* Upheaval does not interrupt Slark too much, as he can just Pounce out of the area.
* Fatal Bonds and Shadow Word can be dispelled by Dark Pact.

* Shadow Dance allows Slark to not be targeted by Unstable Concoction, making Alchemist stun himself and making himself vulnerable to the enemy.
* Dark Pact also allows him to just purge off the stun if timed correctly.
* Essence Shift will steal stats over long durations at a time should Alchemist lack the damage to kill Slark.

* Ice Blast cancels Warlock's Golem's and Shadow Word's healing.
* Cold Feet stuns Warlock if he stands in place, forcing him to stop channeling Upheaval immediately or be forced to stop channeling it by it's stun.

* Ice Blast cancels out Chemical Rage's rapid health regeneration. It can also take advantage of Alchemist's Armlet of Mordiggian toggling, as it will make HP drain insanely fast, essentially killing the bearer in no time.
Additional:
* Ice Blast nullifies the health regeneration granted by Chemical Rage, which Alchemist greatly relies on to stay alive in battle.
* Alchemist tends to build Armlet of Mordiggian which can be deadly during Ice Blast.

* A pre-placed Fire Remnant allows Ember Spirit to escape Upheaval.
* Flame Guard blocks Shadow Word's damage.
* Sleight of Fist allows Ember Spirit to attack from outside of Upheaval's range, and Searing Chains lets him interrupt it.

* Ember's magic damage build is able to burst down Alchemist due to his low strength gain and Alchemist's normal item pick up.

* Ghostship helps your team soak up damage from Chaotic Offering and hit summons hard.
* Tidebringer clears summons later in the game.
* Most of your spells can interrupt Upheaval.

* Tidebringer will deal lots of damage to Alchemist before he builds physical survivability items.
* Torrent and X Marks the Spot can control Alchemist at all stages of the game before he has Black King Bar.
* Ghostship's rum buff will greatly reduce the Alchemist's damage output in teamfights including his Radiance.

* Ursa can shred Warlock's Golems in a few seconds with Fury Swipes and Overpower.

* Chemical Rage will rarely save Alchemist against Ursa's Fury Swipes.
* Enrage allows Ursa to both be a threat to Alchemist and avoid his over time damage.

* Heroes that have small health pools and little to no escape mechanisms are even easier prey for Necrophos. Ghost Shroud's slow will allow him to catch him with them, and get nuked down with his abilities, even preventing retaliation due to Reaper's Scythe's stun. Such heroes include Crystal Maiden, Witch Doctor, Warlock or Shadow Fiend.

* Reaper's Scythe can kill Alchemist before Chemical Rage has the time to heal him.
* Ghost Shroud can prevent Alchemist from attacking Necrophos, as well as make him immune to Acid Spray and Unstable Concoction damage.
* Heartstopper Aura will do damage as long as Necrophos is alive based on health percentage, which is a problem for a strength hero such as Alchemist.

* With God's Strength, Warlock Golem goes down in a matter of seconds. The two weaker golems granted by Aghanim's Scepter will fare worse due to Great Cleave hitting both.
* Storm Hammer upgraded with Aghanim's Scepter dispels Shadow Word.
Additional:
* God's Strength combined with Great Cleave destroys Chaotic Offering golems within seconds.
* Warcry gives Sven and his allies armor to help against Warlock's Golem's heavy physical damage and movement speed to help escape Upheaval.
* Storm Hammer disrupts Upheaval.

* Heroes who struggle to fight back against Sven at any point in the game are at a severe disadvantage: Alchemist, Anti-Mage, Crystal Maiden.

* Because all of Warlock's abilities are active abilities, silences can make his impact in fights minimal. Be cautious of heroes that carry silences like Death Prophet, Puck, and the aforementioned Silencer.

* Melee heroes that get kited easily have hard times dealing with Puck without any lockdowns, as Puck is one of the most mobile heroes. Heroes like Sven, Lifestealer, Ursa and Alchemist may have problems to get to Puck without proper initiation items. They also lack reliable lockdowns, as their disables are easily avoidable for Puck, or are just a soft disable.

* Shapeshift allows Lycan to escape from Upheaval with maximum movement speed.
* Warlock doesn't have a good solution to deal with Lycan's wolves from Summon Wolves.

* Alchemist likes to farm fast and be ahead, unfortunately Lone Druid likes to do the same by taking towers.
* Acid Spray will never prove a threat to Lone Druid or his Spirit Bear.
* Chemical Rage may not prove so useful once Lone Druid procs entangled keeping him in place.
* Monkey King Bar is a very good choice on Lone Druid's Spirit Bear and it directly counters any potential Radiance from Alchemist.
* Assault Cuirass is another very good Spirit Bear item that further makes Alchemist vulnerable to physical damage, which is all Lone Druid does.
* Alchemist is not the kind of hero who wants to go on single target summon units, by the time he has killed the Spirit Bear his teammates might had already been slayed by his teammates. Not to mention Lone Druid can just resummon it, even if he is successful.

* Mana Break prevents Warlock from casting his spells, particularly in the laning phase.
* Blink allows Anti-Mage to escape from Upheaval.
* Counterspell reduces damage from Shadow Word and Warlock's Golem's Permanent Immolation passive. Additionally, it can reflect Shadow Word and Fatal Bonds.
* Mana Void deals heavy damage after Anti-Mage has drained Warlock's large mana pool.

* Because Warlock's abilities are all active abilities, Silencer can make his impact minimal.
* Arcane Curse prevents Warlock from using his abilities without increasing it's duration, which since all of Warlock's abilities are actives it is very effective against him.
* Last Word can prevent Warlock from casting his Fatal Bonds, Chaotic Offering, and Upheaval combo.
* Global Silence can nullify Warlock's impact in fights by preventing him from casting Fatal Bonds and Chaotic Offering, or by interrupting his Upheaval.

* Surge allows for Dark Seer and his allies to escape from Upheaval due to it ignoring any slow.

* Alchemist's reliance on fast attack speed to do single-target damage makes him vulnerable to Static Link. It also goes through Black King Bar, which is a standard item on Alchemist.
* Eye of the Storm is great against high health strength heroes as it reduces their survivability to physical damage.
* Razor has early lane push to counter Acid Spray.

* Corrosive Haze followed by Slithereen Crush takes advantage of Alchemist's main weakness, being physical damage before he has the change to improve his surviability with items.
* Bash of the Deep will deal lots of damage during the laning phase.

* Weaver's Shukuchi allows him to escape from Warlock's Upheaval with high move speed.
* Time Lapse allows Weaver to ignore damage from Warlock's Golem and escape.

* Impale and Spiked Carapace interrupts Upheaval with ease.
* Warlock's low health pool, mobility, and high intelligence gain makes him a prime target for Nyx Assassin's burst damage.

* Skywrath Mage can easily harass Alchemist in the laning phase with multiple Arcane Bolts. Additionally, if Alchemist is in the process of throwing an Unstable Concoction, and has no way to dispel Ancient Seal, the self stun becomes an easy set up for Mystic Flare.
* Caution, however, as a decently farmed Alchemist with {Item ID:Radiance} and {Item ID:Manta Style} can easily send illusions to harass and force Skywrath Mage out.

* Axe can force Alchemist to attack him with Berserker's Call. High attack speed from Chemical Rage will cause Counter Helix to proc multiple times.
* This can get worse if axe has Blade Mail, which then returns all damage to Alchemist himself.
* Axe's abilities can pierce through Black King Bar, which is a common item for Alchemist.
* Berserker's Call grants Axe a huge bonus armor, which greatly counters Alchemist's physical damage for the most part.

* Quas-Exort Invoker can win the mid lane easily against Alchemist because Quas regeneration will nullify Acid Spray's damage over time and Exort damage bonus will allow Invoker to out last hit Alchemist.

* Alchemist is a well-known Radiance carrier among other auras your illusions will benefit from. They also get the extra move speed and reduced base attack time from his Chemical Rage, and it's even better if you can catch him as his own rage is about to expire.
* Disruption will buy enough time for all allies to retreat when Alchemist starts to activate Unstable Concoction.

* Untouchable greatly reduces Chemical Rage's attack speed advantage.

* Visage can quickly kill heroes with low to medium base armor and no innate escape mechanism. Examples include Alchemist, Crystal Maiden and Zeus.

* Because all of Warlock's abilities are active abilities, silences can make his impact in fights minimal. Be cautious of heroes that carry silences like Death Prophet, Puck, and the aforementioned Silencer.

* Warlock is a very strong hero when positioned correctly, and his long cast range helps him with this. However, some Heroes might disrupt or sneakily pass through his allies and deal with him, preventing him from doing his job. Such heroes include Chaos Knight, Spirit Breaker, Riki, and more.

* Clinkz can use Burning Army in teamfights which will cause a problem for Alchemist.

* Heroes who rely on summons will see them destroyed easily by Overwhelming Odds: Lycan, Arc Warden, Warlock, Chen

* In general, attacks of the melee heroes who are entirely reliant on dealing physical damage and/or have very little to no area-of-effect abilities will make Underlord tickle and will have no effect against him, and will be unable to ambush Underlord and his team if Underlord chooses to use Dark Rift to get to a designated point of the map: Phantom Assassin, Terrorblade, Troll Warlord, Drow Ranger, Phantom Lancer, Chaos Knight, Sven, Wraith King, Bounty Hunter, Alchemist, Templar Assassin, Nyx Assassin, Bane.

* Heroes with channeling spells are very easy targets for Jakiro's abilities: Crystal Maiden, Dawnbreaker, Enigma, Pudge, Shadow Fiend, Shadow Shaman, Warlock.

* Heroes who are melee but cannot fight back against Eclipse will really struggle with Luna: Monkey King, Alchemist, Timbersaw.

* Warlock is a very strong hero when positioned correctly, and his long cast range helps him with this. However, some Heroes might disrupt or sneakily pass through his allies and deal with him, preventing him from doing his job. Such heroes include Chaos Knight, Spirit Breaker, Riki, and more.

* Heroes who rely on skills to become a heavy hitter in a certain amount of time can waste their timing because of a lucky Lucky Shot's disarm: Terrorblade, Sven, Clinkz, Windranger, Alchemist, Dragon Knight, Legion Commander

* Warlock is a very strong hero when positioned correctly, and his long cast range helps him with this. However, some Heroes might disrupt or sneakily pass through his allies and deal with him, preventing him from doing his job. Such heroes include Chaos Knight, Spirit Breaker, Riki, and more.

* Pugna's Decrepify makes sure that either Alchemist is unable to hit anyone while also being slowed and susceptible to magical damage, or can protect an ally from physical attacks. Besides, Pugna can push early on, when Alchemist is not strong enough to repel it, so by the time Alchemist comes online, he might be forced to sit in base.

* Feast is good against high health strength heroes such as Alchemist.
* Rage allows Lifestealer to not be targetable by Unstable Concoction, possibly making Alchemist stun himself.

* Alchemist has very bad armor and does not build armor items for the large majority of his build, so Jingu Mastery and Wukong's Command can be very deadly.
* Desolator, Sange and Yasha or Diffusal Blade can all be purchased to increase your damage against Alchemist or just to keep your movement speed high enough to match him while Chemical Rage is active.
* Monkey King is an agility hero and scales with armor, so Acid Spray loses it's effectiveness later in the game.