Venomancer
* 
Venomous Gale is a great ganking and farming skill.
* 
Plague Ward serves as a flexible ability for pushing, ganking, farming and scouting. The innate 
Poison Sting also works on the stolen Plague Ward with half the damage.
* 
Poison Nova, if stolen and cast, puts a huge damage-over-time debuff on the enemy team, even greater than Venomancer himself with the help of 
Arcane Supremacy.
* 
Spell Steal has a greater cast distance than the effect area of Poison Nova, allowing Rubick to steal the spell while staying at the back.
* 
Venomancer suffers from mana pool problems, while Rubick has relatively high intelligence gain and can cast the same set of spells at ease.
Additional:
* All of Venomancer's abilities are decent choices for Rubick's Spell Steal. Stealing Plague Wards makes them apply Poison Sting as well.
Luna
* 
Telekinesis allows Rubick and his team to coordinate a gank on Luna early on. And just like 
Aghanim's Shard upgraded 
Dismember, Aghanim's Shard upgraded Telekinesis can also allow Rubick to save an allied hero from being killed by Eclipse.
* 
Fade Bolt allows Rubick to harass Luna on lane and weaken her attack damage early on.
* Both, 
Lucent Beam and 
Eclipse are very useful for Rubick to steal with Spell Steal, Luna's only way to counter this is with Aghanim's Shard upgraded 
Moon Glaives. Rubick can also use them from further distances than Luna thanks to Arcane Supremacy that increases his cast range and when he gets 
Aghanim's Scepter.
* For the same reasons, Rubick makes a very powerful ally for Luna when they are in the same team.
Additional:
* Lucent Beam is a solid magic nuke with a stun.
* Aghanim's Shard upgraded Lucent Beam gives Rubick bonus damage whenever he uses it
* Eclipse can output massive damage if casted by 
Rubick.
* Rubick has a good chance to steal Eclipse since 
Luna has only two cast abilities.
* Aghanim's Scepter greatly increase the effectiveness of the ability, with more damage as well as extended cast range.
* For the same reasons, Rubick also makes a good ally for Luna when they are in the same team.
Venomancer
* Sniper can easily destroy Plague Ward from long range.
Luna
* Heroes that outrange Luna can be a problem for her: 
Drow Ranger, 
Sniper.
Venomancer
* In the laning stage, making illusions of Venomancer will turn his Poison Sting back at him, making for an easy gank at level one, and for later when your mid comes for ganks.
Luna
* 
Demonic Purge takes off Luna's superior mobility, removing the need for chasing her and allowing your team to reposition in team fights or escape when at low HP. If Shadow Demon has Aghanim's Scepter it will also take away glaive bounces and extra damage from Luna's passive. And Luna's commonly items Manta Style and Black King Bar does not work dispell to Demonic Purge
* Luna's illusions created by Disruption are very valuable with their Moon Glaives. These will effectively counter her pushing attempts and are painfully effective in team fights.
* Disruption can be used to save an ally from Eclipse.
* For the same reasons, Shadow Demon makes a very powerful ally for Luna when they are in the same team.
Additional:
* Demonic Purge takes off Luna's superior mobility, removing the need for chasing her and allowing your team to reposition in team fights or escape when at low HP. If Shadow Demon has Aghanim's Sceptre it will also take away glaive bounces and extra damage from Luna's passive.
* Luna's illusions created by Disruption are very valuable with their Moon Glaives. These will effectively counter her pushing attempts and are painfully effective in team fights.
* Disruption can be used to save an ally from Eclipse.
* For the same reasons, Shadow Demon is a very good ally for Luna when they are in the same team.
Luna
* Illusions and summons are double-edge sword type of matchup for Luna. On one hand, they can tank damage from Eclipse, but on the other hand, she can easily clear them before Eclipse with Moon Glaives. Examples include 
Spectre, 
Shadow Demon, 
Phantom Lancer, 
Naga Siren, 
Chaos Knight, 
Terrorblade) or bring other units into the fight (such as 
Nature's Prophet, 
Lone Druid, 
Chen, 
Enchantress, 
Meepo and 
Arc Warden).
Venomancer
* 
Dark Pact can dispel Venomous Gale and Poison Sting.
* 
Shadow Dance allows Slark heightened regeneration when out of vision making DoTs effects less threatening.
Luna
* Shadow Dance prevents Luna from damaging Slark, and together with 
Silver Edge he can easily chase her or escape from her.
* Luna has no way to escape from 
Pounce's leash.
* For the same reasons, Slark makes a very powerful ally for Luna when they are in the same team.
Additional:
* Luna's lack of mobility and escape abilities makes her easily to gank for Slark.
* Shadow Dance helps avoid all the damage from Eclipse.
* For the same reasons, Slark makes a very powerful ally for Luna when they are in the same team.
Luna
* With 
Dust of Appearance, Luna will be able to use Eclipse on invisible heroes. Be mindful that 
Slark is exception because he'll be able to remove the debuff with Dark Pact.
Venomancer
* Heroes that deal damage over time will also fail to bring down Abaddon and his allies, such as 
Huskar, Venomancer, or 
Phoenix.
Additional:
* 
Borrowed Time & 
Aphotic Shield can dispel Venomous Gale and Poison Sting.
Luna
* Every hero that can withstand or prevent Eclipse at level 7: 
Juggernaut, 
Riki, 
Clockwerk, Drow Ranger, 
Abaddon, 
Faceless Void, 
Weaver, 
Outworld Destroyer.
Venomancer
* Any hero that can outrange Plague Ward can neutralize them without putting themselves at risk of receiving Poison Sting: Arc Warden, Chen, 
Clinkz, Drow Ranger, 
Lina, 
Mirana, Nature's Prophet, 
Pugna and Sniper.
* Special mention to heroes that outrange Plague Ward after obtaining talents that increase attack range.
Luna
* Every hero that can withstand or prevent Eclipse at level 7: Juggernaut, Riki, Clockwerk, Drow Ranger, Abaddon, Faceless Void, Weaver, Outworld Destroyer.
Venomancer
* Squishy heroes or heroes without hard disables or silences: Shadow Demon, 
Shadow Fiend, Venomancer, 
Ancient Apparition etc.
Luna
* Escape-type carries: Slark, 
Storm Spirit, Weaver.
Venomancer
* Heroes with damage-over-time abilities easily allow Bristleback to turn his back in order to proc 
Bristleback continuously and to massively reduce to damage dealt to him: Arc Warden, Venomancer, Luna.
Luna
* Heroes with damage-over-time abilities easily allow Bristleback to turn his back in order to proc Bristleback continuously and to massively reduce to damage dealt to him: Arc Warden, Venomancer, Luna.
Additional:
* 
Quill Spray and Bristleback harass Luna more efficiently than she does with Lucent Beam.
* Bristleback helps return a lot of damage to Luna’s team if she uses her nukes on him and he has his back to her.
* 
Viscous Nasal Goo and 
Warpath are enough to outrun a speedy Luna.
* Bristleback tends to be a frequent carrier of 
Crimson Guard and 
Eternal Shroud, which are good protection from Moon Glaives and Eclipse.
* For the same reasons, Bristleback makes a very powerful ally for Luna when they are in the same team.
Luna
* Should Luna choose to buy 
Manta Style, Medusa will be able to kill illusions from them with 
Split Shot and 
Mjollnir, which is a common item on Medusa.
* 
Mystic Snake allows Medusa to easily harass Luna and steal mana from her, preventing Luna from retaliating with Lucent Beam.
* Medusa can survive Eclipse thanks to 
Mana Shield, which can cause Luna to struggle greatly in bursting down Medusa and force her to buy 
Diffusal Blade and it's upgrade 
Disperser.
* Even with 
Black King Bar, Medusa's 
Stone Gaze will still be able to disable Luna, which could even discourage her from counter-initiating with Eclipse.
* For the same reasons, Medusa makes a very powerful ally for Luna when they are in the same team.
Additional:
* Should Luna choose to buy Manta Style, Medusa will be able to kill illusions from them with Split Shot and Mjollnir, which is a common item on Medusa.
* Mystic Snake allows Medusa to easily harass Luna and steal mana from her, preventing Luna from retaliating with Lucent Beam.
* Medusa can survive Eclipse thanks to Mana Shield, and since Luna is not a hero that often goes for Diffusal Blade, she will struggle greatly in bursting down Medusa.
* Even with Black King Bar, Medusa's Stone Gaze will still be able to disable Luna, which could even discourage her from counter-initiating with Eclipse.
* For the same reasons, Medusa makes a very powerful ally for Luna when they are in the same team.
Venomancer
* Venomancer is a low health hero and low range hero who is easy to harass with Ion Shell on a creep in the early game.
* Venomancer depends entirely on all his slows to keep distance or chase, but since Surge ignores slows, it is nearly impossible for Venomancer to hunt or run away from Dark Seer or his surged teammates.
Luna
* 
Burrowstrike allows Sand King to escape from Eclipse or to close the gap on Luna and finish her off.
* 
Sand Storm allows Sand King to harass Luna more efficiently than she does with Lucent Beam, as it makes him invisible for it's duration and while in it, rendering him safe from both, Lucent Beam and Eclipse and forcing Luna to buy Dust of Appearance more often.
* 
Caustic Finale allows Sand King to deal serious damage to both, Luna and her allies, which is especially hazardous in laning stage as Luna's attack range is short.
* 
Epicenter combined with Burrowstrike and Sand Storm can often kill Luna before she can do anything because of her low health and strength gain.
* Overall, Sand King forces Luna to play more defensively instead of offensively, and for the same reasons, Sand King makes a very powerful ally for Luna when they are in the same team.
Additional:
* Burrowstrike allows Sand King to escape from Eclipse or to close the gap on Luna and finish her off.
* Sand Storm allows Sand King to harass Luna more efficiently than she does with Lucent Beam, as it makes him invisible for it's duration and while in it, rendering him safe from both, Lucent Beam and Eclipse and forcing Luna to buy Dust of Appearance more often.
* Caustic Finale allows Sand King to deal serious damage to both, Luna and her allies, which is especially hazardous for Luna during the laning stage as Luna's attack range is short.
* Epicenter combined with Burrowstrike and Sand Storm can often kill Luna before she can do anything because of her low health and strength gain.
* Overall, Sand King forces Luna to play more defensively instead of offensively, and for the same reasons, Sand King makes a very powerful ally for Luna when they are in the same team.
Luna
* Because of her low range, Luna cannot easily destroy 
Healing Ward.
* Both 
Blade Fury and 
Omnislash are direct counters to Eclipse, offering Juggernaut spell immunity and invulnerabilty. Therefore, Luna will need assistance in taking down Juggernaut as going solo will not be successful.
* For the same reasons, Juggernaut makes a very powerful ally for Luna when they are in the same team.
Luna
* Despite Ancient Apparition's fragileness, he can easily harass Luna on lane with 
Chilling Touch due to it's high range and damage. This can get even worse if Ancient Apparition buys Aghanim's Scepter and combines it with items that can give him bonus attack damage and attack speed.
* Chilling Touch combined with 
Ice Vortex can make it difficult for Luna to escape from 
Cold Feet
* 
Ice Blast can nullify any healing Luna receives and any attempt for her to save herself with 
Satanic, even through Black King Bar.
* For the same reasons, Ancient Apparition makes a very powerful ally for Luna when they are in the same team.
Luna
* Even though Luna can easily kill Jakiro in few strikes, he can also do the same to her is she is not careful.
* 
Dual Breath and 
Liquid Fire allow Jakiro to harass Luna more efficiently than she can harass Jakiro with her Lucent Beam.
* Jakiro can save his allies from Luna during her attempts to use Eclipse by casting 
Ice Path on Luna.
* Aghanim's Scepter upgraded 
Macropyre can deal pure damage-over-time and pierce spell immunity, which can make it very hard for Luna to be in teamfights without suffering too many damage.
* For the same reasons, Jakiro makes a very powerful ally for Luna when they are in the same team.
Additional:
* Even though Luna can easily kill Jakiro in few strikes, he can also do the same to her is she is not careful.
* Dual Breath and Liquid Fire allow Jakiro to harass Luna more efficiently than she can harass Jakiro with her Lucent Beam.
* Jakiro can save his allies from Luna during her attempts to use Eclipse by casting Ice Path on Luna.
* Aghanim's Scepter upgraded Macropyre can deal pure damage-over-time and pierce spell immunity, which can make it very hard for Luna to be in teamfights without suffering too many damage.
* For the same reasons, Jakiro makes a very powerful ally for Luna when they are in the same team.
Luna
* Primal Beast has a massive healthpool making it very difficult to get through it with a nuke such as Eclipse or Lucent Beam.
* Primal Beast is faster than Luna, as one of her main ways to escape danger, is very problematic for her in the laning stage especially.
* His ultimate goes through debuff immunity, making Luna's Black King Bar less effective.
* Primal Beast commonly buys 
Blade Mail which is a big problem for a single target bursting hero like Luna.
Luna
* Zeus's highly damaging nuke spells with low cooldowns is not something Luna can go against, though Luna can win against Zeus in late game.
* 
Thundergod's Wrath can be used before a fight to harm Luna before she activates Black King Bar, reducing her survivability for that fight.
* For the same reasons, Zeus makes a very powerful ally for Luna when they are in the same team.
Venomancer
* Venomancer's damage-over-time abilities are easier to heal through with numerous Shadow Waves than other types of damage, and it's simple to time a Shallow Grave until the last possible second to save a teammate from them.
Venomancer
* Snowball can be used to save allies or himself during Venomous Gale and Poison Nova.
* Venomancer lacks mobility and has low base health, so he can be killed by Walrus PUNCH!
Venomancer
* Fortune's End and False Promise easily dispel many crippling debuffs, such as Venomancer's Venomous Gale, or 
Skywrath Mage's 
Ancient Seal.
Additional:
* 
Fortune's End can dispel Venomous Gale and Poison Sting from allies.
* 
Fate's Edict grants 100% magic resistance to target, inhibiting the damage from Venomancer abilities.
Luna
* All assassin-type carries in a one against one situation: Meepo, 
Phantom Assassin, Riki, 
Ursa. Luna's only chances are that she buys 
Ethereal Blade or Black King Bar to gain a slight edge against them, or both items if necessary.
Luna
* Every hero that can withstand or prevent Eclipse at level 7: Juggernaut, Riki, Clockwerk, Drow Ranger, Abaddon, Faceless Void, Weaver, Outworld Destroyer.
Venomancer
* Any hero that can outrange Plague Ward can neutralize them without putting themselves at risk of receiving Poison Sting: Arc Warden, Chen, Clinkz, Drow Ranger, Lina, Mirana, Nature's Prophet, Pugna and Sniper.
* Special mention to heroes that outrange Plague Ward after obtaining talents that increase attack range.
Luna
* Every hero that can withstand or prevent Eclipse at level 7: Juggernaut, Riki, Clockwerk, Drow Ranger, Abaddon, Faceless Void, Weaver, Outworld Destroyer.
Luna
* A couple of long-range heroes with excellent laning like Mirana, Lina, 
Necrophos, 
Death Prophet. The key to success is sticking together and attacking Luna whenever she enters the range, without even giving Luna a chance to retaliate. Multiple long-range heroes is a reason to pick another hero.
Luna
* Escape-type carries: Slark, Storm Spirit, Weaver.
Venomancer
* Vulnerable spellcasters with no escape mechanisms are easy targets for Huskar: 
Lich, 
Crystal Maiden, 
Silencer, 
Keeper of the Light, Venomancer, etc.
Additional:
* Huskar can easily regenerate lost health from DoT spells through 
Berserker's Blood rendering them ineffective
* Venomancer has little armor and mobility, and rarely builds Linken's Sphere, so he is quite vulnerable to 
Life Break.
Venomancer
* Teleportation allows Natures Prophet to save himself from the damage over time of Venomous Gale, Poison Sting and Poison Nova.
* Plague Wards can be destroyed with Nature's Prophet's Treants.
Luna
* Heroes that create illusions: Spectre, Shadow Demon, Phantom Lancer, Naga Siren, Chaos Knight, Terrorblade) or bring other units into the fight (such as Nature's Prophet, Lone Druid, Chen, Enchantress, Meepo and Arc Warden) can cause Eclipse to strike the illusions/summons unintentionally. However, in many cases Moon Glaives can resolve this issue and eliminate them before activating Eclipse, but that will require lots of farming for right-click items.
Luna
* Moon Glaives and 
Lunar Blessing help Luna quickly kill Nature's Prophet's treants.
* Luna can easily cancel Teleportation with her Lucent Beam.
* Even though Nature's Prophet can evade all of Luna's abilities with 
Shadow Blade, a smart Luna will always buy Dust of Appearance to provide vision on Shadow Fiend to her and her team.
Additional:
* Moon Glaives and Lunar Blessing help Luna quickly kill Nature's Prophet's treants. Aghanim's Shard upgraded Moon Glaives can also reduce damage Nature's Prophet will inflict on Luna while they are active.
* Luna can easily cancel Teleportation with her Lucent Beam.
* Even though Nature's Prophet can evade all of Luna's abilities with Shadow Blade, a smart Luna will always buy Dust of Appearance to provide vision on Nature's Prophet to her and her team.
Luna
* Hard-hitters who relies mostly on raw stats or good passive and therefore make a perfect target for 
Dark Portrait: Naga Siren, Faceless Void, Terrorblade, Luna, 
Anti-Mage
Luna
* Heroes that can keep Luna locked down for a long time can be a threat (she is very item and spell dependent): Faceless Void, 
Legion Commander, 
Doom.
Venomancer
* Voodoo Restoration heals to counter damage over time of Poison Nova and Poison Sting.
Luna
* Luna can easily cancel channeling spells with Lucent Beam and 0.25s Eclipse Lucent Ministun talent for Eclipse, she can also buy 
Abyssal Blade in case they decide to buy Black King Bar: 
Enigma's 
Black Hole, 
Witch Doctor's 
Death Ward, 
Shadow Shaman's 
Shackles, 
Lion's 
Mana Drain, 
Bane's 
Fiend's Grip, 
Pudge's Dismember, Crystal Maiden's 
Freezing Field, Pugna's 
Life Drain, 
Dawnbreaker's 
Solar Guardian, and Naga Siren's 
Reel In from Aghanim's Scepter.
Additional:
* Lucent Beam interrupts Death Ward from a decent range.
* With Dust of Appearance, Eclipse kills Witch Doctor during Death Ward, even through 
Glimmer Cape.
Luna
* Even with Black King Bar, Pudge's 
Meat Hook and Dismember can still disable Luna for a fairly long time.
* Many stacks of 
Flesh Heap will make it difficult for Luna to burst down Pudge with Eclipse. Aghanim's Shard upgraded Dismember can also allow Pudge to save an allied hero from being killed by Eclipse.
* Bear in mind, however, that Luna can cancel Dismember if some of her allies are targets. Which may force Pudge to buy Black King Bar earlier.
* For the same reasons, Pudge makes a very powerful ally for Luna when they are in the same team.
Luna
* Luna can easily cancel channeling spells with Lucent Beam and 0.25s Eclipse Lucent Ministun talent for Eclipse, she can also buy Abyssal Blade in case they decide to buy Black King Bar: Enigma's Black Hole, Witch Doctor's Death Ward, Shadow Shaman's Shackles, Lion's Mana Drain, Bane's Fiend's Grip, Pudge's Dismember, Crystal Maiden's Freezing Field, Pugna's Life Drain, Dawnbreaker's Solar Guardian, and Naga Siren's Reel In from Aghanim's Scepter.
Luna
* Even though Luna can clear Phantom Lancer's illusions with Moon Glaives, Phantom Lancer can create too many illusions to tank Luna's Eclipse and for Luna to handle overall.
* 
Doppelganger can be used to dodge a number of Lucent Beams during Eclipse.
* Phantom Lancer can chase Luna effectively regardless of her high movement speed thanks to 
Phantom Rush and 
Spirit Lance.
* Luna's low health pool is easily exploited by the sheer damage output from Phantom Lancer's illusions. Additionally, Phantom Lancer can often create more illusions for Luna to handle.
* For the same reasons, Phantom Lancer makes a very powerful ally for Luna when they are in the same team.
Luna
* Illusions and summons are double-edge sword type of matchup for Luna. On one hand, they can tank damage from Eclipse, but on the other hand, she can easily clear them before Eclipse with Moon Glaives. Examples include Spectre, Shadow Demon, Phantom Lancer, Naga Siren, Chaos Knight, Terrorblade) or bring other units into the fight (such as Nature's Prophet, Lone Druid, Chen, Enchantress, Meepo and Arc Warden).
Venomancer
* Any hero that can outrange Plague Ward can neutralize them without putting themselves at risk of receiving Poison Sting: Arc Warden, Chen, Clinkz, Drow Ranger, Lina, Mirana, Nature's Prophet, Pugna and Sniper.
* Special mention to heroes that outrange Plague Ward after obtaining talents that increase attack range.
Luna
* Heroes that create illusions: Spectre, Shadow Demon, Phantom Lancer, Naga Siren, Chaos Knight, Terrorblade) or bring other units into the fight (such as Nature's Prophet, Lone Druid, Chen, Enchantress, Meepo and Arc Warden) can cause Eclipse to strike the illusions/summons unintentionally. However, in many cases Moon Glaives can resolve this issue and eliminate them before activating Eclipse, but that will require lots of farming for right-click items.
Luna
* Luna's Moon Glaives allow her to clear Arc Warden's 
Tempest Double.
* Luna's short range and fast movement speed allow her to fight Arc Warden inside his 
Magnetic Field.
Additional:
* Luna's Moon Glaives allow her to clear Arc Warden's Tempest Double.
* Luna's short range and fast movement speed allow her to fight Arc Warden inside his Magnetic Field.
Venomancer
* Heroes rely on their debuff to control the opponent will have a hard time against Press the Attack: Venomancer, 
Earth Spirit, 
Ogre Magi
Additional:
* 
Press the Attack dispels Venomous Gale and Poison Sting from Legion Commander or her teammates.
* Venomancer is an ideal target for 
Duel due to his lack of mobility and low starting health.
Luna
* Heroes that can keep Luna locked down for a long time can be a threat (she is very item and spell dependent): Faceless Void, Legion Commander, Doom.
Luna
* A well-timed Eclipse before a Duel usually prevents Legion Commander from winning Duels, if Luna is the target.
* Meanwhile, when Luna is not a target, Eclipse and Lucent Beam can also help an ally win a Duel against Legion Commander.
* However, skilled Legion Commander will always buy a Black King Bar to block Eclipse and Lucent Beam or Aghanim's Scepter to reduce it's damage.
Additional:
* A well-timed Eclipse before a Duel usually prevents Legion Commander from winning Duels if Luna is the target. Luna can also buy 
Linken's Sphere to block Duel.
* Meanwhile, when Luna is not a target, Eclipse and Lucent Beam can also help an ally win a Duel against Legion Commander.
* Bear in mind, however, that skilled Legion Commander will always buy a Black King Bar to block Eclipse and Lucent Beam or Aghanim's Scepter to reduce their damage.
Venomancer
* Any hero that can outrange Plague Ward can neutralize them without putting themselves at risk of receiving Poison Sting: Arc Warden, Chen, Clinkz, Drow Ranger, Lina, Mirana, Nature's Prophet, Pugna and Sniper.
* Special mention to heroes that outrange Plague Ward after obtaining talents that increase attack range.
Luna
* A couple of long-range heroes with excellent laning like Mirana, Lina, Necrophos, Death Prophet. The key to success is sticking together and attacking Luna whenever she enters the range, without even giving Luna a chance to retaliate. Multiple long-range heroes is a reason to pick another hero.
Luna
* Even though Luna is the kind of hero that Mirana can handle due to 
Moonlight Shadow rendering her safe from Eclipse with Moonlight Shadow, smart Luna can buy Dust of Appearance, allowing her to provide vision on her to her team, and possibly, kill Mirana.
* Luna's high movement speed allows her to evade 
Sacred Arrow, giving Mirana difficulties in hitting her with it.
* Aghanim's Scepter upgraded Eclipse combined with Dust of Appearance allows Luna to cast it on a hero that is struck by Sacred Arrow and/or after Mirana jumps in with 
Leap.
Additional:
* Even though Luna is the kind of hero that Mirana can handle due to Moonlight Shadow rendering her safe from Eclipse with Moonlight Shadow, smart Luna can buy Dust of Appearance, allowing her to provide vision on her to her team, and possibly, kill Mirana.
* Luna's high movement speed allows her to evade Sacred Arrow, giving Mirana difficulties in hitting her with it.
* Aghanim's Scepter upgraded Eclipse combined with Dust of Appearance allows Luna to cast it on a hero that is struck by Sacred Arrow and/or after Mirana jumps in with Leap.
Venomancer
* Sunder can prevent Terrorblade's or an ally's death by swapping health, making damage-over-time abilities inefficient. Heroes that rely on damage-over-time abilities like Venomancer and Huskar will have a hard time against Sunder.
Additional:
* 
Reflection illusion will apply Poison Sting back towards Venomancer.
* 
Conjure Image and 
Metamorphosis will make quick work of Plague Wards.
* While ticking down from Poison Nova, Terrorblade can wait until the last possible moment to 
Sunder a target, either friend or foe.
Luna
* Heroes that create illusions: Spectre, Shadow Demon, Phantom Lancer, Naga Siren, Chaos Knight, Terrorblade) or bring other units into the fight (such as Nature's Prophet, Lone Druid, Chen, Enchantress, Meepo and Arc Warden) can cause Eclipse to strike the illusions/summons unintentionally. However, in many cases Moon Glaives can resolve this issue and eliminate them before activating Eclipse, but that will require lots of farming for right-click items.
Luna
* If carefully timed, Aghanim's Scepter upgraded Eclipse combined with 0.2s Eclipse Lucent Ministun talent can quickly finish off Terrorblade before he can get a chance to save himself with Sunder due to its high magical damage as long as Terrorblade has no Black King Bar.
* Moon Glaives allows Luna to clear Terrorblade's illusions from both, Conjure Image and Manta Style, this can be particularly advantegous for Luna if she has Manta Style. Just bear in mind, however, that Reflection can be used to turn Moon Glaives against Luna during laning phase.
* Luna very often builds Satanic and Black King Bar, which allows it either to protect herself from Sunder or nullify it's effects.
* Luna can also buy 
Monkey King Bar to help her deal with Terrorblade's high armor, which is a common item on Luna.
Additional:
* If carefully timed, Aghanim's Scepter upgraded Eclipse can quickly finish off Terrorblade before he can get a chance to save himself with Sunder due to its high magical damage if Terrorblade has no Black King Bar available to use.
* Moon Glaives allows Luna to clear Terrorblade's illusions from both, Conjure Image and Manta Style, this can be particularly advantegous for Luna if she has Manta Style. Just bear in mind, however, that Reflection can be used to turn Moon Glaives against Luna during laning phase. Aghanim's Shard upgraded Moon Glaives can be used to reduce damage Luna will take from Terrorblade and his illusions while also clearing waves of them and damaging Terrorblade if he is too close to Luna.
* Luna very often bulds Satanic and Black King Bar as well as it's alternative item Linken's Sphere, which allows her either to protect herself from Sunder or nullify it's effects.
* Luna can also buy Monkey King Bar to help her deal with Terrorblade's high armor, which is a common item on Luna. Likewise Luna can also buy 
Revenant's Brooch or 
Gleipnir whose attacks can also ignore Terrorblade's high armor.
Venomancer
* Similar to Night Stalker, Venomancer can simultaneously scout Magnus hiding in trees and put Blink Dagger on cooldown with Plague Ward, which gives Magnus problems when trying to blink in and initiate.
Additional:
* Venomancer can simultaneously scout Magnus hiding in trees and putting 
Blink Dagger on cooldown with Plague Wards, which makes Magnus real problems to blink and initiate.
Luna
* If Luna can use Eclipse in anticipation, Magnus will be killed before he can even manages to cast 
Reverse Polarity.
* Aghanim's Scepter upgraded Eclipse is a very good counter-initiation tool against Magnus when he casts Reverse Polarity, granted as long as Luna can cast it from safe distance.
Venomancer
* Venomancer's slows and magical damage-over-time works well against Earthshaker's which completes lack of mobility.
* Plague Wards are useful for slowing and kitting down Earthshaker, revealing him from initiating and re-initiating and putting his Blink Dagger on cooldown if Venomancer has vision over Earthshaker.
Additional:
* Earthshaker can be kited by Venomancer's slows, which is lack of mobility.
* Plague Wards is very useful for slowing and kitting down Earthshaker, revealing him from initiating and re-initiating and putting his Blink Dagger on cooldown.
Luna
* Luna's Lucent Beams and Eclipse will prevent Earthshaker from initiating or re-initiating.
* Aghanim's Scepter upgraded Eclipse can be used to counter-initiate against Earthshaker after he uses Aghanim's Scepter upgraded 
Enchant Totem.
* Skilled Luna can buy either {I|Gleipnir
Additional:
* Luna's Lucent Beams and Eclipse will prevent Earthshaker from initiating or re-initiating.
* Aghanim's Scepter upgraded Eclipse can be used to counter-initiate against Earthshaker after he uses Aghanim's Scepter upgraded Enchant Totem.
* Skilled Luna can buy either {I|Gleipnir
Venomancer
* Venomancer's magical damage-over-time poisons greatly reduce Bounty Hunter's mobility.
* Venomous Gale, combined with Plague Wards and Poison Nova with True Sight items can allow Venomancer and his teammates to gank Bounty Hunter while he is roaming alone.
Luna
* Even though Luna is the kind of hero that Bounty Hunter can handle due to Shadow Walk rendering him safe from Eclipse, smart Luna will always buy Dust of Appearance, allowing her to provide vision on him to her team, and possibly, kill Bounty Hunter with Eclipse.
Venomancer
* Venomous Gale, Poison Sting and Poison Nova deal damage over time and will chip away at Gravekeeper's Cloak in addition to slowing an already sluggish hero.
* Venomancer's normal attacks deal Poison Sting and will chip away at Gravekeeper's Cloak.
Luna
* Moon Glaives is very effective against Visage because not only it can easily destroy Visage's Familiars, but can also remove one instance of Gravekeeper's Cloak upon each hit to Visage, leaving him susceptible to damage.
* Once Visage's Familiars are picked off and all instances of Gravekeeper's Cloak are removed, Luna will be able to easily kill Visage with Eclipse.
Additional:
* Moon Glaives is very effective against Visage because not only it can easily destroy Visage's Familiars, but can also remove one instance of Gravekeeper's Cloak upon each hit to Visage, leaving him susceptible to damage.
* Once Visage's Familiars are picked off and all instances of Gravekeeper's Cloak are removed, Luna will be able to easily kill Visage with Eclipse.
Venomancer
* Heroes that commonly attack ethereal units will not have any problems against Muerta's Pierce The Veil: 
Tinker, 
Jakiro, Lina, Luna, Pugna or Ogre Magi, Enigma, 
Batrider, 
Techies, 
Broodmother, Dawnbreaker, Shadow Shaman, Bane, Tinker, Venomancer, Arc Warden.
Luna
* Lucent Beam can be used to harass Muerta in lane.
* Luna's high movement speed can make it difficult for Muerta to hit her with 
Dead Shot and keep her trapped in 
The Calling.
* 
Pierce the Veil will not save Muerta from Luna at all. Instead, it will sentence her to death as it will amplify the magical damage from both, Lucent Beam and Eclipse, potentially turning Muerta's most powerful ability against her. Aghanim's Scepter upgraded Eclipse can also be used to counter-initiate against Muerta.
* Luna can use Aghanim's Shard upgraded Moon Glaives to reduce all the damage Muerta inflicts on Luna while also damaging Muerta if she is too close to Luna. Bear in mind, however, Aghanim's Shard upgraded Moon Glaives cannot damage Muerta while she is under effects of Pierce the Veil.
* As Luna naturally buys Black King Bar, she will be able to defend herself from Muerta's abilities. Luna can also buy Revenant's Brooch to attack Muerta even through Pierce the Veil.
* Overall, most of the attempts for Muerta to gank and kill Luna will hurt Muerta more than Luna.
Additional:
* Lucent Beam can be used to harass Muerta in lane.
* Luna's high movement speed can make it difficult for Muerta to hit her with Dead Shot and keep her trapped in The Calling.
* Pierce the Veil will not save Muerta from Luna at all. Instead, it will sentence her to death as it will amplify the magical damage from both, Lucent Beam and Eclipse, potentially turning Muerta's most powerful ability against her. Aghanim's Scepter upgraded Eclipse can also be used to counter-initiate against Muerta until Muerta buys Black King Bar.
* Luna can use Aghanim's Shard upgraded Moon Glaives to reduce all the damage Muerta inflicts on Luna while also damaging Muerta if she is too close to Luna. Bear in mind, however, Aghanim's Shard upgraded Moon Glaives cannot damage Muerta while she is under effects of Pierce the Veil as they deal physical damage.
* As Luna naturally buys Black King Bar, she will be able to defend herself from Muerta's abilities. Luna can also buy Revenant's Brooch to attack Muerta even through Pierce the Veil.
* Overall, most of the attempts for Muerta to gank and kill Luna will hurt Muerta more than Luna.
Venomancer
* Venomancer's magical damage-over-time poisons will constantly put Tree Dance on cooldown, greatly diminishing Monkey King's mobility.
* Venomous Gale and Poison Nova will hit Monkey King when he is perched on a tree, or disguised with Mischief.
* However, Venomancer is also easily ganked by Monkey King if caught by surprise.
Additional:
* Venomancer's magical damage-over-time poisons putting 
Tree Dance on cooldown, greatly diminishing Monkey King's mobility.
* Venomous Gale and Posion Nova will hit Monkey King when he is perched on a tree, or disguised by 
Mischief.
Luna
* Heroes who are melee but cannot fight back against Eclipse will really struggle with Luna: 
Monkey King, 
Alchemist, 
Timbersaw.
Venomancer
* Heroes who rely on damage over time as Spiked Carapace can block and reflect only one instance of damage: Jakiro, 
Viper, Venomancer, Huskar, 
Ember Spirit, 
Dark Seer, 
Sand King, Doom, Dawnbreaker. However, this also means they are easily stunned.
Luna
* Even though Nyx Assassin can easily kill Luna with his high burst damage, Luna can also do the same to him if he is not careful.
* Lucent Beam can deal a fair amount of damage to Nyx Assassin if he has no 
Spiked Carapace available to use. Although Luna should be patient using Lucent Beam on Nyx Assassin when he uses Spiked Carapace.
* As Luna commonly buys Black King Bar, she can use it to freely attack Nyx Assassin whenever he tries to defend himself with Spiked Carapace during teamfights. Luna can also buy 
Eye of Skadi and Manta Style to survive Nyx Assassin's burst damage and distract him.
* Though 
Vendetta can deal serious damage to Luna and avoid Eclipse, smart Luna will always buy Dust of Appearance to provide vision on Nyx Assassin to her and her team.
Additional:
* Even though Nyx Assassin can easily kill Luna with his high burst damage, Luna can also do the same to him if he is not careful.
* Lucent Beam can deal a fair amount of damage to Nyx Assassin if he has no Spiked Carapace available to use. Although Luna should be patient using Lucent Beam on Nyx Assassin when he uses Spiked Carapace.
* As Luna commonly buys Black King Bar, she can use it to freely attack Nyx Assassin whenever he tries to defend himself with Spiked Carapace during teamfights. Luna can also buy Eye of Skadi and Manta Style to survive Nyx Assassin's burst damage and distract him.
* Though Vendetta can deal serious damage to Luna and avoid Eclipse, smart Luna will always buy Dust of Appearance to provide vision on Nyx Assassin to her and her team.
Venomancer
* Heroes that can slow Charge of Darkness by a huge amount: Venomancer, Viper, 
Dazzle, Arc Warden, Lion, Huskar, Shadow Shaman, 
Visage, 
Undying, Jakiro.
Luna
* If Luna chooses to use Eclipse in anticipation right before Spirit Breaker gets to her with Charge of Darkness, she will be able to kill Spirit Breaker before he will be able to kill her as Spirit Breaker's attack speed is rather low.
* Meanwhile, when Spirit Breaker is focusing on any of Luna's allies with Charge of Darkness, Aghanim's Scepter upgraded Eclipse can be used to counter-initate against Spirit Breaker.
* Aghanim's Shard upgraded Moon Glaives allows Luna to reduce damage from Greater Bash and Nether Strike inflicts on her, and damage Spirit Breaker whenever he is close to her, even while he is invisible.
* Lucent Beam can be used to cancel Spirit Breaker's Charge of Darkness under the condition that Luna is able to cast it on time. Lucent Beam can also be used to cancel Nether Strike. But bear in mind, however, that Spirit Breaker can counter this with 
Planar Pocket from Aghanim's Shard which can be used to reflect Lucent Beam back at Luna.
* If Luna buys Linken's Sphere, it will become nearly impossible for Spirit Breaker to reach Luna unless some of Spirit Breaker's allies can pop it and put it on a cooldown.
* Even though Spirit Breaker can evade all of Luna's abilities with Shadow Blade, smart Luna will always buy Dust of Appearance to provide vision on Spirit Breaker to her and her team. Luna can also buy Gleipnir to counter Spirit Breaker's Charge of Darkness and Shadow Blade combo.
Additional:
* If Luna chooses to use Eclipse in anticipation right before Spirit Breaker gets to her with Charge of Darkness, she will be able to kill Spirit Breaker before he will be able to kill her as Spirit Breaker's attack speed is rather low.
* Meanwhile, when Spirit Breaker is focusing on any of Luna's allies with Charge of Darkness, Aghanim's Scepter upgraded Eclipse can be used to counter-initate against Spirit Breaker.
* Aghanim's Shard upgraded Moon Glaives allows Luna to reduce damage from Greater Bash and Nether Strike inflicts on her, and damage Spirit Breaker whenever he is close to her, even while he is invisible.
* Lucent Beam can be used to cancel Spirit Breaker's Charge of Darkness under the condition that Luna is able to cast it on time. Lucent Beam can also be used to cancel Nether Strike. But bear in mind, however, that Spirit Breaker can counter this with Planar Pocket from Aghanim's Shard which can be used to reflect Lucent Beam back at Luna.
* If Luna buys Linken's Sphere, it will become nearly impossible for Spirit Breaker to reach Luna unless some of Spirit Breaker's allies can pop it and put it on a cooldown.
* Even though Spirit Breaker can evade all of Luna's abilities with Shadow Blade, smart Luna will always buy Dust of Appearance to provide vision on Spirit Breaker to her and her team. Luna can also buy Gleipnir to counter Spirit Breaker's Charge of Darkness and Shadow Blade combo.
Venomancer
* Due to lack of magic resistance, Venomancer poisons eats through Windranger's health.
Additional:
* Due to lack of magic resistance, Venomancer abilities eats through Windranger's health.
* Venomancer's multiple slows, to an extent, negates Windrun's mobility.
Luna
* Moon Glaives can ignore certain abilities that either trigger on attack or give evasion under the condition that the heroes who have them are not primary targets. Examples include: 
Centaur Warrunner, 
Windranger, Phantom Assassin, 
Hoodwink etc.
Venomancer
* Heroes who can harass Omniknight out of lane will keep him weak in the mid game: Viper, Venomancer, Clinkz.
Luna
* Guardian Angel does not offer protection from Eclipse, though it will negate damage from Moon Glaives.
* Luna's high magical damage from Lucent Beam and Eclipse can often finish allied heroes before Omniknight can save them with 
Purification.
* Likewise, Luna's high physical damage from Moon Glaives and Lunar Blessing is strong enough to counter debuff immunity from 
Repel.
Additional:
* Guardian Angel does not offer protection from Eclipse, though it will negate damage from Moon Glaives.
* Luna's high magical damage from Lucent Beam and Eclipse can often finish allied heroes before Omniknight can save them with Purification.
Luna
* Heroes that create illusions: Spectre, Shadow Demon, Phantom Lancer, Naga Siren, Chaos Knight, Terrorblade) or bring other units into the fight (such as Nature's Prophet, Lone Druid, Chen, Enchantress, Meepo and Arc Warden) can cause Eclipse to strike the illusions/summons unintentionally. However, in many cases Moon Glaives can resolve this issue and eliminate them before activating Eclipse, but that will require lots of farming for right-click items.
Venomancer
* Untouchable won't mitigate Venomancer's magical damage, and Enchantress is vulnerable to magic damage.
* Both Venomous Gale and Poison Nova lower the amount of healing received by Enchantress and her allies from Nature's Attendants.
Luna
* Enchantress has pitiful HP, even more pitiful than Luna, so Lucent Beam and Eclipse will often harass and/or kill her through her Untouchable.
* With Moon Glaives, Luna can clear Enchantress's creep wave efficiently.
Additional:
* Though Enchantress's 
Untouchable can greatly reduce Luna's attack speed, and can go through any form of Spell Immunity, she has a pitiful HP so Lucent Beam and Eclipse can kill her very quickly.
* Moon Glaives allows Luna to clear Enchantress's creeps very efficiently.
Venomancer
* Due to her slow movement speed,heroes with crowd control and slows can shut down Dawnbreaker:Lion, Crystal Maiden ,Venomancer etc.
Luna
* Luna can easily cancel channeling spells with Lucent Beam and 0.25s Eclipse Lucent Ministun talent for Eclipse, she can also buy Abyssal Blade in case they decide to buy Black King Bar: Enigma's Black Hole, Witch Doctor's Death Ward, Shadow Shaman's Shackles, Lion's Mana Drain, Bane's Fiend's Grip, Pudge's Dismember, Crystal Maiden's Freezing Field, Pugna's Life Drain, Dawnbreaker's Solar Guardian, and Naga Siren's Reel In from Aghanim's Scepter.
Venomancer
* Plague Wards are very hard for Batrider to play against as they provide a lot of vision as well as disable Blink Dagger for a long duration.
Venomancer
* Plague Wards may reveal a hiding Techies. If there's a sentry nearby, they may also reveal a stack of mines hidden in a juking spot.
Venomancer
* Unless Puck is facing the direction he wants to blink while in Phase Shift, the Venomous Gale and 
Noxious Plague combo consistently ticks many times over several seconds, making it very difficult to use Blink Dagger towards the other direction. Puck's slow turning rate makes this even worse.
* Venomancer can use Plague Wards to reveal Puck's position before he even gets a chance to initiate.
Luna
* Heroes that create illusions: Spectre, Shadow Demon, Phantom Lancer, Naga Siren, Chaos Knight, Terrorblade) or bring other units into the fight (such as Nature's Prophet, Lone Druid, Chen, Enchantress, Meepo and Arc Warden) can cause Eclipse to strike the illusions/summons unintentionally. However, in many cases Moon Glaives can resolve this issue and eliminate them before activating Eclipse, but that will require lots of farming for right-click items.
Venomancer
* Venomancer's poison damage over time is very effective against Spectre, who tends to lack magic resistance during the early to mid game.
* Venomancer's multiple slows greatly reduces Spectre's movement speed and mobility.
* Plague Wards can scout out Spectre while she is hiding in trees.
Additional:
* Venomancer's poison damage-over-time are very effective against Spectre, which is lack of magic resistance from early to mid game.
* Venomancer's multiple slows greatly reduces Spectre's low mobility, even through 
Spectral Dagger.
* Plague Wards reveals Spectre while she is hiding on trees.
Luna
* Illusions and summons are double-edge sword type of matchup for Luna. On one hand, they can tank damage from Eclipse, but on the other hand, she can easily clear them before Eclipse with Moon Glaives. Examples include Spectre, Shadow Demon, Phantom Lancer, Naga Siren, Chaos Knight, Terrorblade) or bring other units into the fight (such as Nature's Prophet, Lone Druid, Chen, Enchantress, Meepo and Arc Warden).
Luna
* Lucent Beam allows Luna to easily cancel Freezing Field.
* Without Black King Bar protection, Lucent Beam and Eclipse can make a short work out of Crystal Maiden's abysmal health.
* Skilled Luna will always buy Dust of Appearance, allowing her team to have a vision on Crystal Maiden while invisible and during channeling Freezing Field.
* Even with Black King Bar, Luna can still inflict considerable damage on Crystal Maiden with her attacks, which get empowered with Moon Glaives and Lunar Blessing, also smart and skilled Luna will buy Abyssal Blade to cancel Freezing Field even through Black King Bar in case of emergency. And since Crystal Maiden rarely buys Linken's Sphere, this can be a very big problem for her.
Additional:
* Lucent Beam allows Luna to easily cancel Freezing Field.
* Without Black King Bar protection, Lucent Beam and Eclipse can make a short work out of Crystal Maiden's abysmal health.
* Skilled Luna will always buy Dust of Appearance, allowing her team to have a vision on Crystal Maiden while invisible and during channeling Freezing Field.
* Even with Black King Bar, Luna can still inflict considerable damage on Crystal Maiden with her attacks, which get empowered with Moon Glaives and Lunar Blessing, also smart and skilled Luna will buy Abyssal Blade to cancel Freezing Field even through Black King Bar in case of emergency. Forcing Crystal Maiden to buy Linken's Sphere.
Luna
* Lucent Beam and Eclipse with ministun talent can be used to cancel Requiem of Souls if Shadow Fiend does not have Black King Bar. Likewise, since Shadow Fiend is prone to buying Blink Dagger, an ill-timed Blink Dagger can give Luna a free chance to counter-initiate with Eclipse.
* Moon Glaives and Lunar Blessing allow Luna to outfarm Shadow Fiend in lane and the high physical damage output they provide her can also help her deal with Shadow Fiend even when he buys Black King Bar in late game.
* A well timed Eclipse will burst and kill Shadow Fiend before he even either initiates or gets a chance to retaliate, especially when equipped with Aghanim's Scepter and Ethereal Blade, this could become even worse for Shadow Fiend if he does not have Black King Bar. But bear in mind however, that smart and skilled Shadow Fiend can buy 
Wind Waker to counter this issue.
* Even though Shadow Fiend can evade all of Luna's abilities with Shadow Blade, smart Luna will always buy Dust of Appearance to provide vision on Shadow Fiend to her and her team.
Additional:
* Lucent Beam and Eclipse with ministun talent can be used to cancel Requiem of Souls if Shadow Fiend does not have Black King Bar. Likewise, since Shadow Fiend is prone to buying Blink Dagger, an ill-timed Blink Dagger can give Luna a free chance to counter-initiate with Eclipse.
* Moon Glaives and Lunar Blessing allow Luna to outfarm Shadow Fiend in lane and the high physical damage output they provide her can also help her deal with Shadow Fiend even when he buys Black King Bar in late game.
* A well timed Eclipse will burst and kill Shadow Fiend before he even either initiates or gets a chance to retaliate, especially when equipped with Aghanim's Scepter and Ethereal Blade, this could become even worse for Shadow Fiend if he does not have Black King Bar. But bear in mind however, that smart and skilled Shadow Fiend can buy Wind Waker to counter this issue.
* Even though Shadow Fiend can evade all of Luna's abilities with Shadow Blade, a smart Luna will always buy Dust of Appearance to provide vision on Shadow Fiend to her and her team.
Luna
* Aggressively blinking is not going to end well against Luna, because Queen of Pain will be an easy target for Lucent Beam & Eclipse.
* Queen of Pain's HP is abysmal, so Luna can quickly kill Queen of Pain as soon as she initiates with Blink.
Additional:
* Aggressively blinking is not going to end well against Luna, because Queen of Pain will be an easy target for Lucent Beam & Eclipse.
* Queen of Pain's HP is abysmal, so Luna can quickly kill Queen of Pain as soon as she initiates with Blink.
Luna
* Lucent Beam can be used to cancel both, Tether and Relocate.
* Like with Leshrac's 
Diabolic Edict, 
Lightning Storm and 
Pulse Nova abilities. Luna's Moon Glaives and Eclipse abilities can make short work of Io and its tethered ally, particularly when upgraded with Aghanim's Scepter.
Additional:
* Lucent Beam and 0.25s Eclipse Lucent Ministun talent for Eclipse can be used to cancel both, Tether and Relocate.
* Luna's Moon Glaives and Eclipse abilities can make short work of Io and its tethered ally, particularly when upgraded with Aghanim's Scepter.
Luna
* All assassin-type carries in a one against one situation: Meepo, Phantom Assassin, Riki, Ursa. Luna's only chances are that she buys Ethereal Blade or Black King Bar to gain a slight edge against them, or both items if necessary.
Venomancer
* Heroes that can apply early pressure before Phantom Assassin has farm are massive threats: 
Axe, Viper, Meepo, Jakiro, Pugna, Slark, Venomancer etc.
Luna
* Even though Phantom Assassin can easily kill Luna in few strikes, Luna can also do the same to Phantom Assassin if she is not careful.
* An ill-timed and ill-positioned 
Phantom Strike will make Phantom Assassin an easy target for counter-attack with Eclipse if she does not have Black King Bar available to use and if Phantom Assassin cannot kill Luna fast enough. This can be even better if Luna buys Aghanim's Scepter.
* Moon Glaives can ignore 
Blur's evasion if Luna attacks an enemy near Phantom Assassin.
* Luna can counter Blur's evasion by buying either Silver Edge, or Monkey King Bar, which are common items on Luna.
* Luna just has to be careful about 
Fan of Knives from Aghanim's Shard and 
Coup De Grace, as Fan of Knives can disable Moon Glaives and Lunar Blessing while Coup De Grace can deal serious damage to her even if she is spell immune, though this issue can be solved by buying Ethereal Blade, which is a situational item on Luna.
Additional:
* Even though Phantom Assassin can easily kill Luna in few strikes, Luna can also do the same to Phantom Assassin if she is not careful.
* An ill-timed and ill-positioned Phantom Strike will make Phantom Assassin an easy target for counter-attack with Eclipse if she does not have Black King Bar available to use and if Phantom Assassin cannot kill Luna fast enough. This can be even worse if Luna buys Aghanim's Scepter.
* Moon Glaives can ignore Blur's evasion if Luna attacks an enemy near Phantom Assassin. Aghanim's Shard upgraded Moon Glaives can also reduce damage from Coup De Grace and Moon Glaives Phantom Assassin inflicts on Luna and damage Spirit Phantom Assassin she is close to her. And the Aghanim's Shard upgraded Moon Glaives have true strike for their duration, which renders Blur's evasion insignificant.
* Luna can counter Blur's evasion by buying either Silver Edge, or Monkey King Bar, which are common items on Luna.
* Luna just has to be careful about Fan of Knives from Aghanim's Shard and Coup De Grace, as Fan of Knives can deal health-based damage to Luna and disable Moon Glaives and Lunar Blessing while Coup De Grace can deal serious damage to her even if she is spell immune, though this issue can be partially solved by buying Ethereal Blade, which is a situational item on Luna.
Luna
* Luna's Moon Glaives will not trigger 
Retaliate if they hit some other target first. Also Luna commonly buys items that provide lifesteal such as Satanic, which lets her heal from the damage of Retaliate, meaning that Retaliate has little effect against her.
* Eclipse can be used to counter-initiate against Centaur Warrunner after he jumps in with Blink Dagger, and initiates with 
Hoof Stomp. But remember that Centaur Warrunner can resolve this problem by buying 
Hood of Defiance and it's upgrade 
Pipe of Insight to diminish its damage. Or Blade Mail to reflect the damage of the Eclipse back at Luna.
* Luna also commonly buys Black King Bar, which will allow her to protect herself from both, Centaur Warrunner's abilities (except for the Retaliate), and damage reflect from Blade Mail.
Additional:
* Luna's Moon Glaives will not trigger Retaliate if they hit some other target first. Also Luna commonly buys items that provide lifesteal such as Satanic, which lets her heal from the damage of Retaliate, meaning that Retaliate has limited effect against her.
* Eclipse can be used to counter-initiate against Centaur Warrunner after he jumps in with Blink Dagger, and initiates with Hoof Stomp. But remember that Centaur Warrunner can resolve this problem by buying Hood of Defiance and it's upgrade Pipe of Insight to diminish its damage. Or Blade Mail to reflect the damage of the Eclipse back at Luna.
* Luna also commonly buys Black King Bar, which will allow her to protect herself from both, Centaur Warrunner's abilities (except for the Retaliate), and damage reflect from Blade Mail.
Luna
* Though Bane's 
Enfeeble can weaken Luna's physical damage output, it still does not weaken her magical damage output, although it will still reduce her cast range.
* Without Black King Bar, Luna's Lucent Beam and 0.25 Eclipse Mini-stun talent for Eclipse can be used to disable Bane while he is channeling Fiend's Grip.
* Aghanim's Scepter upgraded Eclipse combined with 0.25 Eclipse Mini-stun can repetively stun Bane, and can even discourage him from even trying to use Fiend's Grip.
Additional:
* Though Bane's Enfeeble can weaken Luna's physical damage output, it still does not weaken her magical damage output (although it can still disable her cast range).
* Without Black King Bar, Luna's Lucent Beam and 0.25 Eclipse Mini-stun talent for Eclipse can be used to disable Bane while he is channeling Fiend's Grip.
* Aghanim's Scepter upgraded Eclipse combined with 0.25 Eclipse Mini-stun can repetively stun Bane, and can even discourage him from even trying to use Fiend's Grip.
* Smart and skilled Luna can buy Abyssal Blade to cancel Fiend's Grip even through Black King Bar in case of emergency. Forcing Bane to buy Linken's Sphere.
Luna
* Without Black King Bar, Luna will be able to cancel Enigma's Black Hole from safe distance with her Lucent Beam or with 0.25s Eclipse Lucent Ministun talent for Eclipse and counter-initiate with Eclipse. This can get even worse for Enigma once Luna gets Aghanim's Scepter and combines it with 0.25s Eclipse Lucent Ministun talent that will allow Luna to use Eclipse from safe distance.
* If Luna chooses to use Eclipse in anticipation right after Enigma jumps in with Blink Dagger, she will be able to kill Enigma before he even gets a chance to use Black Hole. Aghanim's Scepter upgraded Eclipse can be used to counter-initiate against Enigma from safe distance if he has no Black King Bar available to use.
* Luna commonly buys Satanic, which can help her recover from Enigma's Black Hole in case she survives it.
* Moon Glaives combined with Lunar Blessing can make a short work of Enigma's Eidolons before Luna uses Eclipse. Aghanim's Shard upgraded Moon Glaives can be used to reduce damage Luna will take from Enigma's Eidolons and Black Hole if used in anticipation while also clearing waves of Enigma's Eidolons and damaging Enigma if he is too close to Luna.
* Bear in mind, however, that once Enigma gets Black King Bar, Luna will be out of solutions to cancel Black Hole, and going for Abyssal Blade on Luna can be risky due to Abyssal Blade's very short cast range.
Additional:
* Without Black King Bar, Luna will be able to cancel Enigma's Black Hole from safe distance with her Lucent Beam or with 0.25s Eclipse Lucent Ministun talent and counter-initiate with Eclipse. This can get even worse for Enigma once Luna gets Aghanim's Scepter and combines it with 0.25s Eclipse Lucent Ministun talent that will allow Luna to use Eclipse from safe distance.
* If Luna chooses to use Eclipse in anticipation right after Enigma jumps in with Blink Dagger, she will be able to kill Enigma before he even gets a chance to use Black Hole.
* Luna commonly buys Satanic, which can help her recover from Enigma's Black Hole in case she survives it.
* Moon Glaives combined with Lunar Blessing can make a short work of Enigma's Eidolons before Luna uses Eclipse.
* Bear in mind, however, that once Enigma gets Black King Bar, Luna will be out of solutions to cancel Black Hole, and going for Abyssal Blade on Luna can be risky due to Abyssal Blade's very short cast range.
Luna
* Luna's Moon Glaives and Lunar Blessing can help her destroy Tombstone easily, and this becomes more effective if Luna is equipped with Manta Style.
* Spell Immunity of Zombies from Tombstone is a total disadvantage against Luna because Eclipse will strike only Undying, which can turn Undying's own ability against him.
* Though Undying often builds Blade Mail which can turn Luna's burst damage against her, Luna often builds Black King Bar which will allow her to attack Undying freely because Blade Mail cannot pierce spell immunity.
Additional:
* Luna's Moon Glaives and Lunar Blessing can help her destroy Tombstone easily, and this becomes more effective if Luna is equipped with Manta Style.
* Spell Immunity of Zombies from Tombstone is a total disadvantage against Luna because Eclipse will strike only Undying, which can turn Undying's own ability against him.
* Though Undying often builds Blade Mail which can turn Luna's burst damage against her, Luna often builds Black King Bar which will allow her to attack Undying freely because Blade Mail cannot pierce spell immunity.
Luna
* Although Lifestealer can avoid Eclipse with 
Rage and 
Infest, Luna's physical damage can be enough to deal with him.
* Manta Style is a common pick on Luna, which can help her dispel slows from 
Ghoul Frenzy and 
Open Wounds. In addition, Lifestealer is not good against illusions created by Manta Style.
Additional:
* Although Lifestealer can avoid Eclipse with Rage and Infest, Luna's physical damage from Moon Glaives and Lunar Blessing can be enough to deal with him.
* Manta Style is a common pick on Luna, which can help her dispel slows from Ghoul Frenzy and Open Wounds. In addition, Lifestealer is not good against illusions created by Manta Style.
* Even though Aghanim's Scepter upgraded Infest can disarm Luna and allow Lifestealer to attack her from inside even if she is spell immune, Luna can easily counter this with Linken's Sphere, which is a common item on Luna.
Luna
* Cold Embrace is no salvation against Lucent Beam and Eclipse.
* Moon Glaives will not hit a hero affected by Winter's Curse, making it weak against allies, but strong versus enemies.
* Luna has better night vision provided by Lunar Blessing than Winter Wyvern when affected by Arctic Burn.
Additional:
* Cold Embrace is no salvation against Lucent Beam and Eclipse.
* Moon Glaives will not hit a hero affected by Winter's Curse, making it weak against allies, but strong versus enemies.
* Luna has better night vision provided by Lunar Blessing than Winter Wyvern when affected by Arctic Burn.
Venomancer
* Venomancer's slows and magical damage-over-time work well against Axe's complete lack of mobility.
* Plague Ward is especially useful for slowing down Axe, and revealing him before he initiates, as well as putting his Blink Dagger on cooldown.
Additional:
* Venomancer's slows and magical damage-over-time work well against Axe's complete lack of mobility.
* Plague Wards is especially useful for slowing down Axe, and revealing him before he initiates, as well as putting his Blink Dagger on cooldown.
* For the same reasons, Venomancer is a good ally for Axe when the situation is reversed.
Luna
* Even though Luna has a hard time laning against Tinker because of 
Heat-Seeking Missile and 
Laser, she can win against him in late game once she buys Black King Bar, as none of Tinker's spells can bypass spell immunity.
* Lucent Beam and 0.25 Eclipse Lucent Mini-stun talent for Eclipse can be used to cancel 
Rearm and prevent Tinker's escape attempts with 
Boots of Travel. Luna can also use Lucent Beam and Eclipse if she is blinded with Laser.
* An ill-timed and ill-positioned Blink Dagger will make Tinker a very easy target for Luna's Eclipse that can quickly tear him to shreds. This can get even better if Luna buys Aghanim's Scepter and combines it with 0.25 Eclipse Lucent Mini-stun talent for Eclipse.
* However, Luna needs to approach Tinker carefully, as Tinker is a natural 
Scythe of Vyse wielder, and if he gets a jump on Luna first, he will be able to use it to disable and burst down Luna before she can use Black King Bar, Lucent Beam or Eclipse.
Additional:
* Even though Luna has a hard time laning against Tinker because of Heat-Seeking Missile and Laser, she can win against him in late game once she buys Black King Bar, as none of Tinker's spells can bypass spell immunity.
* Lucent Beam and 0.25 Eclipse Lucent Mini-stun talent for Eclipse can be used to cancel Rearm and prevent Tinker's escape attempts with Boots of Travel. Luna can also use Lucent Beam and Eclipse if she is blinded with Laser.
* An ill-timed and ill-positioned Blink Dagger will make Tinker a very easy target for Luna's Eclipse that can quickly tear him to shreds. This can get even better if Luna buys Aghanim's Scepter and combines it with 0.25 Eclipse Lucent Mini-stun talent for Eclipse.
* However, Luna needs to approach Tinker carefully, as Tinker is a natural Scythe of Vyse wielder, and if he gets a jump on Luna first, he will be able to use it to disable and burst down Luna before she can use Black King Bar, Lucent Beam or Eclipse.
Venomancer
* Any hero that can outrange Plague Ward can neutralize them without putting themselves at risk of receiving Poison Sting: Arc Warden, Chen, Clinkz, Drow Ranger, Lina, Mirana, Nature's Prophet, Pugna and Sniper.
* Special mention to heroes that outrange Plague Ward after obtaining talents that increase attack range.
Luna
* Heroes that create illusions: Spectre, Shadow Demon, Phantom Lancer, Naga Siren, Chaos Knight, Terrorblade) or bring other units into the fight (such as Nature's Prophet, Lone Druid, Chen, Enchantress, Meepo and Arc Warden) can cause Eclipse to strike the illusions/summons unintentionally. However, in many cases Moon Glaives can resolve this issue and eliminate them before activating Eclipse, but that will require lots of farming for right-click items.
Venomancer
* Venomancer's damage over time can force Chen to use Hand of God prematurely, potentially wasting a chance to save his allies during a teamfight.
* Venomancer's Poison Nova, Venomous Gale and Plague Ward can easily kill Chen's creeps.
Luna
* Luna's Moon Glaives combined with Lunar Blessing can easily kill Chen's creeps.
* Eclipse can be used after Luna clears all of Chen's creeps to easily kill Chen or any of his allies before he can save them with 
Hand of God. This can get even worse if Luna buys Aghanim's Scepter. And Chen is not a hero that likes to buy Black King Bar to counter this problem.
Additional:
* Luna's Moon Glaives combined with Lunar Blessing can easily kill Chen's creeps.
* Eclipse can be used after Luna clears all of Chen's creeps to easily kill Chen or any of his allies before he can save them with Hand of God. This can get even worse if Luna buys Aghanim's Scepter. And Chen is not a hero that likes to buy Black King Bar to counter this problem.
Luna
* Moon Glaives can ignore certain abilities that either trigger on attack or give evasion under the condition that the heroes who have them are not primary targets. Examples include: Centaur Warrunner, Windranger, Phantom Assassin, Hoodwink etc.
Venomancer
* In general, heroes that can slow down Dragon Knight's movement speed will do well against him. This includes Venomancer and others in addition to the heroes mentioned above.
Luna
* Luna can easily cancel channeling spells with Lucent Beam and 0.25s Eclipse Lucent Ministun talent for Eclipse, she can also buy Abyssal Blade in case they decide to buy Black King Bar: Enigma's Black Hole, Witch Doctor's Death Ward, Shadow Shaman's Shackles, Lion's Mana Drain, Bane's Fiend's Grip, Pudge's Dismember, Crystal Maiden's Freezing Field, Pugna's Life Drain, Dawnbreaker's Solar Guardian, and Naga Siren's Reel In from Aghanim's Scepter.
Luna
* Heroes who are melee but cannot fight back against Eclipse will really struggle with Luna: Monkey King, Alchemist, Timbersaw.
Luna
* Heroes who are melee but cannot fight back against Eclipse will really struggle with Luna: Monkey King, Alchemist, Timbersaw.
Luna
* Even though Moon Glaives can bounce between Meepo and his clones, Meepo can tank Eclipse because of his clones.
* 
Earthbind takes away Luna's mobility advantage.
* Meepo can shutdown Luna's split-push ability with his global presence.
* For the same reasons, Meepo makes a very powerful ally for Luna when they are in the same team.
Venomancer
* Aggressively Poofing and Earthbinding is not going to end well against Venomancer, as he will be an easy target for Noxious Plague.
* Venomancer's constant slows greatly reduce Meepo's mobility.
Luna
* Illusions and summons are double-edge sword type of matchup for Luna. On one hand, they can tank damage from Eclipse, but on the other hand, she can easily clear them before Eclipse with Moon Glaives. Examples include Spectre, Shadow Demon, Phantom Lancer, Naga Siren, Chaos Knight, Terrorblade) or bring other units into the fight (such as Nature's Prophet, Lone Druid, Chen, Enchantress, Meepo and Arc Warden).
Venomancer
* 
Dark Rift allows Underlord to transport allies from poison damage-over-time to the fountain.
* Underlord usually buys Pipe of Insight that gives a magic resistance to allies, inhibiting the damage from Venomancer abilities.
Venomancer
* Heroes with strong area-of-effect damaging and/or disabling abilities will be able to intercept Underlord and his team when they exit from Fiend's Gate: Luna's Aghanim's Scepter upgraded Eclipse, Dawnbreaker's Solar Guardian, Axe's 
Berserker's Call, 
Mars's 
Arena of Blood, Jakiro's Macropyre, Dual Breath and Ice Path, Naga Siren's 
Song of the Siren, 
Razor's 
Eye of the Storm and 
Plasma Field, Lina's 
Light Strike Array, Broodmother's 
Spinner's Snare from Aghanim's Scepter, 
Elder Titan's 
Earth Splitter and 
Echo Stomp, Alchemist's 
Unstable Concoction and 
Acid Spray, 
Queen of Pain's 
Sonic Wave, Dark Seer's 
Wall of Replica and 
Vacuum, Venomancer's Noxious Plague and Poison Nova from Aghanim's Scepter, 
Oracle's Fortune's End and 
Rain of Destiny from Aghanim's Shard, 
Bloodseeker's 
Blood Rite, Enigma's Black Hole and 
Midnight Pulse, Shadow Fiend's 
Requiem of Souls, Batrider's Aghanim's Scepter upgraded 
Flaming Lasso, 
Firefly, 
Flamebreak and 
Sticky Napalm, Ancient Apparition's Ice Blast, Sand King's Epicenter, Sand Storm and Burrowstrike, 
Gyrocopter's 
Call Down, Ember Spirit's 
Sleight of Fist, Death Prophet's 
Exorcism and 
Silence, Monkey King's 
Wukong's Command, Crystal Maiden's Freezing Field, 
Muerta's The Calling, 
Medusa's Stone Gaze, 
Zeus's 
Nimbus from Aghanim's Scepter. 
Dark Willow's 
Bramble Maze, 
Pangolier's 
Swashbuckle, 
Grimstroke's 
Soulbind, 
Ink Swell and 
Stroke of Fate, 
Earthshaker's 
Echo Slam and 
Fissure, 
Puck's 
Dream Coil and 
Waning Rift, 
Winter Wyvern's 
Winter's Curse, 
Magnus's Reverse Polarity.
Luna
* Lunar Blessing gives allies bonus damage and armor required to endure against Atrophy Aura early on.
* Eclipse can be devastating for Underlord's team when they're grouped up for Fiend's Gate, it can also be used to intercept arrivals with Fiend's Gate. And Pit of Malice does not prevent Luna to use it.
* To make things even better, Aghanim's Scepter upgraded Eclipse can finish off Underlord or any of his teammates escape attempts with Fiend's Gate if timed correctly.
Additional:
* Lunar Blessing gives allies bonus damage required to endure against 
Atrophy Aura in most stages of the game.
* Eclipse can be devastating for Underlord's team when they're grouped up for 
Fiend's Gate. It can also be used to intercept arrivals with Fiend's Gate. And 
Pit of Malice does not prevent Luna from using it.
* To make things even worse, Aghanim's Scepter upgraded Eclipse can finish off Underlord or any of his teammates escape attempts with Fiend's Gate if timed correctly.
Venomancer
* 
Slardar can attack through Plague Wards and gain 
Bash of the Deep charges, and 
Templar Assassin can spill 
Psi Blades through Plague Wards too.
Venomancer
* Venomancer's entire arsenal deals lingering damage over a long time and therefore burns through her Refraction very quickly. Not only that, his persistent slow from Poison Sting (it can be re-applied again and again with Plague Ward) allows his team to catch up to her even with the disruption from her Psionic Trap.
Additional:
* Venomous Gale and Plague Wards allow to quickly melt through 
Refraction charges.
* Both Poison Nova and Venomous Gale hit invisible units, so 
Meld cannot be used defensively.
Luna
* Heroes that create illusions: Spectre, Shadow Demon, Phantom Lancer, Naga Siren, Chaos Knight, Terrorblade) or bring other units into the fight (such as Nature's Prophet, Lone Druid, Chen, Enchantress, Meepo and Arc Warden) can cause Eclipse to strike the illusions/summons unintentionally. However, in many cases Moon Glaives can resolve this issue and eliminate them before activating Eclipse, but that will require lots of farming for right-click items.
Luna
* Luna's Moon Glaives and Lunar Blessing can clear waves of Naga Siren's illusions from 
Mirror Image.
* Once Naga Siren's illusions are cleared with Aghanim's Shard upgraded Moon Glaives, Eclipse can often finish off Naga Siren before she can escape with Song of the Siren.
* A well-timed Aghanim's Scepter upgraded Eclipse combined with 0.25 Eclipse Lucent Ministun talent can be casted at long range and allow Luna to burst down Naga Siren faster and repetively stun Naga Siren, preventing her from escaping with Song of the Siren and 
Town Portal Scroll without getting caught in it's range.
* Luna is a natural Black King Bar wielder unlike Naga Siren who barely goes for it, which allows Luna to freely attack Naga Siren during Song of the Siren and potentially get rid of the most of the damage and crowd-control from Naga Siren.
Additional:
* Luna's Moon Glaives and Lunar Blessing can clear waves of Naga Siren's illusions from Mirror Image, especially when combined with Gleipnir and Manta Style. Aghanim's Shard upgraded Moon Glaives can also be used to destroy Naga Siren's illusions and damage the real Naga Siren if they are too close to Luna while also reducing any damage Naga Siren inflicts on Luna for their duration.
* Once Naga Siren's illusions are cleared, Eclipse can often finish off Naga Siren before she can escape with Song of the Siren.
* A well-timed Aghanim's Scepter upgraded Eclipse combined with 0.25 Eclipse Lucent Ministun talent can be casted at long range and allow Luna to burst down Naga Siren faster and repetively stun Naga Siren, preventing her from escaping with Song of the Siren and Town Portal Scroll without getting caught in it's range.
* Luna is a natural Black King Bar wielder unlike Naga Siren who barely goes for it, which allows Luna to freely attack Naga Siren during Song of the Siren and potentially get rid of the most of the damage and crowd-control from Naga Siren.
Luna
* Heroes who cannot fight back during Arena of Blood in the early and mid game: Abaddon, Anti-Mage, Broodmother, Luna, Sniper, 
Troll Warlord, Weaver, Clinkz.
Venomancer
* Venomancer's spells all deal magical damage, ignoring Bulwark.
* Venomancer's multiple slows are especially effective at kiting Mars.
* Plague Ward can attack through Arena Of Blood.
Additional:
* Venomancer's poison attacks are all magical damage, ignoring 
Bulwark.
* Venomancer's multiple slows are especially effective against Mars' low mobility.
* Plague Wards can attack through Arena of Blood.
Luna
* A couple of long-range heroes with excellent laning like Mirana, Lina, Necrophos, Death Prophet. The key to success is sticking together and attacking Luna whenever she enters the range, without even giving Luna a chance to retaliate. Multiple long-range heroes is a reason to pick another hero.
Luna
* Even though Luna has a hard time laning against Necrophos, his 
Ghost Shroud won’t protect him in teamfights because it will increase the damage from Lucent Beam and Eclipse.
* Luna is a natural Black King Bar wielder, and none of Necrophos's spells can bypass spell immunity outside of 
Heartstopper Aura.
Additional:
* Even though Luna has a hard time laning against Necrophos, his Ghost Shroud won’t protect him in teamfights because it will increase the damage from Lucent Beam and Eclipse.
* Luna is a natural Black King Bar wielder, and none of Necrophos's spells can bypass spell immunity outside of Heartstopper Aura.
Venomancer
* Any hero that can outrange Plague Ward can neutralize them without putting themselves at risk of receiving Poison Sting: Arc Warden, Chen, Clinkz, Drow Ranger, Lina, Mirana, Nature's Prophet, Pugna and Sniper.
* Special mention to heroes that outrange Plague Ward after obtaining talents that increase attack range.
Luna
* Luna can deal constant damage to Pugna through the low-cooldown Lucent Beam and her right clicks.
* Life Drain will be always canceled by Lucent Beam if Pugna does not have Black King Bar.
* 
Decrepify can be suicide against Luna due to Lucent Beam and Eclipse.
* 
Nether Ward is rather weak against Luna because unlike other heroes who rely on magical damage to damage or kill enemies, yet their ablities have very high mana costs, Luna does not have abilities that cost a lot of mana and Luna mostly uses her abilities to initiate a teamfight or to finish off fleeing enemy heroes.
* Luna is a common Black King Bar carrier, which allows her to protect herself against Pugna's only-magical damage output.
Additional:
* Luna can deal constant damage to Pugna through the low-cooldown Lucent Beam and her right clicks.
* Life Drain will be always canceled by Lucent Beam if Pugna does not have Black King Bar.
* Decrepify can be suicide against Luna due to Lucent Beam and Eclipse.
* Nether Ward is rather weak against Luna because unlike other heroes who rely on magical damage to damage or kill enemies, yet have very high mana costs, she does not have abilities that cost a lot of mana and Luna mostly uses her abilities to initiate a teamfight or to finish off fleeing enemy heroes.
* Luna is a common Black King Bar carrier, which allows her to protect herself against Pugna's only-magical damage output.
Luna
* All assassin-type carries in a one against one situation: Meepo, Phantom Assassin, Riki, Ursa. Luna's only chances are that she buys Ethereal Blade or Black King Bar to gain a slight edge against them, or both items if necessary.
Luna
* Luna can push very fast with Moon Glaives, which is something Riki cannot deal with well.
* Luna is naturally very fast, making it hard for Riki to trap her in Smoke Cloud.
* Even though Riki can evade Eclipse with his invisibility, smart Luna will always buy Dust of Appearance, providing vision on Riki to her allies and herself.
Additional:
* Luna can push very fast with Moon Glaives, which is something Riki cannot deal with well.
* Luna is naturally very fast, making it hard for Riki to trap her in Smoke Cloud.
* Even though Riki can evade Eclipse with his invisibility, smart Luna will always buy Dust of Appearance, providing vision on Riki to her allies and herself.
Luna
* Heroes that rely on base damage: Luna, Phantom Lancer are easily countered with Anchor Smash.
Luna
* Luna often builds Black King Bar, and none of Tidehunter's spells can bypass spell immunity.
* Though 
Anchor Smash can weaken Luna's physical damage, it does not weaken her magical damage, which means that Lucent Beam and Eclipse deal a lot of magic damage in the early and mid-game, which can bypass Tidehunter's 
Kraken Shell.
Additional:
* Luna often builds Black King Bar, and none of Tidehunter's spells can bypass spell immunity.
* Though Anchor Smash can weaken Luna's physical damage, it does not weaken her magical damage, which means that Lucent Beam and Eclipse deal a lot of magic damage in the early and mid-game, which can bypass Tidehunter's Kraken Shell.
Luna
* A couple of nukers and disablers on the same lane can finish a squishy Luna efficiently despite a teammate's assistance: 
Sven + Shadow Shaman.
Luna
* Luna's high magical damage burst from Lucent Beam and Eclipse can take advantage of Shadow Shaman's low health and strength gain.
* Without Black King Bar, Luna's Lucent Beam and 0.25 Eclipse Mini-stun talent for Eclipse can be used to disable Shadow Shaman while he is channeling Shackles.
* Aghanim's Scepter upgraded Eclipse combined with 0.25 Eclipse Mini-stun can repetively stun Shadow Shaman, and can even discourage him from even trying to use Shackles.
* Luna is a natural Black King Bar wielder, and almost none of Shadow Shaman's spells can bypass spell immunity, except for 
Mass Serpent Ward.
* Bear in mind, however, that if Shadow Shaman gets a jump on Luna first, he will be able to use 
Hex to disable Luna and burst her down before she can use Black King Bar, Lucent Beam or Eclipse. In addition, Moon Glaives cannot bounce on Mass Serpent Wards at all.
Additional:
* Luna's high magical damage burst from Lucent Beam and Eclipse can take advantage of Shadow Shaman's low health and strength gain.
* Without Black King Bar, Luna's Lucent Beam and 0.25 Eclipse Mini-stun talent for Eclipse can be used to disable Shadow Shaman while he is channeling Shackles.
* Aghanim's Scepter upgraded Eclipse combined with 0.25 Eclipse Mini-stun can repetitively stun Shadow Shaman, and can even discourage him from even trying to use Shackles.
* Luna is a natural Black King Bar wielder, and almost none of Shadow Shaman's spells can bypass spell immunity, except for Mass Serpent Ward.
* Bear in mind, however, that if Shadow Shaman gets a jump on Luna first, he will be able to use Hex to disable Luna and burst her down before she can use Black King Bar, Lucent Beam or Eclipse. In addition, Moon Glaives cannot bounce on Mass Serpent Wards at all.
Luna
* Heroes that create illusions: Spectre, Shadow Demon, Phantom Lancer, Naga Siren, Chaos Knight, Terrorblade) or bring other units into the fight (such as Nature's Prophet, Lone Druid, Chen, Enchantress, Meepo and Arc Warden) can cause Eclipse to strike the illusions/summons unintentionally. However, in many cases Moon Glaives can resolve this issue and eliminate them before activating Eclipse, but that will require lots of farming for right-click items.
Luna
* Illusions and summons are double-edge sword type of matchup for Luna. On one hand, they can tank damage from Eclipse, but on the other hand, she can easily clear them before Eclipse with Moon Glaives. Examples include Spectre, Shadow Demon, Phantom Lancer, Naga Siren, Chaos Knight, Terrorblade) or bring other units into the fight (such as Nature's Prophet, Lone Druid, Chen, Enchantress, Meepo and Arc Warden).
Venomancer
* Slardar can attack through Plague Wards and gain Bash of the Deep charges, and Templar Assassin can spill Psi Blades through Plague Wards too.
Luna
* Illusion heroes like the aforementioned Phantom Lancer or Naga Siren, or heroes that tend to buy Manta Style, like Luna or Juggernaut, will give Slardar a hard time, as his damage is single-targeted.
Venomancer
* Venomancer's damage-over-time abilities do little damage against Counterspell.
* Blink helps Anti-Mage get away from Venomancer's slows.
Additional:
* 
Counterspell provides magic resistance, diminishing the effectiveness of Venomancer's spells.
* Venomancer's lack of hard disable allows Anti-Mage to use 
Blink, circumventing the slows Venomancer depends on.
Luna
* Although Anti-Mage can survive Luna's magical damage output with Counterspell, Luna's physical damage from Moon Glaives and Lunar Blessing can be fair enough to deal with him.
* Reckless use of Blink will allow Luna Eclipse can finish off Anti-Mage from early-to-mid stages of the game until Anti-Mage gets Manta Style, Aghanim's Scepter that will give him access to 
Blink Fragment and Aghanim's Shard which will allow Counterspell to weaken enemy spell damage.
* However, Luna needs to finish the match as quickly as possible, because Anti-Mage is a hero who has a big advantage in longer matches once he farms items he needs for teamfights.
Luna
* Frail heroes who lack mobility can also be an easy target to lock down with Chronosphere, such as Drow Ranger, Luna, Sniper, Terrorblade.
Luna
* Luna's Eclipse can be used for counter-attacks and interception against gap-closing heroes who use their blinking abilities without protection or who recklessly jump on her, provided that Luna is able to cast it in time. Examples include: Queen of Pain, Riki, Phantom Assassin, Faceless Void and pretty much any hero who relies on Blink Dagger to close the gap.
Venomancer
* 
Corrosive Skin means Viper can often outlast Venomancer in a battle of attrition.
* Venomancer has no mobility without items, which makes him vulnerable to constant slows.
Luna
* Even though Luna has a hard time laning against Viper due to 
Nethertoxin being able to disable Moon Glaives and Lunar Blessing, Luna can take out Viper once she builds either Black King Bar or Silver Edge which will allow her to attack Viper freely.
* Eclipse can often finish off Viper from early-to-mid stages of the game before he can retaliate as Corrosive Skin gives little magic resistance to him early on.
* Manta Style is an item that Luna commonly buys in most of the games, which lets her disjoint 
Viper Strike. Additionally, illusions from Manta Style can make Viper waste time attacking them.
Additional:
* Even though Luna has a hard time laning against Viper due to Nethertoxin being able to disable Moon Glaives and Lunar Blessing, Luna can take out Viper once she builds either Black King Bar or Silver Edge which will allow her to attack Viper freely.
* Eclipse can often finish off Viper from early-to-mid stages of the game before he can retaliate as Corrosive Skin gives little magic resistance to him early on.
* Manta Style is an item that Luna commonly buys in most of the games, which lets her disjoint Viper Strike. Additionally, illusions from Manta Style can make Viper waste time attacking them.
Luna
* A couple of nukers and disablers on the same lane can finish a squishy Luna efficiently despite a teammate's assistance: Sven + Shadow Shaman.
Venomancer
* Heroes who thrive on teamfights can be a problem, such as Venomancer, Necrophos, Centaur Warrunner...
Venomancer
* While 
Reincarnation is off cooldown, Poison Nova poses less of a threat as Wraith King will return with all debuffs cleared.
* 
Vampiric Spirit can out-heal the slow {tooltip:DoT|Damage over Time} from Poison Sting.
Luna
* Even though Wraith King can easily get a chance to retaliate with Reincarnation after Luna uses Eclipse against him, smart Luna can also turn Reincarnation against him by using Eclipse right after Reincarnation triggers and gets on cooldown, giving Luna an element of surprise she can use against Wraith King.
* Moon Glaives can be used to clear the waves of Wraith King's skeleton warriors summoned from Vampiric Spirit.
Additional:
* Even though Wraith King can easily get a chance to retaliate with Reincarnation after Luna uses Eclipse against him, smart Luna can also turn Reincarnation against him by using Eclipse right after Reincarnation triggers and gets on cooldown, giving Luna an element of surprise she can use against Wraith King.
* Moon Glaives can be used to clear the waves of Wraith King's skeleton warriors summoned from Vampiric Spirit.
Luna
* Heroes that create illusions: Spectre, Shadow Demon, Phantom Lancer, Naga Siren, Chaos Knight, Terrorblade) or bring other units into the fight (such as Nature's Prophet, Lone Druid, Chen, Enchantress, Meepo and Arc Warden) can cause Eclipse to strike the illusions/summons unintentionally. However, in many cases Moon Glaives can resolve this issue and eliminate them before activating Eclipse, but that will require lots of farming for right-click items.
Luna
* Illusions and summons are double-edge sword type of matchup for Luna. On one hand, they can tank damage from Eclipse, but on the other hand, she can easily clear them before Eclipse with Moon Glaives. Examples include Spectre, Shadow Demon, Phantom Lancer, Naga Siren, Chaos Knight, Terrorblade) or bring other units into the fight (such as Nature's Prophet, Lone Druid, Chen, Enchantress, Meepo and Arc Warden).
Venomancer
* Venomancer has low health, which makes him vulnerable to Lina's heavy magic damage.
Plague Wards easily in all stages of the game.
* Fiery Soul attack speed bonus removes
Luna
* Lina has very high magic burst damage to use against the low-health-pool Luna.
Laguna Blade can also be upgraded with Laguna Blade damage is Pure and pierces Spell Immunity to bypass 
Black King Bar, making Lina even more of a threat. Luna however, can easily counter this problem with 
Linken's Sphere, which is a common item for her.
* For the same reasons, Lina makes a very powerful ally for Luna when they are in the same team.