* Heroes that create illusions: Spectre, Shadow Demon, Phantom Lancer, Naga Siren, Chaos Knight, Terrorblade) or bring other units into the fight (such as Nature's Prophet, Lone Druid, Chen, Enchantress, Meepo and Arc Warden) can cause Eclipse to strike the illusions/summons unintentionally. However, in many cases Moon Glaives can resolve this issue and eliminate them before activating Eclipse, but that will require lots of farming for right-click items.

* Since Windranger is bad against magical damage, heroes with continuous magical damage or magical nukes can blast her: Zeus, Tinker, Leshrac, Viper, Skywrath Mage, Lion, Lina, Venomancer.

* Song of the Siren lasts long enough to prevent a successful Duel (but only if Naga wasn't the target).

* Illusion heroes, such as Naga Siren, Phantom Lancer, Chaos Knight, Terrorblade will become strong against Tinker in the late game. Without Aghanim's Scepter Tinker is forced to defensively disarm heroes with Laser, leaving illusions free to deal physical damage which Tinker's low armor makes highly effective. In addition, Mjollnir or Battle Fury, two common pickups against illusion heroes, don't work well on Tinker at all.

* Heroes that build Diffusal Blade or can fit it well into their item build will also make Medusa much less tanky: Riki, Naga Siren, Terrorblade, Juggernaut, Spectre, Slark.

* Heroes with strong area-of-effect damaging and/or disabling abilities will be able to intercept Underlord and his team when they exit from Fiend's Gate: Luna's Aghanim's Scepter upgraded Eclipse, Dawnbreaker's Solar Guardian, Axe's Berserker's Call, Mars's Arena of Blood, Jakiro's Macropyre, Dual Breath and Ice Path, Naga Siren's Song of the Siren, Razor's Eye of the Storm and Plasma Field, Lina's Light Strike Array, Broodmother's Spinner's Snare from Aghanim's Scepter, Elder Titan's Earth Splitter and Echo Stomp, Alchemist's Unstable Concoction and Acid Spray, Queen of Pain's Sonic Wave, Dark Seer's Wall of Replica and Vacuum, Venomancer's Noxious Plague and Poison Nova from Aghanim's Scepter, Oracle's Fortune's End and Rain of Destiny from Aghanim's Shard, Bloodseeker's Blood Rite, Enigma's Black Hole and Midnight Pulse, Shadow Fiend's Requiem of Souls, Batrider's Aghanim's Scepter upgraded Flaming Lasso, Firefly, Flamebreak and Sticky Napalm, Ancient Apparition's Ice Blast, Sand King's Epicenter, Sand Storm and Burrowstrike, Gyrocopter's Call Down, Ember Spirit's Sleight of Fist, Death Prophet's Exorcism and Silence, Monkey King's Wukong's Command, Crystal Maiden's Freezing Field, Muerta's The Calling, Medusa's Stone Gaze, Zeus's Nimbus from Aghanim's Scepter. Dark Willow's Bramble Maze, Pangolier's Swashbuckle, Grimstroke's Soulbind, Ink Swell and Stroke of Fate, Earthshaker's Echo Slam and Fissure, Puck's Dream Coil and Waning Rift, Winter Wyvern's Winter's Curse, Magnus's Reverse Polarity.

* Heroes with illusions: Chaos Knight, Naga Siren, Phantom Lancer, Terrorblade

* Heroes with illusions and summons can swarm and overwhelm Bane, who has no area abilities to deal with them outside from Aghanim's Shard upgraded Brain Sap: Broodmother, Chaos Knight, Naga Siren, Nature's Prophet, Phantom Lancer, Terrorblade, Visage, Warlock, Wraith King.

* Illusion-based heroes are effective against Omnislash and Juggernaut's single-targeted damage: Naga Siren, Chaos Knight, Terrorblade,Phantom Lancer.

* Ensnare prevents using any kind of movement abiilties, Making Naga Siren good against heroes who rely on gap-closing abilities to escape: Phantom Assassin, Magnus, Slark, Riki, Faceless Void, Storm Spirit.

* Viper Strike breaks Sniper's passives.
* Corrosive Skin allows Viper to deal more damage to Sniper than Sniper deals to him when laning, especially by briefly stepping into Shrapnel.
* Nethertoxin together with Poison Attack can slow Sniper and tears through his low health and mobility.

* Ensnare with her attacks allows Naga Siren to gank Sniper easily.
* Rip Tide removes Sniper's very little armor.

* His Poison Attack is very useful against Huskar, since he tends to stay at low health.
* Nethertoxin disables passive skills like Berserker's Blood.
* It is dangerous for Huskar to jump on Viper because Corrosive Skin and Viper Strike with the slowdown of movement and attack speed which usually will be deadly for Huskar.
Additional:
* Viper Strike can disable Berserker's Blood, which Huskar relies upon for attack speed and healing.
* The damage from Burning Spear and Life Break is largely absorbed by Corrosive Skin. It also will return some damage, making it risky to use Burning Spears in the laning stage.
* Because Huskar wants to be on low health for Berserker's Blood, he is particularly vulnerable to Poison Attack.

* Mirror Image can cause Huskar to Life Break the wrong target.
* Rip Tide reduces Huskar's already low armor.
* Song of the Siren allows teams to recover from Huskar's initiation, as well as the damage over time from Burning Spears.

* Because Poison Attack has almost no cooldown, Aphotic Shield is ineffective as a hard dispel.
* Viper Strike can prevent Borrowed Time from activating passively and block Curse of Avernus.
Additional:
* Because Poison Attack has almost no cooldown, Aphotic Shield is ineffective as a hard dispel.
* Viper Strike can prevent Borrowed Time from activating passively and block Curse of Avernus.

* Song of the Siren completely wastes Abaddon Borrowed Time while keeping him in place.
* Naga Siren is able to simply dispel Abaddon's Curse of Avernus with Mirror Image before getting hit 4 times consecutively.
* Although Naga Siren's illusions can be easily destroyed by Aphotic Shield, Naga Siren can resolve that issue easily by purchasing Heart of Tarrasque to drastically increase her durability. Plus, the said item makes Naga Siren harder to be distinguished from her illusions.

* Hand of God has a long cooldown, so damage over time spells can be hazardous for Chen, forcing him to use it prematurely: Jakiro, Venomancer, Viper, Dazzle, Phoenix.

* Naga Siren can make landing Chen's combo very hard due to her being an illusion hero thanks to Mirror Image.
* Rip Tide can deal big damage to Chen and reduce Chen's armor, as well as easily kill all of Chen's creeps.
* Naga Siren often builds Radiance, which allows her to quickly clear Chen's creeps.
* Ensnare will prevent Chen from escaping.
* With Aghanim's Scepter, Naga Siren can get access to Reel In, which can separate Chen from his creeps and draw him closer to Naga Siren and her team to finish her off. To make things worse, Chen has no way to cancel Reel In on his own, and must rely on outside from {U:Centaur Conqueror} or {U:Mud Golem} under his control.
* Carry or Nuker Naga Siren can often finish off Support Chen before he can have a chance to activate Hand of God.
Additional:
* Naga Siren can make landing Chen's combo very hard due to her being an illusion hero.
* Rip Tide can deal big damage to Chen and reduce Chen's armor, as well as easily kill all of Chen's creeps.
* Naga Siren often builds Radiance, which allows her to quickly clear Chen's creeps.
* Ensnare will prevent Chen from escaping.
* With Aghanim's Scepter, Naga Siren can get access to Reel In, which can separate Chen from his creeps and draw him closer to Naga Siren and her team to finish her off. To make things worse, Chen has no way to cancel Reel In on his own, and must rely on outside from {U:Centaur Conqueror} or {U:Mud Golem} under his control.
* Carry or Nuker Naga Siren can often finish off Support Chen before he can have a chance to activate Hand of God.

* Corrosive Skin will protect Viper from Techies' magical damage.
* Even though Reactive Tazer will disarm Viper if he attacks Techies with Poison Attack, he does lots of damage with his other abilities that can still kill Techies.

* Heroes with summons like Broodmother, Enigma, Nature's Prophet; or illusions, like Naga Siren, Terrorblade are effective at keeping the choke points and rune spawns safe from Proximity Mines.

* Heroes who can easily harass Crystal Maiden out of lane in the early game (Clinkz, Viper) can prevent Crystal Maiden from being able to level effectively, and can ultimately slow down her level 6, 12, and 18 to a point where enemy carries already have items to address her ultimate.

* Mirror Image can dispel Frostbite. A similar effect can be achieved with Manta Style, a core item on Naga Siren.
* Song of the Siren can stop Freezing Field regardless of any kind of invisibility as well as allow Naga Siren's team to quickly close the gap on Crystal Maiden.
* With Aghanim's Scepter, Naga Siren can get access to Reel In ability, which can allow her to pull Crystal Maiden toward herself and her team and cancel Freezing Field even through Black King Bar.
Additional:
* Mirror Image can dispel Frostbite.
* Song of the Siren can stop Freezing Field regardless of any kind of invisibility as well as allow Naga Siren's team to quickly close the gap on Crystal Maiden.
* Ensnare allows Naga Siren and her team to quickly catch up with Crystal Maiden and kill her.
* With Aghanim's Scepter, Naga Siren can get access to Reel In ability , which can allow her to pull Crystal Maiden toward herself and her team and cancel Freezing Field even through Black King Bar.

* Viper does large amounts of magic damage over time, meaning that if a Necrophos uses Ghost Shroud, Viper's abilities will greatly reduce Necrophos survivability, and may actually kill him.
* By the same token, Viper can use his Viper Strike on Necrophos if he attempts to heal himself with Ghost Shroud, and depending on any other effects Necrophos may have from him, (IE:Poison Attack,Corrosive Skin), Viper can often kill Necrophos while he is in his Ghost Shroud.
* Viper's Corrosive Skin helps him take reduced damage from all of Necrophos spells that deal magical damage, which is his only source of damage.
Additional:
* Viper Strike prevents Heartstopper Aura from dealing damage or healing Necrophos.
* Viper's magic damage is amplified whenever Ghost Shroud is used.
* Corrosive Skin makes Viper tankier against Death Pulse and Reaper's Scythe.

* Illusions make it difficult for Necrophos to target his Reaper's Scythe correctly, thus giving illusion heroes like Chaos Knight or Naga Siren an edge against Necrophos.

* Viper's Nethertoxin disables Cloak and Dagger, negating Riki's invisibility and much of his damage. It also makes him more vulnerable to magic damage, which does not go well with Riki's low health pool. With the talent applied, he can't even blink to safety or hide with Tricks of the Trade.
* Corrosive Skin makes it hard for Riki to chase Viper and attack him due to the attack speed slow.
* Viper Strike stays on Riki even after he goes invisible.
* Poison Attack makes it risky for Riki to get last hits and can make the laning phase difficult for him.

* Ensnare prevents using any kind of movement abiilties, Making Naga Siren good against heroes who rely on gap-closing abilities to escape: Phantom Assassin, Magnus, Slark, Riki, Faceless Void, Storm Spirit.

* Corrosive Skin minimizes the damage from Impale and Mind Flare, and anything else Nyx Assassin tries to throw at Viper.
* Nyx Assassin cannot survive several poison damage-over-time output from Poison Attack, Nethertoxin, Corrosive Skin and Viper Strike, not even while he has Spiked Carapace active. And to make things worse, Nyx Assassin is not a common Silver Edge wielder to counter this problem at all.
Additional:
* Corrosive Skin minimizes the damage from Impale and Mind Flare, and anything else Nyx Assassin tries to throw at Viper.
* Nyx Assassin cannot survive several poison damage-over-time output from Poison Attack, Nethertoxin, Corrosive Skin and Viper Strike, not even while he has Spiked Carapace active. And to make things worse, Nyx Assassin is not a common Silver Edge wielder to counter this problem at all.

* Nyx Assassin's skillset is mostly single-targeted, therefore he will have difficulties against heroes with illusions and summons: Naga Siren, Broodmother, Lycan, Visage, Phantom Lancer. And to make things worse, Nyx Asassin is not a common Battle Fury, Maelstrom, Mjollnir, Gleipnir or Radiance wielder to counter this problem.

* Corrosive Skin minimizes the damage Viper takes from all of Disruptor's skills.

* Naga Siren with Mirror Image
* Heroes that can dodge Glimpse:
* Puck with Phase Shift
* Riki with Tricks of the Trade
* Phantom Lancer with Doppelganger
* Ember Spirit with Sleight of Fist and Activate Fire Remnant
* Chaos Knight with Phantasm
* Naga Siren with Mirror Image
* Tusk with Snowball
* Juggernaut with Omnislash
* Brewmaster with Primal Split
* Lifestealer with Infest
* Phoenix with Supernova

* Viper's poison abilities can slow Bounty Hunter's movement speed and allows to chase him with True Sight items.
* Nethertoxin can break Jinada, and the silence from level 25 prevents Bounty Hunter from using all of his spells.

* Naga Siren with Mirror Image
* Heroes that can remove the Track debuff with their skills:
* Abaddon with Aphotic Shield and Borrowed Time
* Huskar with Life Break
* Juggernaut with Blade Fury
* Legion Commander with Press the Attack
* Lifestealer with Rage and Infest
* Naga Siren with Mirror Image
* Omniknight with Heavenly Grace
* Oracle with Fortune's End and False Promise
* Phantom Lancer with Doppelganger
* Slark with Dark Pact
* Ursa with Enrage
* Weaver with Time Lapse
* Tidehunter with Kraken Shell when damage received reaches the threshold.

Additional:
* Bounty Hunter is a single target damage dealer, so he will not fare well against Naga Siren. Even though Bounty Hunter can use Track on her, Mirror Image will dispel the effect. Ensnare also reveals invisible units while they're rooted, putting Bounty Hunter at a disadvantage.

* Heroes who can harass Omniknight out of lane will keep him weak in the mid game: Viper, Venomancer, Clinkz.

* Even though Naga Siren relies on direct attacks to deal damage for most of the time, Song of the Siren allows her to easily waste Guardian Angel.
* Ensnare fully works on targets affected with Heavenly Grace. However, Ensnare is dispellable with any dispel, and so can be dispelled by Heavenly Grace.
* As an agility hero that relies on illusions, Naga Siren is one of the most natural Diffusal Blade carriers, the bane of every hero with a small mana pool. Naga Siren can also buy items that deal magical damage like Radiance, Dagon, Ethereal Blade, Revenant's Brooch, Veil of Discord and Gleipnir to attack Omniknight's allies protected with Guardian Angel.
Additional:
* Although Naga Siren relies mostly on physical damage, Song of the Siren can be used to time out Guardian Angel, giving Naga Siren's team an easy opportunity to counter-initiate.
* Radiance allows it's owner to deal magical damage to multiple enemy heroes at once, and since Naga Siren often buys it, Guardian Angel is not a very good ability for protection against Naga Siren.
* Likewise, Nuker build Naga Siren (which primarly consists of items such as Radiance, Ethereal Blade, Dagon and Veil of Discord) can render Guardian Angel useless. Although Nuker is not a role Naga Siren should be playing.

* The damage over time from Viper's Poison Attack and Viper Strike rapidly wear down Refraction charges, allowing Templar Assassin to be damaged. Additionally, Corrosive Skin causes her attacks to apply damage overtime on her as well.
* Nethertoxin is a big threat to Templar Assassin. Her initially low range making it very hard to deal against Nethertoxin in the laning phase. At any stage of the game, a Nethertoxin can always force her to undo her Meld.
Additional:
* All of Viper's abilities quickly burn through Refraction charges.
* Templar Assassin's short range, aside from Psi Blades' spill damage, makes her vulnerable to Poison Attack harassment.
* Templar Assassin usually buys health and armor items for damage. Outside of Black King Bar, Viper will almost always be able to kill her when Refraction is down.

* Ensnare disables Templar Assassin's invisibility and Blink Dagger (a core item on Templar Assassin), and her illusions will break Refraction easily.

* Corrosive Skin gives Viper additional resistance to Phoenix's magical damage, and since they deal damage over time, Phoenix would be constantly afflicted by his passive's own debuff, making him not an ideal target for Phoenix's harassment. Phoenix's abilities also constantly drain its own health away, becoming more vulnerable to Poison Attack.

* Song of the Siren does not affect Supernova, which allows her and her team to focus the egg while the enemy team is affected by sleep.
* Phoenix cannot use Icarus Dive for escaping when rooted by Ensnare.
* However, Phoenix has many area-of-effect abilities that allow him to clear Naga Siren's illusions from Mirror Image.

* Heroes with Break abilities will prevent Slark from regenerating and gaining Essence Shift stacks: Viper, Shadow Demon, etc.

Additional:
* Viper Strike can disable Essence Shift and the regeneration aspect of Shadow Dance.
* Dark Pact doesn't mean a lot against Viper's ubiquitous slows.
* Viper becomes a relevant presence in team fights before Slark can procure his standard items (e.g. Shadow Blade).

* Ensnare prevents using any kind of movement abiilties, Making Naga Siren good against heroes who rely on gap-closing abilities to escape: Phantom Assassin, Magnus, Slark, Riki, Faceless Void, Storm Spirit.

* Heroes that can apply early pressure before Phantom Assassin has farm are massive threats: Axe, Viper, Meepo, Jakiro, Pugna, Slark, Venomancer etc.

* Ensnare prevents using any kind of movement abiilties, Making Naga Siren good against heroes who rely on gap-closing abilities to escape: Phantom Assassin, Magnus, Slark, Riki, Faceless Void, Storm Spirit.

* Nethertoxin prevents the buildup of Jingu Mastery stacks.
* Viper's poison magical damage-over-time stops Monkey King from using Tree Dance. It also ignores the extra armor bestowed by Wukong's Command.
Additional:
* Viper STrike prevents the buildup of Jingu Mastery stacks.
* Monkey King's high base movement speed is of little worth against the array of slows Viper possesses.
* All of Viper's magical damage over time stops Monkey King from using Tree Dance. It also ignores the extra armor bestowed by Wukong's Command.

* The slow applied from Corrosive Skin offsets the movement speed bonus granted by Scorched Earth and the tick-based damage from Infernal Blade and Doom will continually slow Doom down. This allows Viper, much like Sniper, to 'kite' Doom and keep him at a safe distance between the two. Additionally, Corrosive Skin applies an attack-speed slow which is fairly crippling to a hero such as Doom that, naturally, has a high base attack-time, poor agility gain and builds little attack-speed items.
* Since Doom does not disable auto-cast abilities, Viper's Poison Attack will continue to work. Doom may find it hard to close the distance between himself and Viper, and thusly difficult to effectively lockdown and continually deal damage through his abilities.

* Corrosive Skin means Viper can often outlast Venomancer in a battle of attrition.
* Venomancer has no mobility without items, which makes him vulnerable to constant slows.

* Nethertoxin disables Bristleback's passive.
* Viper Strike and Poison Attack slow down Bristleback's movement speed, making him unable to get out from Nethertoxin.
Additional:
* Viper Strike can disable Bristleback and prevents Warpath from building stacks. Besides losing his defensive passive, Bristleback also loses his ability to build up damage over lengthy battles.
* Viper can perpetually kite Bristleback with Poison Attack and Viper Strike.

* Nethertoxin breaks the damage block from Bulwark.
* Poison Attack and Viper Strike's slows make it difficult for Mars to contribute to fights due to his low mobility.
Additional:
* Viper Strike can disable Bulwark entirely, making Mars far less tanky. Using Nethertoxin inside Arena of Blood may discourage enemies from following up with Mars's initiation.
* Rod of Atos is currently common on Viper and keeps Mars in position long enough to be killed.
* However, Viper is not very tanky earlier in the game, so positioning against Mars is important for Viper since a well-timed Spear of Mars can be the end of Viper.

* Viper wins on the central line of Puck, because he has a huge damage from the Poison Attack ability, which Puck is not able to constantly avoid using Phase Shift, which will give Viper an advantage in the possible damage inflicted on each other
* Puck takes more damage than it does due to the passive Corrosive Skin ability of the Viper, which makes it unprofitable for the Puck to fight against the Viper at an early stage of the game, when the Puck has a very small pool of health.
Additional:
* Viper wins on the central line of Puck, because he has a huge damage from the Poison Attack ability, which Puck is not able to constantly avoid using Phase Shift, which will give Viper an advantage in the possible damage inflicted on each other
* Puck takes more damage than it does due to the passive Corrosive Skin ability of the Viper, which makes it unprofitable for the Puck to fight against the Viper at an early stage of the game, when the Puck has a very small pool of health

* Nethertoxin disable passives, negating Spectre's damage and survivability by removing both Dispersion and Desolate.
* Due to Haunt and Radiance's burn, Spectre is heavily susceptible to being persistently slowed and damaged by Corrosive Skin without even directly attacking Viper.
* Poison Attack and Viper Strike further slow Spectre's movement speed to a crawl, while his improved magic resistance means he can easily shrug off Radiance's burn.
Additional:
* Viper Strike can disable Desolate and Dispersion, leaving Spectre with far less damage output and damage mitigation in engagements.
* Spectre is one of the weakest heroes at early levels. Viper can stifle her farm with early fights before Spectre purchases any major items.

* Nethertoxin both Necromastery and Presence of the Dark Lord, reducing his damage massively.
* Corrosive Skin gives Viper bonus Magic Resistance against Shadowraze and Requiem of Souls.
* Viper can easily take advantage of Shadow Fiend's lack of escape and mobility spells with Viper Strike breaks and Poison Attack. Poison Attack also serves as a great way to harass Shadow Fiend.

* Viper's Poison Attack and Viper Strike that can slow Razor, and is one of the few heroes that can keep him immobile.
* Altogether, Viper's skills reduce Razor's attack speed, heavily reducing the benefit of the damage drain from Static Link.
Additional:
* Storm Surge is counteracted by Viper Strike, leaving Razor without his extra movement speed.
* Static Link's damage drain doesn't bother Viper a lot as most of his early to mid game damage is magical.

* Viper STrike cancels out Kraken Shell and stops the hard dispel from passively activating, preventing Tidehunter from functioning as a frontline tank.
* Anchor Smash is mostly irrelevant against a ranged hero like Viper.
* Tidehunter relies on the threat of Ravage, which has an obscenely long cooldown. Viper can exploit the downtime with his short cooldowns.

* Corrosive Skin minimizes the damage Viper takes from all of Ancient Apparition's abilities.
* Ancient Apparition's slow movement speed, squishy nature, and lack of escape abilities can easily be taken advantage of through Poison Attack and Viper Strike.

* Ensnare and Song of the Siren can be used to cancel both, Tether and Relocate and to close the distance on Io.
* Rip Tide combined with illusions from Mirror Image often finish off Io before he can save himself with Tether or Relocate.
* Spirits's weak area-of-effect makes it a bad tool to deal with Naga Siren's illusions from Mirror Image.
* Once Naga Siren buys Aghanim's Scepter, she can gain access to Reel In, which not only allows her to cancel both, Tether and Relocate, but also to pull Io to herself and her team while he is affected with Ensnare, similarly to Batrider's Flaming Lasso.
* Aghanim's Shard upgraded Song of the Siren can also heal the hero Io and his Tethered targed try to gank.
Additional:
* Ensnare and Song of the Siren can be used to cancel both, Tether and Relocate and to close the distance on Io.
* Rip Tide combined with illusions from Mirror Image often finish off Io before he can save himself.
* Spirit's weak area-of-effect makes it a bad tool to deal with Naga Siren's illusions from Mirror Image.
* Once Naga Siren buys Aghanim's Scepter, she can gain access to Reel In, which not only allows her to cancel both, Tether and Relocate, but also to pull Io to herself and her team while he is affected with Ensnare, similarly to Batrider's Flaming Lasso.
* Aghanim's Shard upgraded Song of the Siren can also heal the hero Io and his tethered targed try to gank.

* Poison Attack makes it hard for Void Spirit to lane against him.
* Corrosive Skin reduces the magical damage from Void Spirit's spells.

* Viper Strike breaks Multicast.
* Corrosive Skin minimizes the damage from Ignite and Fireblast.

* Nethertoxin disables Vengeance Aura.
* Vengeful Spirit has no mobility spells aside from Nether Swap, which Viper can take advantage of with his slows.
* Viper can easily bully Vengeful Spirit out of a lane with Poison Attack.
Additional:
* Viper Strike can disable the attack damage bonus from Vengeance Aura and the components of Nether Swap.
* Both Magic Missile and Wave of Terror are counteracted by Corrosive Skin, making Vengeful Spirit's fighting harder against Viper.

* Unless Lone Druid purchases a Black King Bar for his Spirit Bear, Ensnare will easily kite the Spirit Bear.
* Song of the Siren allows Naga Siren and her team to completely bypass the Spirit Bear and hunt for the Lone Druid himself when starting a fight.
* Lone Druid's lack of innate AoE capabilities mean that Naga Siren's illusions have no problem against him.

* Mirror Image can be effective since Night Stalker cannot withstand fighting illusions. If he's unable to tell which Naga Siren is real, he will have a hard time landing his Void. However, if Night Stalker obtains an Aghanim's Scepter, the upgraded Void will hit and may even locate the real Naga Siren in fights.
Additional:
* Ensnare and Song of the Siren prevents Night Stalker from escaping and ganking during daytime or even nighttime.
* Rip Tide reduces Night Stalker's armor, making him easier to focus down.
* Mirror Image can be effective against Night Stalker, due to his single target abilities.

* Viper Strike can disable Gravekeeper's Cloak, Visage's primary defense mechanism.
* Viper can ignore Grave Chill's attack speed slow with his magic damage output.
Additional:
* Since Visage is a slow hero, Viper can easily kite him with Poison Attack and Viper Strike while successfully chipping away at Gravekeeper's Cloak.
* Nethertoxin removes all layers of Gravekeeper's Cloak, leaving Visage exposed.
* Corrosive Skin makes Viper highly resistant to Soul Assumption.

* Viper Strike is a strong and breaks Fury Swipes, undispellable slow, making it much easier to kite Ursa for everyone.

* Heroes with break can disable Untouchable for a while: Doom and Shadow Demon (via Aghanim's Scepter), Viper, Shadow Shaman with Hex Breaks talent.

* Any hero who can survive Magnus's initiations and manfight him: Huskar, Faceless Void, Weaver, Abaddon, Troll Warlord, Alchemist, Dragon Knight, Night Stalker, Viper.

Additional:
* Most of Magnus's abilities except Empower will trigger damage through Corrosive Skin.
* Poison Attack and Viper Strike can slow Magnus during Skewer, as well as putting his Blink Dagger on cooldown, preventing him from initiating or re-initiating.

* Any hero who can counter-initiate in anticipation without getting caught in Reverse Polarity: Sven, Omniknight, Enigma, Luna, Naga Siren, Mars, Jakiro, Venomancer, Elder Titan, Faceless Void, Rubick, Keeper of the Light, Pugna, Invoker, Spectre, Alchemist, Treant Protector, Lina, Oracle, Zeus, Shadow Shaman, Phoenix, Razor, Huskar, Batrider, Kunkka, Tidehunter, Wraith King, Sand King, Medusa, Dawnbreaker.

* Illusion heroes like the aforementioned Phantom Lancer or Naga Siren, or heroes that tend to buy Manta Style, like Luna or Juggernaut, will give Slardar a hard time, as his damage is single-targeted.

* Ensnare prevents using any kind of movement abiilties, Making Naga Siren good against heroes who rely on gap-closing abilities to escape: Phantom Assassin, Magnus, Slark, Riki, Faceless Void, Storm Spirit.

* Heroes with damage-increasing passive abilities, such as Viper and Riki, will usually kill Silencer in a short time before he even has time to set up his abilities.

* Melee heroes with low mobility can be kited and killed by Viper: Treant Protector, Kunkka, Alchemist, Troll Warlord, Wraith King, Tiny, Sven.

* Heroes that can slow Charge of Darkness by a huge amount: Venomancer, Viper, Dazzle, Arc Warden, Lion, Huskar, Shadow Shaman, Visage, Undying, Jakiro.

* Heroes with summons and illusions as Spirit Breaker has no strong AoE capabilities to deal with them: Chaos Knight, Phantom Lancer, Terrorblade, Naga Siren, Broodmother, Warlock, Visage, Nature's Prophet, Shadow Shaman, Lycan, Wraith King.

* Viper can bully Alchemist out of mid lane quite easily, forcing him to either retreat into jungle, or stay harassed in lane, and get very few last hits. Vipers break also completely disables Greevil's greed which prevents Alchemist to earn his amazing amounts of money.

* Melee heroes with low mobility can be kited and killed by Viper: Treant Protector, Kunkka, Alchemist, Troll Warlord, Wraith King, Tiny, Sven.

* Melee heroes with low mobility can be kited and killed by Viper: Treant Protector, Kunkka, Alchemist, Troll Warlord, Wraith King, Tiny, Sven.

* In the early game, a Dragon Knight without Black King Bar is basically defenseless against Viper.
* Viper can harass Dragon Knight at any time with his Poison Attack and Nethertoxin.
* Corrosive Skin reduces damage from Dragon Fire and inflicts damage to him.
* Viper Strike disables Dragon Blood, negating his main survivability.
* Viper Strike and Poison Attack can severely slow him down even with his Elder Dragon Form.
Additional:
* Dragon Knight is easily harassed by Poison Attack after the laning stage ends.
* Corrosive Skin protects Viper from Breathe Fire and returns damage.
* Viper Strike can disable Dragon Blood, Dragon's Knight main source of armor and health regeneration.
* Between Poison Attack and Viper Strike, Viper can keep Dragon Knight permanently slowed even in Elder Dragon Form.

* Naga Siren is a natural split-pusher. With Rip Tide, she will easily out-push Nature's Prophet, farming his treants in the process.
* Ensnare prevents Teleportation. Even if he hides inside Sprout, Song of the Siren lasts long enough to prevent him from escaping.
Additional:
* Naga Siren is a natural split-pusher. With a Radiance equipped, she will easily keep the lanes pushed out, therefore keeping backdoor protection enabled and preventing Nature's Prophet from dealing building damage.
* Ensnare can prevent Teleportation. Aghanim's Scepter upgraded Ensnare can also affect Nature's Prophet even if he is spell immune. And Reel In from Aghanim's Scepter can also be used to separate Nature's Prophet from his treant and bring him close to Naga Siren and her team to burst him down.
* Song of the Siren will stop Nature's Prophet from escaping even if he has hidden inside of Sprout. Aghanim's Shard upgraded Song of the Siren can also heal her allies and save them from Nature's Prophet.

* Lycan is a hero focused entirely on single target physical damage and lacks disables or AoE damage. Due to this, he will have difficulties dealing with illusions or Naga Siren's Ensnare.

* Viper's skill set makes him an effective early game ganker against Anti-Mage before he is sufficiently farmed.
* Viper's Corrosive Skin and low mana pool causes him to take little damage from Mana Void.
* Nethertoxin disables Mana Break and Counterspell, weakening both his offense and defense.

* Viper Strike prevents the lifesteal from Ransack.
* Meepo and his clones have a lack of magic resistance, so they're vulnerable to Poison Attack & Viper Strike directed onto one clone.

* Viper Strike prevents buildup of Fiery Soul stacks.
* Corrosive Skin provides magic resistance against Lina's spells. However, Lina can counter this with Silver Edge, a common item on Lina.
* Poison Attack and Viper Strike can burn away Lina's small health pool.

* Naga Siren's illusions from Mirror Image can depush the lanes pushed by the Tempest Double, relieving the pressure.
* Mirror Image can dispel Flux, and the illusions can stop Flux from working to it's full power.
Additional:
* Song of the Siren stops Arc Warden from acting and allows Naga Siren's team to close in on him, past his Magnetic Field.
* Mirror Image dispels Flux. The illusions created from it also disable the slow from Flux if Arc Warden casts it after Mirror Image.
* Arc Warden's playstyle heavily favors split-pushing, which Naga Siren can compete against with her illusions.

* Heroes with Attack speed decreasing skills: Jakiro, Viper Lich

* Illusion-based and multi-unit heroes can take advantage of Chaos Knight's lack of area damage: Naga Siren, Phantom Lancer, Broodmother

* Melee heroes with low mobility can be kited and killed by Viper: Treant Protector, Kunkka, Alchemist, Troll Warlord, Wraith King, Tiny, Sven.

* Heroes with summons and illusions such as Broodmother and Naga Siren, are ill-suited for Wraith King to fight, as he has no source of waveclear.

* Naga Siren can very easily dispel the Reflection with Mirror Image. And Besides Reflection that can be used to detect real Naga Siren, Terrorblade has no other ways to deal with Naga Siren's illusions. And what's worse is that Naga Siren can much easily detect the real Terrorblade due to Conjure Image having illusions having different colors. In addition, Terroblade is not a common Battle Fury nor Mjollnir wielder to counter this problem.
* Aghanim's Scepter upgraded Ensnare will allow Naga Siren to root Terrorblade even ithrough Black King Bar. And with Aghanim's Scepter, Naga Siren can get access to Reel In ability, which can allow her to pull Terrorblade toward herself and her team and away from his illusions, even through Black King Bar.
* Naga Siren can rapidly damage Terrorrblade and weaken Terrorblade's armor with Rip Tide, which combined with Terrorblade's low health and strength gain can almost completely discourage Terrorblade from even being present in teamfights. Rip Tide can also weaken armor of Terrorblade's illusions and damage them.
* Song of the Siren can be used to save an ally whom Terrorblade has used Sunder under the condition Naga Siren is quick enough to do it. And since Terrorblade has no "real" burst damage potential outside from Sunder, Naga Siren will usually have plenty of time to save an allied hero on which Sunder was used. Aghanim's Shard upgraded Song of the Siren can also heal her allies around her for it's duration, which allows Naga Siren to nullify effects of Sunder.
* However, Naga Siren's lack of burst damage can make it difficult for her to burst down Terrorblade before he can use Sunder unless Naga Siren has either Black King Bar or Linken's Sphere to protect herself against it or if she is played as Nuker.
Additional:
* Naga Siren can very easily dispel the Reflection with Mirror Image. And Besides Reflection that can be used to detect real Naga Siren, Terrorblade has no other ways to deal with Naga Siren's illusions. And what's worse is that Naga Siren can much easily detect the real Terrorblade due to Conjure Image having illusions having different colors. In addition, Terroblade is not a common Battle Fury nor Mjollnir wielder to counter this problem.
* Aghanim's Scepter upgraded Ensnare will allow Naga Siren to root Terrorblade even through Black King Bar. And with Aghanim's Scepter, Naga Siren can get access to Reel In ability, which can allow her to pull Terrorblade toward herself and her team and away from his illusions, even through Black King Bar.
* Naga Siren can rapidly damage Terrorrblade and weaken Terrorblade's armor with Rip Tide, which combined with Terrorblade's low health and strength gain can almost completely discourage Terrorblade from even being present in teamfights. Rip Tide can also weaken armor of Terrorblade's illusions and damage them.
* Song of the Siren can be used to save an ally whom Terrorblade has used Sunder under the condition Naga Siren is quick enough to do it. And since Terrorblade has no "real" burst damage potential outside from Sunder, Naga Siren will usually have plenty of time to save an allied hero on which Sunder was used. Aghanim's Shard upgraded Song of the Siren can also heal her allies around her for it's duration, which allows Naga Siren to nullify effects of Sunder.
* However, Naga Siren's lack of burst damage can make it difficult for her to burst down Terrorblade before he can use Sunder unless Naga Siren has either Black King Bar or Linken's Sphere to protect herself against it or if she is played as Nuker.

* Any long duration disables that can pierce through both, Pierce The Veil and Black King Bar are devastating against Muerta: Enigma's Black Hole, Dawnbreaker's Solar Guardian, Axe's Berserker's Call, Naga Siren's Aghanim's Scepter upgraded Ensnare and Reel In from Aghanim's Scepter, Jakiro's Aghanim's Scepter upgraded Macropyre, Bane's Fiend's Grip, Pudge's Dismember, Batrider's Flaming Lasso, Beastmaster's Primal Roar, Grimstroke's Soulbind, Medusa's Stone Gaze, Magnus's Reverse Polarity.

* Heroes with powerful rooting abilities will disable most of Pangolier's skills, a bonus point if it pierces spell immunity since it will also be able to stop Pangolier during his Rolling Thunder: Treant Protector, Meepo, Crystal Maiden, Dark Willow, Underlord, Naga Siren

* Corrosive Skin makes Viper receive less damage from Invoker's spells
* Viper can harass Invoker with his Poison Attack in the early game.
* Viper Strike and Poison Attack can kill Invoker easily if Ghost Walk is on cooldown.

* Mirror Image's illusions can easily walk straight at Dazzle and attack him, due to Dazzle's lack of reliable AoE nukes or disables.
* Ensnare roots Dazzle or his allies, making it harder to stay in range of Dazzle's saving abilities.
* Song of the Siren can be used to initiate a fight with superior positioning, potentially zoning Dazzle's high-impact spells out of the fight.

* Corrosive Skin severely reduces Zeus's damage output throughout the game.
* During the laning stage, Viper can abuse Zeus' reliance on spells by hugging the creep wave. Zeus will take constant damage over time from Corrosive Skin unless he drives Viper from the lane or returns to farming in his absence.
* Prior to buying Blink Dagger or Force Staff, Zeus is fragile and possesses low mobility. Any of Viper's numerous slows can set up an easy kill.
Additional:
* Corrosive Skin counters Zeus in lane by canceling the effects of Clarity as Zeus relies on Arc Lightning to farm and secure last hits.
* Corrosive Skin also increases Viper's magic resistance to shrug off Zeus's magical nukes.
* Nethertoxin breaks Static Field.
* Due to Zeus' poor mobility, Viper Strike will cripple Zeus and will allow Viper and his teammates to land a lot of attacks.

* Tiny has low movement speed and attack speed, making him vulnerable to Viper's slows.
* Corrosive Skin provides magic resistance to lower Tiny's magic burst damage.

* Song of the Siren is very difficult for Rubick to Spell Steal when he is affected by sleep.
* Ensnare and Rip Tide together with some attacks can take Rubick down quickly, due to his low health pool and armor.
* Naga Siren usually buys Diffusal Blade, which may prevent Rubick from using his abilities.
* Mirror Image allows Naga Siren to dodge the incoming stun from Telekinesis (when she is not a target), and it can also dispel Fade Bolt's damage reduction debuff.

* Viper Strike prevents Timbersaw from gaining stacks on Reactive Armor.

* Nethertoxin disables Dawnbreaker's Luminosity. Since she's a melee hero, she needs to close gap to attack and Nethertoxin will be bad for her since she cannot heal.
* Viper Strike and Poison Attack will severely slow her down and combined with Nethertoxin, it will be her death sentence (unless her Celestial Hammer or Solar Guardian are off cooldown). Besides that, chasing her down will be easy due to the slow.

* Poison Attack and Viper Strike allowing to kite and slow Earthshaker significally, putting Blink Dagger on cooldown and preventing him from initiating or re-initiating.
* Nethertoxin breaks Aftershock. The silence from Level 25 talent also prevents Earthshaker from initiating or re-initiating.
Additional:
* Being a melee hero, Earthshaker's movement is liable to suppression by Poison Attack and Viper Strike.
* Earthshaker's kit, with the exception of Enchant Totem, deals magic damage. Corrosive Skin effectively blunts his killing potential with a standard Blink combo among other things.
* Viper Strike can disable Aftershock, which removes the stun and bonus damage from Enchant Totem and Echo Slam.

* Melee heroes with low mobility can be kited and killed by Viper: Treant Protector, Kunkka, Alchemist, Troll Warlord, Wraith King, Tiny, Sven.

* Poison Attack and Viper Strike slows Axe significantly, and puts his Blink Dagger on cooldown, preventing him from initiating. Viper Strike can also break from Counter Helix.
Additional:
* Viper Strike prevents Counter Helix from triggering, which significantly lowers Axe's damage output in the early to mid game.
* Viper's various slows and damage over time prevents Axe from initiating as well as putting his Blink Dagger on cooldown.