* Lifestealer is not affected by Earthbind or Poof during Rage, making him a difficult target to work around.

* Heroes who can do scaling health damage to Primal Beast are very threatening for the hero. Such as: Phoenix, Tinker etc.

* With Aghanim's Scepter, Tinker's Laser completely stops Chaos Knight's damage, forcing him to buy either a Black King Bar for his own survivability while leaving his illusions still vulnerable, or a Monkey King Bar leaving him still vulnerable to Tinker's nukes, though improving his damage.
* Tinker rarely finds himself in the middle of a fight, which is where Chaos Knight typically thrives, and even in the rare cases of being so, at level 3 Tinker's constant rearm and blink away can kite and dodge Chaos Knight's spells reliably, so Chaos Knight has very little catch against Tinker's mobility. This gives Tinker impunity to create more chaos in a teamfight than Chaos Knight can control, laying down the field with March of the Machines and constantly being hit by rockets and lasers.

* Heroes with spell immunity or pseudo-blinks which provide invulnerability: Lifestealer, Juggernaut, Omniknight, Huskar, and Tusk have spells which allow them to easily escape Dream Coil.

* Laser prevents Juxtapose from triggering, as it only triggers on successful attacks
* Laser does high splash, and upgrading it with Aghanim's Scepter makes it deal twice as much damage due to the bounce. Combined with Rearm, Tinker can rapidly deplete Phantom Lancer's illusion army
* However, if Phantom Lancer ambushes Tinker, Tinker will not survive versus Phantom Lancer.

* Heroes with abilities that blind or cause Legion Commander to miss will prevent her from winning Duels: Arc Warden, Keeper of the Light, Riki, Tinker

* Enigma lacks burst damage, and that makes him vulnerable to heroes who can recover themselves and turn the fight around to their advantage after Enigma finishes his initiation: Faceless Void, Terrorblade, Ursa, Weaver, Broodmother, Slark, Abaddon, Wraith King, Lifestealer.

* Heroes with high armor like Dragon Knight, or with abilities to cause attacks to miss like Phantom Assassin, Riki and Tinker will be hard to deal with, as Clinkz relies almost entirely on physical attacks.

* Since Windranger is bad against magical damage, heroes with continuous magical damage or magical nukes can blast her: Zeus, Tinker, Leshrac, Viper, Skywrath Mage, Lion, Lina, Venomancer.

* With Aghanim's Scepter upgraded Infest, Lifestealer can use it on enemy heroes to attack them and disarm them from inside, even if they are spell immune, which can give him the edge over the heroes he's weak against like Ursa, Phantom Assassin, Terrorblade or Troll Warlord.

* Heroes who rely on abilities to deal damage (e.g. Timbersaw, Tinker) can fight a Razor even after Static Link.

* Any hero with a low HP pool is easy for Tinker to nuke down: Crystal Maiden, Enchantress, Gyrocopter, Lion, Riki, Techies, Terrorblade, Necrophos, Invoker.

* Heroes who have most or all their abilities (damage or disable) unable to pierce spell immunity: Keeper of the Light, Lina, Lion, Zeus.

Additional:
* Rage is very useful against Zeus, as it negates magic damage and provides spell immunity. In addition, the increased attack speed can tear Zeus apart in combination with Open Wounds.
* Lifestealer can avoid Thundergod's Wrath with Infest.

* Tinker is one of the few heroes who is able to defeat a Sniper on the center line thanks to his long-ranged abilities.
* Laser allow Tinker to deal damage to Sniper and blind him, causing him to miss attacks more often.
* Heat-Seeking Missile can deal heavy damage to Sniper on lane.
* Defense Matrix allow Tinker to save himself or allies from Assassinate.
* Warp Flare from Aghanim's Shard allows Tinker to teleport Sniper away from himself, while also reducing both his attack range and cast range. If Sniper is teleported near Tinker's allies with Warp Flare, he will be bursted down in no time.
Additional:
* Tinker is one of the few characters in Dota 2 who is able to defeat a Sniper on the center line – Tinker. On the center line, he gains an advantage over his opponent, and later acquires additional control. It is these abilities that the enemy should have in the game against the Sniper.

* Lifestealer can close the distance to Sniper by using Infest on a fast or durable creep to tank Sniper's damage.
* Open Wounds and Ghoul Frenzy will reduce Sniper's mobility heavily, and Rage's movement speed bonus helps in closing the gap to Sniper. It also protects him from Assassinate and Shrapnel.
* Infest can dodge an incoming Assassinate or to surprise Sniper during ganks. Aghanim's Scepter upgraded Infest can also allow Lifestealer to disarm Sniper and attack him from inside.

* Viper is kind of a mixed package. Tinker is very good against him. but stands a better chance against him than most heroes.
* Viper has a high innate magic resistance, but relies on his primary attacks to really deal damage. making Laser an effective way to save allies from him, and deal damage. Keep in mind that his Corrosive Skin will prevent Tinker from blinking.
* Viper's Viper Strike and Poison Attack will also have a hard time damaging allies through Tinker's constant casting of Defense Matrix.
* Viper has no solutions to cancel Rearm nor any of Tinker's escape attempts with Boots of Travel
* However, if Viper gets a jump on Tinker first. Tinker will unlikely survive versus Viper.

* Rage ignores all of Viper's magical damage, although Viper Strike can pierce spell immunity and slows him down.
* Feast and Open Wounds from Aghanim's Shard can be combined to heal through Viper's physical damage.
* Aghanim's Scepter upgraded Infest can be used to disarm Viper, preventing him from using Poison Attack on Lifestealer's allies.

* Heroes with either magical, physical or pure damage burst: Bane, Ember Spirit, Leshrac, Lina, Luna, Nyx Assassin, Phantom Assassin, Skywrath Mage, Tinker, Ursa, Void Spirit.

* Rage gives Lifestealer spell immunity, Chen and his converted creeps have little to no ways of fighting back against Lifestealer whenever he activates it.
* Feast allows Lifestealer to recover himself by damaging Chen's creeps.
* Chen has no escape mechanisms, so he will often be unable to escape from slows applied with Ghoul Frenzy.
* Open Wounds from Aghanim's Shard can severely slow down Chen, and allow Lifestealer and his team to heal themselves by attacking Chen. Open Wounds can also fester and spread if Chen takes enough damage that will trigger the spread while he is affected with Open Wounds.
* Infest allows Lifestealer to infest into one of Chen's converted creeps and take control of it, which allows Lifestealer to either escape from Chen or surprise him. Aghanim's Scepter upgraded Infest can disarm Chen and allow Lifestealer to attack Chen from within, even if Chen is spell immune.

* Any hero with a low HP pool is easy for Tinker to nuke down: Crystal Maiden, Enchantress, Gyrocopter, Lion, Riki, Techies, Terrorblade, Necrophos, Invoker.

* Rage protects Lifestealer from all of Techies's abilities. Reactive Tazer's disarm will also not work on Lifestealer under Rage.
* Rage can also be used to trigger Techies's Proximity Mines safely.
Additional:
* Lifestealer's Rage lets him clear Proximity Mines without taking damage, and allows him to hit heroes whom Techies has used Reactive Tazer on.

* Heroes with high magical or pure damage will bypass Bulwark: Timbersaw, Dark Willow, Enigma, Invoker, Pugna, Skywrath Mage, Tinker, Zeus, Oracle.

* Rage, acting as a pseudo-Black King Bar, completely negates Mars' initiation if used in time.
* Feast does damage and heals based on max health, perfect against high-health strength heroes like Mars.
* Infest allows Lifestealer to potentially save allies from Mars' initiation with a quick burst of extra health.

* Any hero with a low HP pool is easy for Tinker to nuke down: Crystal Maiden, Enchantress, Gyrocopter, Lion, Riki, Techies, Terrorblade, Necrophos, Invoker.

* Rage ignores all of Gyrocopter's magical attacks.
* Feast helps Lifestealer out-damage Gyrocopter at close range.

* Heroes with Evasion or abilities that cause Tiny to miss like Phantom Assassin and Tinker are very effective because of Tiny's low attack speed. Additionally, Monkey King Bar is not a good item for Tiny because of its reliance on high attack speed to proc for magical damage.

* Feast will deal a enormous amount of damage because of Tiny's huge health pool.
* Rage protects Lifestealer from Tiny's magical burst damage.

* Heroes who rely on basic attacks will suffer from Laser: Phantom Assassin, Wraith King, Huskar.

* Rage renders Lifestealer immune to the damage from Burning Spears.
* Feast makes Lifestealer one of few heroes that can outlast Huskar in a one-on-one fight.

* Lion has an incredibly fragile health pool, making him weak against nukers like Tinker or Oracle.

* Heroes who have most or all their abilities (damage or disable) unable to pierce spell immunity: Keeper of the Light, Lina, Lion, Zeus.

Additional:
* Rage makes Lifestealer debuff immune and gives him magic resistance which can drastically reduce magical damage from Lion's abilities while also preventing Lion to do anything to him.
* Lion's lack of inner escape and defensive mechanisms increases Ghoul Frenzy effectiveness, since it applies slows upon attacking.
* Lifestealer's physical damage output is strong against Lion's low health and base armor
* Infest can be used to surprise unsuspecting Lion if he tries to take down alone enemy hero. Aghanim's Scepter upgraded Infest can be used to disarm Lion and attack him from inside, even if Lion is debuff immune with the Aghanim's Shard upgraded Mana Drain.

* Any hero with a low HP pool is easy for Tinker to nuke down: Crystal Maiden, Enchantress, Gyrocopter, Lion, Riki, Techies, Terrorblade, Necrophos, Invoker.

* Juggernaut and Lifestealer have abilities (Blade Fury and Rage respectively) that prevent Crystal Maiden from using her spells on them in the early game, before Black King Bar and other magical reduction is even an issue.

Additional:
* Crystal Maiden is an ideal target for Lifestealer due to her poor mobility and low health pool. Lifestealer can usually catch up to her simply by casting Rage, as none of her abilities pierce through magic immunity. Freezing Field can potentially make her even more vulnerable to Lifestealer while under Rage as she is even more immobile while channeling it.
* Lifestealer commonly buys Abyssal Blade, which allows him to cancel Freezing Field, even if Crystal Maiden is spell immune.
* Alternatively, Aghanim's Scepter upgraded Infest combined with Abyssal Blade and with items that provide attack speed which Lifestealer commonly buys allow him to to cancel Freezing Field from within the Crystal Maiden.

* Heroes with either magical, physical or pure damage burst: Bane, Ember Spirit, Leshrac, Lina, Luna, Nyx Assassin, Phantom Assassin, Skywrath Mage, Tinker, Ursa, Void Spirit.

* Heroes that can easily bypass Io's allies to get to Io: Riki, Tusk, Clinkz, Sniper, Slark, Phantom Assassin, Void Spirit, Storm Spirit, Ember Spirit, Earth Spirit, Spirit Breaker, Lifestealer.

* Tinker's Laser is useful against Outworld Destroyer, as the blind prevents him from landing Arcane Orbs.

* Heroes with built-in spell immunity can become immune to all of Outworld Destroyer's spells: Lifestealer's Rage and Juggernaut's Blade Fury.

* Heroes with magical or pure damage output will not have any problems against Atrophy Aura at all: Luna, Lina, Jakiro, Pugna, Bane, Snapfire, Muerta, Nyx Assassin, Enigma, Tinker, Witch Doctor, Zeus, Crystal Maiden.

* Heroes with spell immunity abilities won't be caught inside by Pit of Malice: Juggernaut, Lifestealer.

* Heroes that commonly attack ethereal units will not have any problems against Muerta's Pierce The Veil: Tinker, Jakiro, Lina, Luna, Pugna or Ogre Magi, Enigma, Batrider, Techies, Broodmother, Dawnbreaker, Shadow Shaman, Bane, Tinker, Venomancer, Arc Warden.

* Lifestealer can activate Rage to become spell immune, making Pierce the Veil do no damage and preventing Dead Shot from fearing or doing damage.
* Lifestealer can use Infest to avoid Muerta's Gunslinger shots, Dead Shot's fear and surprise Muerta. Aghanim's Scepter upgraded Infest can be used to disarm Muerta while she has Pierce the Veil and even through Black King Bar.
* However, Lifestealer has no way of hurting Muerta through Pierce the Veil outside of Infest, Lifestealer's only source of dealing magical damage. This forces Lifestealer to buy Revenant's Brooch.

* Rage allows him to be immune to all of Ezalor's abilities. Also, the increased movement speed combined with the slow from Ghoul Frenzy and the squishy nature of Ezalor allows Lifestealer to take him down very quickly.

* Laser along with Heat-Seeking Missile allows Tinker to quickly burst down Drow Ranger due to her low health.
* Heat-Seeking Missile lets Tinker out-range Drow Ranger and hit her in the backline of a teamfight.

* Being a strength hero with a high strength gain means Feast can give her a hard time,especially later in the game.
* However,Starbreaker's physical damage can control him in the laning phase.

* Rage protects and dispels all of Dark Willow's abilities.
Additional:
* Rage protects Lifestealer from all of Dark Willow's abilities.

* Rage can be used to escape from a Glimpse and to move out of Kinetic Field.
* Infest allows Lifestealer to dodge Glimpse.

* Leshrac's high magic damage is ignored by Rage.
* Lifestealer can get in Leshrac's face with Rage and mitigate any other damage taken by Leshrac with Open Wounds.

* Tinker can use Laser to save an ally or himself from Phantom Assassin's initiate Phantom Strike due to the blind, forcing her to use a Black King Bar to effectively initiate, Tinker can also use Warp Flare one he buys Aghanim's Shard to reverse Phantom Strike's blinking with Phantom Strike.
* Tinker almost never uses his physical attack, relying on his spell-spamming to deal damage which ignores Blur's Evasion
* Defense Matrix prevents Coup de Grace from triggering.

* With Aghanim's Scepter upgraded Infest, Lifestealer can use it on enemy heroes to attack them and disarm them from inside, even if they are spell immune, which can give him the edge over the heroes he's weak against like Ursa, Phantom Assassin, Terrorblade or Troll Warlord.

* Feast is good against high health strength heroes such as Alchemist.
* Rage allows Lifestealer to not be targetable by Unstable Concoction, possibly making Alchemist stun himself.

* Lifestealer's Rage makes him immune to all of Ogre's magical debuffs and also dispels them.
* Ogre's high health pool makes him an ideal target for Feast.
Additional:
* Ogre Magi has nothing against Rage and his high health pool amplifies Feast.

* Rage prevents Earthshaker from damaging and stunning Lifestealer.
* Feast is very effective against Earthshaker, because of him being a strength hero, allowing Lifestealer to heavily harass and kill him.
* Open Wounds prevents Earthshaker from escaping after he initiated.
* Infest gives Lifestealer an easy way to escape should he get caught out by Earthshaker. And against carry Earthshaker, Aghanim's Scepter upgraded Infest can be used to disarm Earthshaker and attack him from within, rendering him unable to attack with Enchant Totem.

* Lifestealer's Rage renders him immune to all of Marci's disables and magic damage for a good duration.
* His passive Feast deals bonus damage based on the enemy's max health and heals for the same amount. As a tanky Strength hero, Marci's own strength will be her undoing as well.

* Feast is an effective tool against Centaur Warrunner, who generally has high health and low armor, and compensates the reflected damage of Retaliate.
* If activated, Rage can protect Lifestealer from Hoof Stomp, Double Edge, and Stampede.
Additional:
* Centaur Warrunner's active abilities cannot pierce magic immunity. Hoof Stomp's slow wind up can also be anticipated and negated with Rage.
* Lifestealer can offset Retaliate's damage return simply with Feast. Centaur's high strength gain and therefore big health pool makes him an ideal target to Feast on, especially in the late-game.

* Lifestealer is able to endure Undying, especially in the laning phase, where Undying is strongest. Feast can offset Decay's strength steal for its percentage lifesteal. Rage delays Undying from stealing strength and can help Lifestealer destroy Undying's Tombstone uninterrupted. As well, none of Undying's abilities pierce magic immunity.

* Laser blinds Bloodseeker, preventing him from getting last hits and denies during the laning stage and preventing him from finishing off enemies.
* Tinker always buys Boots of Travel, helping him escape Bloodseeker's early ganks.
* Tinker's heavy magical damage will burst down Bloodseeker during the early to mid game, as he has little health.
Additional:
* Laser can be very effective against Bloodrage as the damage will be amplified while the blind prevents Bloodseeker from landing hits.
* Keen Conveyance guarantees him escape from Rupture.

* Laser blinds Lone Druid, making his attacks miss.

* Feast makes it impossible to for Lifestealer to be culled with Culling Blade and also deals high damage to Axe due to his naturally high health.
* However, Berserker's Call and Counter Helix can pierce through the Rage, and if Axe has allies with him against Lifestealer, Lifestealer may go down very quickly.

* Heroes with powerful spammable abilities will prove problematic for Grimstroke as Ink Swell does not protect him from them: Zeus, Skywrath Mage, Tinker, Lina

* Any hero with a low HP pool is easy for Tinker to nuke down: Crystal Maiden, Enchantress, Gyrocopter, Lion, Riki, Techies, Terrorblade, Necrophos, Invoker.

* Rage grants immunity from Invoker's spells and can dispel most of the disables such as the armor loss from Forge Spirit and the constant stuns of Cold Snap.
Additional:
* Rage protects Lifestealer from all of Invoker's spells (except for Sun Strike).

* Any hero with a low HP pool is easy for Tinker to nuke down: Crystal Maiden, Enchantress, Gyrocopter, Lion, Riki, Techies, Terrorblade, Necrophos, Invoker.

* Heroes with good counter-push abilities to clear creep waves can hinder Jakiro's early pushing ability: Death Prophet, Sniper, Tinker, Windranger.

* Rage grants Lifestealer immunity to all of Jakiro's spells. Note: magic resistance will not dispel the attack speed slow effects from Dual Breath and Liquid Fire.

* Heroes with spell immunity-granting spells will render Phoenix useless against them, as Phoenix has almost no spell immunity-piercing ability, other than the stun at the end of Supernova: Lifestealer, Juggernaut.

* Heroes with burst damage of their own won't be afraid to go toe to toe with Void Spirit, like Ursa, Lifestealer, or Axe.

* Heroes who have most or all their abilities (damage or disable) unable to pierce spell immunity: Keeper of the Light, Lina, Lion, Zeus.

Additional:
* Rage protects Lifestealer from all of Lina's abilities. However, Lina can paritally counter this if played as Carry, a common role for Lina.
* Open Wounds from Aghanim's Shard can severely slow down Lina and allow Lifestealer and his allies to recover themselves by attacking her.
* Aghanim's Scepter upgraded Infest can be used to disarm Lina even if she is spell immune, rendering her unable to maximize the effect of her Fiery Soul and force her to use her abilities more often than intended. And Lina's only way to counter this is with Linken's Sphere

* Lifestealer with Rage and Infest
* Heroes that can remove the Track debuff with their skills:
* Abaddon with Aphotic Shield and Borrowed Time
* Huskar with Life Break
* Juggernaut with Blade Fury
* Legion Commander with Press the Attack
* Lifestealer with Rage and Infest
* Naga Siren with Mirror Image
* Omniknight with Heavenly Grace
* Oracle with Fortune's End and False Promise
* Phantom Lancer with Doppelganger
* Slark with Dark Pact
* Ursa with Enrage
* Weaver with Time Lapse
* Tidehunter with Kraken Shell when damage received reaches the threshold.

* Heroes who rely on basic attacks will suffer from Laser: Phantom Assassin, Wraith King, Huskar.

* Laser can be cast on a initiating Ursa, normally causing him to waste multiple Overpower attacks, forcing him to either Black King's Bar, or Enrage to protect himself.
* Ursa will probably carry a Linken's Sphere to counter Tinker's Laser. Popping it with Scythe of Vyse is actually preferable, due to Laser's high Pure damage.
* While Ursa is a common Blink Dagger carrier, but he otherwise has no way to close the gap, Baiting him into using his Blink, then blinking away, allows Tinker to easily kite Ursa.
* Enrage is generally how Ursa disengages, Due to Tinker's high maneuverability, he can follow him until it runs out. then burst him down with high magic damage.

* With Aghanim's Scepter upgraded Infest, Lifestealer can use it on enemy heroes to attack them and disarm them from inside, even if they are spell immune, which can give him the edge over the heroes he's weak against like Ursa, Phantom Assassin, Terrorblade or Troll Warlord.

* Heroes with good escape mechanisms are a nuisance to deal with in the early phase of the game: Slark, Lifestealer, Morphling

* Tinker has great map presence because of Keen Conveyance and Rearm, which means he can always teleport and defend towers whenever Nature's Prophet tries to push.
* Laser prevents Nature's Prophet from attacking. Additionally, even with Monkey King Bar, Nature's Prophet cannot hit towers and buildings during the effect.

* All Tinker's damage is magic/pure and completely ignores Timbersaw's Reactive Armor.
* Timbersaw very rarely builds Black King Bar, making him very vulnerable if Tinker builds Scythe of Vyse.

* The blind from Laser prevents Shadow Fiend from attacking for its duration, potentially preventing him from getting a kill.
* Scythe of Vyse can be used to prevent Shadow Fiend from casting Requiem of Souls.
* A combination of Tinker's abilities and his items (like the Dagon 5 and Ethereal Blade combo) can kill Shadow Fiend quickly.
Additional:
* During the laning stage Laser will reduce Shadow Fiend's last hits, preventing him from getting Necromastery souls.
* Shadow Fiend has low health and is vulnerable to Tinker's high magic burst.

* Rage negates Kunkka's X Marks the Spot.
* As a strength hero with high strength gain and very little armor, as well as low agility gain, Kunkka is vulnerable to Lifestealer's Feast and Open Wounds.

* All of Tinker's damage is magical and pure, which makes Cold Embrace a good setup for his nukes.
* Winter's Curse is very hard to cast on Tinker because he usually stays in the back-lines in team-fights. In turn, Tinker has mediocre attack damage and will contribute very little when he is cursed to attack an ally. He can also save his ally under Winter's Curse effect with Ethereal Blade and Defense Matrix.

* An Aghanim's Scepter upgraded Laser allows Tinker to blind Terrorblade and his illusions.
* Tinker deals incredible amounts of pure and magical damage with Laser and Heat-Seeking Missile combined with Rearm, which will ignore Terrorblade's armor and be devastating to his low health pool.
* Tinker is a hero who very often goes for Blink Dagger, and because Terrorblade has no disable to lock down Tinker, he will be unable to catch up with him nor to prevent him from escaping with Boots of Travel.
* Even if Terrorblade manages to catch up to Tinker, Tinker can simply teleport Terroblade away from him with Warp Flare provided by Aghanim's Shard, which can also weaken Terrorblade's attack range and cast range.
Additional:
* Tinker can single-handedly stop Terrorblade's early-push and quickly clear his illusions with Laser (especially with Aghanim's Scepter).
* Tinker has perfect tools to reveal Terrorblade from his illusions as well as to burst him down if he is low-health before he will be able Sunder.

* With Aghanim's Scepter upgraded Infest, Lifestealer can use it on enemy heroes to attack them and disarm them from inside, even if they are spell immune, which can give him the edge over the heroes he's weak against like Ursa, Phantom Assassin, Terrorblade or Troll Warlord.

* Heroes with wide AoE abilities will reveal Monkey King through Mischief: Necrophos, Phoenix, Alchemist, Earthshaker, Razor, Tinker, Leshrac, Queen of Pain

* Feast deals damage and heals Lifestealer based on the target's maximum HP, which is greatly effective against naturally high HP heroes such as Doom.
* Rage allows Lifestealer to become spell immune to negate the magical damage of Infernal Blade and Scorched Earth.
* Doom has no effective means of escape from Open Wounds and Ghoul Frenzy. This is particularly devastating in the laning stage, where Doom may have to play a much more passive, conservative play style as a result.

* All of Tinker's damage is magic/pure and completely ignores Enchantress's Untouchable. And Tinker's nukes can quickly decimate her small HP pool, sometimes even preventing Enchantress from even responding.
* As Enchantress relies solely on her primary attacks to deal damage, and rarely builds something to dispel it, Laser's Blind is particularly effective.
* However, Enchantress will probably build a Linken's Sphere against Tinker's Laser, so getting an additional disable is highly recommended.

* Tinker can break Magnus's Blink Dagger using March of the Machines and Heat-Seeking Missile, therefore delaying any initiation or making Magnus use Skewer or Force Staff to initiate. His {Ability ID:Defense Matrix|Tinker} will decrease the duration of Reverse Polarity and can also be cast on all of his teammates with {Ability ID:Rearm|Tinker}. Tinker usually gets his own Blink Dagger as well, which makes him harder to lock down unless Magnus commits Reverse Polarity only for Tinker.

* Feast deals damage and heals lifestealer based on the target max health. Because Spectre often emphasises on building stat items to increase her HP pool, lifestealer can deal a lot of damage to her and heal himself at the same time.
* Ghoul Frenzy slows target, which is bad for Spectre if she does not have Spectral Dagger ready.
* Spectre cannot response to infest if lifestealer choose to stay inside his high mobility allies to approach the backline. Rage's bonus movement speed and spell immunity make it even more frustrating.

* If Tinker can stay outside of Chronosphere, Laser can cause Faceless Void to miss all his attacks.
* Faceless Void has low health and strongly relies on Time Walk's healing factor to remain alive. Getting caught by Tinker with Scythe of Vyse will almost always spell a quick end for Void.
* Rearm ignores Time Dilation completely.

* The lifesteal of Feast scales accordingly to the max health of its target, which is effective against Pudge due to his high health and further health granted by stacks of Flesh Heap.
* Lifestealer can activate Rage to be spell immune, making Rot deal no damage.
* Pudge's plentiful health makes him an ideal target for Lifestealer's Aghanim's Shard ability, Open Wounds.

* Rage can protect Lifestealer from most of the Silencer's abilities with the exception of Global Silence, as it will still silence if cast while the target is magic immune. However, it will not work if Lifestealer is infesting a unit.
* Silencer is vulnerable to Open Wounds due to his lack of an innate escape.
* Against a carry Silencer, Aghanim's Scepter upgraded Infest can disarm him and allow Lifestealer to attack Silencer from within, even if Silencer is spell immune.
Additional:
* Rage can protect Lifestealer from most of the Silencer's abilities with the exception of Global Silence.
* If Lifestealer can Infest himself on any unit, he can literally avoid being affected by Global Silence.
* Against a carry Silencer, Aghanim's Scepter upgraded Infest can disarm him and allow Lifestealer to attack Silencer from within, even if Silencer is spell immune.
* Open Wounds from Aghanim's Shard can severely slow down Silencer, and allow Lifestealer and his team to heal themselves by attacking Silencer.

* Rage allows Lifestealer to freely attack Nyx Assassin and hunt him down if Vendetta is on cooldown. Nyx Assassin cannot counter Rage with Spiked Carapace because Rage gives Lifestealer spell immunity. And besides Vendetta, Nyx Assassin has no other way of dealing damage to Lifestealer while he is spell immune.
* Open Wounds from Aghanim's Shard allows Lifestealer to severely slow down Nyx Assassin while also allowing his team to recover themselves while attacking Nyx Assassin. Open Wounds can also fester and spread if Nyx Assassin takes enough damage that will trigger the spread while he is affected with Open Wounds.
* Infest combined with an ancient creep makes Nyx Assassin an easy target to surprise with Dust of Appearance or a Gem of True Sight. Aghanim's Scepter upgraded Infest can also allow Lifestealer to infest, disarm and freely attack Nyx Assassin from within. and Nyx Assassin cannot counter this with Spiked Carapace because Lifestealer is invulnerable while attacking the infested enemy hero from within.
* Overall, any attempt for Nyx Assassin to gank and kill Lifestealer will hurt Nyx Assassin more than Lifestealer.
Additional:
* Like with Juggernaut's Blade Fury, Rage allows Lifestealer to freely attack Nyx Assassin and hunt him down if Vendetta is on cooldown. Nyx Assassin cannot counter Rage with Spiked Carapace because Rage gives Lifestealer spell immunity. And besides Vendetta, Nyx Assassin has no other way of dealing damage to Lifestealer while he is spell immune.
* Open Wounds from Aghanim's Shard allows Lifestealer to severely slow down Nyx Assassin while also allowing his team to recover themselves while attacking Nyx Assassin. Open Wounds can also fester and spread if Nyx Assassin takes enough damage that will trigger the spread while he is affected with Open Wounds.
* Infest combined with an ancient creep makes Nyx Assassin an easy target to surprise with Dust of Appearance or a Gem of True Sight. And similarly to Juggernaut's Omnislash and Swiftslash from Aghanim's Scepter, Aghanim's Scepter upgraded Infest can also allow Lifestealer to infest, disarm and freely attack Nyx Assassin from within. And Nyx Assassin cannot counter this with Spiked Carapace because Lifestealer is invulnerable while attacking the infested enemy hero from within.
* Like with Juggernaut, any attempt for Nyx Assassin to gank and kill Lifestealer will hurt Nyx Assassin more than Lifestealer.

* With Feast and Rage, Lifestealer is nearly impossible for Clockwerk to bring down, and is the last hero Clockwerk wants to be trapped with in Power Cogs.

* Lifestealer's Rage negates Sand King's spells which do magical damage.

* Heroes with magic immune abilities can negate most of Visage's attacks like Pangolier and Lifestealer.