* Enrage will make it very difficult to burst him down.
* Zeus has little armor, HP and mobility; Ursa's favorite kind of target.

* Chemical Rage will rarely save Alchemist against Ursa's Fury Swipes.
* Enrage allows Ursa to both be a threat to Alchemist and avoid his over time damage.

* Zeus laneing against Ember is going to be punished with Sleight of Fist due to his low health pool
* Zeus's chip damage from Arc Lightning and other spells is nullified from Ember's Flame Guard.

* Ember's magic damage build is able to burst down Alchemist due to his low strength gain and Alchemist's normal item pick up.

* Heroes with long range abilities are also able to touch Zeus, such as Clockwerk, Kunkka, Puck, Skywrath Mage, Spirit Breaker, Tusk and others.

* Skywrath Mage can easily harass Alchemist in the laning phase with multiple Arcane Bolts. Additionally, if Alchemist is in the process of throwing an Unstable Concoction, and has no way to dispel Ancient Seal, the self stun becomes an easy set up for Mystic Flare.
* Caution, however, as a decently farmed Alchemist with {Item ID:Radiance} and {Item ID:Manta Style} can easily send illusions to harass and force Skywrath Mage out.

* Corrosive Skin severely reduces Zeus's damage output throughout the game.
* During the laning stage, Viper can abuse Zeus' reliance on spells by hugging the creep wave. Zeus will take constant damage over time from Corrosive Skin unless he drives Viper from the lane or returns to farming in his absence.
* Prior to buying Blink Dagger or Force Staff, Zeus is fragile and possesses low mobility. Any of Viper's numerous slows can set up an easy kill.
Additional:
* Corrosive Skin counters Zeus in lane by canceling the effects of Clarity as Zeus relies on Arc Lightning to farm and secure last hits.
* Corrosive Skin also increases Viper's magic resistance to shrug off Zeus's magical nukes.
* Nethertoxin breaks Static Field.
* Due to Zeus' poor mobility, Viper Strike will cripple Zeus and will allow Viper and his teammates to land a lot of attacks.

* Viper can bully Alchemist out of mid lane quite easily, forcing him to either retreat into jungle, or stay harassed in lane, and get very few last hits. Vipers break also completely disables Greevil's greed which prevents Alchemist to earn his amazing amounts of money.

* Heroes who have most or all their abilities (damage or disable) unable to pierce spell immunity: Keeper of the Light, Lina, Lion, Zeus.

Additional:
* Rage is very useful against Zeus, as it negates magic damage and provides spell immunity. In addition, the increased attack speed can tear Zeus apart in combination with Open Wounds.
* Lifestealer can avoid Thundergod's Wrath with Infest.

* Feast is good against high health strength heroes such as Alchemist.
* Rage allows Lifestealer to not be targetable by Unstable Concoction, possibly making Alchemist stun himself.

* Even though Pugna's low HP means that he can be quickly burst down, his Nether Ward heavily punishes casters whose spells cost a lot of mana, like Zeus. Casting 4 of his active spells, including Nimbus, close to an enhanced level 4 Nether Ward, can make the ward deal up to 1750 magical damage.
* Decrepify can further increase the damage dealt by Nether Ward upon Zeus. However, if used on Pugna himself or on one of his allies, it will amplify the damage done by Zeus' abilities.

* Pugna's Decrepify makes sure that either Alchemist is unable to hit anyone while also being slowed and susceptible to magical damage, or can protect an ally from physical attacks. Besides, Pugna can push early on, when Alchemist is not strong enough to repel it, so by the time Alchemist comes online, he might be forced to sit in base.

* Heroes with long range abilities are also able to touch Zeus, such as Clockwerk, Kunkka, Puck, Skywrath Mage, Spirit Breaker, Tusk and others.

* Tidebringer will deal lots of damage to Alchemist before he builds physical survivability items.
* Torrent and X Marks the Spot can control Alchemist at all stages of the game before he has Black King Bar.
* Ghostship's rum buff will greatly reduce the Alchemist's damage output in teamfights including his Radiance.

* Visage can quickly kill heroes with low to medium base armor and no innate escape mechanism. Examples include Alchemist, Crystal Maiden and Zeus.

* Visage can quickly kill heroes with low to medium base armor and no innate escape mechanism. Examples include Alchemist, Crystal Maiden and Zeus.

* Heroes with long range abilities are also able to touch Zeus, such as Clockwerk, Kunkka, Puck, Skywrath Mage, Spirit Breaker, Tusk and others.

* Melee heroes that get kited easily have hard times dealing with Puck without any lockdowns, as Puck is one of the most mobile heroes. Heroes like Sven, Lifestealer, Ursa and Alchemist may have problems to get to Puck without proper initiation items. They also lack reliable lockdowns, as their disables are easily avoidable for Puck, or are just a soft disable.

* Heroes who cannot prevent Sven from killing supports will always be at a disadvantage in fights such as Lina, Slark and Zeus.

* Heroes who struggle to fight back against Sven at any point in the game are at a severe disadvantage: Alchemist, Anti-Mage, Crystal Maiden.

* Thundergod's Wrath strikes only the first Meepo.
* Zeus has low mobilty so consecutive Earthbinds are easy to hit and he'll quickly die from Poofs.

* Alchemist likes to farm fast and be ahead, unfortunately Lone Druid likes to do the same by taking towers.
* Acid Spray will never prove a threat to Lone Druid or his Spirit Bear.
* Chemical Rage may not prove so useful once Lone Druid procs entangled keeping him in place.
* Monkey King Bar is a very good choice on Lone Druid's Spirit Bear and it directly counters any potential Radiance from Alchemist.
* Assault Cuirass is another very good Spirit Bear item that further makes Alchemist vulnerable to physical damage, which is all Lone Druid does.
* Alchemist is not the kind of hero who wants to go on single target summon units, by the time he has killed the Spirit Bear his teammates might had already been slayed by his teammates. Not to mention Lone Druid can just resummon it, even if he is successful.

* Zeus almost exclusively relies on magical damage, which is heavily reduced by Counterspell.
* Zeus' complete lack of mobility makes him very easy for Anti-Mage to chase down with Blink.
* Zeus likes to stand in the back during team fights, but Anti-Mage can easily Blink to close the distance.
Additional:
* Anti-Mage can burn mana, which is a big problem for a spellcaster like Zeus that heavily relies on it.
* Counterspell decreases magical damage taken from Zeus.
* Zeus' high intelligence and mana pool makes him a perfect target for Mana Void.

* Zeus' main source of damage is his low cooldown, high damage spells - meaning Last Word and Global Silence will pretty much take him out of the game for the duration.
* Zeus likes to spam his abilities, which makes him vulnerable to Arcane Curse.
* If Zeus dies near Silencer, he will begin to lose intelligence, reducing his mana pool, mana regen, and attack damage. Furthermore, if the game is long and Zeus dies often, the intelligence losses will also reduce his spell damage.
Additional:
* Silencer's Global Silence will render Zeus useless for 6 seconds in a team fight.
* Arcane Curse will punish Zeus for casting spells, which can cause continuous damage to him should he continue to cast spells.
* Last Word can silence Zeus and prevent him from spamming his spells.
* Silencer often builds Orchid Malevolence (or Bloodthorn) which can be used on spell casters like Zeus, forcing him to invest in a Linken's Sphere.

* Alchemist's reliance on fast attack speed to do single-target damage makes him vulnerable to Static Link. It also goes through Black King Bar, which is a standard item on Alchemist.
* Eye of the Storm is great against high health strength heroes as it reduces their survivability to physical damage.
* Razor has early lane push to counter Acid Spray.

* Zeus can deal a huge amount of damage, but he lacks defensive abilities, such as good mobility or resistance. Due to that, he doesn't like to be touched by any means. Heroes with higher damage output and good mobility will often get easily near Zeus and trade damage (eventually causing Zeus's downfall). Such Heroes include: Lycan, Slark, Storm Spirit, Spectre and others.

* Shadow Dance allows Slark to not be targeted by Unstable Concoction, making Alchemist stun himself and making himself vulnerable to the enemy.
* Dark Pact also allows him to just purge off the stun if timed correctly.
* Essence Shift will steal stats over long durations at a time should Alchemist lack the damage to kill Slark.

* Ice Blast cancels out Chemical Rage's rapid health regeneration. It can also take advantage of Alchemist's Armlet of Mordiggian toggling, as it will make HP drain insanely fast, essentially killing the bearer in no time.
Additional:
* Ice Blast nullifies the health regeneration granted by Chemical Rage, which Alchemist greatly relies on to stay alive in battle.
* Alchemist tends to build Armlet of Mordiggian which can be deadly during Ice Blast.

* None of Zeus's abilities can damage a Juggernaut in Blade Fury.
* Zeus's short attack range makes it difficult for him to target a well-placed Healing Ward. His frequent use of Arc Lightning will have almost no effect on allies being healed by Juggernaut.
* Zeus has no way to defend himself, even if Juggernaut cannot use Blade Fury. He can be easily taken out if cornered, sometimes even without Omnislash.
Additional:
* Blade Fury negates all magical damage from Zeus.
* Omnislash can easily take down Zeus. However, be aware that most players will get a Eul's Scepter of Divinity or a Ghost Scepter against Juggernaut.

* Axe can force Alchemist to attack him with Berserker's Call. High attack speed from Chemical Rage will cause Counter Helix to proc multiple times.
* This can get worse if axe has Blade Mail, which then returns all damage to Alchemist himself.
* Axe's abilities can pierce through Black King Bar, which is a common item for Alchemist.
* Berserker's Call grants Axe a huge bonus armor, which greatly counters Alchemist's physical damage for the most part.

* Zeus likes to stay far back in fights, dealing his damage uninterrupted, but once he gets hooked into the fight, he usually dies very quickly.
* Pudge's high strength from Flesh Heap makes it very hard for Zeus to burst him down.
* Zeus' low health pool makes him very vulnerable to the damage from Meat Hook, Rot and Dismember.
Additional:
* Meat Hook's high range allows Pudge's team to drag Zeus in the middle of the fight and abuse his frailty.
* Flesh Heap's health and magic resistance bonus makes Pudge exceptionally resistant to Zeus' nukes. In later stages of the game, Zeus is usually unable to seriously damage Pudge at all. Even Static Field, which deals damage based on a percentage of the enemy's health, won't be doing much.
* Even if Zeus buys a Black King Bar, Meat Hook and Dismember still disable him for a long time, usually causing Zeus' quick death.
* Zeus is vulnerable to early ganks, which Pudge excels at.

* Quas-Exort Invoker can win the mid lane easily against Alchemist because Quas regeneration will nullify Acid Spray's damage over time and Exort damage bonus will allow Invoker to out last hit Alchemist.

* Marci on the midlane will win the laning phase against Zeus almost every time, as her powerspike at level 6 will decimate Zeus' low health pool and force him to stay far back.
* Even before level 6, Dispose and Sidekick can easily take half of Zeus' health if he is in range of Dispose.

* Time Dilation can limit Zeus to casting his abilities only once in a fight, effectively serving as a 6/8/10/12 second silence.
* Time Walk negates Zeus's burst damage.
* Chronosphere makes Zeus the best target for Void because of his low mobility.

* Chaos Knight's high health pool makes him resistant to Zeus' burst damage. Phantasm can dispel Veil of Discord, a typical item purchased by Zeus.
* Zeus is easily overwhelmed by Chaos Knight's strong illusions, as Arc Lightning is not enough to kill them fast enough to have any impact.
* Zeus' low base armor makes him extremely vulnerable to Chaos Knight's high damage output and armor reduction.

* Alchemist is a well-known Radiance carrier among other auras your illusions will benefit from. They also get the extra move speed and reduced base attack time from his Chemical Rage, and it's even better if you can catch him as his own rage is about to expire.
* Disruption will buy enough time for all allies to retreat when Alchemist starts to activate Unstable Concoction.

* Once you get a Black King Bar, squishy spellcasters like Zeus, Skywrath Mage and others will be probably easy to deal with.

* Spirit Siphon does a lot of magical damage, especially in the early game. This allows her to demolish low health heroes such as Zeus, Pugna, especially when combined with her other spells.

* Heroes with low mobility that rely on spells: Zeus, Lina, Crystal Maiden.

* In general, attacks of the melee heroes who are entirely reliant on dealing physical damage and/or have very little to no area-of-effect abilities will make Underlord tickle and will have no effect against him, and will be unable to ambush Underlord and his team if Underlord chooses to use Dark Rift to get to a designated point of the map: Phantom Assassin, Terrorblade, Troll Warlord, Drow Ranger, Phantom Lancer, Chaos Knight, Sven, Wraith King, Bounty Hunter, Alchemist, Templar Assassin, Nyx Assassin, Bane.

* As a spellcaster, silences will nullify him entirely. Some notable examples are Death Prophet, Drow Ranger, Bloodseeker, Disruptor and many others.
* Doom, as usual, fits this description nicely.

* Heroes with long range abilities are also able to touch Zeus, such as Clockwerk, Kunkka, Puck, Skywrath Mage, Spirit Breaker, Tusk and others.

* Heroes with long range abilities are also able to touch Zeus, such as Clockwerk, Kunkka, Puck, Skywrath Mage, Spirit Breaker, Tusk and others.

* Zeus can deal a huge amount of damage, but he lacks defensive abilities, such as good mobility or resistance. Due to that, he doesn't like to be touched by any means. Heroes with higher damage output and good mobility will often get easily near Zeus and trade damage (eventually causing Zeus's downfall). Such Heroes include: Lycan, Slark, Storm Spirit, Spectre and others.

* As a spellcaster, silences will nullify him entirely. Some notable examples are Death Prophet, Drow Ranger, Bloodseeker, Disruptor and many others.
* Doom, as usual, fits this description nicely.

* Heroes with summons that are destroyed by a fixed number of attacks: Undying's Tombstone, Gyrocopter's Homing Missile, and Zeus's Nimbus.

* Heroes with long range abilities are also able to touch Zeus, such as Clockwerk, Kunkka, Puck, Skywrath Mage, Spirit Breaker, Tusk and others.

* As a spellcaster, silences will nullify him entirely. Some notable examples are Death Prophet, Drow Ranger, Bloodseeker, Disruptor and many others.
* Doom, as usual, fits this description nicely.

* Heroes that depend on disrupting fights with ability combos or big ultimate abilities are vulnerable to the long stun of Fiend's Grip: Disruptor, Death Prophet, Enigma, Faceless Void, Invoker, Lich, Magnus, Mars, Medusa, Outworld Destroyer, Phoenix, Puck, Queen of Pain, Shadow Fiend, Treant Protector, Underlord, Winter Wyvern, Witch Doctor, Zeus.

* Heroes who rely on skills to become a heavy hitter in a certain amount of time can waste their timing because of a lucky Lucky Shot's disarm: Terrorblade, Sven, Clinkz, Windranger, Alchemist, Dragon Knight, Legion Commander

* Heroes with a lot of burst damage, especially those who rely on casting spells: Lina, Zeus.

* Zeus burst damage can be reduced by Dispersion and reflect some of the damage back to Zeus himself.
* Zeus has low mobility and stays in backlines, Spectral Dagger or Haunt can easily catch him as he has no escape mechanism.
* Since Zeus has low HP, Spectral Dagger and Desolate will quickly tear Zeus down when he's alone.

* Although Lightning Bolt and Thundergod's Wrath can reveal Templar Assassin during Meld, Zeus nonetheless has no way to deal with Refraction.
* Zeus is a rather squishy hero, falling easily to Templar Assassin's high burst damage.
Additional:
* Refraction blocks all of Zeus' damage and Zeus has no innate way of removing the instances quickly.
* Meld helps burst down Zeus' small health pool while he's still working through the Refraction instances.
* Psi Blades allow her to harass and zone Zeus in lane.
* Templar Assassin usually buys Blink Dagger, enabling her to quickly close the gap to Zeus' defensive positioning.