* Heroes who do not have nor rely on passive abilities make Nethertoxin much less effective: Clinkz, Pugna, Nature's Prophet, Dark Seer, Lycan, Tusk

Additional:
* Viper Strike can be countered through Snowball, wasting Viper's mana through his ultimate. It's Viper Strike's break is also useless because he has no passive abilties at all. And to make things worse, Viper Strike cannot disable Walrus PUNCH! because it's an auto-cast ability
* As Tusk is a natural Silver Edge wielder, he can use it to disable Viper's magic resistance from Corrosive Skin, and make him vulnreable to his other allies.

* Tusk with Snowball
* Heroes that can dodge Glimpse:
* Puck with Phase Shift
* Riki with Tricks of the Trade
* Phantom Lancer with Doppelganger
* Ember Spirit with Sleight of Fist and Activate Fire Remnant
* Chaos Knight with Phantasm
* Naga Siren with Mirror Image
* Tusk with Snowball
* Juggernaut with Omnislash
* Brewmaster with Primal Split
* Lifestealer with Infest
* Phoenix with Supernova

* Heroes with abilities that can pull Lina out of position can easily bring her to their team mates, like Batrider with Flaming Lasso, Pudge with Meat Hook and Vengeful Spirit with Nether Swap.

* She can easily cancel Wukong's Command with Nether Swap.
* Wave of Terror can also detect him while he's on the trees.
Additional:
* Wave of Terror grants flying vision over trees, and its wide effect can hit Monkey King and end Mischief.
* Nether Swap can easily cancel Wukong's Command by swapping him out of the circle.

* Tusk can Walrus Kick Monkey King from Wukong's Command, making his ultimate useless.

* Magic Missile can stun Chen and deal heavy damage to him.
* Wave of Terror weakens durability of Chen and his creeps.
* Nether Swap can be used to separate Chen away from his creeps, often to certain death from Vengeful Spirit's allies.

* Heroes that can easily bypass Chen's creeps to get to Chen: Riki, Tusk, Clinkz, Sniper, Slark, Phantom Assassin, Void Spirit, Storm Spirit, Ember Spirit, Earth Spirit, Spirit Breaker.

* Certain heroes can mess up with Pangolier's positioning and timing (especially if he intends to use Rolling Thunder during combat): Vengeful Spirit, Keeper of the Light, Huskar, Dark Seer

* Ice Shards can easily interfere with Rolling Thunder, making him stuck inside the arc and wasting his ultimate. Do not panic and use Shield Crash to get out of that position.
* Snowball helps Tusk and his allies follow a fleeing Pangolier, keep in mind that the Pangolier can always counter-initiate with his Rolling Thunder.
* Walrus PUNCH! deals heavy damage even during his Rolling Thunder.

* Heroes with catch to disrupt Sniper's positioning and deliver him into the enemies: Batrider, Disruptor, Pudge, Vengeful Spirit.

* Snowball allows Tusk to move himself and allies towards Sniper whilst invulnerable and hidden.
* His Ice Shards may also block pathing for Sniper as he has no means of moving through obstacles. In addition, Tag Team can hinder Sniper's escape.
Additional:
* Tusk alone or with his teammates can close Sniper's long range easily with Snowball, even wasting Shrapnel, ending with a very vulnerable Sniper.
* Walrus PUNCH!'s very high physical damage output can easily kill Sniper instantly due to his low health and armor.

* Heroes with strong channeling spells like Crystal Maiden's Freezing Field, Bane's Fiend's Grip, and Enigma's Black Hole can easily be interrupted from a long range by Nether Swap, assuming they don't have a Linken's Sphere.

* Snowball allows Tusk to easily cancel Freezing Field from a safe distance without putting himself in any danger.
* Walrus PUNCH! is most certainly a high enough damage nuke to easily kill off Crystal Maiden.
* Ice Shards can prevent the already immobile Crystal Maiden from escaping, making her an easy kill for either Tusk or a teammate.
Additional:
* Crystal Maiden's low health and armor make her an easy target for Walrus PUNCH!
* Tusk's Snowball can protect allies and cancel Freezing Field.
* Snowball and Walrus PUNCH! can interrupt Freezing Field.

* Heroes with strong channeling spells like Crystal Maiden's Freezing Field, Bane's Fiend's Grip, and Enigma's Black Hole can easily be interrupted from a long range by Nether Swap, assuming they don't have a Linken's Sphere.

Additional:
* Vengeful Spirit can interrupt Black Hole's channeling through Black King Bar by using Nether Swap from a safe distance.
* Vengeful Spirit's Level 25 Talent can make her Magic Missile pierce spell immunity, giving her another option to use in conjunction with Nether Swap to cancel Enigma's Black Hole channeling even through both, Black King Bar and Linken's Sphere.

* Walrus PUNCH! can interrupt Black Hole and it can pierce spell immunity and neither Black King Bar nor Linken's Sphere can protect Enigma from Walrus PUNCH! as Walrus PUNCH! is an auto-cast ability.
* In pretty much any phase of the game, Tusk's abilities can easily cancel Black Hole and disrupt Enigma's positioning.

* Heroes with high physical and magical damage alike are a huge hazard for Muerta, as they can deal serious damage to her even if she has Pierce the Veil active: Luna, Lina, Tusk, Broodmother, Shadow Fiend, Ember Spirit, Gyrocopter, Vengeful Spirit, Arc Warden, Medusa, Shadow Shaman.

* Heroes with high physical and magical damage alike are a huge hazard for Muerta, as they can deal serious damage to her even if she has Pierce the Veil active: Luna, Lina, Tusk, Broodmother, Shadow Fiend, Ember Spirit, Gyrocopter, Vengeful Spirit, Arc Warden, Medusa, Shadow Shaman.

* Heroes with strong channeling spells like Crystal Maiden's Freezing Field, Bane's Fiend's Grip, and Enigma's Black Hole can easily be interrupted from a long range by Nether Swap, assuming they don't have a Linken's Sphere.

* Heroes with hiding abilities can protect disabled allies: Outworld Destroyer, Shadow Demon, Tusk, Phoenix with Aghanim's Scepter.

Additional:
* Bane has low mobility and health, making him an easy target for Walrus PUNCH!
* Walrus PUNCH! can be used to cancel Fiend's Grip if he is not the target.

* With the exception of Magic Missile (unless the player takes the Level 25 Talent "Magic Missile Pierces Spell Immunity"), all of Vengeful Spirit's spells ignore Spell Immunity. This also makes her good against heroes with built-in Spell Immunity like Lifestealer or Juggernaut or heroes that tend to pick up Black King Bar, like Sven.

* Heroes with abilities that can save teammates are also effective such as Shadow Demon, Dazzle, Oracle, Bane, Pugna, Tusk, Winter Wyvern, Io, Underlord, Treant Protector and Keeper of the Light.

* Nether Swap can forcibly reposition Sharpshooter.

* With her Nether Swap, a well positioned Vengeful Spirit can save the life of a more important ally who gets caught in Chronosphere.
Additional:
* Nether Swap can save an ally from the Chronosphere.

* Snowball can protect Tusk and his teammates from a Spear of Mars' stun after an Arena of Blood, and with proper targeting, even bring them out of the Arena. This is especially noticeable in the earlier stages of the game before allies buy Black King Bar and rely on this less. Even during the late-game, Tusk can purchase a Blink Dagger to save allies that are caught before Black King Bars can be used by Blinking in and Snowballing out.
* Tag Team is a constant threat to Mars in-lane, as it deals significant damage and slow, making Bulwark slightly ineffective.
* It is worth noting that Ice Shards can be detrimental to Tusk's own team by creating terrain that Spear of Mars can latch on, though using it conservatively is a good enough solution in most cases.

* Nether Swap breaks one ally out of Soulbind, and can be used to redistribute the shared damage to Vengeful Spirit herself.

* Pugna's low health and reliance on channeled abilities make him very vulnerable to Tusk, although Pugna can win in a straight up 1v1 later in the game.

* Tag Team easily overwhelms Pudge, as he has low armor, which when combined with heroes with strong physical damage and Pudge's slow speed, it becomes for Pudge difficult to escape.
* Snowball can save a Dismembered ally and stop Pudge's Dismember.
* Walrus PUNCH! will removes a big chunk of Pudge's health and stun him.
* Pudge usually can't stand toe to toe against Tusk and his allies in the early game.

* Vengeful Spirit has two abilities to interrupt Death Ward, even through Black King Bar.

* Snowball can be used to save allies or himself during Venomous Gale and Poison Nova.
* Venomancer lacks mobility and has low base health, so he can be killed by Walrus PUNCH!

* Snowball and Ice Shards keep Drow Ranger down and preventing her from running away.
* Snowball also lets Tusk get to Drow Ranger and stop her Marksmanship bonus. It can also be to save allies affected by Gust.
* Tag Team allows Tusk to slow her down and land a killing blow on her.
* Walrus PUNCH! slows Drow Ranger and deals a huge amount of damage to her, due to her low health (and low armor without Marksmanship, since Tusk can quickly close the gap to Drow Ranger).

* Shadow Fiend's lack of mobility and low base health make him an easy target for early ganks.

* With Nether Swap, Vengeful Spirit can isolate one of the Meepos, making him an easier kill for the team.
* Her Magic Missile gives her an easy way to cancel Meepo's Poof, preventing isolated Meepos from fleeing.

* Huskar struggles against heroes that output high physical damage due to his low armor. Vengeful Spirit's Wave of Terror and Vengeance Aura help increase the physical damage of her team.

* Nether Swap gives Vengeful Spirit a way to save an ally from Clockwerk's Power Cogs.
* Magic Missile will interrupt Clockwerk trying to run down Vengeful Spirit's allies with Battery Assault.

* Walrus PUNCH! makes Legion Commander lose Duel easily, especially when she doesn't have Blade Mail. Tusk can also snowball dueled allies, preventing them from taking damage for a large portion of the duel's duration.

* Wave of Terror can reveal a Tinker attempting to hide in the trees and then Nether Swap and Magic Missile will both serve to interrupt/lock him down, should he attempt to town portal or reload.

* With her Nether Swap, Vengeful Spirit can save the life of an ally who gets caught with Flaming Lasso. Nether Swap also makes it highly dangerous for Batrider to attempt a lasso, as it can lead to his own demise far behind enemy lines.
* Wave of Terror's flying vision allows Vengeful Spirit to spot Batrider trying to close in on his target with Firefly.
Additional:
* Nether Swap breaks Flaming Lasso when used on ally and can break if used on Batrider.
* Vengeful Spirit can disable Batrider's Blink Dagger before a fight with Wave of Terror.

* Shadow Demon, Outworld Destroyer and Tusk can all save a Lasso'd teammate with their defensive spells.

* Heroes with abilities that can lock down Terrorblade and prevent him from using Sunder: Bane, Batrider, Earthshaker, Elder Titan, Faceless Void, Invoker, Legion Commander, Mars, Primal Beast, Riki, Shadow Shaman, Silencer, Vengeful Spirit, Void Spirit.

* Because Templar Assassin does not have escape potential in lane, any support hero with roaming potential and a Dust of Appearance can be great at shutting her down early game: Earth Spirit, Spirit Breaker, Tusk, Bounty Hunter, Riki, Warlock.

* Heroes that are able to slow Tiny's attack speed, like Tusk and Phoenix, will greatly limit his Physical damage output.

* Heroes with spell immunity or pseudo-blinks which provide invulnerability: Lifestealer, Juggernaut, Omniknight, Huskar, and Tusk have spells which allow them to easily escape Dream Coil.

* Heroes with disables that ignore spell immunity will render Phantom Assassin completely useless in teamfights throughout the game: Axe, Enigma, Vengeful Spirit, Doom, Bane, Beastmaster, Pudge, Medusa, Warlock.

* Heroes with long range abilities are also able to touch Zeus, such as Clockwerk, Kunkka, Puck, Skywrath Mage, Spirit Breaker, Tusk and others.

* Heroes that can easily bypass Io's allies to get to Io: Riki, Tusk, Clinkz, Sniper, Slark, Phantom Assassin, Void Spirit, Storm Spirit, Ember Spirit, Earth Spirit, Spirit Breaker, Lifestealer.

* With the exception of Magic Missile (unless the player takes the Level 25 Talent "Magic Missile Pierces Spell Immunity"), all of Vengeful Spirit's spells ignore Spell Immunity. This also makes her good against heroes with built-in Spell Immunity like Lifestealer or Juggernaut or heroes that tend to pick up Black King Bar, like Sven.

* With the exception of Magic Missile (unless the player takes the Level 25 Talent "Magic Missile Pierces Spell Immunity"), all of Vengeful Spirit's spells ignore Spell Immunity. This also makes her good against heroes with built-in Spell Immunity like Lifestealer or Juggernaut or heroes that tend to pick up Black King Bar, like Sven.

* Tusks damage/stun is enough to obliviate Storm Spirit before he can do anything.
* Tusk is a common Blink Dagger carrier, and once he reaches Level 18, Walrus PUNCH! deals roughly half of Storm Spirit's health alone, It also stuns for a long enough time for Tusk to Snowball Storm Spirit, stunning him even more, If that hasn't finished him off, the damage from Ice Shards probably will. Combined with Tag Team, which adds bonus damage to Tusks attacks, Storm Spirit is unlikely to survive Tusk initiating on him
* Walrus PUNCH is even more potent if he uses a Silver Edge instead
* However while Ball Lightning doesn't disjoint Snowball, if used before Tusk hits with Snowball, prevents the stun and damage from being applied

* Snowball negates Rupture and protects Tusk allies when Ruptured.