* Since Windranger is bad against magical damage, heroes with continuous magical damage or magical nukes can blast her: Zeus, Tinker, Leshrac, Viper, Skywrath Mage, Lion, Lina, Venomancer.

* Lifestealer's Rage and Open wounds become useless when Meepo has 4 or more clones, as Ransack will heal Meepo too quickly for Lifestealer to take down.

* Even though Moon Glaives can bounce between Meepo and his clones, Meepo can tank Eclipse because of his clones.
* Earthbind takes away Luna's mobility advantage.
* Meepo can shutdown Luna's split-push ability with his global presence.
* For the same reasons, Meepo makes a very powerful ally for Luna when they are in the same team.

* Corrosive Skin makes Viper receive less damage from Invoker's spells
* Viper can harass Invoker with his Poison Attack in the early game.
* Viper Strike and Poison Attack can kill Invoker easily if Ghost Walk is on cooldown.

* Tinker who can't fight multiple heroes will suffer greatly against Ransack and Earthbind.

* Heroes with high mobility can be prevented from using it to their advantage with Earthbind, even if they pack a dangerous arsenal: Earth Spirit, Ember Spirit, Storm Spirit, Nature's Prophet, Phantom Assassin, Riki, Anti-Mage, Weaver.
* See items and abilities disabled by roots

* Melee heroes with low mobility can be kited and killed by Viper: Treant Protector, Kunkka, Alchemist, Troll Warlord, Wraith King, Tiny, Sven.

* Melee heroes with low mobility can be kited and killed by Viper: Treant Protector, Kunkka, Alchemist, Troll Warlord, Wraith King, Tiny, Sven.

* Heroes with high mobility can be prevented from using it to their advantage with Earthbind, even if they pack a dangerous arsenal: Earth Spirit, Ember Spirit, Storm Spirit, Nature's Prophet, Phantom Assassin, Riki, Anti-Mage, Weaver.
* See items and abilities disabled by roots

* Pugna's Nether Ward doesn't really hurt Meepo since he usually buys attribute items to tank up and can be killed very quickly by 4 clones. Decrepify can amplify Poof's damage should Pugna use it to avoid Meepo's right clicking.

* Heroes that can jump and kill him: Meepo, Clinkz, Templar Assassin

* Heroes with Attack speed decreasing skills: Jakiro, Viper Lich

* Any hero who can survive Magnus's initiations and manfight him: Huskar, Faceless Void, Weaver, Abaddon, Troll Warlord, Alchemist, Dragon Knight, Night Stalker, Viper.

Additional:
* Most of Magnus's abilities except Empower will trigger damage through Corrosive Skin.
* Poison Attack and Viper Strike can slow Magnus during Skewer, as well as putting his Blink Dagger on cooldown, preventing him from initiating or re-initiating.

* Naga Siren's Song of the Siren may be useful but Poof will destroy all of her illusions.

* Heroes with powerful rooting abilities will disable most of Pangolier's skills, a bonus point if it pierces spell immunity since it will also be able to stop Pangolier during his Rolling Thunder: Treant Protector, Meepo, Crystal Maiden, Dark Willow, Underlord, Naga Siren

* Corrosive Skin severely reduces Zeus's damage output throughout the game.
* During the laning stage, Viper can abuse Zeus' reliance on spells by hugging the creep wave. Zeus will take constant damage over time from Corrosive Skin unless he drives Viper from the lane or returns to farming in his absence.
* Prior to buying Blink Dagger or Force Staff, Zeus is fragile and possesses low mobility. Any of Viper's numerous slows can set up an easy kill.
Additional:
* Corrosive Skin counters Zeus in lane by canceling the effects of Clarity as Zeus relies on Arc Lightning to farm and secure last hits.
* Corrosive Skin also increases Viper's magic resistance to shrug off Zeus's magical nukes.
* Nethertoxin breaks Static Field.
* Due to Zeus' poor mobility, Viper Strike will cripple Zeus and will allow Viper and his teammates to land a lot of attacks.

* Thundergod's Wrath strikes only the first Meepo.
* Zeus has low mobilty so consecutive Earthbinds are easy to hit and he'll quickly die from Poofs.

* Viper does large amounts of magic damage over time, meaning that if a Necrophos uses Ghost Shroud, Viper's abilities will greatly reduce Necrophos survivability, and may actually kill him.
* By the same token, Viper can use his Viper Strike on Necrophos if he attempts to heal himself with Ghost Shroud, and depending on any other effects Necrophos may have from him, (IE:Poison Attack,Corrosive Skin), Viper can often kill Necrophos while he is in his Ghost Shroud.
* Viper's Corrosive Skin helps him take reduced damage from all of Necrophos spells that deal magical damage, which is his only source of damage.
Additional:
* Viper Strike prevents Heartstopper Aura from dealing damage or healing Necrophos.
* Viper's magic damage is amplified whenever Ghost Shroud is used.
* Corrosive Skin makes Viper tankier against Death Pulse and Reaper's Scythe.

* Necrophos struggles at clearing away durable illusions or summons. Meepo can overwhelm Necrophos with his many duplicates, especially in the later stages of the game, and his Earthbind will prevent Necrophos from getting away, even if he casts Ghost Shroud.
* Meepo's high burst damage from Poof can make it difficult for to Necrophos to stay alive, and as Necrophos excels in extended fights, he will not be able to do as much damage as he intends to.

* Corrosive Skin gives Viper additional resistance to Phoenix's magical damage, and since they deal damage over time, Phoenix would be constantly afflicted by his passive's own debuff, making him not an ideal target for Phoenix's harassment. Phoenix's abilities also constantly drain its own health away, becoming more vulnerable to Poison Attack.

* Earthbind can prevent Phoenix from using Icarus Dive, the only escaping mechanism of this hero.
* Heavy burst damage from Poof can easily kill Phoenix even when it slows down all the Meepos with Fire Spirits.
* Meepo's clones destroy the Phoenix Sun from Supernova in no time, even when they are slowed down by Fire Spirits.
* Meepo's naturally high magic resistance gives Phoenix a hard time with bursting him down. He can even turn the tide if Icarus Dive is on cooldown.
Additional:
* Meepo is unlike any other multi-unit enemy Phoenix may face in the battlefield. Unlike illusion-based heroes like Phantom Lancer or Chaos Knight, Meepo's clones are not illusions, meaning they can deal full damage to the Phoenix Sun if all four (or five) are present.

* Viper Strike breaks Multicast.
* Corrosive Skin minimizes the damage from Ignite and Fireblast.

* Ogre Magi has single-targeted magical-only damage and disables and is less effective against Meepo's clones.

* The damage over time from Viper's Poison Attack and Viper Strike rapidly wear down Refraction charges, allowing Templar Assassin to be damaged. Additionally, Corrosive Skin causes her attacks to apply damage overtime on her as well.
* Nethertoxin is a big threat to Templar Assassin. Her initially low range making it very hard to deal against Nethertoxin in the laning phase. At any stage of the game, a Nethertoxin can always force her to undo her Meld.
Additional:
* All of Viper's abilities quickly burn through Refraction charges.
* Templar Assassin's short range, aside from Psi Blades' spill damage, makes her vulnerable to Poison Attack harassment.
* Templar Assassin usually buys health and armor items for damage. Outside of Black King Bar, Viper will almost always be able to kill her when Refraction is down.

* Multiple attackers thanks to summoned units or clones: Meepo, Witch Doctor, Lycan, Enigma, Shadow Shaman
* Heroes that can quickly deal damage to her, regardless of how weak they are, can easily break through her Refraction:
* Multiple attackers thanks to summoned units or clones: Meepo, Witch Doctor, Lycan, Enigma, Shadow Shaman
* Multiple attackers thanks to illusions: Phantom Lancer, Chaos Knight, Naga Siren (bonus for her Ensnare). Also despite the visual effects, Templar Assassin does not spill damage against illusions or buildings, so she is not a really good hero to clean up illusions.
* Weak damage but high tick rate or persist in a long time: Slark, Gyrocopter, Queen of Pain, Shadow Shaman (Shackles), Jakiro, Pugna, Doom

* Nethertoxin disable passives, negating Spectre's damage and survivability by removing both Dispersion and Desolate.
* Due to Haunt and Radiance's burn, Spectre is heavily susceptible to being persistently slowed and damaged by Corrosive Skin without even directly attacking Viper.
* Poison Attack and Viper Strike further slow Spectre's movement speed to a crawl, while his improved magic resistance means he can easily shrug off Radiance's burn.
Additional:
* Viper Strike can disable Desolate and Dispersion, leaving Spectre with far less damage output and damage mitigation in engagements.
* Spectre is one of the weakest heroes at early levels. Viper can stifle her farm with early fights before Spectre purchases any major items.

* Spectre's Haunt with Radiance may be useful for countering Meepo but if Meepo finds the real one, Spectral Dagger is useless. Non-Black King Bar heroes like her will suffer from all of Meepo's abilities. Meepo is also a very large counter as Spectre takes a long time to come online, normally farming in the jungle or in lane, which makes her an easy target for Meepo ganks.

Additional:
* Poof combined with Earthbind can be used to easily lockdown and burst Spectre down.
* As Meepo's playstyle is often to come online early to mid game and take over the whole game, Meepo will often be much further ahead of Spectre in farming.
* Meepo's global map presence allows him to effectively hunt for Spectre and disrupt her farm.
* Spectre has no strong AOE abilities or way to control or lock down Meepo.

* Viper's Nethertoxin disables Cloak and Dagger, negating Riki's invisibility and much of his damage. It also makes him more vulnerable to magic damage, which does not go well with Riki's low health pool. With the talent applied, he can't even blink to safety or hide with Tricks of the Trade.
* Corrosive Skin makes it hard for Riki to chase Viper and attack him due to the attack speed slow.
* Viper Strike stays on Riki even after he goes invisible.
* Poison Attack makes it risky for Riki to get last hits and can make the laning phase difficult for him.

* Heroes with high mobility can be prevented from using it to their advantage with Earthbind, even if they pack a dangerous arsenal: Earth Spirit, Ember Spirit, Storm Spirit, Nature's Prophet, Phantom Assassin, Riki, Anti-Mage, Weaver.
* See items and abilities disabled by roots

Additional:
* Root is a deadly threat to Riki, disabling both Blink Strike and Tricks of the Trade while making him fully revealed, making Earthbind a good ability against him.
* Smoke Screen may not be able to silence all the Meepo clones.
* Riki has no true area damage, as Tricks of the Trade's damage is distributed between all Meepo clones, so he cannot effectively fight Meepo or deal with his strong ability to push unless Riki has Battle Fury.

* Viper Strike can disable Gravekeeper's Cloak, Visage's primary defense mechanism.
* Viper can ignore Grave Chill's attack speed slow with his magic damage output.
Additional:
* Since Visage is a slow hero, Viper can easily kite him with Poison Attack and Viper Strike while successfully chipping away at Gravekeeper's Cloak.
* Nethertoxin removes all layers of Gravekeeper's Cloak, leaving Visage exposed.
* Corrosive Skin makes Viper highly resistant to Soul Assumption.

* Heroes that can overwhelm Visage by sheer number like Chaos Knight, Meepo, Terrorblade and Phantom Lancer.

* Viper's skill set makes him an effective early game ganker against Anti-Mage before he is sufficiently farmed.
* Viper's Corrosive Skin and low mana pool causes him to take little damage from Mana Void.
* Nethertoxin disables Mana Break and Counterspell, weakening both his offense and defense.

* Multiple Earthbinds allows Meepo to lock down Anti-Mage almost indefinitely.
* Meepo's clones can only use their mana for Poof, keeping their mana pool nearly full and thus making them a bad target for a Mana Void.
Additional:
* Earthbind can prevent Anti-Mage from using Blink, allowing Meepo to kill him with attacks and Ransack.

* Poison Attack makes it hard for Void Spirit to lane against him.
* Corrosive Skin reduces the magical damage from Void Spirit's spells.

* Meepo's Earthbind can easily lockdown Void Spirit.
* Meepo and his clones can easily burst Void Spirit's Resonant Pulse.

* Heroes with Break abilities will prevent Slark from regenerating and gaining Essence Shift stacks: Viper, Shadow Demon, etc.

Additional:
* Viper Strike can disable Essence Shift and the regeneration aspect of Shadow Dance.
* Dark Pact doesn't mean a lot against Viper's ubiquitous slows.
* Viper becomes a relevant presence in team fights before Slark can procure his standard items (e.g. Shadow Blade).

* Slark's Dark Pact and Pounce can deny only one Earthbind and Poof can penetrate Shadow Dance if he doesn't build Black King Bar.

Additional:
* Earthbind and Poof will still hit Slark in Shadow Dance.
* Dark Pact can only remove one Earthbind.
* Ransack will still affect Slark, even if he has a Black King Bar.

* Heroes that can apply early pressure before Phantom Assassin has farm are massive threats: Axe, Viper, Meepo, Jakiro, Pugna, Slark, Venomancer etc.

* Heroes with high mobility can be prevented from using it to their advantage with Earthbind, even if they pack a dangerous arsenal: Earth Spirit, Ember Spirit, Storm Spirit, Nature's Prophet, Phantom Assassin, Riki, Anti-Mage, Weaver.
* See items and abilities disabled by roots

* Heroes with break can disable Untouchable for a while: Doom and Shadow Demon (via Aghanim's Scepter), Viper, Shadow Shaman with Hex Breaks talent.

* Meepo can quickly kill Enchantress with a Poof combo, rendering Untouchable useless.

* In the early game, a Dragon Knight without Black King Bar is basically defenseless against Viper.
* Viper can harass Dragon Knight at any time with his Poison Attack and Nethertoxin.
* Corrosive Skin reduces damage from Dragon Fire and inflicts damage to him.
* Viper Strike disables Dragon Blood, negating his main survivability.
* Viper Strike and Poison Attack can severely slow him down even with his Elder Dragon Form.
Additional:
* Dragon Knight is easily harassed by Poison Attack after the laning stage ends.
* Corrosive Skin protects Viper from Breathe Fire and returns damage.
* Viper Strike can disable Dragon Blood, Dragon's Knight main source of armor and health regeneration.
* Between Poison Attack and Viper Strike, Viper can keep Dragon Knight permanently slowed even in Elder Dragon Form.

* Viper Strike breaks Sniper's passives.
* Corrosive Skin allows Viper to deal more damage to Sniper than Sniper deals to him when laning, especially by briefly stepping into Shrapnel.
* Nethertoxin together with Poison Attack can slow Sniper and tears through his low health and mobility.

* His Poison Attack is very useful against Huskar, since he tends to stay at low health.
* Nethertoxin disables passive skills like Berserker's Blood.
* It is dangerous for Huskar to jump on Viper because Corrosive Skin and Viper Strike with the slowdown of movement and attack speed which usually will be deadly for Huskar.
Additional:
* Viper Strike can disable Berserker's Blood, which Huskar relies upon for attack speed and healing.
* The damage from Burning Spear and Life Break is largely absorbed by Corrosive Skin. It also will return some damage, making it risky to use Burning Spears in the laning stage.
* Because Huskar wants to be on low health for Berserker's Blood, he is particularly vulnerable to Poison Attack.

* Chain of Earthbinds prevents her from using Blink, allowing Meepo to quickly kill her with Poof and attacks.
* Meepo tends to buy items with attributes, mitigating Queen of Pain's magical burst.
Additional:
* Meepo is the hard counter for Queen of Pain - chaining Earthbinds prevents her from using Blink for a long time, and without any other escape options, Queen of Pain cannot survive several Poofs and attacks.
* Meepo tends to build items with attributes, mitigating Queen of Pain's magical burst.

* Nethertoxin disables Dawnbreaker's Luminosity. Since she's a melee hero, she needs to close gap to attack and Nethertoxin will be bad for her since she cannot heal.
* Viper Strike and Poison Attack will severely slow her down and combined with Nethertoxin, it will be her death sentence (unless her Celestial Hammer or Solar Guardian are off cooldown). Besides that, chasing her down will be easy due to the slow.

* Viper's Poison Attack and Viper Strike that can slow Razor, and is one of the few heroes that can keep him immobile.
* Altogether, Viper's skills reduce Razor's attack speed, heavily reducing the benefit of the damage drain from Static Link.
Additional:
* Storm Surge is counteracted by Viper Strike, leaving Razor without his extra movement speed.
* Static Link's damage drain doesn't bother Viper a lot as most of his early to mid game damage is magical.

* Corrosive Skin minimizes the damage from Impale and Mind Flare, and anything else Nyx Assassin tries to throw at Viper.
* Nyx Assassin cannot survive several poison damage-over-time output from Poison Attack, Nethertoxin, Corrosive Skin and Viper Strike, not even while he has Spiked Carapace active. And to make things worse, Nyx Assassin is not a common Silver Edge wielder to counter this problem at all.
Additional:
* Corrosive Skin minimizes the damage from Impale and Mind Flare, and anything else Nyx Assassin tries to throw at Viper.
* Nyx Assassin cannot survive several poison damage-over-time output from Poison Attack, Nethertoxin, Corrosive Skin and Viper Strike, not even while he has Spiked Carapace active. And to make things worse, Nyx Assassin is not a common Silver Edge wielder to counter this problem at all.

* Heroes that can slow Charge of Darkness by a huge amount: Venomancer, Viper, Dazzle, Arc Warden, Lion, Huskar, Shadow Shaman, Visage, Undying, Jakiro.

* Earthbind's root prevents/interrupts Charge of Darkness.
* As a single-target focused hero without much damage output, Spirit Breaker is ineffective in general against Meepo.

* Corrosive Skin minimizes the damage Viper takes from all of Ancient Apparition's abilities.
* Ancient Apparition's slow movement speed, squishy nature, and lack of escape abilities can easily be taken advantage of through Poison Attack and Viper Strike.

* Corrosive Skin minimizes the damage Viper takes from all of Disruptor's skills.

* Poof will destroy Shadow Demon's illusions created by Disruption and quickly escapes from Shadow Poison & Demonic Purge.

* Viper's poison abilities can slow Bounty Hunter's movement speed and allows to chase him with True Sight items.
* Nethertoxin can break Jinada, and the silence from level 25 prevents Bounty Hunter from using all of his spells.

* Viper Strike is a strong and breaks Fury Swipes, undispellable slow, making it much easier to kite Ursa for everyone.

* Because Poison Attack has almost no cooldown, Aphotic Shield is ineffective as a hard dispel.
* Viper Strike can prevent Borrowed Time from activating passively and block Curse of Avernus.
Additional:
* Because Poison Attack has almost no cooldown, Aphotic Shield is ineffective as a hard dispel.
* Viper Strike can prevent Borrowed Time from activating passively and block Curse of Avernus.

* Hand of God has a long cooldown, so damage over time spells can be hazardous for Chen, forcing him to use it prematurely: Jakiro, Venomancer, Viper, Dazzle, Phoenix.

* Heroes with high movement speeds like Pugna and Meepo can run around, to, or away from Snapfire during Mortimer Kisses and dodge the projectiles easily due to their slow speed.
* Heroes with mobility spells (such as Queen of Pain's Blink and Clockwerk with Hookshot) can easily avoid Lil' Shredder and Mortimer Kisses.
* Heroes with high movement speeds like Pugna and Meepo can run around, to, or away from Snapfire during Mortimer Kisses and dodge the projectiles easily due to their slow speed.

* Mirana cannot use Leap while rooted by Earthbind and her Moonlight Shadow is countered by Meepo's true sight that is provided by Earthbind.

Additional:
* Earthbind prevents Mirana from Leaping or going invisible with Moonlight Shadow. She can be easily killed by Poof and Ransack while disabled.
* Landing a Sacred Arrow on Meepo does not render him helpless, as all of the other Meepos can still fight back.

* Heroes who can easily harass Crystal Maiden out of lane in the early game (Clinkz, Viper) can prevent Crystal Maiden from being able to level effectively, and can ultimately slow down her level 6, 12, and 18 to a point where enemy carries already have items to address her ultimate.

* Heroes with damage-increasing passive abilities, such as Viper and Riki, will usually kill Silencer in a short time before he even has time to set up his abilities.

* Juggernaut's Omnislash is meaningless for Meepo who can share the damage across clones to save other allies.

* Viper can bully Alchemist out of mid lane quite easily, forcing him to either retreat into jungle, or stay harassed in lane, and get very few last hits. Vipers break also completely disables Greevil's greed which prevents Alchemist to earn his amazing amounts of money.

* Skywrath Mage's abilities are single targeted and he can't use Mystic Flare to its fullest potential, since all Meepos spread the damage between them. He also has no disables to prevent Meepo from Poofing to another one (unless he can get Ancient Seal off first).

* Heroes with high mobility can be prevented from using it to their advantage with Earthbind, even if they pack a dangerous arsenal: Earth Spirit, Ember Spirit, Storm Spirit, Nature's Prophet, Phantom Assassin, Riki, Anti-Mage, Weaver.
* See items and abilities disabled by roots

* Meepo can quickly destroy Tombstone thanks to Divided We Stand.

* Night Stalker's most skills are single targeted which allows other Meepos to Poof, Earthbind and kill him.

* Melee heroes with low mobility can be kited and killed by Viper: Treant Protector, Kunkka, Alchemist, Troll Warlord, Wraith King, Tiny, Sven.

* Heroes who can harass Omniknight out of lane will keep him weak in the mid game: Viper, Venomancer, Clinkz.

* The slow applied from Corrosive Skin offsets the movement speed bonus granted by Scorched Earth and the tick-based damage from Infernal Blade and Doom will continually slow Doom down. This allows Viper, much like Sniper, to 'kite' Doom and keep him at a safe distance between the two. Additionally, Corrosive Skin applies an attack-speed slow which is fairly crippling to a hero such as Doom that, naturally, has a high base attack-time, poor agility gain and builds little attack-speed items.
* Since Doom does not disable auto-cast abilities, Viper's Poison Attack will continue to work. Doom may find it hard to close the distance between himself and Viper, and thusly difficult to effectively lockdown and continually deal damage through his abilities.

* Viper wins on the central line of Puck, because he has a huge damage from the Poison Attack ability, which Puck is not able to constantly avoid using Phase Shift, which will give Viper an advantage in the possible damage inflicted on each other
* Puck takes more damage than it does due to the passive Corrosive Skin ability of the Viper, which makes it unprofitable for the Puck to fight against the Viper at an early stage of the game, when the Puck has a very small pool of health.
Additional:
* Viper wins on the central line of Puck, because he has a huge damage from the Poison Attack ability, which Puck is not able to constantly avoid using Phase Shift, which will give Viper an advantage in the possible damage inflicted on each other
* Puck takes more damage than it does due to the passive Corrosive Skin ability of the Viper, which makes it unprofitable for the Puck to fight against the Viper at an early stage of the game, when the Puck has a very small pool of health

* Tiny has low movement speed and attack speed, making him vulnerable to Viper's slows.
* Corrosive Skin provides magic resistance to lower Tiny's magic burst damage.

* Slardar does not do well against multiple targets, as his only way to damage multiple targets is Slithereen Crush.
* Meepo's Earthbind will root Slardar, making him unable to chase/escape for the time being. Also, Poof's low cooldown and high damage can burst Slardar down rather quickly.

* Nethertoxin both Necromastery and Presence of the Dark Lord, reducing his damage massively.
* Corrosive Skin gives Viper bonus Magic Resistance against Shadowraze and Requiem of Souls.
* Viper can easily take advantage of Shadow Fiend's lack of escape and mobility spells with Viper Strike breaks and Poison Attack. Poison Attack also serves as a great way to harass Shadow Fiend.

* Viper STrike cancels out Kraken Shell and stops the hard dispel from passively activating, preventing Tidehunter from functioning as a frontline tank.
* Anchor Smash is mostly irrelevant against a ranged hero like Viper.
* Tidehunter relies on the threat of Ravage, which has an obscenely long cooldown. Viper can exploit the downtime with his short cooldowns.

* With all 5 Meepos available, all of Shaman's wards will be disposed of very quickly.
* All of Shaman's disables are based around single target control, and he can at most only disable two Meepos, allowing the rest to easily lay waste to him, be it during the channel duration of Shackles or by using Earthbind.

* Poison Attack and Viper Strike slows Axe significantly, and puts his Blink Dagger on cooldown, preventing him from initiating. Viper Strike can also break from Counter Helix.
Additional:
* Viper Strike prevents Counter Helix from triggering, which significantly lowers Axe's damage output in the early to mid game.
* Viper's various slows and damage over time prevents Axe from initiating as well as putting his Blink Dagger on cooldown.

* Flux is severely impaired against Meepo because of Divided We Stand.
* Meepo's farming speed and early powerspikes allows him to pressure Arc Warden before he is capable of fighting effectively.
* Without Black King Bar, Earthbind and Poof can finish Arc Warden quickly before he has time to do much.

* Melee heroes with low mobility can be kited and killed by Viper: Treant Protector, Kunkka, Alchemist, Troll Warlord, Wraith King, Tiny, Sven.

* Meepo has a better advantage in farm with Divided We Stand, as well as having a higher attack speed due to his tendency to build items that give attributes. In addition, Wraithfire Blast stuns only one target, and choosing to engage one Meepo will most certainly mean engaging them all.

* Earthbind disables Waveform, effectively keeping Morphling in place for an extended period of time, allowing Meepo to deal considerable damage with Poof.

* Poof will destroy Phantom Lancer's illusions within a short time.
* Earthbind prevents Phantom Lancer from using Doppelganger.
Additional:
* Poof from multiple Meepos will destroy illusions quickly.
* Earthbind's area root can catch Phantom Lancer in a group of illusions and prevent him from using Doppelganger for a long time.
* Meepo aims to end the game as early as possible, while Phantom Lancer is a lategame hero.
* This also means that, in the late game, Meepo stands no chance against Phantom Lancer.

* Corrosive Skin will protect Viper from Techies' magical damage.
* Even though Reactive Tazer will disarm Viper if he attacks Techies with Poison Attack, he does lots of damage with his other abilities that can still kill Techies.

* Nethertoxin prevents the buildup of Jingu Mastery stacks.
* Viper's poison magical damage-over-time stops Monkey King from using Tree Dance. It also ignores the extra armor bestowed by Wukong's Command.
Additional:
* Viper STrike prevents the buildup of Jingu Mastery stacks.
* Monkey King's high base movement speed is of little worth against the array of slows Viper possesses.
* All of Viper's magical damage over time stops Monkey King from using Tree Dance. It also ignores the extra armor bestowed by Wukong's Command.

* Corrosive Skin means Viper can often outlast Venomancer in a battle of attrition.
* Venomancer has no mobility without items, which makes him vulnerable to constant slows.

* Nethertoxin disables Bristleback's passive.
* Viper Strike and Poison Attack slow down Bristleback's movement speed, making him unable to get out from Nethertoxin.
Additional:
* Viper Strike can disable Bristleback and prevents Warpath from building stacks. Besides losing his defensive passive, Bristleback also loses his ability to build up damage over lengthy battles.
* Viper can perpetually kite Bristleback with Poison Attack and Viper Strike.

* Nethertoxin breaks the damage block from Bulwark.
* Poison Attack and Viper Strike's slows make it difficult for Mars to contribute to fights due to his low mobility.
Additional:
* Viper Strike can disable Bulwark entirely, making Mars far less tanky. Using Nethertoxin inside Arena of Blood may discourage enemies from following up with Mars's initiation.
* Rod of Atos is currently common on Viper and keeps Mars in position long enough to be killed.
* However, Viper is not very tanky earlier in the game, so positioning against Mars is important for Viper since a well-timed Spear of Mars can be the end of Viper.

* Nature's Prophet is heavily countered by Meepo, not only Meepo can kill the treants with a single Poof, but he can also stop Nature's Prophet from using Teleportation, and can gain vision inside Sprout.

Additional:
* Meepo can net Nature's Prophet's treants with Earthbind and then Poof them, putting an end to his pushing.
* Skilled Meepos can rival and even exceed Nature's Prophet's global presence by combining Poof with Boots of Travel, meaning that he can not only stop his push, but also can kill him if he is not careful.

* Earthbind, like any root, inhibits usage of Ball Lightning, eliminating Storm Spirit's mobility.

* Viper Strike prevents Timbersaw from gaining stacks on Reactive Armor.

* Melee heroes with low mobility can be kited and killed by Viper: Treant Protector, Kunkka, Alchemist, Troll Warlord, Wraith King, Tiny, Sven.

* Poison Attack and Viper Strike allowing to kite and slow Earthshaker significally, putting Blink Dagger on cooldown and preventing him from initiating or re-initiating.
* Nethertoxin breaks Aftershock. The silence from Level 25 talent also prevents Earthshaker from initiating or re-initiating.
Additional:
* Being a melee hero, Earthshaker's movement is liable to suppression by Poison Attack and Viper Strike.
* Earthshaker's kit, with the exception of Enchant Totem, deals magic damage. Corrosive Skin effectively blunts his killing potential with a standard Blink combo among other things.
* Viper Strike can disable Aftershock, which removes the stun and bonus damage from Enchant Totem and Echo Slam.

* Viper Strike prevents buildup of Fiery Soul stacks.
* Corrosive Skin provides magic resistance against Lina's spells. However, Lina can counter this with Silver Edge, a common item on Lina.
* Poison Attack and Viper Strike can burn away Lina's small health pool.

* Earthbind prevents Broodmother from escaping Meepo's attacks.
* Poof will quickly clear any nearby spiders.
* Broodmother often picks off single target heroes. With Meepo's Divided We Stand, it gets a lot harder once every Meepo Poofs in.

* When Legion Commander uses Duel on one Meepo, he can use his other Meepos to kill her. If he wasn't dueled, he can help the teammate who was duelled to give the teammate the damage instead of Legion Commander.
* However, if Legion Commander picked up an Aghanim's Scepter and she duels one Meepo, that might be the end of Meepo if Legion managed to gather enough damage from previous duels.

* Nethertoxin disables Vengeance Aura.
* Vengeful Spirit has no mobility spells aside from Nether Swap, which Viper can take advantage of with his slows.
* Viper can easily bully Vengeful Spirit out of a lane with Poison Attack.
Additional:
* Viper Strike can disable the attack damage bonus from Vengeance Aura and the components of Nether Swap.
* Both Magic Missile and Wave of Terror are counteracted by Corrosive Skin, making Vengeful Spirit's fighting harder against Viper.