* Life Drain can often kill Chen or any of his allies before he can save them with Hand of God thanks to it's high damage and low cooldown.
Sniper
* Heroes with catch to disrupt Sniper's positioning and deliver him into the enemies: Batrider, Disruptor, Pudge, Vengeful Spirit.
Sniper
* Sniper can kill Disruptor while he is trapped by Kinetic Field from a long range.
* Sniper generally stays in the back, making it hard for Disruptor to cast any of his skills on him in lane.
Pugna
* Nether Ward can do a ton of damage to Disruptor because of his high mana costs.
* Life Drain can be used to heal an ally trapped by Static Storm-Kinetic Field combo (if Pugna is not a target).
Sniper
* Melee heroes who may struggle to get close to Sniper: Wraith King, Kunkka, Doom, Tidehunter, Underlord, Troll Warlord, and etc.
Pugna
* Heroes who are reliant on physical damage will be nullified by Decrepify: Riki, Wraith King, Juggernaut.
Pugna
* Nether Ward can punish Timbersaw, as Timbersaw is a spell-caster with low cooldowns. Furthermore, Timbersaw usually appears in the midst of battle, placing himself in range of Nether Ward's Mana Flares.
* Timbersaw has no stuns or silences to stop Life Drain. Since all of Pugna's Spells are magical, the damage can be devastating to Timbersaw.
* Decrepify can further increase all the magical damage done to Timbersaw, bypassing the enhanced physical resistance he can get from 
Reactive Armor.
Additional:
* Nether Ward can punish Timbersaw, as Timbersaw is a spell-caster with low cooldowns. Furthermore, Timbersaw usually appears in the midst of battle, placing himself in range of Nether Ward's Mana Flares.
* Timbersaw has no stuns or silences to stop Life Drain. Since all of Pugna's Spells are magical, the damage can be devastating to Timbersaw, especially when combined with Decrepify
Sniper
* Medusa is a fairly immobile hero that deals damage around her with 
Split Shot. Sniper should outrange her and should stay out of harm's way from Split Shot.
* More importantly, Sniper should have enough attack range to fire at Medusa during her 
Stone Gaze without turning to stone, so the ultimate is mostly wasted against him.
Additional:
* Sniper can outrange both Medusa's arrows and Stone Gaze, allowing him to focus her down during a teamfight.
Sniper
* Squishy core heroes (Shadow Fiend, Sniper, etc)
Sniper
* Shrapnel can sometimes scout out Magnus and also place his Blink Dagger on cooldown. Aside from that, Sniper likes to stay far back behind enemy lines, so it's difficult to catch him with Reverse Polarity unless you already have vision on him and can Skewer him to the rest of his team.
Pugna
* Any hero who can counter-initiate in anticipation without getting caught in Reverse Polarity: Sven, 
Omniknight, Enigma, Luna, 
Naga Siren, 
Mars, Jakiro, 
Venomancer, Elder Titan, Faceless Void, Rubick, 
Keeper of the Light, Pugna, Invoker, 
Spectre, 
Alchemist, 
Treant Protector, Lina, 
Oracle, Zeus, 
Shadow Shaman, 
Phoenix, Razor, 
Huskar, Batrider, Kunkka, Tidehunter, Wraith King, 
Sand King, 
Medusa, 
Dawnbreaker.
Sniper
* His increased attack range makes it very hard to get close enough for Static Link, Eye of the Storm and Razor's own attacks.
* Headshot procs will slow Razor heavily regardless of Storm Surge, as it will knock him back for a brief duration.
Pugna
* Leshrac needs to be close to target in order to do damage, Pugna can outrun Leshrac with ease due to his superior movement speed.
* 
Split Earth can also be hard to land on Pugna for the same reason.
* Leshrac uses huge amounts of mana to do damage, Nether Ward forces him to either not contribute in a fight or kill himself in the process.
Additional:
* Nether Ward punishes Leshrac's constant mana usage from spamming spells.
* Leshrac needs to be in the thick of the fight to deal damage, and so cannot escape from Nether Blast nor Life Drain easily.
Pugna
* Cold Embrace is a death sentence against Pugna, since its the perfect setup for all his abilities, especially Life Drain.
* Decrepify can be cast to save the ally under Winter's Curse effect, wasting most of its duration.
* Winter Wyvern's abilities require a lot of mana, allowing Nether Ward to deal lots of damage.
Sniper
* Frail heroes who lack mobility can also be an easy target to lock down with Chronosphere, such as Drow Ranger, Luna, Sniper, Terrorblade.
Sniper
* Heroes that can easily kill Faceless Void from outside his Cronosphere; Sniper, Skywrath Mage, etc.
Pugna
* Decrepify prevents Faceless Void from attacking trapped allies inside 
Chronosphere, wasting a large portion of its duration if Faceless Void can't dispel it.
Sniper
* Sniper's position in the far back line makes him unlikely to be hit by any of Grimstroke's abilities during teamfights.
* Sniper is relatively unaffected by the silence from Phantom's Embrace.
* Sniper's long range and fast projectile speed allows him quickly to destroy any Phantoms attacking his allies.
Pugna
* Due to the high mana cost of his spells and the low cool down of them, Nether Ward can seriously damage Skywrath Mage if he isn't careful.
* Skywrath Mage's fragility makes him very susceptible to Pugna's high burst damage.
Additional:
* Nether Ward will make Skywrath Mage next to useless in fights, as his low hp pool will not allow him to sustain through the damage of the ward should he choose to cast spells. Be wary though that Skywrath's huge burst will make very quick work of Pugna's low hp should the ward be destroyed, and Decrepify won't help Pugna at all.
Pugna
* Nether Ward causes Death Pulse to actually damage Necrophos rather than heal him. Meanwhile, Reaper Scythe's gigantic mana cost while Necrophos is near the Nether Ward can often instantly kill him.
* Nether Blast and Life Drain both make quick work of Necrophos's small healthpool, especially during Ghost Shroud. The latter also makes him an unappealing target for Reaper's Scythe, and can often force Necrophos to use it defensively as he has no other means of interrupting his channeling.
Sniper
* A Sniper who is somewhat competent at positioning is hardly going to be affected by any of Dark Seer's spells thanks to Take Aim.
* However, an illusion of Sniper made with Wall of Replica is extremely powerful, and hard to deal with.
Sniper
* Sniper can easily destroy 
Mass Serpent Ward from long range
Sniper
* Sniper can easily destroy 
Tombstone from long range.
Pugna
* Even though Pugna's low HP means that he can be quickly burst down, his Nether Ward heavily punishes casters whose spells cost a lot of mana, like Zeus. Casting 4 of his active spells, including Nimbus, close to an enhanced level 4 Nether Ward, can make the ward deal up to 1750 magical damage.
* Decrepify can further increase the damage dealt by Nether Ward upon Zeus. However, if used on Pugna himself or on one of his allies, it will amplify the damage done by Zeus' abilities.
Pugna
* Nether Ward discourages Tinker from using abilities and items due to its high damage against heavy mana usage.
Sniper
* With his Take Aim, Sniper can simply sit out of your ability range and deal massive damage if not killed first.
* Assassinate can target allies who are still alive with low health because of Ghostship's buff.
* Headshot makes it harder for Kunkka to position/escape and makes it hard for Kunkka to hit with Tidebringer.
Pugna
* Heroes with high movement speeds like Pugna and Meepo can run around, to, or away from Snapfire during 
Mortimer Kisses and dodge the projectiles easily due to their slow speed.
* Heroes with mobility spells (such as Queen of Pain's 
Blink and Clockwerk with Hookshot) can easily avoid 
Lil' Shredder and Mortimer Kisses.
* Heroes with high movement speeds like Pugna and Meepo can run around, to, or away from Snapfire during Mortimer Kisses and dodge the projectiles easily due to their slow speed.
Sniper
* Long ranged heroes like Sniper or Drow Ranger can kite Tiny effectively if he doesn't get the jump on them first.
Sniper
* Melee heroes who may struggle to get close to Sniper: Wraith King, Kunkka, Doom, Tidehunter, Underlord, Troll Warlord, and etc.
Additional:
* Due to the nature of the hero, Sniper is typically situated in the back of the fight, potentially making him a difficult target to initiate on and fight.
* Sniper is largely a right-click hero, and as such isn't as an effective of a Doom target as other heroes.
* Thanks to Shrapnel and Headshot, Sniper is able to effectively 'kite' Doom, preventing him from closing the distance between the two.
Sniper
* Heroes with channeled abilities which Assassinate may cancel at long range: Witch Doctor, Crystal Maiden, Shadow Shaman, Pugna
Sniper
* Heroes that can maintain vision on Monkey King can see when he uses Tree Dance: 
Bloodseeker, Treant Protector with Eyes In The Forest, Sniper, Weaver
Sniper
* Heroes who have high health are a problem for Sniper because he likes to attack the closest target and sit at the back, much like a Terrorblade so when that hero doesn't die; he's forced to show his position for a very long time: Centaur Warrunner, Legion Commander, Primal Beast.
Additional:
* Sunder can save himself or his allies from Assassinate.
* Sniper relies on right-clicks to deal damage in the late game, and Terrorblade's high armor can reduce his damage significantly.
* Terrorblade is a far harder carry than Sniper is, so a well-farmed Terrorblade can easily defeat a Sniper.
Sniper
* Unlike with other heroes who can summon illusions of themselves, Terrorblade's illusions from 
Conjure Image have different colors than other illusions which can be seen even by enemy team, which can also make Terrorblade weak even against heroes he naturally counters: 
Bane, 
Lifestealer, Spectre, 
Chaos Knight, Spirit Breaker, Sniper. Terrorblade's only solution to counter this problem is to get Manta Style as quickly as possible.
Pugna
* As Terrorblade's damage output comes mainly from direct attacks, he will struggle greatly against heroes who have abilities that give evasion, trigger on attack or which can disarm an enemy hero: Centaur Warrunner, 
Hoodwink, Huskar, Invoker, 
Leshrac with 
Nihilism from Aghanim's Scepter, Lifestealer with Aghanim's Scepter upgraded Infest, Pangolier, Phantom Assassin, Pugna, 
Techies, Windranger etc.
Sniper
* Heroes who outrange Drow Ranger such as Sniper, Tinker.
Sniper
* Melee heroes who may struggle to get close to Sniper: Wraith King, Kunkka, Doom, Tidehunter, Underlord, Troll Warlord, and etc.
Pugna
* Nether Ward will be problematic for heavy nukers and spammers like Skywrath Mage, Lina, Lion and Invoker, but Pugna must not use Decrepify defensively against them as he will be helping them out more than anything.
Sniper
* Melee heroes who may struggle to get close to Sniper: Wraith King, Kunkka, Doom, Tidehunter, Underlord, Troll Warlord, and etc.
Additional:
* Sniper's very long range allows him to stay out of Firestorm and Pit of Malice as well as Atrophy Aura range.
Sniper
* Axe can easily close the distance to Sniper with Blink Dagger.
* With 
Berserker's Call in combination with 
Counter Helix and 
Battle Hunger, Axe can make short work of Sniper, finishing him off easily with 
Culling Blade due to his low HP & high attack speed in the late game.
Sniper
* Ranged heroes that can easily harass Axe: Drow Ranger, Sniper, Lion.
Pugna
* Decrepify can be used on allies to prevent them from attacking Axe and triggering Counter Helix during Berserker's Call. He can also cast it on Axe to prevent anyone from attacking him.
* Life Drain can be used to heal himself or allies caught in Berserker's Call, preventing them from dropping low enough for Axe to kill them with Culling Blade.
Pugna
* Pugna's Decrepify makes sure that either Alchemist is unable to hit anyone while also being slowed and susceptible to magical damage, or can protect an ally from physical attacks. Besides, Pugna can push early on, when Alchemist is not strong enough to repel it, so by the time Alchemist comes online, he might be forced to sit in base.
Sniper
* Heroes with channeled abilities which Assassinate may cancel at long range: Witch Doctor, Crystal Maiden, Shadow Shaman, Pugna
Sniper
* Past the early game, Sniper is an easy target for Sven to jump on with Aghanim's Scepter or Blink Dagger.
* Sven's high armour and health pool makes it difficult for Sniper to focus, as his main source of damage is his right click.
* Sniper is very squishy, and will not stand a chance against Sven head on.
Sniper
* Special mention to Sven as he may not be able to get close, but if he does, 
God's Strength will make very short work of Sniper.
Pugna
* Pugna can save allies with both healing or by making them ethereal but needs to be careful of Sven's Aghanim's Scepter purge.
Pugna
* Heroes that can punish aggressive heroes, such as: Leshrac, 
Shadow Demon, Pugna, Death Prophet.
Sniper
* Heroes with long ranged attacks or abilities can harass Visage from afar like Phoenix and Sniper.
Pugna
* Pugna: Decrepify prevent the Spirit bear from attacking or protect allies from it.
Sniper
* Range-reliant heroes: Sniper, Drow Ranger
Pugna
* Amazingly, Enchantress has even lower health than Pugna. Though she does pack quite a punch through 
Impetus, she can't use it if she is under Decrepify.
* Pugna's Magical DPS is way greater than the heal from 
Nature's Attendants, which will also harm her quite a bit if she's next to Nether Ward.
Sniper
* Heroes with powerful nuke can waste their precious abilites on her Refraction during a ganking attempt or chaos combat: 
Lich, Lina, Sniper, Outworld Destroyer Zeus
Pugna
* Pugna's Decrepify can render Templar Assassin's physical attacks useless.
* Pugna can also cast Life Drain on Templar Assassin, burning her Refraction instances.
* On the other hand, Pugna generally has low health and armor. Use this to your advantage.
Sniper
* Heroes with high physical damage output but lack of reliable escape mechanisms are always a good target for a solo gank: Sniper, Shadow Fiend, Troll Warlord, Drow Ranger. Those heroes, however, are dangerous if they manage to close the gap, so take caution.
Pugna
* All of Pugna's abilities are active, making Demonic Purge break from Aghanim's Scepter useless.
* Nether Ward punishes Shadow Demon's constant mana usage from spamming spells, especially Shadow Poison.
* An attempt to save an ally using Disruption can easily become a perfect setup for a Nether Blast for the enemy.
* Life Drain can be used to heal Pugna or an ally to save them from Shadow Demon's abilities.
* However, it can be cancelled by Disruption unless Pugna buys defensive items.
Sniper
* Heroes who have high health are a problem for Sniper because he likes to attack the closest target and sit at the back, much like a Terrorblade so when that hero doesn't die; he's forced to show his position for a very long time: Centaur Warrunner, Legion Commander, Primal Beast.
Additional:
* Sniper's low mobility and lack of defensive abilities make him an easy gank target for the entire game, especially if Blink Dagger is picked up.
Pugna
* Decrepify prevents Legion Commander from attacking allies during 
Duel, regardless if it's used on her or on the ally .
* Pugna can easily cast Decrepify, Nether Blast and Life Drain on Legion during the 4/4.75/5.5/8 seconds of duel
Additional:
* Decrepify on either hero stops Legion Commander from completing a Duel, and dissuades her from initiating Duels on ethereal allies.
* Life Drain can help Pugna's teammates win a fight, either by killing Legion Commander or replenishing her target's health.
Pugna
* Heroes with channeled abilities can be interrupted by a long-range Fissure: Crystal Maiden, Witch Doctor, Bane, Pugna, Pudge.
Sniper
* Shrapnel can be used to disable Earthshaker's Blink Dagger from long range.
* Take Aim allows Sniper to harass Earthshaker in lane, and stay out of Echo Slam initiation radius.
Additional:
* Sniper is able to kite Earthshaker with his very long range.
* Sniper can dodge Earthshaker's stuns like 
Fissure and 
Enchant Totem with mobility items such as Blink Dagger, Force Staff/Hurricane Pike and Shadow Blade/
Silver Edge.
* Sharpnel can be used to cancel Earthshaker's Blink Dagger and preventing effective use of his 
Echo Slam in a majority of situations.
Sniper
* Heroes with high mobility can approach Sniper: Anti-Mage, Earth Spirit, Io, Nature's Prophet, Pangolier, Puck, Queen of Pain and most notably Riki.
Sniper
* Take Aim and Assassinate allow Sniper to reach Io even if it stays in the backline.
Sniper
* Even if he can slow Mars down with Shrapnel and Headshot, Mars can tank Sniper's physical damage simply by facing him with Bulwark, allowing him to endure his auto-attacks into the late-game. Should Sniper choose to attack someone else, Mars can redirect his projectiles with Bulwark's active ability.
* Sniper's poor mobility makes him very vulnerable to Arena of Blood, especially in the early game. Mars can also take advantage of this by pushing him closer to the front line with Spear of Mars.
Pugna
* Nether Blast, Decrepify and Life Drain deal high magical damage and bypasses Bulwark.
* Nether Ward reduces the amount of abilities Mars can use during fights and forces Mars to be careful about the heavy mana cost of Arena Of Blood.
* Pugna is one of few heroes that can contest Mars' ability to push and defend towers early on.
Sniper
* Sniper hugely lacks mobility and escape abilities so that he is an easy target for ganks from Slark.
Pugna
* Nether Blast will still hit Slark even if he is hidden during Shadow Dance.
* Even though Pugna can rarely target Slark directly with Decrepify, he can still use it defensively on an ally to prevent Slark from getting stacks.
* Despite being somewhat easy to break with Pounce, Pugna can damage Slark and provide vision over him with Life Drain.
Pugna
* Pugna is very reliant on his abilities for damage which Silencer can take advantage off. But he has to be careful around the Nether Ward as Silencer's abilities cost a lot of mana to use.
Sniper
* Sniper is a pure right click carry with a very long range, making it hard for Silencer to cast any of his skills on him in lane. During team-fights, 
Global Silence has little impact on Sniper.
Additional:
* Due to Sniper having a such a long range, he will rarely get hit by any of Silencer's spells.
* Global Silence will not hinder Sniper much as other heroes since most of his damage output comes from his attacks.
Sniper
* 
Haunt instantly allows her to get up and close with Sniper, and 
Spectral Dagger makes it difficult to escape from her.
Additional:
* Spectre can reach him easily in the backlines with Spectral Dagger or teleport to him with Haunt.
* He is usually a fair distance away from his allies, so 
Desolate will quickly tear Sniper down.
* 
Dispersion reflect or reduce his damage, making her hard to take down even at late game.
Pugna
* Nether Blast is one of the best tower pushing abilities in the game, with a low cooldown. A competent Pugna will (at the very least) destroy tier 2 towers and make space for his team before Spectre can finally come online.
* Spectre's spells, while not spammable, have a fairly high mana cost, so Nether Ward can be fairly damaging to Spectre early game. The mana degen will also dampen Spectre's early game power significantly.
* Once Pugna gets Aghanim's Scepter, he can spam Life Drain on any illusion Spectre summons, whether it'd be from Haunt, Manta Style, or some other means.
* In addition, Pugna can disable Spectre's Desolate ability (although its damage is pure, it requires physical attacks) with his Decrepify ability, leaving Spectre only with Spectral Dagger.
Sniper
* 
Nethertoxin breaks Sniper's passives.
* 
Corrosive Skin allows Viper to deal more damage to Sniper than Sniper deals to him when laning, especially by briefly stepping into Shrapnel.
* 
Viper Strike together with 
Poison Attack can slow Sniper and tears through his low health and mobility.
Pugna
* Pugna's Decrepify allows him to save allies from being ganked by Viper, since Viper mostly relies on direct attacks in order to deal damage.
* Nether Ward can discourage Viper from spamming his abilities.
* Viper's damage over time is not enough to kill Pugna as he will have more than enough time to save himself (or his allies) with Life Drain and Viper has no solutions to cancel it.
* Pugna has no passive abilities, which renders Nethertoxin nearly useless.
Sniper
* Magnetic Field's evasion completely negates Sniper's attacks unless he has True Strike.
* Sniper always positions himself far away from battles, which makes him especially vulnerable for Flux and Spark Wraith.
Pugna
* Arc Warden can't use Magnetic Field to stall the damage of Nether Blast on towers, but he can buy Aghanim's Shard to diminish its damage.
* Arc Warden has no innate disables to stop Life Drain and Decrepify
* The short cooldown of both Life Drain and Decrepify also means Pugna can deal with Arc Warden and Arc Warden's clone simultaneously most of the time
* A good Pugna looks to end the match early while Arc Warden, a very item reliant hero, thrives in longer matches.
Sniper
* You can easily kill a squishy Sniper, due to your high movement speed and his lack of escape.
Pugna
* Pugna's Decrepify prevents the target from taking physical damage or doing damage, which poses a huge problem for Lycan, as he mainly deals physical damage.
Sniper
* Invoker's arsenal of magical spells are troublesome for Sniper who has low HP and high armor, which does not benefit him much against Invoker.
* Besides magical damage, he can be disarmed and repeatedly mini-stunned with 
Cold Snap, preventing him from reacting.
* Leveling 
Quas can allow Invoker to lane effectively against Sniper despite right-click harassment.
Pugna
* Because Invoker relies on casting a large amount of spells to contribute to fights, Nether Ward can force him to not cast anything at all or take a large amount of damage to cast spells.
Additional:
* Nether Ward on its own can greatly hinder Invoker from casting many of his abilities, at least until he gets a significant amount of HP or is under the protection of spell immunity from Black King Bar
* Life Drain provides True sight, revealing Invoker through Ghost Walk, and forcing him or his allies to use an ability or item to interrupt its channeling
* Outside of Nether Ward's range, Invoker shall have the advantage, as Invoker has Tornado to purge Pugna's Decrepify when it is used defensively, Tornado or Cold Snap to prevent Pugna from channeling Life Drain
* A poorly used Decrepify on Pugna's allies means Invoker's abilities can be used to deal more damage to them.
Sniper
* Sniper is very fragile, along with his low movement speed, make an exceptionally easy target for Chaos Knight to initiate on.
Phantasm or escape a 
Reality Rift and 
Chaos Bolt combo.
* Sniper has no innate ability to deal with
* In most cases, Sniper likes to stay far in the backline to deal damage, thus he is vulnerable if Chaos Knight manages to jump in the back line, which will usually spell a quick end for Sniper.
Pugna
* Life Drain does not instantly kill the illusions from
Phantasm
Chaos Bolt and 
Reality Rift can easily interrupt the channeling from Life Drain.
Reality Rift makes it harder for Pugna to keep his distance between Chaos Knight.
*
*
* Nether Ward barely deals any significant damage on Chaos Knight as Chaos Knight's abilities do not cost a lot of mana
* The overwhelming damage of Chaos Knight and his illusions will do a quick work on Pugna's poor HP pool, or safely remove the Nether Ward from the battlefield.