* The damage over time from Viper's Poison Attack and Viper Strike rapidly wear down Refraction charges, allowing Templar Assassin to be damaged. Additionally, Corrosive Skin causes her attacks to apply damage overtime on her as well.
* Nethertoxin is a big threat to Templar Assassin. Her initially low range making it very hard to deal against Nethertoxin in the laning phase. At any stage of the game, a Nethertoxin can always force her to undo her Meld.
Additional:
* All of Viper's abilities quickly burn through Refraction charges.
* Templar Assassin's short range, aside from Psi Blades' spill damage, makes her vulnerable to Poison Attack harassment.
* Templar Assassin traditionally forgoes health and armor items for damage. Outside of Black King Bar, Viper will almost always be able to kill her when Refraction is down.

* All of Jakiro's active skills can be targeted on an area, which is effective at forcing Templar Assassin to move should she Meld away.
* Many of Jakiro's spells utilize damage-over-time mechanics, which makes it easy to strip away layers of Refraction.

* Tiny has low movement speed and attack speed, making him vulnerable to Viper's slows.
* Corrosive Skin provides magic resistance to lower Tiny's magic burst damage.

* Liquid Fire reduces Tiny's already abysmal Attack Speed.
* If Tiny Tosses a hero onto Jakiro, he can react with Ice Path, and potentially Macropyre.
* Tiny's Avalanche is easily countered with Ice Path.
* As Tiny has a very high Health, Liquid Frost is particularly effective against him

* Poison Attack and Viper Strike slows Axe significantly, and puts his Blink Dagger on cooldown, preventing him from initiating.
* Nethertoxin can break Counter Helix.
Additional:
* Nethertoxin prevents Counter Helix from triggering, which significantly lowers Axe's damage output in the early to mid game.
* Viper's various slows and damage over time prevents Axe from initiating as well as putting his Blink Dagger on cooldown.

* Ice Path is a great stun for Berserker's Call and with a Eul's Scepter of Divinity can really catch Axe off guard.
* Dual Breath and Liquid Fire can be a devistating combination for Axe (especially if he takes Battle Hunger at level 1) before he has any natural regeneration sustain from items.
Additional:
* Ice Path neutralizes initiation attempts with Berserker's Call, and its long area of effect discourages follow-ups from Axe's teammates.
* Ice Path serves as a large obstacle to stop Axe from chasing down fleeing stragglers to kill with Culling Blade.
* Jakiro's many damage-per-second skills prevent Axe from initiating with his Blink Dagger. And since Axe rarely buys Black King Bar, he's vulnerable to Jakiro's abilities and counter-initiaions.

* Poison Attack and Viper Strike allowing to kite and slow Earthshaker significally, putting Blink Dagger on cooldown and preventing him from initiating or re-initiating.
* Nethertoxin breaks Aftershock. The silence from Level 25 talent also prevents Earthshaker from initiating or re-initiating.
Additional:
* Being a melee hero, Earthshaker's movement is liable to suppression by Poison Attack and Viper Strike.
* Earthshaker's kit, with the exception of Enchant Totem, deals magic damage. Corrosive Skin effectively blunts his killing potential with a standard Blink combo among other things.
* Nethertoxin disables Aftershock, which removes the stun and bonus damage from Enchant Totem and Echo Slam.

* Both Ice Path and Macropyre are the good setup while Earthshaker after blinking in and stay out of Echo Slam initiation radius.
* Liquid Fire damage over time potentially disable Earthshaker's Blink Dagger.

* Viper's Nethertoxin disables Cloak and Dagger, negating Riki's invisibility and much of his damage. It also makes him more vulnerable to magic damage, which does not go well with Riki's low health pool. With the talent applied, he can't even blink to safety or hide with Tricks of the Trade.
* Corrosive Skin makes it hard for Riki to chase Viper and attack him due to the attack speed slow.
* Viper Strike stays on Riki even after he goes invisible.
* Poison Attack makes it risky for Riki to get last hits and can make the laning phase difficult for him.

* Riki can easily be caught in an Ice Path and Macropyre combo as he finishes Tricks of the Trade, Jakiro just has to be careful about Riki's Smoke Screen when dealing with Riki.

* Nethertoxin prevents the lifesteal from Ransack.
* Meepo and his clones have a lack of magic resistance, so they're vulnerable to Poison Attack & Viper Strike directed onto one clone.

* All of Jakiro's skills are Area of Effect, which can easily affect all Meepos in a targeted area.

* Nethertoxin breaks both Necromastery and Presence of the Dark Lord, reducing his damage massively.
* Corrosive Skin gives Viper bonus Magic Resistance against Shadowraze and Requiem of Souls.
* Viper can easily take advantage of Shadow Fiend's lack of escape and mobility spells with Viper Strike and Poison Attack. Poison Attack also serves as a great way to harass Shadow Fiend.

* Heroes with channeling spells are very easy targets for Jakiro's abilities: Crystal Maiden, Dawnbreaker, Enigma, Pudge, Shadow Fiend, Shadow Shaman, Warlock.

* Heroes who can easily harass Crystal Maiden out of lane in the early game (Clinkz, Viper) can prevent Crystal Maiden from being able to level effectively, and can ultimately slow down her level 6, 12, and 18 to a point where enemy carries already have items to address her ultimate.

* Ice Path allows Jakiro to easily cancel Freezing Field.
* Freezing Field makes Crystal Maiden an easy target for all of his abilities without a Black King Bar.
* With the Aghanim's Scepter upgraded Macropyre, Black King Bar becomes nearly useless for Crystal Maiden, as its high pure damage over time, long duration and ability to pierce spell immunity will either force Crystal Maiden to forcefully cancel Freezing Field or even discourage her from using it at all.
Additional:
* Ice Path allows Jakiro to easily cancel Freezing Field.
* Freezing Field makes Crystal Maiden an easy target for all of Jakiro's abilities without a Black King Bar.
* Aghanim's Scepter upgraded Macropyre can deal pure damage-over-time and pierce spell immunity, making Black King Bar nearly useless for Crystal Maiden, as its high damage over time and long duration can discourage Crystal Maiden to use Freezing Field. Remember, however, that Crystal Maiden can partially solve this issue by buying Aghanim's Schard, which will allow her to simply walk out of Macropyre

* Nethertoxin disables Dawnbreaker's Luminosity|Dawnbreaker. Since she's a melee hero, she needs to close gap to attack and Nethertoxin will be bad for her since she cannot heal.
* Viper Strike and Poison Attack will severely slow her down and combined with Nethertoxin, it will be her death sentence (unless her Celestial Hammer or Solar Guardian are off cooldown). Besides that, chasing her down will be easy due to the slow.

* Heroes with channeling spells are very easy targets for Jakiro's abilities: Crystal Maiden, Dawnbreaker, Enigma, Pudge, Shadow Fiend, Shadow Shaman, Warlock.

* Any hero who can survive Magnus's initiations and manfight him: Huskar, Faceless Void, Weaver, Abaddon, Troll Warlord, Alchemist, Dragon Knight, Night Stalker, Viper.

Additional:
* Most of Magnus' abilities except Empower will trigger damage through Corrosive Skin.
* Poison Attack and Viper Strike can slow Magnus during Skewer, as well as putting his Blink Dagger on cooldown, preventing him from initiating or re-initiating.

* Jakiro's abilities deal damage over time, which can disrupt Magnus's attempts to initiate with Blink Dagger and Reverse Polarity.
* Macropyre not only disables Blink Dagger for a considerable duration, but can also destroy Trees, revealing Magnus's cover and position.

* Hand of God has a long cooldown, so damage over time spells can be hazardous for Chen, forcing him to use it prematurely: Jakiro, Venomancer, Viper, Dazzle, Phoenix.

* Liquid Fire and Dual Breath can clear Chen's creeps, and kill his allies before he uses Hand of God.
* Macropyre can quickly clear Chen's creeps and deal intense damage to his allies.
Additional:
* Jakiro's damage over time force Chen to use Hand of God prematurely, potentially wasting chance to save his allies during teamfight.
* Dual Breath and Macropyre can be used to disrupt Chen's jungling work.

* Nethertoxin disable passives, negating Spectre's damage and survivability by removing both Dispersion and Desolate.
* Due to Haunt and Radiance's burn, Spectre is heavily susceptible to being persistently slowed and damaged by Corrosive Skin without even directly attacking Viper.
* Poison Attack and Viper Strike further slow Spectre's movement speed to a crawl, while his improved magic resistance means he can easily shrug off Radiance's burn.
Additional:
* Nethertoxin disables Desolate and Dispersion, leaving Spectre with far less damage output and damage mitigation in engagements.
* Spectre is one of the weakest heroes at early levels. Viper can stifle her farm with early fights before Spectre purchases any major items.

* Jakiro's early pushing ability from Liquid Fire makes Jakiro very strong against heroes, that take a long time to get online: Morphling, Naga Siren, Spectre.

* Melee heroes with low mobility can be kited and killed by Viper: Treant Protector, Kunkka, Alchemist, Troll Warlord, Wraith King, Tiny, Sven.

* With Dual Breath, Liquid Fire and Macropyre Jakiro can quickly remove all Living Armor from a target.
* Ice Path allows Jakiro to prevent Treant Protector from using Overgrowth while staying at a safe distance.

* Nethertoxin cuts off Gravekeeper's Cloak, Visage's primary defense mechanism.
* Viper can ignore Grave Chill's attack speed slow with his magic damage output.
Additional:
* Since Visage is a slow hero, Viper can easily kite him with Poison Attack and Viper Strike while successfully chipping away at Gravekeeper's Cloak.
* Nethertoxin removes all layers of Gravekeeper's Cloak, leaving Visage exposed.
* Corrosive Skin makes Viper highly resistant to Soul Assumption.

* Jakiro's area-of-effect abilities make him strong against heroes who rely on illusions and summons: Terrorblade, Naga Siren Chaos Knight, Phantom Lancer, Broodmother, Nature's Prophet, Lycan, Wraith King, Visage.

* Melee heroes with low mobility can be kited and killed by Viper: Treant Protector, Kunkka, Alchemist, Troll Warlord, Wraith King, Tiny, Sven.

* Jakiro's reliance on his abilities can cause struggles for heroes who rely on evasion or blinds to get upper hand: Phantom Assassin, Windranger, Riki, Troll Warlord, Keeper of the Light.

* Heroes with Break abilities will prevent Slark from regenerating and gaining Essence Shift stacks: Viper, Shadow Demon, etc.

Additional:
* Nethertoxin negates Essence Shift and the regeneration aspect of Shadow Dance.
* Dark Pact doesn't mean a lot against Viper's ubiquitous slows.
* Viper becomes a relevant presence in team fights before Slark can procure his standard items (e.g. Shadow Blade).

* Heroes with AoE abilities will hit Slark in Shadow Dance: Lina, Jakiro, Underlord, Leshrac, Dark Seer, Earthshaker, Timbersaw, Crystal Maiden.

* Heroes who can harass Omniknight out of lane will keep him weak in the mid game: Viper, Venomancer, Clinkz.

* Heroes with large magical AoE damage will fare well against Omniknight: Lich, Ancient Apparition, Jakiro, Disruptor.

* Nethertoxin disables Bristleback's passive.
* Viper Strike and Poison Attack slow down Bristleback's movement speed so he's unable to get out from Nethertoxin.
Additional:
* Nethertoxin disables Bristleback and prevents Warpath from building stacks. Besides losing his defensive passive, Bristleback also loses his ability to build up damage over lengthy battles.
* Viper can perpetually kite Bristleback with Poison Attack and Viper Strike.

* While Jakiro's damage is going to be little more then average against him due to his Bristleback. His large quantity of stuns can prevent Bristleback from getting his much needed Warpath stacks, while also giving his allies a chance to counter his high defense.
* Dual Breath and Liquid Frost both reduce Movement Speed, removing one of Bristlebacks greatest strengths
* Liquid Fire reduces Bristlebacks Attack Speed, making it harder for him to burst down a hero with Warpath
* However Bristleback can generally catch and kill a lone Jakiro. Your only effective in a group

* In the early game, a Dragon Knight without Black King Bar is basically defenseless against Viper.
* Viper can harass Dragon Knight at any time with his Poison Attack.
* Corrosive Skin reduces damage from Dragon Fire and inflicts damage to him.
* Nethertoxin disables Dragon Blood, negating his main survivability.
* Viper Strike and Poison Attack can severely slow him down even with his Elder Dragon Form.
Additional:
* Dragon Knight is easily harassed by Poison Attack after the laning stage ends.
* Corrosive Skin protects Viper from Breathe Fire and returns damage.
* Nethertoxin mitigates Dragon Blood, Dragon's Knight main source of armor and health regeneration.
* Between Poison Attack and Viper Strike, Viper can keep Dragon Knight permanently slowed even in Elder Dragon Form.

* Nethertoxin breaks the damage block from Bulwark.
* Poison Attack and Viper Strike's slows make it difficult for Mars to contribute to fights due to his low mobility.
Additional:
* Nethertoxin disables Bulwark entirely, making Mars far less tanky. Using Nethertoxin inside Arena of Blood may discourage enemies from following up with Mars' initiation.
* Rod of Atos is currently common on Viper and keeps Mars in position long enough to be killed.
* Beware that Viper is not very tanky earlier in the game, so positioning against Mars is important since a well-timed Spear of Mars can be the end of Viper.

* Nethertoxin prevents Timbersaw from gaining stacks on Reactive Armor.

* The slow applied from Corrosive Skin offsets the movement speed bonus granted by Scorched Earth and the tick-based damage from Infernal Blade and Doom will continually slow Doom down. This allows Viper, much like Sniper, to 'kite' Doom and keep him at a safe distance between the two. Additionally, Corrosive Skin applies an attack-speed slow which is fairly crippling to a hero such as Doom that, naturally, has a high base attack-time, poor agility gain and builds little attack-speed items.
* Since Doom does not disable auto-cast abilities, Viper's Poison Attack will continue to work. Doom may find it hard to close the distance between himself and Viper, and thusly difficult to effectively lockdown and continually deal damage through his abilities.

* Nethertoxin prevents the buildup of Jingu Mastery stacks.
* Viper's poison magical damage-over-time stops Monkey King from using Tree Dance. It also ignores the extra armor bestowed by Wukong's Command.
Additional:
* Nethertoxin prevents the buildup of Jingu Mastery stacks.
* Monkey King's high base movement speed is of little worth against the array of slows Viper possesses.
* All of Viper's magical damage over time stops Monkey King from using Tree Dance. It also ignores the extra armor bestowed by Wukong's Command.

* Batrider has poor survivablilty, relying on his mobility from Firefly to survive. Stunning him with Ice Path of Liquid Frost can easily spell his doom
* Batrider prefers to cast Flaming Lasso on the squishest or the tankiest hero. Which Jakiro is not squishy, nor his generally the tank of the team, Due to this you can usually save allies with Ice Path and Liquid Frost, while also potentially removing an entire hero from play for a short period of time
* Even if he does cast Flaming Lasso on Jakiro, he will generally drag you into a great setup for Ice Path and Macropyre

* Poison Attack makes it hard for Void Spirit to lane against him.
* Corrosive Skin reduces the magical damage from Void Spirit's spells.

* Nethertoxin breaks Multicast.
* Corrosive Skin minimizes the damage from Ignite and Fireblast.

* Corrosive Skin minimizes the damage Viper takes from all of Disruptor's skills.

* Jakiro has 3 damage over time spells, 2 of which are from debuffs on Puck (Dual Breath and Liquid Fire) and 1 affecting an entire area (Macropyre), making it easy for him to disable the blink dagger.
* Ice Path is also strong against Puck, as he can cast it towards Puck during Phase Shift, who then gets instantly stunned once Phase Shift ends.
Additional:
* Jakiro has 3 damage over time spells, 2 of which are from debuffs on Puck (Dual Breath and Liquid Fire) and 1 affecting an entire area (Macropyre), making it easy for him to disable the blink dagger.
* Ice Path is also strong against Puck, as he can cast it towards Puck during Phase Shift, who then gets instantly stunned once Phase Shift ends.

* Corrosive Skin will protect Viper from Techies' magical damage.
* Even though Reactive Tazer will disarm Viper if he attacks Techies with Poison Attack, he does lots of damage with his other abilities that can still kill Techies.

* Corrosive Skin severely reduces Zeus's damage output throughout the game.
* During the laning stage, Viper can abuse Zeus' reliance on spells by hugging the creep wave. Zeus will take constant damage over time from Corrosive Skin unless he drives Viper from the lane or returns to farming in his absence.
* Prior to buying Blink Dagger or Force Staff, Zeus is fragile and possesses low mobility. Any of Viper's numerous slows can set up an easy kill.
Additional:
* Corrosive Skin counters Zeus in lane by canceling the effects of Clarity as Zeus relies on Arc Lightning to farm and secure last hits.
* Corrosive Skin also increases Viper's magic resistance to shrug off Zeus's magical nukes.
* Nethertoxin breaks Static Field.
* Due to Zeus' poor mobility, Viper Strike will cripple Zeus and will allow Viper and his teammates to land a lot of attacks.

* Nethertoxin disables Vengeance Aura.
* Vengeful Spirit has no mobility spells aside from Nether Swap, which Viper can take advantage of with his slows.
* Viper can easily bully Vengeful Spirit out of a lane with Poison Attack.
Additional:
* Nethertoxin prevents the attack damage bonus from Vengeance Aura and the components of Nether Swap.
* Both Magic Missile and Wave of Terror are counteracted by Corrosive Skin, making Vengeful Spirit's fighting harder against Viper.

* Corrosive Skin minimizes the damage from Impale and Mana Burn.
* Nyx Assassin cannot survive several poison damage-over-time, even Spiked Carapace is activated.

* Corrosive Skin minimizes the damage Viper takes from all of Ancient Apparition's abilities.
* Ancient Apparition's slow movement speed, squishy nature, and lack of escape abilities can easily be taken advantage of through Poison Attack and Viper Strike.

* Nethertoxin prevents buildup of Fiery Soul stacks.
* Corrosive Skin provides magic resistance against Lina's spells.
* Poison Attack and Viper Strike can burn away Lina's small health pool.

* Viper does large amounts of magic damage over time, meaning that if a Necrophos uses Ghost Shroud, Viper's abilities will greatly reduce Necrophos survivability, and may actually kill him.
* By the same token, Viper can use his Viper Strike on Necrophos if he attempts to heal himself with Ghost Shroud, and depending on any other effects Necrophos may have from him, (IE:Poison Attack,Corrosive Skin), Viper can often kill Necrophos while he is in his Ghost Shroud.
* Viper's Corrosive Skin helps him take reduced damage from all of Nercophos spells that deal magical damage, which is Necrophos's only source of damage.
Additional:
* Nethertoxin prevents Heartstopper Aura from dealing damage or healing Necrophos.
* Viper's magic damage is amplified whenever Ghost Shroud is used.
* Corrosive Skin makes Viper tankier against Death Pulse and Reaper's Scythe.

* Corrosive Skin gives Viper additional resistance to Phoenix's magical damage, and since they deal damage over time, Phoenix would be constantly afflicted by his passive's own debuff, making him not an ideal target for Phoenix's harassment. Phoenix's abilities also constantly drain its own health away, becoming more vulnerable to Poison Attack.

* Corrosive Skin means Viper can often outlast Venomancer in a battle of attrition.
* Venomancer has no mobility without items, which makes him vulnerable to constant slows.

* Because Poison Attack has no cooldown, Aphotic Shield is ineffective as a hard dispel.
* Nethertoxin prevents Borrowed Time from activating passively and blocks Curse of Avernus

* Jakiro's area of effect abilities can hit Dark Willow even while she is hidden during the Shadow Realm.
* Waiting about 2 seconds after Willow casts Shadow Realm to cast Ice Path will stun her while her Shadow Realm is at it's maximum damage.
* Jakiro can stun Willow when there is about 1 second left on Cursed Crown, Jakiro's Ice Path stun lasts slightly longer then Cursed Crown,

* Viper's poison abilities can slow Bounty Hunter's movement speed and allows to chase him with True Sight items.
* Nethertoxin can break Jinada, and the silence from level 25 prevents Bounty Hunter from using all of his spells.

* Jakiro's area-of-effect ability arsenal allows him to affect multiple heroes at once, giving Io difficulties in saving them as he can only heal one hero at a time with Tether.
* Ice Path can be used to cancel both, Tether and Relocate.
* Jakiro commonly buys Rod of Atos that can be used to cancel Relocate, prevent Io in escaping with Tether and make Io easy target for Ice Path and Macropyre.
Additional:
* Jakiro's area-of-effect ability arsenal allows him to affect multiple heroes at once, giving Io difficulties in saving them as he can only heal one hero at a time with Tether.
* Ice Path can be used to cancel both, Tether and Relocate.
* Jakiro commonly buys Rod of Atos that can be used to cancel Relocate, prevent Io in escaping with Tether and make Io easy target for Ice Path and Macropyre.

* Viper's Poison Attack and Viper Strike that can slow Razor, and is one of the few heroes that can keep him immobile.
* Altogether, Viper's skills reduce Razor's attack speed, heavily reducing the benefit of the damage drain from Static Link.
Additional:
* Storm Surge is counteracted by Nethertoxin, leaving Razor without faster MS.
* Static Link's damage drain doesn't bother Viper a lot as most of his early to mid game damage is magical.

* Nethertoxin breaks Fury Swipes, making Viper a decent counter to Ursa in a laning stage.
* Viper Strike is a strong, undispellable slow, making it much easier to kite Ursa for everyone.

* His Poison Attack is very useful against Huskar, since he tends to stay at low health.
* Nethertoxin disables passive skills like Berserker's Blood.
* It is dangerous for Huskar to jump on Viper because Corrosive Skin and Viper Strike with the slowdown of movement and attack speed which usually will be deadly for Huskar.
Additional:
* Nethertoxin disables Berserker's Blood, which Huskar relies upon for attack speed and healing.
* The damage from Burning Spear and Life Break is largely absorbed by Corrosive Skin. It also will return some damage, making it risky to use Burning Spears in the laning stage.
* Because Huskar wants to be on low health for Berserker's Blood, he is particularly vulnerable to Poison Attack.

* Heroes that commonly attack etheral units do not have any problems against Muerta such as Tinker, Jakiro, Pugna or Ogre Magi

* Heroes with break can disable Untouchable for a while: Doom and Shadow Demon (via Aghanim's Scepter), Viper, Shadow Shaman with Hex Breaks talent.

* Melee heroes with low mobility can be kited and killed by Viper: Treant Protector, Kunkka, Alchemist, Troll Warlord, Wraith King, Tiny, Sven.

* Viper can bully Alchemist out of mid lane quite easily, forcing him to either retreat into jungle, or stay harassed in lane, and get very few last hits. Vipers break also completely disables Greevil's greed which prevents Alchemist to earn his amazing amounts of money.

* Heroes with Attack speed decreasing skills: Jakiro, Viper Lich

* With his AoE damage, Jakiro can easily kill Chaos Knight's Phantasm illusions.
* Chaos Knight usually doesn't buy a Black King Bar, making him vulnerable to an Ice Path into Macropyre combination.
Additional:
* With his AoE damage, Jakiro can easily kill Chaos Knight's Phantasm illusions.
* Chaos Knight usually doesn't buy a Black King Bar, making him vulnerable to an Ice Path into Macropyre combination.

* Melee heroes with low mobility can be kited and killed by Viper: Treant Protector, Kunkka, Alchemist, Troll Warlord, Wraith King, Tiny, Sven.

* Heroes that can slow Charge of Darkness by a huge amount: Venomancer, Viper, Dazzle, Arc WardenLion

* Heroes with channeling spells are very easy targets for Jakiro's abilities: Crystal Maiden, Dawnbreaker, Enigma, Pudge, Shadow Fiend, Shadow Shaman, Warlock.

* Nethertoxin breaks Sniper's passives.
* Viper Strike together with Poison Attack can slow Sniper and tears through his low health and mobility.

* Mana Drain can be easily canceled with Ice Path. However, Lion can counter this by buying his Aghanim's Shard though, that is no longer possible, But Jakiro's Marcopyre will deal damage through his Spell Immunity, forcing him to cancel it or die
* Lion has very strong single target capabilities, but suffers against multiple heroes, while Jakiro almost always with someone else, His abilities also have a much shorter cast range then Jakiro's, allowing him to cast your spells before he can get off his Hex or Earth Spike
* Jakiro can also save an ally who Lion is attempting to Finger of Death by casting Ice Path on Lion.

* Jakiro's skill arsenal can ruin Nature's Prophet's gameplay: Dual Breath and Liquid Fire can clear treants from Nature's Call while simultaneously slowing Nature's Prophet, Ice Path can disrupt Nature's Prophet's escaping attempt with Teleportation, and Macropyre can easily clear treants from Nature's Call.
Additional:
* Jakiro's Macropyre can help him to escape from Sprout and quickly clears Treants.
* Jakiro can disrupt Nature's Prophet's escape attempt with Sprout and Teleportation by using Ice Path.

* Most of the of Jakiro's damage-over-time abilities put Blink Dagger on cooldown, potentially forcing Enigma to prematurely activate Black King Bar.
* Jakiro's Dual Breath, Liquid Fire, Macropyre and Liquid Frost from Aghanim's Shard can take out Enigma's Eidolons, reduce Enigma's attack speed and put Enigma's Blink Dagger on cooldown.
* Jakiro can easily cancel Black Hole with Ice Path as Enigma is a very easy target while channeling it.
* Aghanim's Scepter upgraded Macropyre can deal pure damage-over-time and pierce spell immunity, which can discourage Enigma from initiating with Black Hole.
Additional:
* Most of the of Jakiro's damage-over-time abilities put Enigma's Blink Dagger on cooldown, potentially forcing him to prematurely activate Black King Bar.
* Jakiro's Dual Breath, Liquid Fire, Macropyre and Liquid Frost from Aghanim's Shard can take out Enigma's Eidolons, reduce Enigma's attack speed and put Enigma's Blink Dagger on cooldown.
* Jakiro can easily cancel Black Hole with Ice Path as Enigma is a very easy target while channeling it.
* Aghanim's Scepter upgraded Macropyre can deal pure damage-over-time and pierce spell immunity, which can discourage Enigma from initiating with Black Hole.

* Melee heroes with low mobility can be kited and killed by Viper: Treant Protector, Kunkka, Alchemist, Troll Warlord, Wraith King, Tiny, Sven.

* Jakiro's area-of-effect abilities make him strong against heroes who rely on illusions and summons: Terrorblade, Naga Siren Chaos Knight, Phantom Lancer, Broodmother, Nature's Prophet, Lycan, Wraith King, Visage.

* Jakiro's wide area-of-effect abilities allow him to clear the waves of Terrorblade's illusions and to damage real Terroblade.
* Both, Liquid Fire and Liquid Frost from Aghanim's Shard deal magical damage, which can bypass Terrorblade's high armor.
* Jakiro often buys Hurricane Pike, which combined with +275 Attack Range talent allows Jakiro to harass Terrorblade from safe distance without getting in range of Sunder and outrange Terrorblade greatly, even during Metamorphosis.
* Aghanim's Scepter upgraded Macropyre can deal huge pure damage to Terrorblade and his illusions and can hurt real Terrorblade even if he is protected by Black King Bar thanks to it's ability to pierce spell immunity when upgraded.
* Just bear in mind, however, that Jakiro's abilites are all dealing damage-over-time, so a well-timed Sunder may spell a doom for Jakiro if Terrorblade can get close to him unless Jakiro builds Black King Bar or Linken's Sphere and other items that can give him a burst damage.
Additional:
* Jakiro's wide area-of-effect abilities allow him to clear the waves of Terrorblade's illusions and to damage real Terroblade.
* Both, Liquid Fire and Liquid Frost from Aghanim's Shard deal magical damage, which can bypass Terrorblade's high armor.
* Jakiro often buys Hurricane Pike, which combined with +275 Attack Range talent allows Jakiro to harass Terrorblade from safe distance without getting in range of Sunder and outrange Terrorblade greatly, even during Metamorphosis.
* Aghanim's Scepter upgraded Macropyre can deal huge pure damage to Terrorblade and his illusions and can hurt real Terrorblade even if he is protected by Black King Bar thanks to it's ability to pierce spell immunity when upgraded.
* Just bear in mind, however, that Jakiro's abilites are all dealing damage-over-time, so a well-timed Sunder may spell a doom for Jakiro if Terrorblade can get close to him unless Jakiro builds Black King Bar or Linken's Sphere and other items that can give him a burst damage.

* Heroes that can apply early pressure before Phantom Assassin has farm are massive threats: Axe, Viper, Meepo, Pugna, Slark etc.

* Jakiro's reliance on his abilities can cause struggles for heroes who rely on evasion or blinds to get upper hand: Phantom Assassin, Windranger, Riki, Troll Warlord, Keeper of the Light.

* Both Jakiro's Ice Path and Liquid Frost can be used to cancel Life Drain from either yourself or an ally.
* Decrepify only makes Pugna even more vulnerable to Jakiro's magical damage, And it has no adverse effects on Jakiro himself.
* Aghanim's Scepter upgraded Macropyre can deal pure damage-over-time and pierce spell immunity, which can discourage Pugna from initiating with Life Drain.
* Just be warned that Nether Ward can do some considerable damage to Jakiro due to high mana costs on his abilities.

* Death Ward can be easily canceled by Jakiro, or even turned against him with Macropyre, due to it's attack range being smaller then Jakiro's cast range
* Voodoo Switcheroo is even easier to land Jakiro's Macropyro/Ice Path combo
* Unlike Crystal Maiden, his Scepter does not allow him to move while using it
* While Maledict can be quite effective on Jakiro, but with his arsenal of stuns, it is very difficult to get a strong Maledict on him
* However his Maledict/Death Ward combo will still quickly eliminate Jakiro
* On the other hand. Voodoo Restoration will partly protect his allies from your spells, as it heals based on their Max Health once he gets his Talent (Level 25),
* Before then though, it won't make a dent in the damage you deal

* Corrosive Skin makes Viper receive less damage from Invoker's spells
* Viper can harass Invoker with his Poison Attack in the early game.
* Viper Strike and Poison Attack can kill Invoker easily if Ghost Walk is on cooldown.

* Jakiro relies entirely on dealing damage through his area-of-effect abilities, making Enfeeble less effective against him, although it will still reduce his cast range.
* An ill-timed Nightmare can give Jakiro a good setup for all of his ablities.
* Jakiro can easily cancel Fiend's Grip with Ice Path, as Bane is very easy target while channeling it.
* Aghanim's Scepter upgraded Macropyre can deal pure damage-over-time and pierce spell immunity, which can discourage Bane from even trying to use Fiend's Grip.
Additional:
* Jakiro relies entirely on dealing damage through his area-of-effect abilities, making Enfeeble less effective against him, although it will still reduce his cast range.
* An ill-timed Nightmare can give Jakiro a good setup for all of his ablities.
* Jakiro can easily cancel Fiend's Grip with Ice Path, as Bane is very easy target while channeling it.
* Aghanim's Scepter upgraded Macropyre can deal pure damage-over-time and pierce spell immunity, which can discourage Bane from even trying to use Fiend's Grip.

* Nethertoxin cancels out Kraken Shell and stops the hard dispel from passively activating, preventing Tidehunter from functioning as a frontline tank.
* Anchor Smash is mostly irrelevant against a ranged hero.
* Tidehunter relies on the threat of Ravage, which has an obscenely long cooldown. Viper can exploit the downtime with his short cooldowns.

* Jakiro's reliance on his abilities can cause struggles for heroes who rely on evasion or blinds to get upper hand: Phantom Assassin, Windranger, Riki, Troll Warlord, Keeper of the Light.

* Heroes with channeling spells are very easy targets for Jakiro's abilities: Crystal Maiden, Dawnbreaker, Enigma, Pudge, Shadow Fiend, Shadow Shaman, Warlock.

* Jakiro's spells inflict AoE damage, meaning he can take down Phantom Lancer's illusion army very quickly.
* Bear in mind, however, that once Phantom Lancer buys Diffusal Blade which can burn Jakiro's mana, Jakiro will be vulnerable to Phantom Lancer 's counter-attacks if her runs out of mana.
Additional:
* Jakiro's AoE abilities are great against Phantom Lancer:
* Dual Breath slows down and damages Phantom Lancer and his illusions.
* Liquid Fire will not only deal AoE damage but also lowers Phantom Lancer's attack speed.
* Ice Path and Macropyre combo can easily clear all of Phantom Lancer's illusions.
* Jakiro can predict Doppelganger and Ice Path on top.

* Heroes with channeling spells are very easy targets for Jakiro's abilities: Crystal Maiden, Dawnbreaker, Enigma, Pudge, Shadow Fiend, Shadow Shaman, Warlock.

* Jakiro's damage over time abilities can clear Naga Siren's illusions and can hurt real Naga Siren even for the duration of Song of the Siren.
* Naga Siren is not a hero that likes to go for Black King Bar, and that makes her very vulnerable to Jakiro's damage over time in every phase of the game.
Additional:
* Jakiro's damage over time abilities can clear Naga Siren's illusions and can hurt real Naga Siren even for the duration of Song of the Siren.
* Naga Siren is not a hero that likes to go for Black King Bar, and that makes her very vulnerable to Jakiro's damage over time in every phase of the game.

* Broodmother and her Spiderlings need to be very careful during the laning stage against Jakiro, as Jakiro can take down Broodmother's Spiderlings, preventing her from pushing as well as gaining a good amount of gold.

* Jakiro's area-of-effect abilities make him strong against heroes who rely on illusions and summons: Terrorblade, Naga Siren Chaos Knight, Phantom Lancer, Broodmother, Nature's Prophet, Lycan, Wraith King, Visage.