Tidehunter
* 
Fury Swipes will keep stacking on Tidehunter since it cannot be dispelled by Kraken Shell and its bonus damage cannot be reduced by Anchor Smash.
* 
Enrage dispels the slow from Gush, and if upgraded with 
Aghanim's Scepter, can even dispel Ravage's stun.
Medusa
* Ursa's status resistance from Enrage reduces duration of Medusa's Stone Gaze.
* Ursa can stack damage with Fury Swipes easily against her Mana Shield in a prolonged team match.
Additional:
* Medusa's tankiness doesn't help her very much against Fury Swipes in long teamfights.
* With no escape mechanism and a slow movement speed, getting jumped on by Ursa usually spells a quick end for Medusa in the early game.
Tidehunter
* Both 
Gush and 
Ravage do little damage against Counterspell.
* Blink helps Anti-Mage escape through 
Anchor Smash.
* Tidehunter's small mana pool can be eated by Mana Break, preventing to spam his abilities and ignores the protection from 
Kraken Shell.
Additional:
* 
Mana Break quickly burns Tidehunter's mana pool, preventing him from spamming his abilities, and Kraken Shell does not mitigate the bonus damage component.
* 
Blink allows Anti-Mage to enter combat quickly and safely after Ravage.
* A well-timed 
Counterspell can reflect Gush back at Tidehunter.
Medusa
* Anti-Mage easily destroys 
Mana Shield with Mana Break, especially once he has 
Manta Style.
* Anti-Mage effectively avoids 
Stone Gaze with Blink, and can reinitiate after its duration is over.
Additional:
* Mana Break burns Medusa's mana easily, especially when coupled with a Manta Style.
* Can easily initiate on Medusa with Blink, burning her mana or forcing her to use Stone Gaze.
* 
Mana Void is effective against Medusa's big mana pool and mana usage, presenting a huge hazard to Medusa's allies around her since her Mana Shield still gives her some protection if she has mana.
Tidehunter
* 
Dark Pact dispels debuffs from Gush, Anchor Smash and even Ravage if timed correctly.
* Kraken Shell cannot restore attributes stolen by 
Essence Shift or dispel the leash if he gets 
Pounced.
Medusa
* Medusa is especially vulnerable to Essence Shift, as both strength and intelligence contribute to her effective HP, while agility contributes to her damage.
* Dark Pact when timed right can be used to dispel Stone Gaze right after it petrifies Slark, allowing him to keep attacking Medusa throughout the duration.
Additional:
* Medusa cannot chase Slark in any way and has no disable beyond her ultimate, making her unable to stop him getting away and regenerating before coming back to finish her off.
* Essence Shift particularly removes 1 intelligence point per hit, thus lowering Medusa's mana pool's cap and leaving her much more vulnerable in prolonged fights.
Tidehunter
* Kraken Shell provides no protection against 
Omnislash or 
Swiftslash.
* If timed correctly, Omnislash, Swiftslash and 
Blade Fury are all capable of dodging Ravage, giving Juggernaut several tools to render your strongest ability moot.
* Blade Fury is an effective way to harass Tidehunter in the laning stage as Tidehunter has no means of getting Juggernaut away from him. 
Healing Ward also greatly minimizes Tidehunter's ability to harass Juggernaut.
* 
Blade Dance minimizes the effectiveness of Anchor Smash's damage reduction.
Medusa
* Heroes that build 
Diffusal Blade or can fit it well into their item build will also make Medusa much less tanky: 
Riki, 
Naga Siren, 
Terrorblade, 
Juggernaut, 
Spectre, 
Slark.
Tidehunter
* Heroes with low mana pools (eg.
Doom and
Tidehunter) will feel the effects of Silencer's Intelligence Steal far more than others.
Medusa
* Silencer burns easily through her effective HP from Mana Shield, by taking away her intelligence.
* 
Arcane Curse punishes her repeatedly casting 
Mystic Snake to keep her mana pool high. He can force her to use Manta Style before he has cast 
Global Silence and 
Medusa usually does not want to build 
Black King Bar.
Tidehunter
* Heroes who relies on high armor such as 
Dragon Knight, Tidehunter, and 
Pudge can be melted by Eye of the Storm.
Additional:
* Kraken Shell's dispel does not restore damage stolen by 
Static Link, and the stolen damage easily offsets Anchor Smash's damage reduction. Razor can keep attacking Tidehunter from afar, denying his chance to use Anchor Smash.
* 
Eye of the Storm melts Tidehunter's armor and makes him much less tanky.
* Razor can chase Tidehunter by himself without relying on actual crowd control ability, so the strong dispel from Kraken Shell is less useful.
Medusa
* With Static Link, Razor can effectively make Medusa useless in teamfights by reducing her main damage output. It can, however, be blocked by a 
Linken's Sphere.
* 
Plasma Field allows Razor to get on top of Medusa, slowing her already slow movement speed to a mere crawl.
* Eye of the Storm capitilizes on Medusa's low armor and causes her to be very vulnerable, even through Mana Shield.
Tidehunter
* Melee heroes who may struggle to get close to Sniper: 
Wraith King, 
Kunkka, Doom, Tidehunter, 
Underlord, 
Troll Warlord, and etc.
Medusa
* Sniper can outrange both Medusa's arrows and Stone Gaze, allowing him to focus her down during a teamfight.
Additional:
* Medusa is a fairly immobile hero that deals damage around her with 
Split Shot. Sniper should outrange her and should stay out of harm's way from Split Shot.
* More importantly, Sniper should have enough attack range to fire at Medusa during her Stone Gaze without turning to stone, so the ultimate is mostly wasted against him.
Tidehunter
* Kraken Shell's dispel does not restore mana lost through 
Astral Imprisonment, and the stolen mana can really hurt Tidehunter's ability to initiate
* 
Arcane Orb high pure damage ignores Tidehunter's Armor, and is barely affected by his Kraken Shell's damage block
* It is also completely unaffected by Anchor Smash, due to it relying on Outworlds Mana pool
* 
Sanity's Eclipse is effective on Tidehunter's poor mana pool, While it is reduced by Kraken Shell, the damage reduction is negligible.
Medusa
* He can use either his own or his double's 
Flux to bypass the spellblock from Linken's Sphere, using the leftover Flux + 
Spark Wraith to slow Medusa's already low move speed to a crawl.
* Arc Warden has a farming advantage with double 
Hand of Midas, and can generally bully Medusa with other items that benefit from duplication.
Tidehunter
* In the mid-game, Tidehunter relies on Kraken Shell to stay alive and get his Ravage off. Apart from Thunder Strike, none of Disruptor's abilities can be dispelled, so it's rather easy to trap him inside Kinetic Field and Static Storm.
* Be mindful, however, that Kraken Shell still makes Tidehunter very tanky, so be sure that you can kill him with your combo or your partners while he is silenced and trapped.
Medusa
* 
Burning Spear's damage over time can rapidly burn Medusa's mana and health alike.
* 
Inner Fire can slow and disarm Medusa and also allow Huskar to follow up with Life Break.
Tidehunter
* 
Viper STrike cancels out Kraken Shell and stops the hard dispel from passively activating, preventing Tidehunter from functioning as a frontline tank.
* Anchor Smash is mostly irrelevant against a ranged hero like Viper.
* Tidehunter relies on the threat of Ravage, which has an obscenely long cooldown. Viper can exploit the downtime with his short cooldowns.
Tidehunter
* Kraken Shell neither dispels nor provides damage reduction against 
Spirit Siphon. This ability also drains health based on percentage damage, making Tidehunter's large healthpool a very appealing target. Furthermore, the health gained from the Siphon is independent from the amount of damage dealt, so Death Prophet will always heal a large amount of from Tidehunter's pool even if Tidehunter has magic reduction items or abilities on him, which makes her an untargetable enemy for you as this easily outweights any damage output you can provide.
* 
Exorcism is yet another ability from which Kraken Shell provides no useful protection, as the spirits completely ignore the damage block and are unaffected by the dispel. This ability also creates an unfriendly area where your blink will be constantly cancelled, reducing your ability to land a good Ravage.
* Ravage does not stop neither Spirit Siphon nor Exorcism, making the ability mostly ineffective against her. Additionally, Death Prophet usually builds 
Eul's Scepter of Divinity, which can be used to dodge the stun entirely.
Medusa
* E.M.P. allows Invoker to burn Medusa's mana to weaken Mana Shield.
* Medusa's lack of mobility makes her easy to kite with Invoker's spells.
Additional:
* 
E.M.P. is a large mana burn nuke which can hit Medusa's Mana shield with enough damage to lose even more mana.
* 
Deafening Blast disarms Medusa's ability to deal pseudo-AOE damage during teamfights.
* 
Cold Snap allows the opposing team to repeatedly stun Medusa in short succession, preventing her from successfully casting her ultimate due to its long cast time.
Medusa
* Heroes who take a long time to become strong are in for a rough mid game, such as 
Outworld Destroyer, 
Magnus, Medusa, and 
Anti-Mage.
Medusa
* Heroes with extremely slow movement speed will cripple against Solar Bind: Medusa, 
Viper
Additional:
* 
Will-O-Wisp will keep Medusa busy after she got hit by 
Blinding Light.
Medusa
* Heroes that build Diffusal Blade or can fit it well into their item build will also make Medusa much less tanky: Riki, Naga Siren, Terrorblade, Juggernaut, Spectre, Slark.
Tidehunter
* Positioning-reliant heroes (
Windranger, Tidehunter, 
Ursa...), since Earth Spirit can disrupt positioning with his Boulder Smash.
Medusa
* Heroes that build Diffusal Blade or can fit it well into their item build will also make Medusa much less tanky: Riki, Naga Siren, Terrorblade, Juggernaut, Spectre, Slark.
Medusa
* Hard carries who just want to farm and be left alone will not appreciate Primal Beast, heroes such as Medusa, 
Drow Ranger...
Tidehunter
* Heroes with strong team-fight abilities (especially ultimates) like Tidehunter, 
Brewmaster, 
Death Prophet, etc.
Additional:
* 
Fade Bolt reduces damage output of Anchor Smash.
* Ravage is an easy target to 
Spell Steal, so always be sure to use Anchor Smash immediately after Ravage when playing against a Rubick.
* Spells stolen by Rubick are potentially stronger due to the lack of cast animations, his talents, and his passive, 
Arcane Supremacy.
Medusa
* Other heroes who has armor and slow debuffs won't allow Medusa to disengage from combat: Tidehunter, 
Bristleback, 
Slardar.
Medusa
* With 
Smoke Screen, Riki will silence and catch Medusa in a surprise with high miss chance flushing her from positions easily in team fights.
* He can deal a huge amount of damage through 
Cloak and Dagger, even through Mana Shield.
Tidehunter
* Riki doesn't deal burst damage.Durable heroes (
Axe, Tidehunter etc.) will usually survive a jump from him,move out of Smoke Screen and potentially retaliate.
Medusa
* 
Bulwark can make each of Medusa's attacks target him instead, reducing Medusa's contribution on team fights.
* 
Spear of Mars stuns Medusa and also pushes her away from teamfights, taking advantage of Medusa's low mobility.
* 
Arena Of Blood blocks Medusa's attacks from outside the arena.
Medusa
* Medusa's Stone Gaze forces Mars to choose between getting petrified, or turning his vulnerable back on Medusa.
Tidehunter
* Tidehunter takes close to no damage from Undying's zombies once he maxes out his Kraken Shell, especially if he gets the level 20 Kraken Shell upgrading talent. This might allow him to blink away to safety.
Medusa
* Split Shot can destroy Tombstone Zombies and Tombstone itself while still damaging heroes.
Tidehunter
* Kraken Shell grants him massive physical attack protection
* Anchor Smash will wipe the area, clearing Lycan's wolves.
Medusa
* Her Mana Shield is too tough for Lycan to break.
* Mystic Snake can hit for a massive damage once it spread between his summons.
Additional:
* Can be easily petrified despite his speed.
* Summoned wolves will be targeted by Split Shot or Mystic Snake
Tidehunter
* Tidehunter's Anchor Smash will cripple all of Enigma's Eidolons, and at a higher level, Tidehunter will be capable to instantly kill the whole group of them for a boost of gold.
* Kraken Shell negates Eidolons's damage and Enigma's auto attacks, making laning against Tidehunter nearly impossible for Enigma.
* Ravage has an insane radius, and considering that Enigma is prone to waiting around for a 
Blink Dagger and Black King Bar combo, Ravage's stun may catch Enigma off guard and put Blink Dagger on cooldown, limiting him a crucial teamfight time.
Medusa
* Medusa's Split Shot can make quick work of Enigma's Eidolons and take advantage of their considerable bounty.
* Medusa can also kill Eidolons with her Mystic Snake that can also greatly damage Enigma and drain some of his mana.
* If Medusa activates Stone Gaze at the start of a fight, it can make initiating and landing an effective 
Black Hole exceedingly difficult, because Stone Gaze can cancel Enigma's Black Hole even through spell immunity, which can discourage Enigma from even trying to initiate with Black Hole.
Additional:
* Medusa's Split Shot can make quick work of Enigma's Eidolons and take advantage of their considerable bounty.
* If Medusa activates Stone Gaze at the start of a fight, it can make initiating — and landing an effective Black Hole exceedingly difficult. Stone Gaze can cancel Enigma's Black Hole even through spell immunity, which can discourage Enigma from initiating with Black Hole.
Tidehunter
* Visage's Familiars cannot penetrate Kraken Shell and will do almost no damage to Tidehunter even with 
Medallion of Courage or 
Solar Crest.
* Anchor Smash's bonus damage has the potential to kill Familiars.
Medusa
* Visage's familiars are easy targets to Split Shot.
* Mana Shield will resist Soul Assumption instances without effort.
Tidehunter
* Durable heroes: Axe, 
Dawnbreaker, Bristleback, 
Mars, 
Omniknight, Tidehunter, Wraith King, 
Primal Beast, Underlord.
Medusa
* If Medusa activates Stone Gaze before Spirit Breaker reaches her with Charge of Darkness, the charge will inevitably fail.
* Medusa has three ways to counter Spirit Breaker's Charge of Darkness: Stone Gaze can disable Spirit Breaker's Charge of Darkness if he faces Medusa directly. Aghanim's Scepter upgraded Mystic Snake can disable Spirit Breaker and cancel his Charge of Darkness if it hits him. And 
Cold Blooded provided by 
Aghanim's Shard that can cast a single-targeted Mystic Snake at Spirit Breaker if he uses Charge of Darkness on her.
* Mana Shield and overall tankiness allows Medusa to easily survive Spirit Breaker's initiation. And to make things worse, Spirit Breaker is not a common Diffusal Blade nor 
Disperser wielder to counter this problem at all.
* Overall, any attempt for Spirit Breaker to gank and kill Medusa will hurt him more than the other way around.
Tidehunter
* Heroes who can stun multiple units at once: 
Dark Willow, 
Spirit Breaker, Slardar, 
Invoker, and Tidehunter.
Medusa
* Poof won't damage Medusa and she can use Stone Gaze to disable all of Meepo's clones.
* Mystic Snake will easily become the bane of Meepo early game.
Tidehunter
* Any hero who can counter-initiate in anticipation without getting caught in Reverse Polarity: 
Sven, Omniknight, 
Enigma, 
Luna, Naga Siren, Mars, 
Jakiro, 
Venomancer, 
Elder Titan, 
Faceless Void, 
Rubick, 
Keeper of the Light, 
Pugna, Invoker, Spectre, 
Alchemist, 
Treant Protector, 
Lina, 
Oracle, 
Zeus, 
Shadow Shaman, 
Phoenix, 
Razor, 
Huskar, 
Batrider, Kunkka, Tidehunter, Wraith King, 
Sand King, Medusa, Dawnbreaker.
Medusa
* Any hero who can counter-initiate in anticipation without getting caught in Reverse Polarity: Sven, Omniknight, Enigma, Luna, Naga Siren, Mars, Jakiro, Venomancer, Elder Titan, Faceless Void, Rubick, Keeper of the Light, Pugna, Invoker, Spectre, Alchemist, Treant Protector, Lina, Oracle, Zeus, Shadow Shaman, Phoenix, Razor, Huskar, Batrider, Kunkka, Tidehunter, Wraith King, Sand King, Medusa, Dawnbreaker.
Tidehunter
* Heroes such as 
Lone Druid, Tidehunter and Viper can be very problematic for Phantom Assassin because they give her very little time to farm and become scary.
Medusa
* Heroes with disables that ignore spell immunity will render Phantom Assassin completely useless in teamfights throughout the game: Axe, Enigma, 
Vengeful Spirit, Doom, 
Bane, 
Beastmaster, Pudge, Medusa, 
Warlock.
Tidehunter
* Kraken Shell easily dispels the lengthy stun from 
Shackleshot.
* Kraken Shell (and possibly Anchor Smash) blocks huge amount of damage from 
Focus Fire.
* Anchor Smash is one of the few sources of True Strike, which means Tidehunter can deal significant damage through 
Windrun, while also reducing Windranger's damage output.
Additional:
* Kraken Shell can easily dispel Shackleshot after he has taken a certain threshold of damage.
* Ravage provides excellent lockdown against Windranger, allowing his teammates to kite her throughout the game.
* When Tidehunter has Aghanim's Shard, he will gain access to 
Dead in the Water, allowing him to lock down Windranger at any time. When Windranger tries to move away from the anchor with Windrun, she will be effectively slowed, preventing her from escaping.
Tidehunter
* Kraken Shell can dispel Flaming Lasso.
* If Batrider drags Tidehunter back towards his team, it can be setup for a well placed Ravage.
Additional:
* Kraken Shell is very useful against 
Sticky Napalm and 
Flamebreak, easily dispelling them regularly.
* Tidehunter is probably the worst hero to target with 
Flaming Lasso, as Kraken Shell will remove it and Tidehunter often survives long enough to cast Ravage in the middle of Batrider's team. At the same time, if Batrider initiates on his teammate, Tidehunter will have the perfect opportunity to counter-initiate.
Medusa
* Medusa's Split Shot can easily kill Chen's creeps.
* Mystic Snake can quickly kill Chen's creeps and deal intense damage for every killed creep while also draining their mana with each bounce. Aghanim's Scepter upgraded Mystic Snake can also disable both, Chen and his creeps upon impact.
* Mana Shield will make it impossible for Chen to burst down Medusa.
* Stone Gaze can disable Chen from using 
Hand of God to save himself or his allies.
Medusa
* Enchantress often has a small army of neutral creeps, allowing Medusa to hit her with a later bounce of her Mystic Snake.
Medusa
* Stone Gaze allows Medusa to easily kite and kill Sven.
* Mana Shield negates much of Sven's burst damage.
Additional:
* Mana Shield makes it very hard for Sven to burst her within Storm Hammer's stun duration.
* Stone Gaze makes it very difficult for Sven to fight Medusa at any stage of the game.
* Mystic Snake can slow Sven down enough for allies to capitalize on his commitment in a fight.
Tidehunter
* Ravage damages and disables Chaos Knight and his illusions.
* Anchor Smash deals respectable area damage, especially to Phantasms and lowers Chaos Knight's damage output.
* Kraken Shell dispels Chaos Bolt and Reality Rift while providing protection from damage.
Medusa
* Split Shot will keep attacking Pangolier even when he is rolling around.
* Stone Gaze stuns Pangolier during Rolling Thunder, or forces him to roll away.
Tidehunter
* Kraken Shell dispels both Shadowraze's damage amplification stacks and Requiem of Soul's damage reduction (provided Tidehunter has taken enough damage).
* Ravage cancels Requiem of Souls if Shadow Fiend isn't protected by Black King Bar.
Additional:
* Kraken Shell dispels the damage amplification stacks of 
Shadowraze as well as the damage reduction from 
Requiem of Souls (provided he has taken enough damage).
* Anchor Smash reduces Shadow Fiend's large attack damage, Kraken Shell makes Tidehunter the last target Shadow Fiend wants to attack.
* Ravage can easily cancel Requiem of Souls if Shadow Fiend isn't protected by Black King Bar.
Tidehunter
* Kraken Shell dispels 
Dual Breath, 
Ice Path, 
Liquid Frost, 
Liquid Fire and even 
Macropyre's Burn.
* It also completely negates the damage from Liquid Fire and Ice path, while heavily reducing the damage from all of his other abilities
* Jakiro is a naturally slow hero, Gush will allow you to easily catch him, while also reducing his Armor
Tidehunter
* Kraken Shell dispels the stun from Paralyzing Cask. However, it does not dispel the damage from Maledict.
* Once Witch Doctor first uses his Death Ward in team fights, Tidehunter can simply cancel it with Ravage, turning the tables against him, especially if Witch Doctor does not have a Black King Bar.
* As a precaution, Witch Doctor should let Tidehunter use Ravage first before channeling Death Ward to turn a team fight in his favor.
Tidehunter
* Kraken Shell can dispel Dismember after reaching a certain threshold of damage.
* Tidehunter's naturally high health, strength gain, and common itemization for survivability through magic resistance makes Tidehunter a poor target.
Tidehunter
* Gush can make Crystal Maiden's already weak armor even weaker.
* Kraken Shell can dispel Frostbite, preventing him from getting stuck inside Freezing Field.
* Ravage is very useful for interrupting Freezing Field, even while Crystal Maiden is under the effects of 
Glimmer Cape. Crystal Maiden must purchase a Black King Bar, which is far more costly.
Tidehunter
* Ravage, being an AoE disable, cancels Epicenter's channeling from a long range, limiting his potential to counter-initiate.
* This can be remedied, however, by first using a Black King Bar, then channel Epicenter, then finally initiate with Blink Dagger.
Tidehunter
* Vengeful Spirit should carefully consider whether to use her Nether Swap on Tidehunter, as it can easily position him for a Ravage on Vengeful Spirit and her allies.
* Due to Magic Missile's high damage, Kraken Shell will often proc and clear Tidehunter's debuffs.
Medusa
* Mana Shield makes it very difficult for Bloodseeker to gain his Thirst bonuses.
* Rupture rarely kills Medusa through Mana Shield.
Medusa
* Mana Shield makes Medusa very hard to take down in Duels.
* Stone Gaze stops Legion Commander from Dueling altogether, regardless of who she targets.
Medusa
* Lifestealer's low mobility makes him easy to kite.
* Stone Gaze pierces 
Rage, wasting its cooldown and making Lifestealer unable to fight.
Tidehunter
* Most summons and illusions can barely hurt Tidehunter at all, after their attacks get reduced by Anchor Smash and blocked by Kraken Shell: 
Nature's Prophet, Enigma
* Also Ravage's large area of effect and damage can easily damage all those units at once, or just straight up clear them.
Medusa
* Heroes with Linken's Sphere as core item: 
Weaver, 
Morphling, Medusa.
Medusa
* Other heroes who has armor and slow debuffs won't allow Medusa to disengage from combat: Tidehunter, Bristleback, Slardar.
Tidehunter
* Tidehunter's Kraken Shell dispels Corrosive Haze and Bash of the Deep's stun if enough damage is taken. Anchor Smash and Kraken Shell's damage block also reduces Slardar's damage.
Medusa
* Medusa cares less than other heroes about armor reduction, since Mana Shield blocks 70% of all damage without taking armor/magic resistance into consideration. This makes 60% of your Corrosive Haze ineffective until Medusa's mana is drained.
Tidehunter
* Luna often builds Black King Bar, and none of Tidehunter's spells can bypass spell immunity.
* Though Anchor Smash can weaken Luna's physical damage, it does not weaken her magical damage, which means that 
Lucent Beam and 
Eclipse deal a lot of magic damage in the early and mid-game, which can bypass Tidehunter's Kraken Shell.
Additional:
* Luna often builds Black King Bar, and none of Tidehunter's spells can bypass spell immunity.
* Though Anchor Smash can weaken Luna's physical damage, it does not weaken her magical damage, which means that Lucent Beam and Eclipse deal a lot of magic damage in the early and mid-game, which can bypass Tidehunter's Kraken Shell.
Tidehunter
* Heroes that rely on base damage: Luna, 
Phantom Lancer are easily countered with Anchor Smash.
Medusa
* Should Luna choose to buy Manta Style, Medusa will be able to kill illusions from them with Split Shot and 
Mjollnir, which is a common item on Medusa.
* Mystic Snake allows Medusa to easily harass Luna and steal mana from her, preventing Luna from retaliating with Lucent Beam.
* Medusa can survive Eclipse thanks to Mana Shield, which can cause Luna to struggle greatly in bursting down Medusa and force her to buy Diffusal Blade and it's upgrade Disperser.
* Even with Black King Bar, Medusa's Stone Gaze will still be able to disable Luna, which could even discourage her from counter-initiating with Eclipse.
Additional:
* Should Luna choose to buy Manta Style, Medusa will be able to kill illusions from them with Split Shot and Mjollnir, which is a common item on Medusa.
* Mystic Snake allows Medusa to easily harass Luna and steal mana from her, preventing Luna from retaliating with Lucent Beam.
* Medusa can survive Eclipse thanks to Mana Shield, and since Luna is not a hero that often goes for Diffusal Blade, she will struggle greatly in bursting down Medusa.
* Even with Black King Bar, Medusa's Stone Gaze will still be able to disable Luna, which could even discourage her from counter-initiating with Eclipse.
* For the same reasons, Medusa makes a very powerful ally for Luna when they are in the same team.
Tidehunter
* Heroes that excel at grouping up with their team very early will be able to take advantage of a Clinkz that tries to pick off heroes that are alone: Brewmaster, 
Dazzle, Tidehunter.
Medusa
* Heroes with strong area-of-effect damaging and/or disabling abilities will be able to intercept Underlord and his team when they exit from Fiend's Gate: Luna's Aghanim's Scepter upgraded Eclipse, Dawnbreaker's 
Solar Guardian, Axe's 
Berserker's Call, Mars's Arena of Blood, Jakiro's Macropyre, Dual Breath and Ice Path, Naga Siren's 
Song of the Siren, Razor's Eye of the Storm and Plasma Field, Lina's 
Light Strike Array, 
Broodmother's 
Spinner's Snare from Aghanim's Scepter, Elder Titan's 
Earth Splitter and 
Echo Stomp, Alchemist's 
Unstable Concoction and 
Acid Spray, 
Queen of Pain's 
Sonic Wave, 
Dark Seer's 
Wall of Replica and 
Vacuum, Venomancer's 
Noxious Plague and 
Poison Nova from Aghanim's Scepter, Oracle's 
Fortune's End and 
Rain of Destiny from Aghanim's Shard, 
Bloodseeker's 
Blood Rite, Enigma's Black Hole and 
Midnight Pulse, 
Shadow Fiend's Requiem of Souls, Batrider's Aghanim's Scepter upgraded Flaming Lasso, 
Firefly, Flamebreak and Sticky Napalm, 
Ancient Apparition's 
Ice Blast, Sand King's 
Epicenter, 
Sand Storm and 
Burrowstrike, 
Gyrocopter's 
Call Down, 
Ember Spirit's 
Sleight of Fist, Death Prophet's Exorcism and 
Silence, 
Monkey King's 
Wukong's Command, 
Crystal Maiden's 
Freezing Field, 
Muerta's 
The Calling, Medusa's Stone Gaze, Zeus's 
Nimbus from Aghanim's Scepter. Dark Willow's 
Bramble Maze, 
Pangolier's 
Swashbuckle, 
Grimstroke's 
Soulbind, 
Ink Swell and 
Stroke of Fate, 
Earthshaker's 
Echo Slam and 
Fissure, 
Puck's 
Dream Coil and 
Waning Rift, 
Winter Wyvern's 
Winter's Curse, Magnus's 
Reverse Polarity.
Medusa
* Heroes with a lot of burst damage, especially those who rely on casting spells: Lina, Zeus.
Medusa
* Heroes with a lot of burst damage, especially those who rely on casting spells: Lina, Zeus.
Medusa
* Heroes that are hard to gank: Axe, Death Prophet, Phantom Lancer, Slark, 
Centaur Warrunner, Bristleback, Medusa, Mars.
Tidehunter
* Tidehunter with Kraken Shell when damage received reaches the threshold.
* Heroes that can remove the Track debuff with their skills:
* 
Abaddon with 
Aphotic Shield and 
Borrowed Time
* Huskar with 
Life Break
* Juggernaut with Blade Fury
* 
Legion Commander with 
Press the Attack
* 
Lifestealer with Rage and 
Infest
* Naga Siren with 
Mirror Image
* Omniknight with 
Heavenly Grace
* Oracle with Fortune's End and 
False Promise
* Phantom Lancer with 
Doppelganger
* Slark with Dark Pact
* Ursa with Enrage
* Weaver with 
Time Lapse
* Tidehunter with Kraken Shell when damage received reaches the threshold.
Medusa
* Heroes that build Diffusal Blade or can fit it well into their item build will also make Medusa much less tanky: Riki, Naga Siren, Terrorblade, Juggernaut, Spectre, Slark.
Medusa
* Medusa's Split Shot and Mystic Snake combined with Mjollnir, a common item for Medusa, will whittle down all of Naga Siren's illusions, including Naga Siren herself.
* Medusa's Stone Gaze can disable Naga Siren even for the duration of Song of the Siren and even if Naga Siren is spell immune, discouraging Naga Siren from even trying to use Song of the Siren to save herself or counter-initiate against Medusa.
Additional:
* Medusa's Split Shot and Mystic Snake combined with Mjollnir, a common item for Medusa, will whittle down all of Naga Siren's illusions, including Naga Siren herself.
* Medusa's Stone Gaze can disable Naga Siren even for the duration of Song of the Siren and even if Naga Siren is spell immune, discouraging Naga Siren from even trying to use Song of the Siren to save herself or counter-initiate against Medusa.
Tidehunter
* Infernal Blade deals scaling damage and is useful against high HP targets such as Tidehunter.
* 
Doom prevents Tidehunter from casting his Gush, Anchor Smash and Ravage, making him useless in team fights.
* If Doom chooses the Level 25 talent {ValueColor:1|Doom applies Break|25tal} {Symbol:Talent}, he can also disable Kraken Shell, reducing his survivability.
Medusa
* Doom does not disable Mana Shield. As such, Doom's damage is largely mitigated by her mana shield. Additionally, Medusa is not reliant on her abilities to be effective during a teamfight, making Medusa an unproductive hero to target.
* Medusa is an ideal Linken's Sphere carrier. Should one be purchased, and without any additional disables, Doom may find that few opportunities exist to effectively lockdown, disable, and kill Medusa.
Medusa
* Phantom Lancer with Diffusal Blade will very quickly burn Medusa's mana, making Mana Shield significantly less effective.
* Doppelganger's 1 second invulnerability can be used to dodge Medusa's petrification from Stone Gaze, as well as Mystic Snake.
* Phantom Lancer's illusions outnumber Medusa's targets from Split Shot, likely shielding his team in the process.
Tidehunter
* Kraken Shell and Anchor Smash makes it very difficult for Phantom Lancer's illusions to deal damage to Tidehunter.
* Ravage will stun the real Phantom Lancer while clearing most of his illusions.
* Anchor Smash reduces base damage, which is the majority of Phantom Lancer's auto-attack damage.
* An Aghanim's Scepter upgraded Gush slows down and reduces all of Phantom Lancer's illusions.
Additional:
* A dozen of Phantom Lancer's illusions with all their might can barely hurt Tidehunter at all thanks to Kraken Shell and Anchor Smash. The only way Phantom Lancer can hurt Tidehunter is through the mana burn provided by Diffusal Blade.
* Even with high chasing power from 
Spirit Lance and 
Phantom Rush (and even Diffusal Blade), Tide Hunter can shrug it all off with Kraken Shell and escape by using a 
Town Portal Scroll or just moving away.
* The AoE nukes from Ravage, Anchor Smash, and an Aghanim's Scepter-upgraded Gush can clear Phantom Lancer's illusions easily.
Tidehunter
* Heroes with large physical resistance do not counter Muerta's 
Pierce the Veil such as Omniknight or Tidehunter.
Medusa
* Any long duration disables that can pierce through both, Pierce The Veil and Black King Bar are devastating against Muerta: Enigma's Black Hole, Dawnbreaker's Solar Guardian, Axe's Berserker's Call, Naga Siren's Aghanim's Scepter upgraded 
Ensnare and 
Reel In from Aghanim's Scepter, Jakiro's Aghanim's Scepter upgraded Macropyre, Bane's 
Fiend's Grip, Pudge's 
Dismember, Batrider's Flaming Lasso, Beastmaster's 
Primal Roar, Grimstroke's Soulbind, Medusa's Stone Gaze, Magnus's Reverse Polarity.
Medusa
* Medusa lacks mobility or escape mechanisms. 
Earth Spike and 
Hex can neutralize her strong damage potential and allow for 
Lion's team to focus her down.
* 
Mana Drain is a perfect ability to weaken Medusa's durability as it can quickly drain her Mana Shield, making her far less tanky. Mana Drain can also be used to restore mana of Lion's allies, which can nullify the mana steal from Mystic Snake.
* Mana Drain, along with Hex, destroy illusions instantly, which may be extremely helpfull and efficient against core builders of Manta Style, like Medusa herself.
Tidehunter
* Tidehunter is a core builder of 
Pipe of Insight. Along with natural high health pool, it's tough to burst the Leviathan down.
* Kraken Shell thwarts long disables attempts if Tidehunter receives enough damage.
* Gush and Ravage long cast and reach ranges will effortlessly hit Lion, either bursting him down or making him extremely vulnerable and worn in matter of seconds.
Tidehunter
* No matter how Tidehunter builds tanky items such as (
Guardian Greaves, 
Crimson Guard or Pipe of Insight), all it needs is for him to fall below a certain percentage of health for him to fall to Reaper's Scythe.
Medusa
* Mana Shield can tank most of the damage from Reaper's Scythe; with sufficient mana, the kill threshold drops significantly.
* Necrophos has a movement speed equal to Medusa, and is easy to chase down with a slowing item in Medusa's inventory.
Medusa
* Fiend's Grip provides mana drain, which can heavily damage Mana Shield and prevent Medusa from using Stone Gaze.
* Even if she does use Stone Gaze, Nightmare can buy enough time to protect allies and reset the fight.
Additional:
* Fiend's Grip leaves Medusa defenseless, since not only does it deal damage, it also drains mana.
Tidehunter
* Kraken Shell dispels Fiend's Grip, wasting it easily. Additionally, in late game, it secures premature dispell of a level 4 Nightmare, in case of continuous Bane's rightclicks.
* Enfeeble only reduces distance of Gush, but not of Anchor Smash or Ravage, and thanks again to Kraken Shell, is easily dispellable for him in team fights.
* Ravage affects large area, effectively reaching Bane's spot for applying Fiend's Grip, even with Glimmer Cape, Aether Lens and/or Aghanim's Scepter.
Additional:
* Kraken Shell dispels Fiend's Grip, wasting it easily.
Medusa
* Axe can take advantage of Medusa's awfully low HP to insta-kill her with 
Culling Blade, making it extremely difficult for her to farm for items to compensate for the lack of strength during early and mid-game while Axe is continuously harassing around.
Medusa
* Mana Shield reduces the effectiveness of Counter Helix.
* Stone Gaze makes it very difficult for Axe to initiate on Medusa and her allies.
Medusa
* Webbed areas can be used to hit and run, covering distance hastily weakening her on the way and initiating ganks.
* Even though Medusa can hunt down Spiderlings easily when given enough range, 
Silken Bola will cause her attacks to miss and get her swarmed in no time.
* Medusa usually does not build a Black King Bar to benefit from Mana Shield fully while Broodmother can fit a Diffusal Blade to burn away all of Medusa's mana.
Additional:
* 
Spin Web will allow Broodmother to pick her own fights and sometimes slip away to ambush Medusa.
* Though Medusa's Split Shot and Mystic Snake can help Medusa deal with Broodmother's spiderlings, Broodmother will create too much of them for her to handle, allowing her to outnumber Medusa's targets from Split Shot and shield her team in process.
Tidehunter
* Kraken Shell makes Tidehunter take nearly no damage from Spiderlings.
* Anchor Smash kills Spiderlings in one or two casts, should Broodmother try to swarm Tidehunter with them.
Tidehunter
* Ravage's travel time allows Nyx Assassin to easily stun Tidehunter with
Spiked Carapace.
Vendetta can instantly deplete Tidehunter's low mana pool, especially in the early game, potentially preventing Tidehunter from casting Ravage.
*
Medusa
*
Vendetta burns a significant amount of mana on hit, and the damage from the ability drains Medusa's mana pool even further.
Spiked Carapace if he's within range of Medusa's abilities and isn't invisible.
Aghanim's Scepter extremely hard to deal with if Medusa is the team's main damage source.
Split Shot, Medusa can be easily interrupted by Spiked Carapace during combat, especially during her precious 
Stone Gaze.
Mana Shield, especially if Medusa only increases her mana pool by bolstering intelligence (which has the added bonus of increasing Mana Burn's damage).
Mystic Snake and 
Split Shot can trigger Spiked Carapace.
Medusa lacks single target damage, making a Burrowed Nyx Assassin hard to kill.
* Due to the passive nature of Mystic Snake and Split Shot, it can possibly proc Nyx's
* Medusa lacks single target damage, making Nyx with
Additional:
* With her passive
* Mana Burn quickly destroys
* Uncontrollable damage from
*